Akol004663.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles koliensis
Gene Symbol
-
Assembly
GCA_000956275.1
Location
JXXB01018666.1:224-3399[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 4.2 3.5e+02 2.0 0.8 1 15 51 65 51 68 0.80
2 13 0.00096 0.082 13.4 3.3 2 23 418 439 417 439 0.97
3 13 0.023 2 9.0 4.3 2 23 446 467 445 467 0.97
4 13 0.045 3.9 8.1 1.6 1 23 477 499 477 499 0.96
5 13 0.79 67 4.2 0.0 3 23 524 551 523 551 0.81
6 13 0.34 29 5.4 0.2 2 23 558 579 557 579 0.95
7 13 5e-05 0.0043 17.4 0.2 1 20 617 636 617 637 0.97
8 13 0.0041 0.35 11.4 1.4 2 23 646 667 645 667 0.95
9 13 0.00015 0.013 15.9 1.0 2 23 673 694 672 694 0.92
10 13 0.67 57 4.4 2.9 2 23 703 724 702 724 0.95
11 13 9.2e-06 0.00079 19.7 1.7 3 21 732 750 730 751 0.95
12 13 3.9e-05 0.0033 17.8 2.0 1 23 762 784 762 784 0.99
13 13 0.00037 0.031 14.7 2.5 1 23 790 813 790 813 0.98

Sequence Information

Coding Sequence
ATGAGGGACGTCGATAAAAGTTGTGCGCTGTGTTTATCGCCAGACGCAAAATGGTACCTGGAAGTGTTCAATGAAGAAAATATAGCCCTCGAAATGGCAGTGATCATATCGAAGCATCTTTGGTTCGACCTCAAACCATCATTGCACCCGTACGTTTGTACCGATTGTTGGACAAGTGTGTATGATTTTCATCAATTCTACACAAAACTTGAAAACGTATATAACCAGGGACAGGTCAACGAAATGGTCGAAGTATTAGACATCGAGTTTCTGGATGAGGATGCCGAGGAACTTCGTTTTCAGATAAGGCATACATCCAGTATCAAGGATAACGACGACCTTGCCAGACCAAAACGTGCATCCAACGTACCGCAAAGGTATCACAAAAGCAATGAACATCCAGACAAGAAACAAAGTATAGGCCCAGATGACGAGGAATACATTTTAGGGGATGAAAATGATGTTTACGAAAATAATGACATCGATAACGATTCCCTCGAACACGACGAAAGCGCTGATACATCGTAcgtggaggaagaaaagaaatccgATAAAATTGGGCAACGGTCTACAATCGCTATCGATATTCTGGATGCTCAAGAGCAGCCAGTAAAACGGCGTCGTGGTCGTCCACCGAAGCGTAAGGTACCGGATGATGAAGTGCAAACTTCCagtgtggaaaaaaagaaacaaaatccaaatGCAACCCAATCCTCATCCATCGTGTCATCCGCGGACCAACCGGTAAAGCGTGGACGTGGTAGACCACCGAAGTTGAAACCGCTTGACGCCGGTGTCGTTCCGGCATCAGCACCTCATACACCAACCATAAAGAAGGAGATAAAATCGGAATTTGGCGACAGCGATAAAGAAGCAACACCGAACACGTCGAAGTCAGGGGTACATCCCGAACGTAGATCGACCCGTGTTCGGAAGGTAAAGTATCTGAGTGAAACCGAAGTGGATACCGCGGAAGACGAAGAAAGCGAACTGAACGAGAGTGACATGGAGGAATGTGATGATCCGGAATACGAGGAAAAGCTAGAGCTGCAAAGGAAGCTGAACATGGACGATTATGAGTTCTACGAGTATCAGTGTAACATGGAATCGGAGCAGTTTGCGCGCGATAACAGGATATTTCAGTACGTGGATGAGTTTATTTGCCACTATTGCGTGGAAAAGGTGCATTTCAAGCGGTTTGCCGAGGCGGACGTGCACTATCGAGTGGAGCACAAGCAGCCCCCGTTCCTGAAGTGCCCaaagtgtgaaaagaaatgtCACAACCCAGGCATGTTCATCAGCCATATGGAAACGCACGACGATCCGGAAAAGTCTAGGTGCCACATTTGCGGCAAGCTAACCGATTGCAATATCTCGCTAAAGAAGCATATGCGCGTACATCAAGGAAAGCTTGAGCAGAACCTGCCTTATCCATGCAGTCGCTGCAAGCGAAAGTTCGAGACCGAAGAGCAGCGCGACAAGCACGAGAAGCTACACGTACCGAAGCCGTTCGTACCGCGCGACGAGGGTCCTGATCTGGAGGTGCTCGAGTTCTACAAGCGAATCTTCTGCGACATATGCGAGGAGGGCGAACCGGAATCGACCTCGTTCGACAACCTGTGGGCTCTGCGAACGCACATGGCCAACGAACACCGGAAGAGCCTGTTCGTCCGGTGCCCCGTGTGCTTCAAGCGCCAGATCAATCGCACCCAAGTCATCACTCACATTGACATGCACAAAAATCCGGACAAGTATCGATGTGAAGTTTGCCAGGAAGTTCATCAGGATCTGCCGCGACACATGATGAAGGCGCACACACCCAACACGAAGGAAGAGGTGGAGAAAAAGTACGAATGTGAACAGTGCGGGCGAATGTTCAACTACTTGACCAACTTAAAAATGCACATCGATTGCATTCACAGTTTAAAGGACGTTCGATGTAACATTTGCGACAAATACTTCAACTATAAGGCGTACCAAACGCACAAGCGTAAGGCACACACCGACCAATTGCTGATGTGCGAACACTGTCCGCGGATGTTCAAGAATCGCAAAGCGTTAGAAGCTCATAAGGGCTATCACGACGCGAGCCTGCTGAAGCTTACGAAATGTGAGCTGTGCGGGAAACAGATACGCGTCTGCAGCATGTCGAAACACATGAAAACGATGCATTCGGAGGAGGATCCGATCGATTGCGAGCTGTGTGGAAAAACGTTCCGTACCTCGTTCCACATGAAGCGGCATCAGCGCAACACGTGTGAGGCGACGATGGATTCGCGCTCGTTCAAGTGTGAGGTGTGCGGCAAGGGATTCTGTACAAAGCTGACGATGGTTGAGCACATGACGACACATACGCGCGCGAACCAGTACCAGTGCGCGTTCTGCTTCAAATCGTTCGGATACATCTCGAATTTGTACAAGCACCGCAAAAAGGCACATCCGCTCGAATGGCAAGAAGTACAGCAGCACCCCGAGGAAGGAATAGCTACTGTGattgttgtgaaaaattaa
Protein Sequence
MRDVDKSCALCLSPDAKWYLEVFNEENIALEMAVIISKHLWFDLKPSLHPYVCTDCWTSVYDFHQFYTKLENVYNQGQVNEMVEVLDIEFLDEDAEELRFQIRHTSSIKDNDDLARPKRASNVPQRYHKSNEHPDKKQSIGPDDEEYILGDENDVYENNDIDNDSLEHDESADTSYVEEEKKSDKIGQRSTIAIDILDAQEQPVKRRRGRPPKRKVPDDEVQTSSVEKKKQNPNATQSSSIVSSADQPVKRGRGRPPKLKPLDAGVVPASAPHTPTIKKEIKSEFGDSDKEATPNTSKSGVHPERRSTRVRKVKYLSETEVDTAEDEESELNESDMEECDDPEYEEKLELQRKLNMDDYEFYEYQCNMESEQFARDNRIFQYVDEFICHYCVEKVHFKRFAEADVHYRVEHKQPPFLKCPKCEKKCHNPGMFISHMETHDDPEKSRCHICGKLTDCNISLKKHMRVHQGKLEQNLPYPCSRCKRKFETEEQRDKHEKLHVPKPFVPRDEGPDLEVLEFYKRIFCDICEEGEPESTSFDNLWALRTHMANEHRKSLFVRCPVCFKRQINRTQVITHIDMHKNPDKYRCEVCQEVHQDLPRHMMKAHTPNTKEEVEKKYECEQCGRMFNYLTNLKMHIDCIHSLKDVRCNICDKYFNYKAYQTHKRKAHTDQLLMCEHCPRMFKNRKALEAHKGYHDASLLKLTKCELCGKQIRVCSMSKHMKTMHSEEDPIDCELCGKTFRTSFHMKRHQRNTCEATMDSRSFKCEVCGKGFCTKLTMVEHMTTHTRANQYQCAFCFKSFGYISNLYKHRKKAHPLEWQEVQQHPEEGIATVIVVKN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-