Akol013318.1
Basic Information
- Insect
- Anopheles koliensis
- Gene Symbol
- grau
- Assembly
- GCA_000956275.1
- Location
- JXXB01029428.1:965-2134[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.67 57 4.4 0.1 2 21 61 80 60 83 0.87 2 10 3.2 2.7e+02 2.3 2.3 6 23 93 110 91 110 0.89 3 10 5.3e-06 0.00045 20.5 1.2 1 23 116 139 116 139 0.96 4 10 3.9e-05 0.0033 17.8 2.7 1 23 147 169 147 169 0.95 5 10 1.6e-05 0.0014 19.0 1.4 2 23 178 200 178 200 0.97 6 10 0.00086 0.073 13.6 0.1 2 23 207 228 206 228 0.96 7 10 0.59 50 4.6 8.2 1 23 238 261 238 261 0.96 8 10 0.0002 0.017 15.6 1.6 2 23 268 289 267 290 0.94 9 10 6.2e-05 0.0053 17.1 3.5 1 23 296 318 296 318 0.97 10 10 0.0085 0.72 10.4 1.4 1 23 324 347 324 347 0.91
Sequence Information
- Coding Sequence
- ATGCTTCATCATCCCGAACCGGACGGGACGGAAGGAACGGTGCAGCCGTTATCGACCCCCGTTCCGAATGGTACCTCGGATCCAACGGACGACAAGCTAACCGAATCGCACTACCGAACGCGCGTCTCCGCGGAGGAGATCAGCGCCCAGGACGAGTTCATCAAGCGCTACTGTGTGCTGAGCTGCACGCAGTGCGAGTACATCGCCGACACGTTCGCCCAGCTGCGGCAGCACGGCACGGAGGCGCACGAGCTGCGCGGCTGCGAGGTGTTCTGCTGCGATCGCACCTACAGCAAGCGCCAGTCGCTGTACGATCACTGTCTCGTGCACGAAAACCCCGACCGCTTCCGGTGCAGCGTGTGCGGCAAGCAGTACTCGAGCAGCCGGAGCCTCCAGGCGCACAAAACGCGCATCCACACGCCCGCCGCCGAGCGTCCGTTCTGCTGCGAGGTGTGCGGCGAAACGTTCGTCAAGTCGTACCTGCTGATGCAGCACATGGTGCACCATCTGGCGAAGCAGAAGAAGCTCAACTACTGCAACGAGTGTCAGCGATCGTTCACGACGGCGCGGGTGCTGAAGAGCCACCAGCAGACGTACCACGGCGCAAGCTTCAGCTGGATCTGCGACGTGTGCGCGAAGGGCTTCAACAGCCGGCCGCTCTTCGAGAACCATCGGCTAACGCACTCGGTCGAGGGCAAGACGCAGCTCAAGCACCAGTGCGAGGAGTGCCACAAGTGGTTGCGCAACAAAAAGTCctaccagcagcaccggatCCGCTGCCACGCGAACAACGGTCCGGTGAAGTGCCAGTTCTGCGGCAAGGAGTCGGTAAACGCGAGCGCCCTGCAATCGCACATCCACCTGCACCATGCCGAGCGGCCGGAATATCCCTGCAAGCACTGCAAGAAAAGCTTCAAGACGTCGTTGCGGTTGCGCGAGCACGAGGCGACCCACACCGGCACCGTCCTCTACCGCTGCCCGTGGTGTCCGCGCACGTTCGCGTGCGGTTCCAACATGTACAAGCACAAGAAGGCGGGCCACCCGATCGAGTGGGCCGCCTCGGTCAACAAGCGGTTCGGGGAGCGATGA
- Protein Sequence
- MLHHPEPDGTEGTVQPLSTPVPNGTSDPTDDKLTESHYRTRVSAEEISAQDEFIKRYCVLSCTQCEYIADTFAQLRQHGTEAHELRGCEVFCCDRTYSKRQSLYDHCLVHENPDRFRCSVCGKQYSSSRSLQAHKTRIHTPAAERPFCCEVCGETFVKSYLLMQHMVHHLAKQKKLNYCNECQRSFTTARVLKSHQQTYHGASFSWICDVCAKGFNSRPLFENHRLTHSVEGKTQLKHQCEECHKWLRNKKSYQQHRIRCHANNGPVKCQFCGKESVNASALQSHIHLHHAERPEYPCKHCKKSFKTSLRLREHEATHTGTVLYRCPWCPRTFACGSNMYKHKKAGHPIEWAASVNKRFGER
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -