Akol011279.1
Basic Information
- Insect
- Anopheles koliensis
- Gene Symbol
- -
- Assembly
- GCA_000956275.1
- Location
- JXXB01029599.1:310-3361[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.0011 0.094 13.2 5.1 2 23 57 78 56 79 0.94 2 12 1.8e-05 0.0015 18.9 5.3 1 23 85 107 85 107 0.98 3 12 2e-05 0.0017 18.7 0.4 2 23 182 203 181 203 0.98 4 12 0.047 4 8.1 11.3 2 23 238 259 238 260 0.95 5 12 0.017 1.5 9.4 7.6 1 23 266 288 266 289 0.95 6 12 4.1e-05 0.0035 17.7 0.8 1 23 372 394 372 394 0.98 7 12 0.00026 0.022 15.2 0.4 2 23 426 447 425 447 0.96 8 12 0.084 7.1 7.3 3.2 2 23 698 719 697 720 0.94 9 12 0.0018 0.15 12.6 5.8 1 23 726 749 726 749 0.96 10 12 0.00066 0.056 13.9 0.4 1 23 765 788 765 788 0.96 11 12 0.00024 0.02 15.3 1.5 1 23 794 816 794 816 0.96 12 12 0.031 2.6 8.7 2.6 1 20 825 844 825 846 0.89
Sequence Information
- Coding Sequence
- ATGTTTGACAACGAGCTGCTCTTCCACGAGCACATGCGCTCCCATCAGCGGGCTGCTGGTATGcgtgtgggtggtggtggtggtggtggtaccaCTGCCGGCGGCATTGGTTACGTCTCACCGTCGCCACCGACCCGCCGCCGTCGGACGGCCGGTCGCAGCATCATCCAGTGCGAGCTTTGCAAAAAGACGTTCATGTACCGCAGCCAGTTGCACCAGCACACGATGCTGCACCATCAGCCGGGCAAGCCGTACGAGTGCAAAATCTGCCACTACAGCTTCGTGCACAAGCTGAACCTGAAGCGGCACGAGCTAACGCATTTGCGGGAACCGCCACGACCGCAGCAGCCGGATCAGGAGCACGATGCCGACCACGATCAGCTGGACAATTCGCATCTGCTTCAGCCTTTGGTGTTGCTAGACGGACCGGAGGATGAatcgaacggtggtggtggtggtggtggagcaggTGGCGGTGACGGTCAGGACAATGGTATTGGGGGCGAGTCGAGTGCCGGTCGGGGTTGGGGGCAGAAGAAATCGAAGTGCGTCGTCTGTTCGATGATGTTCTCGAGCCAGAGCGAGCTGGTGTTGCATCTGCGGACACACATCGAGCGTATTAACGAGGCGAAGAGTGGTGGCCGAAACGCGACGATGCCGAGTGCTCCATCGACACCGAACGCGGACAGCGTGATCACACCGTCCGATCGGCAGTGCAAGCTGTGCCACAAGGTGTTCAAGTTCAGCTGCCAGCTAAAACAGCACCATCTGTTGCATCACGCGCGCGAAAAACCGTTCGAGTGTCGCACCTGTCACTATCGGTTCGAGTTCAAGGGGCATCTGGTGCGACACCGGGCGAATCATCATCCGAACGAGGACAAGGACgacaatggtggtggtggtggtggtggtagtggcaaTAGCagtatgatgatgatggacgcATCGAACCCGTTCATGACGTCGACACCGctgcgcggtggtggtgcgggaaCATCCGGTAGCAGTGTGCCAAAGTACGGTGGCCTGGTGACGGACGACGTTATTATTGCGCCGACCACATCGTCACCGCGCGGCTCGGAGAGTGGCGGCTCGGGTCCGGGTGTGCCCACGCACCAGTGTCCGATGTGTTCGCTCAAGTTCATCAAGGCACGCTCGTTGGCGATGCACATGCGGATACATCTCGGCGGGCGGAAGCTGCGGCGCGTGATACCGGCCTCCGCGGCCGATCCGGCATCGCCCTCGGAAATGCTGATGGGGGGCGCCGATAAGCTCGTGTGTCGCATCTGCGCCGGCACGTTCCCGACGGCGCACGAACTGAAAACGCACATGATGACGCACATCGGCTCGGAGCAGATGGATCTGGAGGTTCCGTTCGGGATCAGTGCGTTTAACATGCTGCACGAGAACATGTTCAACGAttcgatgggtggtggtggtggtggtgccggcggtaatggcggtggcggtggagaagGATCGTCGGGTGCGGGTGGAGAGGATCACAGCAGCATGggcggtggtgaaggtggtagCAATAGTCGTGGAGGAGAGGGAGGCGGTGGCAGTACGGACGGtgactaccaccaccaccacgatggcGAGGATGGCAGCGGTGGTGATCCGCTGTTCGATGGCTCGAACCTGGAGCTCGTGCTGAATGATAATATTCTCGATAAAGATTTCGCGATGCGAtatcagcagcagaagcgccGCTCATCGCGCCCCGGCCAcaacggtgacggtggagcGGAGGGAGCCGGTGATGGTGACGAGGGTGGAGAGGACGAAGACGATGAGGATGAAAACGAGGACGATATCACCGACACGAACGATGGCGaaatgggtggtggtggtggtggaggtggtgcggACGGCGAGGAagacgatgaagacgacgaggaggatgaggacgaaGGGGATGCGGGTTCGTCCGCGTCGACGATGGCCAGCTTCCAGCGCAACATGAACCTGATGGCGACGCACCGGTCGCGGCTTGCGGCGACGGCCGCGCTCTCCGCAGCCCGGCTACAGGCGGCCACaccgtcctcctcctcgcagTCGTCCACGTCGGGCGCGAAGGGCAAGATCGTTTGCGAGCTGTGCAAGAAGGAGTTCCTCTACCCGTGCAATCTCAACCAGCACAAGCAGCTGCACCACTCGAAGGACAAACCGCACGAGTGTCGCGTCTGCCACTATCGGTTCGAGTACGTCGGTCACCTGCAGCGGCAcatccggcagcagcacgaaTCGATGGCGGAGGAGCTGCTGGCACCGGCCGAACCGCAAACCTTCGACTGCAACTTCTGCGGCGAATCGTTCGAGGCAAAGCCTCTACTGACGGCGCACGTACACACGATGCACCGCGGCGAAAAGCCGTTCCAGTGCGACAAGTGTCCAGCAACGTTTAGCTATAAGAAATCGTACGAAACTCACCGAGAGGAACATTATTTGAAAGCCAGTAATGGAGCCTTCAAGTGTAGCTTCTGCAAGAAAACCTTCAACAGTGCACAAAAAGTAGACAACCATGTTTGCATTCAATAG
- Protein Sequence
- MFDNELLFHEHMRSHQRAAGMRVGGGGGGGTTAGGIGYVSPSPPTRRRRTAGRSIIQCELCKKTFMYRSQLHQHTMLHHQPGKPYECKICHYSFVHKLNLKRHELTHLREPPRPQQPDQEHDADHDQLDNSHLLQPLVLLDGPEDESNGGGGGGGAGGGDGQDNGIGGESSAGRGWGQKKSKCVVCSMMFSSQSELVLHLRTHIERINEAKSGGRNATMPSAPSTPNADSVITPSDRQCKLCHKVFKFSCQLKQHHLLHHAREKPFECRTCHYRFEFKGHLVRHRANHHPNEDKDDNGGGGGGGSGNSSMMMMDASNPFMTSTPLRGGGAGTSGSSVPKYGGLVTDDVIIAPTTSSPRGSESGGSGPGVPTHQCPMCSLKFIKARSLAMHMRIHLGGRKLRRVIPASAADPASPSEMLMGGADKLVCRICAGTFPTAHELKTHMMTHIGSEQMDLEVPFGISAFNMLHENMFNDSMGGGGGGAGGNGGGGGEGSSGAGGEDHSSMGGGEGGSNSRGGEGGGGSTDGDYHHHHDGEDGSGGDPLFDGSNLELVLNDNILDKDFAMRYQQQKRRSSRPGHNGDGGAEGAGDGDEGGEDEDDEDENEDDITDTNDGEMGGGGGGGGADGEEDDEDDEEDEDEGDAGSSASTMASFQRNMNLMATHRSRLAATAALSAARLQAATPSSSSQSSTSGAKGKIVCELCKKEFLYPCNLNQHKQLHHSKDKPHECRVCHYRFEYVGHLQRHIRQQHESMAEELLAPAEPQTFDCNFCGESFEAKPLLTAHVHTMHRGEKPFQCDKCPATFSYKKSYETHREEHYLKASNGAFKCSFCKKTFNSAQKVDNHVCIQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -