Basic Information

Insect: Anopheles koliensis
Gene Symbol: zfh1
Assembly: GCA_000956275.1
Location: JXXB01012529.1:15078-17037[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 3.7 3.1e+02 2.1 1.5 3 23 140 161 139 161 0.94

2 14 0.011 0.95 10.0 0.8 1 19 171 189 171 191 0.96

3 14 4.6e-05 0.0039 17.6 0.9 1 21 199 219 199 220 0.94

4 14 0.4 34 5.2 0.7 2 23 268 290 267 290 0.88

5 14 3e-06 0.00025 21.3 1.6 1 21 303 323 303 324 0.94

6 14 0.0094 0.8 10.3 1.5 1 21 332 352 332 357 0.93

7 14 0.59 50 4.6 2.3 3 23 390 412 389 412 0.88

8 14 0.0003 0.025 15.0 0.4 1 20 428 447 428 449 0.94

9 14 0.00071 0.061 13.8 1.1 2 23 457 479 457 479 0.93

10 14 2.8e-07 2.4e-05 24.5 3.0 1 23 486 508 486 508 0.99

11 14 0.0098 0.83 10.2 2.2 3 23 516 537 514 537 0.95

12 14 0.026 2.2 8.9 1.4 1 23 544 566 544 566 0.97

13 14 0.0034 0.29 11.7 2.4 1 23 572 596 572 596 0.95

14 14 0.0049 0.41 11.2 1.6 1 22 602 623 602 627 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	3.7	3.1e+02	2.1	1.5	3	23	140	161	139	161	0.94
2	14	0.011	0.95	10.0	0.8	1	19	171	189	171	191	0.96
3	14	4.6e-05	0.0039	17.6	0.9	1	21	199	219	199	220	0.94
4	14	0.4	34	5.2	0.7	2	23	268	290	267	290	0.88
5	14	3e-06	0.00025	21.3	1.6	1	21	303	323	303	324	0.94
6	14	0.0094	0.8	10.3	1.5	1	21	332	352	332	357	0.93
7	14	0.59	50	4.6	2.3	3	23	390	412	389	412	0.88
8	14	0.0003	0.025	15.0	0.4	1	20	428	447	428	449	0.94
9	14	0.00071	0.061	13.8	1.1	2	23	457	479	457	479	0.93
10	14	2.8e-07	2.4e-05	24.5	3.0	1	23	486	508	486	508	0.99
11	14	0.0098	0.83	10.2	2.2	3	23	516	537	514	537	0.95
12	14	0.026	2.2	8.9	1.4	1	23	544	566	544	566	0.97
13	14	0.0034	0.29	11.7	2.4	1	23	572	596	572	596	0.95
14	14	0.0049	0.41	11.2	1.6	1	22	602	623	602	627	0.93

Sequence Information

Coding Sequence: ATGTTATGTGATTCATTTTCGAATAAATCGTTTCCCACCGTTGCCGATGCACTCGCGCAATTTGCAAATATCAAGcTGGATGAAGCGTCCGAGGGTTTCATATGTTTAGACGAATGTTACCAACAATTAAGCATTGGGCTAGAGTTTCAAGAGTCGGTAAGGAACGTGTTTGGTCACACTACGATAGCATTACACGCAAGTCCGGATCTAAAGCCAGCAGAGACAGTGGATGCTATTGTCTGGGATGAATCGCTATCGGATTGTATCCAAATTACGCCGGACAGCATTGATGAGCACTCATCAACCTACGAATCCAACAACATTTTAGGAAGACCTTTTATGTTGCCGGCGCAAGATTTGATTGGCACGCACCTGAAGTTCGAAAACCTGGAGTACGTGGAACTGAACGGCTTACTGTGCTGTGGCTGTGACGCCATAGCGCAAAACGAAGACGAGCTAAAGTCCCACGTTTCAAAGTGCCACATAAAAGAAGACGATTCATGCGGGTTATACATGTGCAACATTTGCTATCAGTTTTTTCCCGACGCTCGTCAGCTATGTTTGCATAACGAATGGTTCCAAGCGTCGGAAGTTTTCTTCTGTAAGCTCTGCTCATACGGATTTACGTCGAAGTCGAACCTGATGCTACATATGGAAAGATGTGTCGGACAGATGCAAAGTGCGACCGAAGGCTCAACGGATCAGAATGAGAAAGAAGACGTTTGGAAAATACTGGATGATCGTCTCGTAAAGGAGCAGGAAGATTATGACGAGTACAGTATCCTACGCACGGATGCGACACGATGTTGTGCCTGTAACAAATTCTTTGCCAGTGACGAAGAAATGACACAGCACGCAGCATTGGTGCACAAGAGGCCGAATTCCGAAGAGCAAAATAACGATGATTTCTACTGTAAGGTGTGTGGAGAGACCTTCCGTAGTAGCAGTGAATTGAAACAACATCACTCTACTAAGGGCAAGACGGCACTCGTGTACTACTGCCAGCTGTGCGAGTTGCACTTTATTCGTGTCGATCAACTCGCACGACACTTTCAACGTTCCCTGAAGCATGCTTCGGCAGGGGTAAAACATCGCGATCCAACCCTAAGCGCTGCCTTAAAACTTCAACAAACTGAAAAGCCGAACCGTCCACCCGGATACGGGTGCTGCTTTGTTCGCTGCAACGCAACGTTTGAGCAGGAAACGGATCTCCACAGCCATGTTCAAGAGCTGCACGCCGTGCGCCAAGGGATTCATAAAAGAGAGCGCAAGTCCGATCAACACGTATGCGCGATTTGTCAGATGAGCTTCAACAACGAGCGCACCCTTCAGCGGCACCAGGATAACTGGCAGCTTAAGCAGGACAACGTATGTTGCCAGTGCGGGAAAGGCTTCACCAGCGGTAGTGCGCTTCGCCAGCACGAACAACTGCAGCACACAGACACGAAACTACAGTTCCAGTGCGACATTTGTGGGAAGCATTTCAAGAAGAAATCGCTCCTGAAACTACATCTCATCACACACCAGACGCTTCGCCGGTTCGGGTGCGATGAGTGTGATGCACGCTTCCATTTCGGCTATCACCTAAAACGCCACCAGCAGGCCGTACACAGGACGGACAGCTTTCCCTACGAATGCGAACATTGCGGGCGGAAAATGCCGGACAAGATGCGCTACGATCAGCACGTGCGAATGCACACCGGAGAAAAACCGTACGCGTGTCGATATGAGTGTGGTCGGACGTATTCTCACACAAGTGATCGACGCAGGCACGAGATGATGTCCCACACGGGAGAGAAACCGCATCGGTGCAGTGTTTGCAGTGTGACGTACGTGCGCCGAAGggagctgcagctgcactATCAAAAGTATCCCACTCATTCCCGGACGGAGTAG
Protein Sequence: MLCDSFSNKSFPTVADALAQFANIKLDEASEGFICLDECYQQLSIGLEFQESVRNVFGHTTIALHASPDLKPAETVDAIVWDESLSDCIQITPDSIDEHSSTYESNNILGRPFMLPAQDLIGTHLKFENLEYVELNGLLCCGCDAIAQNEDELKSHVSKCHIKEDDSCGLYMCNICYQFFPDARQLCLHNEWFQASEVFFCKLCSYGFTSKSNLMLHMERCVGQMQSATEGSTDQNEKEDVWKILDDRLVKEQEDYDEYSILRTDATRCCACNKFFASDEEMTQHAALVHKRPNSEEQNNDDFYCKVCGETFRSSSELKQHHSTKGKTALVYYCQLCELHFIRVDQLARHFQRSLKHASAGVKHRDPTLSAALKLQQTEKPNRPPGYGCCFVRCNATFEQETDLHSHVQELHAVRQGIHKRERKSDQHVCAICQMSFNNERTLQRHQDNWQLKQDNVCCQCGKGFTSGSALRQHEQLQHTDTKLQFQCDICGKHFKKKSLLKLHLITHQTLRRFGCDECDARFHFGYHLKRHQQAVHRTDSFPYECEHCGRKMPDKMRYDQHVRMHTGEKPYACRYECGRTYSHTSDRRRHEMMSHTGEKPHRCSVCSVTYVRRRELQLHYQKYPTHSRTE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00100505;
90% Identity: iTF_00100505;
80% Identity: -