Basic Information

Insect: Anopheles koliensis
Gene Symbol: wdn
Assembly: GCA_000956275.1
Location: JXXB01033980.1:179-2258[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.0059 0.5 10.9 2.4 2 22 101 121 100 121 0.95

2 10 0.0072 0.61 10.6 1.2 1 23 129 151 129 151 0.95

3 10 8.1e-08 6.9e-06 26.2 4.2 1 23 159 181 159 181 0.99

4 10 0.00034 0.029 14.8 0.8 1 23 206 229 206 229 0.98

5 10 0.0021 0.18 12.3 0.1 2 23 237 257 236 257 0.94

6 10 9e-07 7.7e-05 22.9 1.0 1 23 263 285 263 285 0.97

7 10 3.7e-06 0.00032 21.0 5.7 1 23 291 313 291 313 0.98

8 10 0.00033 0.028 14.9 4.4 1 23 319 341 319 341 0.96

9 10 0.00012 0.01 16.2 0.5 1 23 347 369 347 369 0.97

10 10 5e-05 0.0042 17.4 3.0 1 23 375 398 375 398 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.0059	0.5	10.9	2.4	2	22	101	121	100	121	0.95
2	10	0.0072	0.61	10.6	1.2	1	23	129	151	129	151	0.95
3	10	8.1e-08	6.9e-06	26.2	4.2	1	23	159	181	159	181	0.99
4	10	0.00034	0.029	14.8	0.8	1	23	206	229	206	229	0.98
5	10	0.0021	0.18	12.3	0.1	2	23	237	257	236	257	0.94
6	10	9e-07	7.7e-05	22.9	1.0	1	23	263	285	263	285	0.97
7	10	3.7e-06	0.00032	21.0	5.7	1	23	291	313	291	313	0.98
8	10	0.00033	0.028	14.9	4.4	1	23	319	341	319	341	0.96
9	10	0.00012	0.01	16.2	0.5	1	23	347	369	347	369	0.97
10	10	5e-05	0.0042	17.4	3.0	1	23	375	398	375	398	0.98

Sequence Information

Coding Sequence: ATGGATTATACACAAACATTCTTACCGAACGTAATCCTGGAAGGTTTTGGCGAACGAAAGCATCCTGATGGAGTTAAAATTGAGCTGGATGACAGGATTGTTGGCGGTACTAAAAGTAAAAAGGATCGTATTGGGAATGAATTGAAGCTTGTCATGGAACCGCAAAATCCGTCTCCAACAAAGTATTTCGACAACAATGGCGTACCATTGCGTAAGGCTCTGGAAGAAGGGAACGCTGTGCTACCCGAAACGGATtcgtttgatgatgaaaagaaatcgaaaggaaacaaaatcaacctAAAATGCTGCAACTGTGCAAAAACGTTTACATCCCGCGCCACGTATGAACTGCATTACCGCACGGCATACCAGCAAGATCCGGTGTATGTTTGTACCGTGTGCGGCAAGCGAATAAAGCAGTACCGAGCATACCAGTTGCACAGCTACCGGCACAAAAACAGTGCCAACCAGCGATTCACCTGCCCGGATTGTTCCAAAACGTTCCATCAAAAGTCCGATCTCACTCGTCACCAAAACACGCATGTGCTCGGTAGCAGTTCGGGTTCATCGAAGGATCGTAACATGAAGACAGTTGATGTGCCGTTATCATTGAGATACTCTTGCGCGAGATGTGACGCCACGTTCGAAACGCAAACCGAGATGAAGGAACACACTCGAAAGCTGCATCGTACACCAAAACAGCTAGTTGAGTGTCCAGATTGTGGAAAATCTCTCTCGACAGGCAGCCTTTATTCCCACCGCAAGATACACTCGGAAAGCCCAAAGTTTGCGTGCACTGAATGTGGTCGCGCATTCGTGCAGAAGATCAATCTGATTCAACACCACAAAACGCACCTCAGCGAGCGGCCGTTCCAGTGTGAGCAGTGTGATAAATCGTTCTGCGAGAAGGCGCATTTACAGCGTCATTTAAACTATCACTCGCAGGAGCGTCCTTATCGCTGTGATTTGTGCGGAAAGTGCTACAAAACGGAACGCTGTTTGAAGGTACATTCGGCCGTGCACAATAACGAGCGCCCGTTCGTGTGCCCCGAGTGTAATAAAGGGTTCCTGAGCAGTTCCAAGCTGCGCCAGCACAGCAACATTCACTCCGGACTGCGGCCGTTCAAGTGCAAATATTGTACGCGTGATTTCACCAACTTTCCGAACTGGCTCAAGCATATTCGTCGCCGACACAAGGTGGATCATCGCACGGGCGAGAAACTGGATAGTGTGCCAAAGTTTATGACGAAGAAAAAGGTCCCCAgtggggatggtggtggtagcggcaGGAAGAATGGAAACACGGAAGACgcggtggaaaaaacaaaaaagcgaacaccGAAACAGCTCGCTTTGCCGGACGTGCTGAAGGACGAGTCACTACCGTACTTCAGCGAAAGCTCCAACATTGATCTCAATCTAGTTTGTAAGGACGATCTGCTGCAGCCGCTGACGGATGAGATGGAAGACATCTTCCAGTGCCTACCGTCCGACGAGTCAAAGCTGAGCATTCCGGAGCCACTGTGCAGCAGCTCCAATGCAGCCGGCGAAGACGAGGACGGGTTATTAAATGGAAGCTTACTCCCACCGGCGGTGGATTGTGATTTTAGCGTTAAAAATGACTCAATCGATCTCATTAAACATGAACTCCCGAGTCATGCACTGGCGGACTGTGCGGAGGAAGCACTAGCCGGACCTCTGCTGTACGATGCACAGCTACCCGCTATGTTTCCAGCGATGGTGTCATTTCGCAACGATGAGCAACAGTTTCGGCTGATCAATCCGCATTGCATACATCTGAGCAGTACCGCAGCTCTACTCGCCACTGGAAGCTCCAAACTATCGCCGGACAATGGTTCCGTGCCGGTTTCAATCAGCGATTGA
Protein Sequence: MDYTQTFLPNVILEGFGERKHPDGVKIELDDRIVGGTKSKKDRIGNELKLVMEPQNPSPTKYFDNNGVPLRKALEEGNAVLPETDSFDDEKKSKGNKINLKCCNCAKTFTSRATYELHYRTAYQQDPVYVCTVCGKRIKQYRAYQLHSYRHKNSANQRFTCPDCSKTFHQKSDLTRHQNTHVLGSSSGSSKDRNMKTVDVPLSLRYSCARCDATFETQTEMKEHTRKLHRTPKQLVECPDCGKSLSTGSLYSHRKIHSESPKFACTECGRAFVQKINLIQHHKTHLSERPFQCEQCDKSFCEKAHLQRHLNYHSQERPYRCDLCGKCYKTERCLKVHSAVHNNERPFVCPECNKGFLSSSKLRQHSNIHSGLRPFKCKYCTRDFTNFPNWLKHIRRRHKVDHRTGEKLDSVPKFMTKKKVPSGDGGGSGRKNGNTEDAVEKTKKRTPKQLALPDVLKDESLPYFSESSNIDLNLVCKDDLLQPLTDEMEDIFQCLPSDESKLSIPEPLCSSSNAAGEDEDGLLNGSLLPPAVDCDFSVKNDSIDLIKHELPSHALADCAEEALAGPLLYDAQLPAMFPAMVSFRNDEQQFRLINPHCIHLSSTAALLATGSSKLSPDNGSVPVSISD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00100468;
90% Identity: iTF_00100468;
80% Identity: -