Basic Information

Insect: Anopheles koliensis
Gene Symbol: Ctcfl
Assembly: GCA_000956275.1
Location: JXXB01038342.1:3406-6108[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.00063 0.054 14.0 3.0 1 23 160 182 160 182 0.98

2 11 3.2e-05 0.0027 18.1 1.0 1 23 188 210 188 210 0.98

3 11 3.7e-05 0.0032 17.8 7.4 1 23 216 239 216 239 0.97

4 11 3.3e-05 0.0028 18.0 1.8 1 23 245 267 245 267 0.98

5 11 9.7e-06 0.00083 19.7 2.2 1 23 273 295 273 295 0.99

6 11 8.5e-05 0.0073 16.7 0.7 1 23 301 323 301 323 0.98

7 11 0.0005 0.043 14.3 1.8 1 23 331 354 331 354 0.96

8 11 0.0018 0.15 12.5 2.4 2 23 361 382 360 382 0.97

9 11 0.0081 0.69 10.5 0.8 1 23 388 410 388 410 0.97

10 11 1.8e-05 0.0016 18.8 2.6 1 23 416 439 416 439 0.97

11 11 5.2e-07 4.5e-05 23.7 2.6 3 23 455 475 453 475 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.00063	0.054	14.0	3.0	1	23	160	182	160	182	0.98
2	11	3.2e-05	0.0027	18.1	1.0	1	23	188	210	188	210	0.98
3	11	3.7e-05	0.0032	17.8	7.4	1	23	216	239	216	239	0.97
4	11	3.3e-05	0.0028	18.0	1.8	1	23	245	267	245	267	0.98
5	11	9.7e-06	0.00083	19.7	2.2	1	23	273	295	273	295	0.99
6	11	8.5e-05	0.0073	16.7	0.7	1	23	301	323	301	323	0.98
7	11	0.0005	0.043	14.3	1.8	1	23	331	354	331	354	0.96
8	11	0.0018	0.15	12.5	2.4	2	23	361	382	360	382	0.97
9	11	0.0081	0.69	10.5	0.8	1	23	388	410	388	410	0.97
10	11	1.8e-05	0.0016	18.8	2.6	1	23	416	439	416	439	0.97
11	11	5.2e-07	4.5e-05	23.7	2.6	3	23	455	475	453	475	0.94

Sequence Information

Coding Sequence: ATGAGCGCTAGACGAGCGAAACAGCAggaggtgaaaacaaaaaaggtccAACCGGAACTGGTGGAGGCTCCGCTGAAGGTGGCGAAGCAGGAGAAGCTGGACATCGACGAGATGGAGCTGATGACGGCGGGTTtggatgacgacgaggaaggTGGTTGCTATTTTGTCGACCAGAAGGGAAACTACTACTTTCAGGCCAGCGAGGACGCGGAACTGACCGCGGTAGAGAACGGTGAAGCCGAATTCGATTTGATGGATGTGCCGCAGAAGAATGACGAGGAGGAGGTAAACTATGTACTGATTACGAACGAGGGTGGCAACAAAACGATGGTGGTCAACAACGACGGTACCGAGATGGGTGAGACAAAGGACAACGAGATTTACGATTTCGACGATCCGGACTACATCGTGCAGGAGCAGGACGCGAAGGGTCAGCAACCACGAGTAAAACGGGGCCAATCGAGTGCCGGATCCACGTACATGTGCAATTACTGCAACTACACCAGCAACAAGCTGTTTCTGCTGTCACGGCATCTGAAAACTCACTCGGACGATCGGCCCCACaagtgtgtggtgtgcgagCGTGGATTTAAAACGCTGGCCTCGCTGCAAAATCACGTCAACACGCACACTGGCACGAAACCACACCGGTGTAAGCACTGTGACAATTGTTTTACTACTTCCGGTGAGCTGATACGTCATATCCGGTACAGGCATACGCACGAACGGCCCCACAAGTGTACGGAGTGTGATTACGCAAGTGTGGAGCTGAGCAAGCTAAAGCGCCACATTCGTACGCACACGGGCGAAAAACCGTTCCAGTGTCCGCACTGTACGTACGCATCGCCGGATAAGTTTAAATTGACGCGCCATATGCGCATTCACACCGGTGAAAAACCGTACTCGTGTGACGTTTGTTTCGCCCGGTTCACGCAGTCGAATTCGTTGAAGGCTCACAAAATGATTCACCAAGTTGGCAACAAGCCCGTTTTCCAGTGTAAGCTCTGCCCCACAACGTGCGGCCGCAAGACCGATCTGCGTATTCACGTGCAGAATCTGCACACGGCGGACAAGCCGATCAAGTGTAAGCGCTGTGAAAGCACGTTCACCGATCGCTACAGCTACAAAATGCACGCCAAAACGCACGAGGGCGAAAAGTGCTACCGGTGTGACTTCTGCCCGTACGCCTCGATCTCAATGCGGCACCTCGAGtcgcatctgctgctgcacaccgATCAAAAACCGTACAAGTGTGACCAATGTGCGCAAACCTTCCGCCAGAAGCAGCTGCTAAAGCGGCACATCAACTACTACCACAATCCGGACTACGTCGCTCCGACACCGAAAGCAAAGACGCATCTCTGTCCGACCTGTGGTCGTACCTTCCGGCACAAGGGCAACCTGATACGGCACATGGCACTGCACGATCCCGACTCGTCCGTGCacgacgagctgctggcgTTGCGCGAAGGCCGCCAGAAGAAGGTGCGCATCATactggaggaggaagagtACAAGGGCGAGGAGGACTATGATGAGGAGGAAATGGAAgacgaggaggatgaggaagCGGACGAGGACCAGGAAGCGGTGACAGGGGAGGAAGATGAGTTGGAAATGTCGCGGATGCAAACGAGCGACATGGTTACGGTGGAGGACGACGATGGTCAGTACGTTGTGCTGGAGGTGATACAGCTGCAGGATAAGGATATCGATAAAAGTACCGGTGGAGCAAAACCCAAAGGAAAGCGAACAgggacgaaacggaaagcCGTTACTGCGGCAGCAACGACCTCTAAGCCtgctacgacgacgacgacgacaacgactaCCAGCGCTTTATCGGCAACAGCAACGCGTATGCAGAAGGCGTTGAAAAAGCAACTACAGCAAATTTCCGACGATCCACAAACGTTGGATGCGGACGAAATCCATCTAGCACTGGCAgatggggaaggggaaaatgACGCACAAGAGATAGTCATCGAGCAAAGCCCCGAGTCGGAGGATGAGTTTCTGCTCTCGACGGaagATTTACAAGACACGGAAATGCTGATGTCATCGCtgcaaaatacaaaacgtCCGCGCTTTGCTGTTACCATTAGCCAGGAAGATTTGGAGAAAAACATGAGCAACTGCTTCGGATTCGATgacgatgaggacgaggatCTGGATACCAAAGCAACGATTACGCTGCTCAACTAA
Protein Sequence: MSARRAKQQEVKTKKVQPELVEAPLKVAKQEKLDIDEMELMTAGLDDDEEGGCYFVDQKGNYYFQASEDAELTAVENGEAEFDLMDVPQKNDEEEVNYVLITNEGGNKTMVVNNDGTEMGETKDNEIYDFDDPDYIVQEQDAKGQQPRVKRGQSSAGSTYMCNYCNYTSNKLFLLSRHLKTHSDDRPHKCVVCERGFKTLASLQNHVNTHTGTKPHRCKHCDNCFTTSGELIRHIRYRHTHERPHKCTECDYASVELSKLKRHIRTHTGEKPFQCPHCTYASPDKFKLTRHMRIHTGEKPYSCDVCFARFTQSNSLKAHKMIHQVGNKPVFQCKLCPTTCGRKTDLRIHVQNLHTADKPIKCKRCESTFTDRYSYKMHAKTHEGEKCYRCDFCPYASISMRHLESHLLLHTDQKPYKCDQCAQTFRQKQLLKRHINYYHNPDYVAPTPKAKTHLCPTCGRTFRHKGNLIRHMALHDPDSSVHDELLALREGRQKKVRIILEEEEYKGEEDYDEEEMEDEEDEEADEDQEAVTGEEDELEMSRMQTSDMVTVEDDDGQYVVLEVIQLQDKDIDKSTGGAKPKGKRTGTKRKAVTAAATTSKPATTTTTTTTTSALSATATRMQKALKKQLQQISDDPQTLDADEIHLALADGEGENDAQEIVIEQSPESEDEFLLSTEDLQDTEMLMSSLQNTKRPRFAVTISQEDLEKNMSNCFGFDDDEDEDLDTKATITLLN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00100461; iTF_00099151;
90% Identity: iTF_00100461;
80% Identity: -