Basic Information

Insect: Anopheles koliensis
Gene Symbol: -
Assembly: GCA_000956275.1
Location: JXXB01013021.1:3311-5277[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.00024 0.021 15.3 0.6 1 23 241 263 241 263 0.98

2 11 0.022 1.9 9.1 0.2 1 22 267 288 267 291 0.91

3 11 0.5 42 4.9 0.0 1 21 332 352 332 355 0.83

4 11 8.2e-05 0.007 16.8 0.7 1 23 362 384 362 384 0.96

5 11 2.3e-05 0.0019 18.5 2.9 1 23 390 412 390 412 0.98

6 11 0.00017 0.014 15.8 1.1 1 23 418 440 418 440 0.98

7 11 1.8e-07 1.5e-05 25.1 1.1 1 23 446 468 446 468 0.98

8 11 0.0054 0.46 11.0 2.1 1 23 474 496 474 496 0.98

9 11 4.5e-06 0.00038 20.7 0.8 1 23 502 524 502 524 0.98

10 11 7.7e-07 6.5e-05 23.1 0.2 1 23 530 552 530 552 0.99

11 11 1.7e-06 0.00014 22.1 0.4 1 23 558 581 558 581 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.00024	0.021	15.3	0.6	1	23	241	263	241	263	0.98
2	11	0.022	1.9	9.1	0.2	1	22	267	288	267	291	0.91
3	11	0.5	42	4.9	0.0	1	21	332	352	332	355	0.83
4	11	8.2e-05	0.007	16.8	0.7	1	23	362	384	362	384	0.96
5	11	2.3e-05	0.0019	18.5	2.9	1	23	390	412	390	412	0.98
6	11	0.00017	0.014	15.8	1.1	1	23	418	440	418	440	0.98
7	11	1.8e-07	1.5e-05	25.1	1.1	1	23	446	468	446	468	0.98
8	11	0.0054	0.46	11.0	2.1	1	23	474	496	474	496	0.98
9	11	4.5e-06	0.00038	20.7	0.8	1	23	502	524	502	524	0.98
10	11	7.7e-07	6.5e-05	23.1	0.2	1	23	530	552	530	552	0.99
11	11	1.7e-06	0.00014	22.1	0.4	1	23	558	581	558	581	0.94

Sequence Information

Coding Sequence: ATGTCCAGTTTCACGGTAGACCCGAATTTGGAGCCAAAACCTTTGCTTTACGACTCAAAAGTGTGCCGGTTGTGtggagaacgaaacgaaaatggacGCCCGTTATACCGGGATTGCGTTGAAGGTGGTGAATGTGAAGTAAGCAAGCTAATTAATCAGTACCTACCGGTGAAGGTGGTTGATGATGGTGTCCTTCCGCGATGGATCTGTCCCGGGTGTCACATCCAACTGGAATCAACGGCACAATTCTTCGAAATGATACTAAAGGGTCAAGAGCAGTTAGCAACCATGAGggaaaagcagcaaacgctCAGCAAAGCCTTGCGCGTAGACGATCAGTTGCAGCTGTACGATATTATGGATCCGGATAAATGGAACGAGTTGTTCGAAAAGCCCGACTTAATCACCTCTGGAGATAAGGAAAACCTGCTTGTGCCGATCGAATTGTTCGAACTGGAGGATTTACTCAAACCGATCGAGAGTGTTCCGGATCAACCCGAACCGAGCGCTCCGGAATCGGTAGAAACACCAGCTAAACAGCCGGAACGGACCGATGAATTGGAGAAGGATGAAGGAACGGACTGGGTTGTCAAATCGGAAGTAACCGTGGCATCCGGTGGACGTGTGATCGGTTTCGTgcaccacaacaacagcaaaaccgaCATCGgcaagctggtggtggtggatgacGCATCGGGGCGGAAGAAAATTGGTCCGAAATTCGTGTGCGATATCTGCAGTGAAAGTTTTGCACGCGAACCACGCTACTTAAAGCACCGGAAGACGCACAGCATTCTGTTCGAGTGTTCCGTGTGTCTGCTCAAGTTCGGGTCGAATGGAAAACTGCTGGTACACCAGCAGGAAACGCTACACATTGGTAGAGGAATGGTGGAAGGTTTAAAGGTACCGGAAGAGAGTAGTTGTTCGCGGCGGAAAGGTGACTCGAAAGGGACGGTAGAAAGTGGAACCAATGCATCGGCTGGTGATAATGTGTATGCATGTGATAATTGCGATAACACGTTTGCTGGATTGGGTACGGTACTGCAGCACGAGGGTTCGGTGCACGCACAAGAAAATCATTCGTTTGTGTGCATCGACTGTGGGAAAGCGTTCCGCGAGCGGAATCTGCTGTACCGGCATCGTCAAACGCACCAGGAGGATCGAACGCACCGGTGCACAGTGTGTACGGCAGCGTTCAAAACTCGATCCACCCTCTCGAAGCATGTGCGATCACACGACGACACCAAGCGCTACCGGTGCACAATGTGCGATCAGCAGTTTGCCTACAAATCCGGATACGACAAGCACCTGAATTGGCACAACGGTGTGAAGCCGTTCGAATGTGAGCTCTGCTCGAAACGATTCTCCCAACGCGGCAACCTGAAGGAACACCAGCGGGTCCACTCGGGAGACAAACCATTTCGGTGCACGATCTGTGAGGCACGGTTCGGGACGAGTTCGCAGCACCGGGCACACGTCAAGCGACACGATGCGGCCCGCCCGTTCGTTTGCGATCTGTGCGACAAGACGTTTGTGTTGCGGGAAAACTACGAAACGCATCTGCGGCGTCACCGTAACGAAAAACCGTACTCCTGCGAGGACTGTCCACGCTCGTTCGCGGAGCGATGGGCGCTGAAAAAGCACGTGCGGACGCACACGCTGGAAAAACCGTACAGCTGTAAGCACTGTGCGAAACCGTTCGCCGATCCGTCGAATTTGACGCGCCACGTAGTGTCGGTGCATGAGAAGAAGGGTAAGGAGGTGGGCCAAAGGGCTGTAGCAAGCGCCGGTGCAGAGCCGGAACGCAGTACGATCGTGTGCGAGACAAGCAACGGTGATGCGGCCGATACAATCGAAGCAGTGACGCTGTCACTGGATGAGACGGTGTACATGGAAGGATAG
Protein Sequence: MSSFTVDPNLEPKPLLYDSKVCRLCGERNENGRPLYRDCVEGGECEVSKLINQYLPVKVVDDGVLPRWICPGCHIQLESTAQFFEMILKGQEQLATMREKQQTLSKALRVDDQLQLYDIMDPDKWNELFEKPDLITSGDKENLLVPIELFELEDLLKPIESVPDQPEPSAPESVETPAKQPERTDELEKDEGTDWVVKSEVTVASGGRVIGFVHHNNSKTDIGKLVVVDDASGRKKIGPKFVCDICSESFAREPRYLKHRKTHSILFECSVCLLKFGSNGKLLVHQQETLHIGRGMVEGLKVPEESSCSRRKGDSKGTVESGTNASAGDNVYACDNCDNTFAGLGTVLQHEGSVHAQENHSFVCIDCGKAFRERNLLYRHRQTHQEDRTHRCTVCTAAFKTRSTLSKHVRSHDDTKRYRCTMCDQQFAYKSGYDKHLNWHNGVKPFECELCSKRFSQRGNLKEHQRVHSGDKPFRCTICEARFGTSSQHRAHVKRHDAARPFVCDLCDKTFVLRENYETHLRRHRNEKPYSCEDCPRSFAERWALKKHVRTHTLEKPYSCKHCAKPFADPSNLTRHVVSVHEKKGKEVGQRAVASAGAEPERSTIVCETSNGDAADTIEAVTLSLDETVYMEG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00099147;
90% Identity: iTF_00100459;
80% Identity: -