Basic Information

Insect: Anopheles gambiae
Gene Symbol: PEG3
Assembly: GCF_000005575.2
Location: NT:22681520-22686005[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2e-05 0.001 18.9 1.7 1 23 118 140 118 140 0.97

2 15 0.0059 0.3 11.1 4.5 1 23 146 168 146 168 0.96

3 15 3.5e-05 0.0018 18.1 0.1 1 23 315 337 315 337 0.98

4 15 0.33 17 5.6 0.3 1 23 343 366 343 366 0.96

5 15 0.09 4.6 7.4 2.4 1 23 400 423 400 423 0.93

6 15 0.0022 0.11 12.5 0.0 2 23 461 482 460 482 0.94

7 15 0.0054 0.27 11.3 0.1 2 23 493 515 492 515 0.92

8 15 0.0025 0.13 12.3 0.9 2 19 523 540 522 541 0.95

9 15 0.0059 0.3 11.1 8.9 1 23 550 572 550 572 0.97

10 15 0.023 1.2 9.3 0.8 2 23 578 599 577 599 0.97

11 15 9.6e-07 4.9e-05 23.1 1.3 1 23 605 627 605 627 0.98

12 15 0.00081 0.041 13.9 0.2 1 23 633 655 633 655 0.97

13 15 2.1e-05 0.0011 18.8 0.1 1 23 661 683 661 684 0.95

14 15 0.036 1.8 8.7 0.1 1 23 698 720 698 720 0.97

15 15 1.3 66 3.8 2.3 1 20 1238 1257 1238 1260 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2e-05	0.001	18.9	1.7	1	23	118	140	118	140	0.97
2	15	0.0059	0.3	11.1	4.5	1	23	146	168	146	168	0.96
3	15	3.5e-05	0.0018	18.1	0.1	1	23	315	337	315	337	0.98
4	15	0.33	17	5.6	0.3	1	23	343	366	343	366	0.96
5	15	0.09	4.6	7.4	2.4	1	23	400	423	400	423	0.93
6	15	0.0022	0.11	12.5	0.0	2	23	461	482	460	482	0.94
7	15	0.0054	0.27	11.3	0.1	2	23	493	515	492	515	0.92
8	15	0.0025	0.13	12.3	0.9	2	19	523	540	522	541	0.95
9	15	0.0059	0.3	11.1	8.9	1	23	550	572	550	572	0.97
10	15	0.023	1.2	9.3	0.8	2	23	578	599	577	599	0.97
11	15	9.6e-07	4.9e-05	23.1	1.3	1	23	605	627	605	627	0.98
12	15	0.00081	0.041	13.9	0.2	1	23	633	655	633	655	0.97
13	15	2.1e-05	0.0011	18.8	0.1	1	23	661	683	661	684	0.95
14	15	0.036	1.8	8.7	0.1	1	23	698	720	698	720	0.97
15	15	1.3	66	3.8	2.3	1	20	1238	1257	1238	1260	0.92

Sequence Information

Coding Sequence: ACGCCGGACGGCCGGGAGTACCTCGTGGACGAACGGTCGATACAGAACATCGATCAGATACCGCCGGAAAACTTGATCTACATGACCGCTTCCGAAGCGCTGTCGGTGGTCGATGCGGATGACGTCGGCCAGCTCGCGATTGTGGACGAAAGTCAGCTCGCGCTGCACGATTACTACGCGGAAGAGTGCGAGGTGACGGAGGAAGTGATTACGGACGATTGGGTGCAGCCGCAGGGCGAAGAGTGCGTGCAGGTGACGGTCGACCAGCTCGGTGTGAGTGCGGTCGTGGTGCAGGAGGAGGACGACATTTCCGTCCCGCTCGACCAGGACCAGTACACGCTGTCGCGCCCGTACCCGTGCGATTTCTGCAGCCGGCGGTTCCGCAAGAAGAGCAGCCTGCAGAACCATCTGATGGCGCACTCGAACGATCGGCCGCACTGTTGCAACCTGTGCGGGGCACAGTACAGCCACCGGGCGGATCTGATCAACCATCTGAAGCAGCACGCCGACGACGAAGACATGTACATCCAGAACTCGATGGTGAGCTACAACTCGCAACCACCGATGCAGCTGATTTCCACCACGCATTACGGTGCTTCTTCCTCGTCGACAATCGGCTCTTCCTCGTACGTGCATGACGTACCGATGGAGCAGCCGCCTTACCTCGAGAGCGTTCCTCCCGTGCTGGAGCAAAAGTATGCGCTCGGCAAAATGGATCCGACCGGCCCGGCAACACTTTCCAACACCACCGGCAAACGTACGCCGCGGAAAAAGCAATCCCAATCTACCCAGGATACGCGAACGGCACGGACAAAGCCCGTGTTTGCCTCAAAACTCGGCAGTCGGCAGATTAAAAAGGAACCCCTGGAGCATGGGGAAGGTGGTAACGCCATATCATCGCCACCTCCCACGAGGACGGTCGCAGCGGACTGGCGCAAACCGTTCGTCTGTCAGCAGTGTGGCGCATCGTTCGCGCGAGAGAAAGCGCTCCTTTCGCACGCCCGCACCCATGCCGGCAGCACGCGCTACGATTGCGCACTGTGCAATGCGCATTTTTGGGAGCAGTCGCTGCTGCGGGATCACGTGCAGCGAGCGCACCAGGCGCAGGAAGCTTGGGTGGCCGACCACGAGCCTTACGGCAGTGCGCACGGAGCGATAGAGCTGCCGGTggtgaccaccaccaccaccaccaagcagTACAATTGTGATAGCTGCAGTGCAGTTTTCTTCCAGCTGGACCATCTACTGAATCATACGCACCAAGCGCACGGCACCTTCGAGCAGCATCAGCAATCGAGCTCGAACCGTAGTGTGCTGGTGAAGCAGGAACTGCTGCAAACCTCCAGCAAAcgtTCGAACGAACCCGACCAGTCCGCGCTGACGTGTCGCGATTGTGGGGAGTCGTTCGACAGCGCGATGGACTTGCTCGACCACAGTGAGGTGCACGGTGGTGGCGCCGCCCAGTACGAACCGCTCGAGTGTCAGCTGTGCGGGGAGAAGTTCCCGGACGAGGCCAACATCAAGCAGCACGTGCAGGACCGGCACCGGGACGAGCTGACCGCAACGTCGTGCGCGATCTGCGGCAAGCGCTGCAAAAGCCAAACCACGCTGATGAAGCACGCGTGGGACCATTCGCGCGAGCGGGCCCACTCCTGCTCGAAGTGTGGCAAAACGTTCCACCACATGACGCGGCTGAAGCGGCACATGGACTCGCACCGCAACAAGGCGGTCCGGTGTGAGGTGTGCAAGGAAGAGTTCCCGGACGGCCGGACCCTGATGAACCATCGCCATTCGCACACGAAATCGAACGAGTATCCGTGCCACGAGTGTGGCAAAACGTTCGGTTCGCGCTCGTCGCAGCAGATCCACATGCGCATCCACACGGGGGAGCGGCCGTACGCGTGCCGGTTCTGCTGGAAAGCGTTCGCCGACGGGGGCACACTGCGCAAGCACGAGCGCATCCACACGGGGGAGAAACCGTACGCGTGCCCCGTCTGCCCGAAAGCGTTCAATCAGCGCGTGGTGCTGCGCGAACACATCCGGGCGCATCATTCGCAGGCGGACGCGAAGCGCGGCTCGCCGGACCAGCCGTACTACTGTACGGTTTGCAGCTCACCGTTCGGCACGACCGCCGATCTGGTGCAGCATCTGATCGAGCACAGTGACACGAACACGGCGATGAAGCGCAAACCGCCCACCTTCCCGCGCAAGTACAAGCGGCGCCGGAAGCTGAAACCGCACGAGCTCGAGCGGCTGCAGAGCGGCCGGCGGAAGCAGAAATCCAAGCGCCAGATGGAcaacgaggaggaggaggaggaagaggaggaggacgatgacgatgggaGTGGGGGTAGTGGGAATCAATTCGAGGACGGTACGACAGCGCGCACAACGGATCGCACGGTGGTGGAACGTGCGCGCGGCGATGGCAAACCAACCGGCTCCTCGTTCGTTCGCTACCATCCGGACGGGACGCGCAAAGCAAGCACGCGCGAAATGTACCTTGAGTATGACGACATGGGAGGAGGGAGCGTCACGCATGCCCCCAAGGCATCCTCGCAAGGTATGCTGGACGTCAATGGGATCAATCTGCTGAGCaatgttgtgctgctgcacggACAGCAGGAAGAGCCGTCCCAcgcgcacaacaacaaccatctgCCCGAATCTCCTCCCCGGCACATGTTCGGGGAGTTGCCCAAAGCGAAACAGCAGCCACCGGGAAATTCGCGCATGATTTACACCCAAAAATCAGCCACAAAAGCAGCCCCAGCGTCGTCCCGCAAAACGCCATCCGCCCGGAAACGGCCCGCCGCCAAAGAGCAGCGCCCGGCGGCagcgccaccgccgccggtgAAGCTGGAACCCGACGCGGATGATCCTGCCATCGCGATGGAAGCGTTGTTCCGCGGGCGCAAACGGAACGCTTCACTGCTGCCCGAGATCCCGCCGCACCGGATCTCGTCCGTCGGCTTCCCGCTGCTGGACGATGGCAACACGGACGACCCGCTGGACGAGCCGGAGCAGCGGGCGCGCCGCAGTACCGCCTCGTTCAGCGCCTCGGAGGACGATCTGCTCAGCCAGCAGCTGCTGATGGAGATTTCGCACAAGAGCAAGTACAGCGAGCGGTTCAACAGCGACACGCTGAACGATCTGGAGGAAATACTCCGCTCGCCCGTCAAGGGTGCCGGTTCGCCGGCACTGGCCAAACGTGCCACGACCGTTCCCTCCACCAGTGCTACCGGtaagaagcaacagcaaagtGCCGCTAAaaagccaaccagccagcgTAAGCGAACGGCAGCACCGAAAGCAAAGGCTGCGGCGAAGGCGAAGAATAAACCTGCTGCTTCCTCCACTGCCAGTGGCGCCGGTTCCTCCAACAGCAGGCAGCCACCACAAAAGCCAGTGGAAAAGCGAGCGGCCCGGGAACCGCCGGCAGTcagcagcggtgagGGAAGTCGCCGTAGCAGTGTGATGTCCACCGCAGCGCGACAGACGCATAAGTACGGTCCGGAATCGTACGCAGAAGAATTGCAGATGATGGAAACGGCGGAGGAGGAACATGTGGTAAAGCAGGAGGATGACCAGGGGCAGGGTGAACATCACTACGAGCTGGGTGACGACGATGTGGGTGAACTGTATCTGGATGATAACGACACTACTACCtcagcaacaacaccagccGCAGCCATTGGTGACGAATCGTTGCATCGATGTTCGATCTGTTGCGCCTGCTTCGATGATCGGGCACAGCTCATCCTGCACGTTCCGGTGCATATTTAG
Protein Sequence: TPDGREYLVDERSIQNIDQIPPENLIYMTASEALSVVDADDVGQLAIVDESQLALHDYYAEECEVTEEVITDDWVQPQGEECVQVTVDQLGVSAVVVQEEDDISVPLDQDQYTLSRPYPCDFCSRRFRKKSSLQNHLMAHSNDRPHCCNLCGAQYSHRADLINHLKQHADDEDMYIQNSMVSYNSQPPMQLISTTHYGASSSSTIGSSSYVHDVPMEQPPYLESVPPVLEQKYALGKMDPTGPATLSNTTGKRTPRKKQSQSTQDTRTARTKPVFASKLGSRQIKKEPLEHGEGGNAISSPPPTRTVAADWRKPFVCQQCGASFAREKALLSHARTHAGSTRYDCALCNAHFWEQSLLRDHVQRAHQAQEAWVADHEPYGSAHGAIELPVVTTTTTTKQYNCDSCSAVFFQLDHLLNHTHQAHGTFEQHQQSSSNRSVLVKQELLQTSSKRSNEPDQSALTCRDCGESFDSAMDLLDHSEVHGGGAAQYEPLECQLCGEKFPDEANIKQHVQDRHRDELTATSCAICGKRCKSQTTLMKHAWDHSRERAHSCSKCGKTFHHMTRLKRHMDSHRNKAVRCEVCKEEFPDGRTLMNHRHSHTKSNEYPCHECGKTFGSRSSQQIHMRIHTGERPYACRFCWKAFADGGTLRKHERIHTGEKPYACPVCPKAFNQRVVLREHIRAHHSQADAKRGSPDQPYYCTVCSSPFGTTADLVQHLIEHSDTNTAMKRKPPTFPRKYKRRRKLKPHELERLQSGRRKQKSKRQMDNEEEEEEEEEDDDDGSGGSGNQFEDGTTARTTDRTVVERARGDGKPTGSSFVRYHPDGTRKASTREMYLEYDDMGGGSVTHAPKASSQGMLDVNGINLLSNVVLLHGQQEEPSHAHNNNHLPESPPRHMFGELPKAKQQPPGNSRMIYTQKSATKAAPASSRKTPSARKRPAAKEQRPAAAPPPPVKLEPDADDPAIAMEALFRGRKRNASLLPEIPPHRISSVGFPLLDDGNTDDPLDEPEQRARRSTASFSASEDDLLSQQLLMEISHKSKYSERFNSDTLNDLEEILRSPVKGAGSPALAKRATTVPSTSATGKKQQQSAAKKPTSQRKRTAAPKAKAAAKAKNKPAASSTASGAGSSNSRQPPQKPVEKRAAREPPAVSSGEGSRRSSVMSTAARQTHKYGPESYAEELQMMETAEEEHVVKQEDDQGQGEHHYELGDDDVGELYLDDNDTTTSATTPAAAIGDESLHRCSICCACFDDRAQLILHVPVHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00101120;
90% Identity: -
80% Identity: -