Basic Information

Insect: Anopheles gambiae
Gene Symbol: -
Assembly: GCF_000005575.2
Location: NT:25405516-25407549[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.95 48 4.2 5.9 2 23 193 215 192 215 0.92

2 14 0.00018 0.0093 15.9 0.4 2 21 234 253 233 254 0.94

3 14 0.00042 0.021 14.7 2.1 1 21 259 279 259 281 0.94

4 14 0.16 8 6.7 0.8 1 23 287 310 287 310 0.93

5 14 0.004 0.2 11.7 1.0 1 21 322 342 322 343 0.95

6 14 0.0045 0.23 11.5 0.7 1 23 347 370 347 370 0.96

7 14 0.0067 0.34 11.0 0.2 3 23 382 403 380 403 0.91

8 14 0.0046 0.24 11.5 0.9 1 21 420 440 420 441 0.94

9 14 8.9e-06 0.00045 20.0 0.7 1 23 448 470 448 470 0.98

10 14 4.6e-05 0.0023 17.8 2.7 1 23 476 498 476 498 0.98

11 14 1.5e-06 7.6e-05 22.5 0.3 2 23 506 527 505 527 0.96

12 14 6.2e-05 0.0032 17.4 1.4 1 23 533 555 533 555 0.98

13 14 1.4e-07 7.1e-06 25.7 1.2 1 23 561 583 561 583 0.98

14 14 8.3e-06 0.00042 20.1 1.8 1 23 592 615 592 615 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.95	48	4.2	5.9	2	23	193	215	192	215	0.92
2	14	0.00018	0.0093	15.9	0.4	2	21	234	253	233	254	0.94
3	14	0.00042	0.021	14.7	2.1	1	21	259	279	259	281	0.94
4	14	0.16	8	6.7	0.8	1	23	287	310	287	310	0.93
5	14	0.004	0.2	11.7	1.0	1	21	322	342	322	343	0.95
6	14	0.0045	0.23	11.5	0.7	1	23	347	370	347	370	0.96
7	14	0.0067	0.34	11.0	0.2	3	23	382	403	380	403	0.91
8	14	0.0046	0.24	11.5	0.9	1	21	420	440	420	441	0.94
9	14	8.9e-06	0.00045	20.0	0.7	1	23	448	470	448	470	0.98
10	14	4.6e-05	0.0023	17.8	2.7	1	23	476	498	476	498	0.98
11	14	1.5e-06	7.6e-05	22.5	0.3	2	23	506	527	505	527	0.96
12	14	6.2e-05	0.0032	17.4	1.4	1	23	533	555	533	555	0.98
13	14	1.4e-07	7.1e-06	25.7	1.2	1	23	561	583	561	583	0.98
14	14	8.3e-06	0.00042	20.1	1.8	1	23	592	615	592	615	0.98

Sequence Information

Coding Sequence: ATGGACCACATCCTCATCGAGCCGGACTGCTACAAGGTGTGCCGGATCTGCATGGAAAGCTGCGAGGAcgactgtgtgtgcgtgtacgacGAGTTCGAGGACGTGCTGCTGAGCGACGTGATCCGAGAGTGTGCCCGGGTCGAGATCCGCAAGAACGATGCACTGCCTCGCAACGCTTGCCGGAACTGTGCCGAGTATCTGATCATCGCGTACCACATCATACAGAAGTGTCGCGATTCGGACGTGACCCTGCGGTCCATCTTTAAGCACGAGCTAAACTTGCACCGCGAAGAGCGCAAACCGAACACGTCGTCGGTGGTCGGGTTGCGTGCGGACGATATGGACCCGTCAGGCTACGAGTTCCTGCTAGCGAACGGGTACGACACCATGATGCTGGAGGGTGAAGGTATGCTGCTGGAGAATGCGGACTGCGACTTTACCGCACCGAGCGATGAGAAAGCTGACAGCGTTCAGGAGGAAGAAAAGGCACTTGCAGCGCGGCGCCTGGTTACGGGTGAAACGGTTCACGAGTCGAGCGAAACCACCGAAGAGGACGGTTCGTGCAACGAGCAGAAGAAGTGTTGCGGCTGCCGGAAGCTGTTCAGCAGCGAACAAAGCTTACGGGAGCACTGCCAAACGGTCCACCTGCCGGTGGAATCGTCCGCATCGGATGGACCAGCCAGCGAGAGCAAACCGATCCGCTGCCCGGTATGCTTTAAACGGTTCAGCTCGCGCCAGTTGCTGAAAGAGCACGAACGCTCCGTCAACCggaagtatgtgtgtgcgcagtGCGGCAAGCGTTTCATGACGCAGGCCAACCTGGACACCCACACCAAATGCCACAAGAACAAGGAAACGTACAAATGTTGCGGCTGCCGGATGGATTTCGAGCAGGAGCTGGATCTGCTCGTTCACTCGCAAAACGTGCACCGGCTGGAGCGGTCGGTCGATCCGGACAAACCGTTCGAGTGTGACACGTGCTATCGGCGCTACCCGACGCGCAAATCGCTCGCCACCCACAAACGCCAGATCCGCCAGTTCCAGTGCCCGCTGTGCGGTGCCATGTTTATGAAGCAGCTCTTCCTGCAGCTGCACCACGAGCGCGCTCACCAGCAGGAGGCGCAGGAGAAGCGCCGCCGGTGCTGTGGCGGTTGCCGCGAGGTGTTCGAGAATGCGGCCGCCCTGCGCGCTCACTCCGAGCGGGTGCACAAACCGGCCGACGGGTCGGCCGGCTCCGGCACGGACGACGGCAAACCGTTCGAGTGTAACGTGTGCCGGAAGCGGTTCGCGTCGATCTTTTTCCTACTTCAGCATCAGCAGAAGGTGGCGCGCGAAAAGTGCTACCCGTGCACCGTGTGTGGCCGCACGTTTGGGCGTGCGCACGATCTGTCCAACCACGAGACGACCCACTCGAACGAGATGCCGTTTGAGTGTAGCGTTTGCAGCCGGCGGTTCAAGAACAAGCTGTACCTGAAGAACCATCTTAAGCTGCACGCGAGCAGCGCCAAGGAGCAGGTGTGCGTCGAATGCGGCAAAGCGTTTCGCACGAAGGATCTGCTCAAGACGCACCTCATCAGCCACTCCCAGGTGCGCAAGTACGCTTGCACCGTGTGTCCGGCGACGTTCAAGCGGTTGCAGTGTTTGAAAATTCACACCCGCGTACATACGCGCGAGAAAGCGTTCGAGTGTGCGGTTTGTCGCAAGCGGTACGTGCAATCGTCGGATTTGAAGCGACACATGCGCACGCACAATCCGGGCGACGAGGGGAAACCGTTCCAGTGTGAGTACTGTTTGAGGCGGTACCCGCGCAAGGACTATCTGAAGGTGCACATTCGCAAGCAGCATCTGGAAAAGACG
Protein Sequence: MDHILIEPDCYKVCRICMESCEDDCVCVYDEFEDVLLSDVIRECARVEIRKNDALPRNACRNCAEYLIIAYHIIQKCRDSDVTLRSIFKHELNLHREERKPNTSSVVGLRADDMDPSGYEFLLANGYDTMMLEGEGMLLENADCDFTAPSDEKADSVQEEEKALAARRLVTGETVHESSETTEEDGSCNEQKKCCGCRKLFSSEQSLREHCQTVHLPVESSASDGPASESKPIRCPVCFKRFSSRQLLKEHERSVNRKYVCAQCGKRFMTQANLDTHTKCHKNKETYKCCGCRMDFEQELDLLVHSQNVHRLERSVDPDKPFECDTCYRRYPTRKSLATHKRQIRQFQCPLCGAMFMKQLFLQLHHERAHQQEAQEKRRRCCGGCREVFENAAALRAHSERVHKPADGSAGSGTDDGKPFECNVCRKRFASIFFLLQHQQKVAREKCYPCTVCGRTFGRAHDLSNHETTHSNEMPFECSVCSRRFKNKLYLKNHLKLHASSAKEQVCVECGKAFRTKDLLKTHLISHSQVRKYACTVCPATFKRLQCLKIHTRVHTREKAFECAVCRKRYVQSSDLKRHMRTHNPGDEGKPFQCEYCLRRYPRKDYLKVHIRKQHLEKT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00095209;
90% Identity: iTF_00107131;
80% Identity: -