Basic Information

Insect: Anopheles gambiae
Gene Symbol: ZFY
Assembly: GCF_000005575.2
Location: NT:14427459-14439915[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 1.2e-06 6e-05 22.8 2.0 1 23 10 32 10 32 0.99

2 15 3.5e-05 0.0018 18.1 0.4 1 23 38 60 38 60 0.99

3 15 0.00026 0.013 15.4 0.9 1 23 66 88 66 88 0.98

4 15 0.29 15 5.8 0.0 1 23 164 188 164 188 0.93

5 15 1.1 55 4.0 0.4 12 23 193 204 192 204 0.85

6 15 8.2e-07 4.2e-05 23.3 1.8 1 23 210 232 210 232 0.99

7 15 0.19 9.5 6.4 8.5 1 20 289 308 289 311 0.94

8 15 5e-05 0.0025 17.7 2.2 1 23 317 339 317 339 0.97

9 15 1.8e-06 9.1e-05 22.2 2.6 1 23 345 367 345 367 0.95

10 15 8.5e-07 4.3e-05 23.2 2.9 1 23 407 429 407 429 0.99

11 15 0.0011 0.057 13.4 1.0 1 23 435 457 435 457 0.98

12 15 7.4 3.8e+02 1.4 0.2 2 23 669 692 668 692 0.78

13 15 0.0073 0.37 10.8 3.2 2 20 698 716 697 719 0.94

14 15 2e-05 0.001 18.9 1.0 1 23 725 747 725 747 0.97

15 15 1.1e-06 5.4e-05 22.9 1.3 1 23 753 775 753 775 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	1.2e-06	6e-05	22.8	2.0	1	23	10	32	10	32	0.99
2	15	3.5e-05	0.0018	18.1	0.4	1	23	38	60	38	60	0.99
3	15	0.00026	0.013	15.4	0.9	1	23	66	88	66	88	0.98
4	15	0.29	15	5.8	0.0	1	23	164	188	164	188	0.93
5	15	1.1	55	4.0	0.4	12	23	193	204	192	204	0.85
6	15	8.2e-07	4.2e-05	23.3	1.8	1	23	210	232	210	232	0.99
7	15	0.19	9.5	6.4	8.5	1	20	289	308	289	311	0.94
8	15	5e-05	0.0025	17.7	2.2	1	23	317	339	317	339	0.97
9	15	1.8e-06	9.1e-05	22.2	2.6	1	23	345	367	345	367	0.95
10	15	8.5e-07	4.3e-05	23.2	2.9	1	23	407	429	407	429	0.99
11	15	0.0011	0.057	13.4	1.0	1	23	435	457	435	457	0.98
12	15	7.4	3.8e+02	1.4	0.2	2	23	669	692	668	692	0.78
13	15	0.0073	0.37	10.8	3.2	2	20	698	716	697	719	0.94
14	15	2e-05	0.001	18.9	1.0	1	23	725	747	725	747	0.97
15	15	1.1e-06	5.4e-05	22.9	1.3	1	23	753	775	753	775	0.95

Sequence Information

Coding Sequence: ATGCTTACGCACACCGGTGAAAAGCCGTTCAAATGCACGTACTGTGAGCGCAGCTTCGCGCAAAGCAACGACATGGTGAAGCACATGAAAACGCACGTGGGCGAAAACCCGTACCAGTGCGATCGGTGTGAAGCATCCTTCGCGCAAAGCAACGTGCTCGTGAAGCACATGAAAACGCACGTCGGCGACCATCCGTACCAGTGCGATCGGTGTGACGCGTCCTTCCGGCTGCTGAAGGACCTGCGCAACCACTATCAGGAGCACTACGTGGAGAGTGAGAACGGTATCGGGCCGTCCCCGAGCAAGATAAATGATGGCAGGCGTTCAACGACGCGTGAAAAAGGCAACGCCACTCTAGACAACAGCACCACCTCCCGATCGGATGACGATACCGAACCAAATTGCAAGAAAAGTATCGAAAAATTGAACGATACGACAGCAGAAGAAGCGCTCCCGCACGAGGAGAAGctcgaaacgaaaaaagatcTCTACAAATGTGTGCTGTGCGATGTTCCGGCGTTCACCGGGCCGGACGCACTGACCGACCATCTGAAGGCGGCGCATCCGGACCAGATACGGGCCTACATGGTAAAGCGGCACATGCGGACCCACACGGGCGAAAAGCCCTACAAATGTACGTACTGTGAGCGCAGCTTCGCACAGAGCAACGACATGGTGAAGCACATGAAAACGCACAAAGGACCCGGCAGGAAGCCAAAGCAACCAAAGGAGGAAAGTGACAACGATACGGAGGAACCGAAAACGAAGGTCGACCTGTACCGCTGTCTGCTGTGCGATGCACCGACCTACACCTCGCCGAAGGAGCACACCGACCATCTGCTGAAGGAACATCCGGACCAGATACATTGCTGCAAGCAGTGCCCGAAGGTGTTCATGACCAAGGCGGCCTTCGAGCATCACCAGTACTGTCACGCGACGGGGCGTTCGTTCTTCTGCATGTTTTGCGACAAAGGCTTTCAGACGGAGCAGCTGCTGAAGAACCACATGCGGACGCATACGCACGGGACCGGGTTcctgtgctcgcactgtgggCAGGAGTTTAGCAATCGGAGCAATCTGCGCCAACACTTGATACGGCACACGGGTGAGAAGCCGTGGCAGTGTAATCTGTGCCCGAGTCGTTTCAGTATGAAGAGTAAATTCACCTCGAGCCACCACGTGAAACGGCACATGCTTACGCACACAGGCGAGAAACCGTTCAAGTGTACGTACTGTGAGCGCAGCTTCACGCAAAGCAACGACATGGTGAAGCACATGAAAACGCACGTGGGCGAAAATCCATACCAGTGCGATCGGTGTGAAGCATCGTTCCGGCTGCTCACCGATCTACGCAATCACTACAAGGACCACTATCTGCCGGGCGGCAAGGATGCACTGTCCGGTGAGGAGGACAAGGACCAAACCATGACGATACAGCTAACGTTCTGTCGTATCTGTGCCGTCCTCAGCACGGAGGAGCATTGCATCTACGAAGTGGCGTACAGTGCCGGCACACTCAGCATGCACGCGATGATGGAAAAGCTAGTTCCCTCGGTGTTCAACGCGGAGCAGGTAAAGGTGGACGAGTTTATGTCCTTTCCCACGAAAGTGTGCGGCAGTTGCAAAGCCAAAGTGCTCGAGGCGTACGGGCTGTACGAGCAGTGCGTGAGGAGTGGCGATCTGCTGCGCGACTGTTTAGCGCGTAAGAAAAACGCAACGTTCATCGTGAACATAACcggtgctggcggtggtggtggtggtggtggtggtggggtggATAGTTCCGAGGGCAAAATCATTGTCCCGCTGGCGTACGAAACGGAGGAAGTGTCGGTAGGTGGCAAACCTCACACTACAACGGTGGTTGAGATAACGACGGAAGAAATCGGCCCACACTGTAAGGTGGAAAGTGAAGGCGAAAGTGAGATGGTGGAAAAGCACGACGACACTGCCGACGTGCTGTTAGAAACAACGGAAGAACCAAAACTGAATCCCGTTCAATTGCGCTGCCTACTGTGCAATCGACCAGCGTTTGCCGCACCGGCGGAACTTACGCAGCACCTGCACAGCGAGCATGCGGATCAAATATTGCGCTGCACCCTCTGCCCGAAAGTGTTCATGACCAAGGCGGCCTTCGAGCATCACCAGTACTGTCACGCGACGGGGCGATCGTTCTTTTGCGCGCTGTGCGATAAAGGCTTTCAGTCGGAGCAGCTGCTGAAGAACCACATGCGGACGCACACGCACGGGACCGGGTTCCTGTGCTCGCAGTGTGGCAAAGAGTTTAGCGATCGAAGCAACCTACGCCAGCACGAGCAGCGCCACACCGGCGAGAAACCCTGGGCATGCAGCATGTGT
Protein Sequence: MLTHTGEKPFKCTYCERSFAQSNDMVKHMKTHVGENPYQCDRCEASFAQSNVLVKHMKTHVGDHPYQCDRCDASFRLLKDLRNHYQEHYVESENGIGPSPSKINDGRRSTTREKGNATLDNSTTSRSDDDTEPNCKKSIEKLNDTTAEEALPHEEKLETKKDLYKCVLCDVPAFTGPDALTDHLKAAHPDQIRAYMVKRHMRTHTGEKPYKCTYCERSFAQSNDMVKHMKTHKGPGRKPKQPKEESDNDTEEPKTKVDLYRCLLCDAPTYTSPKEHTDHLLKEHPDQIHCCKQCPKVFMTKAAFEHHQYCHATGRSFFCMFCDKGFQTEQLLKNHMRTHTHGTGFLCSHCGQEFSNRSNLRQHLIRHTGEKPWQCNLCPSRFSMKSKFTSSHHVKRHMLTHTGEKPFKCTYCERSFTQSNDMVKHMKTHVGENPYQCDRCEASFRLLTDLRNHYKDHYLPGGKDALSGEEDKDQTMTIQLTFCRICAVLSTEEHCIYEVAYSAGTLSMHAMMEKLVPSVFNAEQVKVDEFMSFPTKVCGSCKAKVLEAYGLYEQCVRSGDLLRDCLARKKNATFIVNITGAGGGGGGGGGGVDSSEGKIIVPLAYETEEVSVGGKPHTTTVVEITTEEIGPHCKVESEGESEMVEKHDDTADVLLETTEEPKLNPVQLRCLLCNRPAFAAPAELTQHLHSEHADQILRCTLCPKVFMTKAAFEHHQYCHATGRSFFCALCDKGFQSEQLLKNHMRTHTHGTGFLCSQCGKEFSDRSNLRQHEQRHTGEKPWACSMC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -