Agam010731.1
Basic Information
- Insect
- Anopheles gambiae
- Gene Symbol
- -
- Assembly
- GCF_000005575.2
- Location
- NT:9780774-9827517[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.074 3.8 7.7 0.2 3 23 287 307 285 307 0.93 2 12 3.6e-05 0.0019 18.1 0.8 2 23 322 343 321 343 0.97 3 12 6.2e-05 0.0031 17.4 0.7 2 23 355 376 354 376 0.97 4 12 4.3e-06 0.00022 21.0 0.6 1 23 382 404 382 404 0.99 5 12 5.1e-06 0.00026 20.8 2.1 1 23 411 433 411 433 0.98 6 12 1.5e-05 0.00076 19.3 1.7 1 23 439 461 439 461 0.97 7 12 4.4e-06 0.00022 21.0 0.2 1 23 467 489 467 489 0.97 8 12 6e-06 0.0003 20.6 1.5 1 23 495 518 495 518 0.97 9 12 3.1e-05 0.0016 18.3 0.9 1 23 524 547 524 547 0.97 10 12 8.2e-05 0.0042 17.0 4.6 1 23 553 575 553 575 0.99 11 12 6.2e-05 0.0032 17.4 1.8 1 23 581 603 581 603 0.96 12 12 0.00014 0.0072 16.2 0.5 1 22 609 630 609 633 0.91
Sequence Information
- Coding Sequence
- ATGGAAGATATGTTTGGCGATATGGAAGCGCTGAACCCGGATGACATACACCTTAATTCATCCAGCGAGCAGCTTGATAGTGAGCTGCCCAAATTGGGTATCGAGTGGGAAACGATAACAGAATCAAATGAAGGAAGTATGCCATCCATTTCTCTAATACGTCCCACAGCTGCgctgggagaagaaactccccATCCGGTTGGGCATATTAAGGAAGAATTGTTTACACCTCCTTCGGAAGAAAGTGAGCAGCTGCAGCCGATCGATTCGGCACTGATGGAGGAAAACGCTCCAGAAGCGTCACTTATTGGGAAGCTAGAGCAAGCCACCTCAAAGTTGCTGCCAATTGATACTGACGACACGCAAACCGTTGGTCAGGAACTGTCCGAAGAGGAAACGCTGCACCGGTTTATGCTAGAATCGAACGAAACAATCGTTGAAGTAGCTGGTGAAGATGGCACATCGATTTACTGCGTTTATAATGACGTCATAGAAACGCTCAGTGATACGGAGGAACAGTCTGAGACGGTAACGAAGGCGCTGGAAAGTGTCAATGCCGGAAATTTGTTAGAGTATGATGATGTGATTATTGATAGTGCATCGCAGATCAGCGCACACGAGGCGTATGAGATTGGGGAATCAACGTCATCCCCCTCGCTGATGTTGGAAAACGCGAATGTGACCAGATCGCGTTCACCGTCACCATCTCAGCAGGAGGAACCTTTACAACCGTTTTACGTTAAAGTTGGAACCGACTACTACTGTACCGTTTGCTCTACGGACGATCCGGTTAAGGCGGACTGTCTGAAAAGCATGGCGCACCACTTGGCCGAAGAGCATGGTCAACAAACGCACCTGTGCGAGTTGTGTGATGTCATATTTTTCCAGAAACCATCTTACGTCGCCCATTTAGCCGAACACAGCGCCTCCGACGATCAGGACATGGAACGCGGCGTCTCATTAAGCTGCAACGTGTGCAGCGAAACGTTCACCAGCAAGCGCGCCCTTGAGCTGCACCGTAAAATGCACCCGCGAACGTCGCACGTCACGAACATGATCTGGAGCTGCGAGGTTTGCAACAAGAAGTATACCTCGAAAGCGTTCTACGAGGTACACATGAACAAGCACGCCGGGCTGCGACCGTACAAGTGTGACCTGTGTGCGAAAGACTTCTCCTCCAAGTATGCGCTAGCGGTGCACCAGAAAACGCACAACGAGCGTCCCCGCACCTTCGTGTGCAACGAGTGCGGCAATTCGTTCTACAGCCGGCACAATCTGGTACAGCACGAGCGGACGCATCGGGCGGTGCGCGAGTACGAGTGTGCCGTGTGCCGGAAGAAGTTCTTCACGCAGCACAATTTAAACGTGCACATGGTGATACACAGTGCGGATAAGGCGTTCGCTTGCCGGGAGTGTGGCAAAAAGTTTGCGCGCAAGGCGGAGCTGCTAGACCACGAGCGTATTCACACAGGTGAAAAACCGTTTGCGTGCGATATGTGCGATGCAAGCTTTGCGCAACGGTCAAATCTTCATTCGCACCGGCGGATGACGCATTTGAATGACAAACGGTTTAAGTGCGATCGATGTGATGCGGCCTTTAAACGGCGCCGATTGCTCACCTACCACATCAGGGCGATGCACACTGGTGAGCGACCGTACAAGTGTGATCTCTGCCACGCGACCTTCGTCTATCCGGAACACTTTCAAAAGCATAAGCGAATCCATACCGGCATCAAACCGTACGCCTGCGAGGTGTGCCATCGGACGTTCACCAGTCAGGACAATCGCAATGCGCACCGGTACGTGCACAGTGACAAGAAACCGTTCGAGTGTGTCACGTGCGGTGCCGGTTTTATGCGCAAATCGCATCTGTACACGCACATGCAGGAGGTGGGCCATCTGAGTGATACGATCGTGGTGAACCAGCCGCGCATTAGCGCCAACCGTACGCTGGAGTTTGAGACGGACACGTACGTGACCGATGGTACGGGTGAGGGCGAGCAGGGCCAGGAAATGGAGGGTTCGGATGAGGAGAACGTACAGTTAACGTACATTTGTGACGATGATAATGTGGACGGTGAGttggaagcggaatag
- Protein Sequence
- MEDMFGDMEALNPDDIHLNSSSEQLDSELPKLGIEWETITESNEGSMPSISLIRPTAALGEETPHPVGHIKEELFTPPSEESEQLQPIDSALMEENAPEASLIGKLEQATSKLLPIDTDDTQTVGQELSEEETLHRFMLESNETIVEVAGEDGTSIYCVYNDVIETLSDTEEQSETVTKALESVNAGNLLEYDDVIIDSASQISAHEAYEIGESTSSPSLMLENANVTRSRSPSPSQQEEPLQPFYVKVGTDYYCTVCSTDDPVKADCLKSMAHHLAEEHGQQTHLCELCDVIFFQKPSYVAHLAEHSASDDQDMERGVSLSCNVCSETFTSKRALELHRKMHPRTSHVTNMIWSCEVCNKKYTSKAFYEVHMNKHAGLRPYKCDLCAKDFSSKYALAVHQKTHNERPRTFVCNECGNSFYSRHNLVQHERTHRAVREYECAVCRKKFFTQHNLNVHMVIHSADKAFACRECGKKFARKAELLDHERIHTGEKPFACDMCDASFAQRSNLHSHRRMTHLNDKRFKCDRCDAAFKRRRLLTYHIRAMHTGERPYKCDLCHATFVYPEHFQKHKRIHTGIKPYACEVCHRTFTSQDNRNAHRYVHSDKKPFECVTCGAGFMRKSHLYTHMQEVGHLSDTIVVNQPRISANRTLEFETDTYVTDGTGEGEQGQEMEGSDEENVQLTYICDDDNVDGELEAE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00107127;
- 90% Identity
- iTF_00107127;
- 80% Identity
- -