Agam011567.1
Basic Information
- Insect
- Anopheles gambiae
- Gene Symbol
- Zbtb41
- Assembly
- GCF_000005575.2
- Location
- NT:24194093-24215261[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 25 0.01 0.53 10.4 1.6 1 23 32 55 32 55 0.94 2 25 0.00043 0.022 14.7 1.9 2 23 62 84 61 84 0.95 3 25 4.6e-06 0.00024 20.9 1.5 1 23 90 112 90 112 0.98 4 25 0.00048 0.025 14.6 3.2 1 23 118 141 118 141 0.90 5 25 5.3e-05 0.0027 17.6 0.4 2 23 148 170 147 170 0.96 6 25 0.0007 0.035 14.1 2.3 1 23 176 199 176 199 0.95 7 25 0.00011 0.0057 16.5 0.9 2 23 206 227 205 227 0.96 8 25 0.036 1.8 8.7 1.6 1 23 233 255 233 255 0.92 9 25 8.5e-06 0.00043 20.1 1.5 1 23 260 282 260 282 0.97 10 25 6e-05 0.0031 17.4 2.9 1 23 288 311 288 311 0.97 11 25 7.9 4e+02 1.3 1.2 2 19 318 335 317 339 0.58 12 25 0.0026 0.13 12.3 0.9 1 23 345 368 345 368 0.91 13 25 0.00029 0.015 15.3 0.4 2 23 375 396 374 396 0.96 14 25 0.00036 0.019 14.9 1.2 2 23 403 424 402 424 0.96 15 25 0.0088 0.45 10.6 4.3 1 23 430 452 430 452 0.95 16 25 0.032 1.6 8.8 0.3 1 23 457 477 457 477 0.96 17 25 0.0087 0.44 10.6 1.0 1 23 483 505 483 505 0.92 18 25 0.00024 0.012 15.5 2.3 1 19 510 528 510 529 0.96 19 25 5.3 2.7e+02 1.9 3.3 3 23 568 585 567 585 0.87 20 25 6.5e-07 3.3e-05 23.6 0.2 1 23 591 614 591 614 0.97 21 25 6.5e-05 0.0033 17.3 1.7 2 21 621 640 620 645 0.93 22 25 0.0087 0.44 10.6 1.0 1 23 651 673 651 673 0.92 23 25 1.3e-06 6.5e-05 22.7 2.0 1 23 678 700 678 700 0.98 24 25 0.00013 0.0064 16.4 3.1 1 23 706 729 706 729 0.96 25 25 3.4 1.7e+02 2.5 0.3 1 11 735 745 735 747 0.86
Sequence Information
- Coding Sequence
- GAGCACCGCAAGAAACGGCAGCTGTGCGTCGAATGCGGCAAGATGGTGCTGCAGCTCTCCGCCCACCGGTTAACCCACACGCAGGAGAAACAGTTTTCCTGCCCCCACTGTCCGATGAAGATGAAAAGCAAGGGCAACATATGCCGGCACATCGAGGCGGTGCACTTGAAGAAGCCGGCGAAAACGTGCGAAACATGTGGGAGAGAGTTTGTGCACGCCAACATGTACAAGTACCATATGCGTGCCAAACACGGCTTCGGTGAACCATTTGAATGTACCATATGCAACATTAAATTTCGCCATAAAGGCGGATTGCGGGACCACATGCTGTCCCATACGAAGGAACCGAAGTTTTCCTGCCAGCACTGCCCGATGACGTGCAGCCGCAAATCGTACCTCAAGCTGCACGTGGACGCCGTGCACAAGAAGCGCATCATAAAGAGCTGCGAAATGTGCGACAAAGGCTTCAGTTATATCGAATCGTATGAGGCTCATATGcgaTCGAAGCACAACTACGGAGAATCATTTGAATGTACCATATGCAACATTAAATTTCGCCATAAAGGCGGATTGCGGGGTCACAACAATCGCAAGCACAACGATCAAACCAACTGCTCCTGTGACATTTGTGGCATGAAGTTTCAGGACAAGAGAGGGTTACGCGCTCATGGTAGGGTACATTCGGACGAGAAACCCTTTGCCTGCCAGTTCTGCCCGAAGCGCTTCAAGAGTCCAAACGCGCACAGAACGCACGAGCTGATCCACAAGGGCGTTGTATTTCCTTGCACGATGTGCGATAAAACGTACACGTACAAATCGTTGCTCAATATGCACCGCGCCAAACACAACCTGGGAGAGTATTTTGAGTGTAAAATATGTTCGAAGAAATTTCGCCACCGTGGCGGACTGAATGGCCACCTAAACCGCAAGCACAACGAGGAGAGCAACTGTACCTGTCCGCTGTGCCCGATGTGCGGTAAGCTGGTGTACGACCTTCCGGTCCATATAGTATCGCACACGAAGGAGCGCAAGCACGTCTGTCCCCATTGTTCCATGGCTTATGGGCGCAAAACGTACCTGAAGATGCACGTGGAAGCGGTGCACCTGAAGAAGGTGGTCAAAACGTGCGAACTGTGCAATCGCGGTTTTACGCAACGAACCGGCTACGAAGCACACATGGTAAGCCACAACGAAAAATCCAACTGCTCGTGCCCGACCTGTGGCATGGAGTTTCAAAGCAAAGTTGGGCTGAAAAATCACAGCAGGGTGCACTCCGTGGTGCAGATGTTTGCGTGCAAGCACTGCCCGAAACGGTTCAAAAGTCCCAACGCGCACAAGCAACACGAGCTTACCCATTTGGGCGTTACCTTTCCCTGTCCGGTTTGTGCGAAAACGTACCGCTACGGATTGAAGAAACATGGCCGAGTGCACTCGAACGAGCAACCGTTTGCGTGTCGCTACTGTCCGAAGCGTTTCAAGAGCCCGAACGCGCACCGGGCACACGAGCTGATCCACCAGGGTGTCGTGTTCACGTGTGAATACTGTAAGAAAACCTATCGGTACAAATCGCTGCTCAATATGCATAAACCACGGAAACCGTACGTGCGACGGGCGACGATTGGTAAAGAGCAGGATAGTTCGGTGAAAAAACCACGGGTGTATAAGAAGCGACCAAATCGAAACAAGCTGCCCAAGAAGCTGTGCACGGTGTGTGGTAAGTTTGTGGCCCACTTGAACCATCACCTTCTATCGCACACAAAGGAACGAAGGTTCCCTTGCACATACTGTCCGAGGGCTTTCAGTCGCAGCTCGTTATTGAAGGTGCACGTAGAAACGGTACATCTGAAGAAGACGGCCAAGAGCTGTGAGCTGTGCGATAGGAGCTTTTCGTACAAATCCAGCTACACGATCCACATGAAACATGGCCGAGTACACTCGAACGAACAACCGTTTGCGTGTCGCTACTGTCCGAAGCGTTTCAAAAGCCCGAACGCGCATCGGGCACACGAGCTGATCCACCAGGGTGTTGTGTTCACGTGTGAGTACTGTGAGAAAACCTATCGGTACAAATCGCTGCTCAATATGCATCTCCGAGTGCACGGCATTGGGAAAACGTTCGACTGCCACATGTGTGCCAAAAAGTTCAACCACAACAGTGGGCTTAAATCGCACATTGCCCGTGTGCACAGCAATGAGCGAAAGTTTGAGTGCGAAACGTGTGGCATGCTGTTTAAAGTGAAGTAA
- Protein Sequence
- EHRKKRQLCVECGKMVLQLSAHRLTHTQEKQFSCPHCPMKMKSKGNICRHIEAVHLKKPAKTCETCGREFVHANMYKYHMRAKHGFGEPFECTICNIKFRHKGGLRDHMLSHTKEPKFSCQHCPMTCSRKSYLKLHVDAVHKKRIIKSCEMCDKGFSYIESYEAHMRSKHNYGESFECTICNIKFRHKGGLRGHNNRKHNDQTNCSCDICGMKFQDKRGLRAHGRVHSDEKPFACQFCPKRFKSPNAHRTHELIHKGVVFPCTMCDKTYTYKSLLNMHRAKHNLGEYFECKICSKKFRHRGGLNGHLNRKHNEESNCTCPLCPMCGKLVYDLPVHIVSHTKERKHVCPHCSMAYGRKTYLKMHVEAVHLKKVVKTCELCNRGFTQRTGYEAHMVSHNEKSNCSCPTCGMEFQSKVGLKNHSRVHSVVQMFACKHCPKRFKSPNAHKQHELTHLGVTFPCPVCAKTYRYGLKKHGRVHSNEQPFACRYCPKRFKSPNAHRAHELIHQGVVFTCEYCKKTYRYKSLLNMHKPRKPYVRRATIGKEQDSSVKKPRVYKKRPNRNKLPKKLCTVCGKFVAHLNHHLLSHTKERRFPCTYCPRAFSRSSLLKVHVETVHLKKTAKSCELCDRSFSYKSSYTIHMKHGRVHSNEQPFACRYCPKRFKSPNAHRAHELIHQGVVFTCEYCEKTYRYKSLLNMHLRVHGIGKTFDCHMCAKKFNHNSGLKSHIARVHSNERKFECETCGMLFKVK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -