Agam000965.1
Basic Information
- Insect
- Anopheles gambiae
- Gene Symbol
- -
- Assembly
- GCF_000005575.2
- Location
- NT:17951113-17958430[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 22 0.0098 0.5 10.4 5.6 1 20 6 25 6 29 0.95 2 22 0.00039 0.02 14.9 0.8 2 23 37 58 36 58 0.97 3 22 3.9e-06 0.0002 21.2 0.3 1 23 66 88 66 88 0.98 4 22 0.00023 0.012 15.6 5.7 1 23 94 116 94 116 0.98 5 22 8.1e-07 4.1e-05 23.3 3.7 1 23 122 145 122 145 0.97 6 22 0.016 0.82 9.8 0.4 1 23 151 173 151 173 0.98 7 22 1.6e-05 0.00079 19.2 0.7 1 23 181 203 181 203 0.98 8 22 5.6e-06 0.00028 20.7 0.8 1 23 209 231 209 231 0.97 9 22 2.9e-06 0.00015 21.5 2.2 1 23 237 259 237 259 0.98 10 22 0.00023 0.012 15.6 0.9 5 23 272 291 271 291 0.96 11 22 0.0057 0.29 11.2 0.8 1 23 297 319 297 319 0.97 12 22 9.6e-07 4.9e-05 23.1 1.0 1 23 325 347 325 347 0.98 13 22 1.1 58 3.9 0.1 9 23 363 377 354 378 0.89 14 22 0.00047 0.024 14.6 1.8 3 23 383 403 381 403 0.97 15 22 6.6e-05 0.0034 17.3 2.5 2 23 409 430 408 430 0.97 16 22 4.1e-05 0.0021 17.9 0.4 1 23 438 460 438 460 0.99 17 22 0.001 0.052 13.5 4.6 3 23 468 488 466 488 0.97 18 22 0.32 16 5.7 1.0 2 15 495 508 494 517 0.76 19 22 0.2 10 6.3 0.2 2 23 546 570 545 570 0.96 20 22 8.6e-05 0.0044 16.9 1.3 1 23 574 596 574 596 0.97 21 22 2.3e-06 0.00012 21.9 0.9 1 23 602 624 602 624 0.99 22 22 1.6e-05 0.00084 19.2 0.8 1 19 630 648 630 648 0.98
Sequence Information
- Coding Sequence
- ATGCACGGCTTTCCGCACAAGTGTGAGCACTGCTACCGGCGCTTCACGACCGTGTATCTGCTGAACCACCACCTGTGGAACTACCACCAGCACTCGAAGGAGGGTCTGACGTGCGAGTGGTGCGGCAAGCGGTACTACTCCCGGCGCCCGTTCCAGGAGCACGTGCGGCGCCACAAGCACTCCGTCACGGAGCGGTTCAAGTGCACGACGTGCGGGCGTGCGTTCGGCTCGAACGCGCTGCTGCGCCGCCACGAGATGGTGCACACGGGCGAGCGCAGCCACAAGTGCACCTACTGTCCGCGCCTGTTCAGCCGCCGGTGCAATCTGCTCGACCATCTGCGGCTGCACACGGGCGAACGGTGCCACAAGTGCAGCGAGTGTCCGCAATCGTTCAACACGAAATCGTCGCTCGAGAAGCACCAGCGCAACTACCACAGCGATCTGGCGGGTTTCACGTGTGACGTGTGCGGCGTAACGATGCAGTACCGTCCCTCCTTCATGTACCATATGCGCATCCACTACCACGAACAGATGGGCACGTTCCGGTGCCAGTACTGTGATCGTGTGTTTGGAACACGGGCCCGCCTAGAGCGTCACGAACGGGCACACACGGGCGAGCGGCCGTTCGCTTGCCATCTGTGCCCGAAAACGTTTGTGCACGCGGGCCAGCTGGCAACGCACATCGCGCGGCACAATAACGAGCGCGGCCACCGGTGCTCGCAGTGCGGCAAAGCGTTCTATAGCAAAGCGATGCTGCGGCAGCACCTGGAAACGCACGAAACGCACGAAACGCGCAAAGCGAGCAACGCGGCGAAATGTGGCCGCCGGTTTGCGCGAGCGTGCGAGCTGAGACGGCACCGGCGCATCTATCACTCCTCGGAACATCCGTTCCGGTGTGAGCCGTGCGGCAAAACGTTCCTTAGCTCGCAGAGCTACCGCGAGCACATGGACTCGCACGCCAATGTGCGCCGGTTCgagtgcgaagtgtgcgacaAAAAGTTTGTGCGCCGGCGCAACCTGGTCAACCATCGGATGTCGCACACGAACCAGCGGCCAATTTGCCAGGTGGAGGGTGGACCCGCCCGCACGCTCAAAACCATCTCCTCCCTGCAGAACCACTTCCGCTCGCACCACTACCCGTTCGGGTGCGGCACTTGCGGCAAGCGGTTCCTGCGCAAAGCGCACCTGATGACGCACATGGACAGCCACAACGAGGAGCACCTGGAGTGTGGCGAGTGCGGGCGACAGTTTACGCACCGCAAAACGTGGCAGAACCACCTGAAGCGCCACGTGGCCGTGCGGACTGGCGCGTTCAAGTGCGGCACCTGCGGCCGGGCGTTCGGCAACCGGGCCCGGTTGGATCGGCACGTGCGCTCGCACACCGGCGAGCGGCCGTTCGGGTGCAAGTACTGCGACAAGCGGTTCTACgaccgccaccagcagcagcgccacaCCGAGCGGCACTTCCGCGACCAGGAGTGCAGCTGCGAGATTTGTGGCGAAACGTTCCCGGGCGCCAAGAAGCGCGACCAGCACAAGGTCGAGCAGCATCTGAGCGGCCCGGAGCTGGAGGCGTTTTTGGCGCGCAAATCCAGACAGCGGTCGTACAAGAAGCCGGCCGTACTGAAGGATAAGAAGTGCCCGTTCGCAGGGTGCGATTACGTCGCCAACACGTACGGCGCGATGTACGTGCACAAGCGCACCAAGCATCAGCCGGTGCACAAGTGCGAGCTGTGCAACAAATCGTACGCTTTCCTCAACCAGCTGCGGGTGCACATGGCGCTGCACACGGGCGAGAAACCGTACCAGTGTGAGATTTGCGGGCGCAGCTTCCGCCGCGGGTTCAGCTACAAGGAGCACATGGAGATGCACAACCCGGAGGCGAGCTACAACTGTCCGACGTGCAACAAAAGCTTCAAGCGGCCCCGGTACCTGCAGGCGCAC
- Protein Sequence
- MHGFPHKCEHCYRRFTTVYLLNHHLWNYHQHSKEGLTCEWCGKRYYSRRPFQEHVRRHKHSVTERFKCTTCGRAFGSNALLRRHEMVHTGERSHKCTYCPRLFSRRCNLLDHLRLHTGERCHKCSECPQSFNTKSSLEKHQRNYHSDLAGFTCDVCGVTMQYRPSFMYHMRIHYHEQMGTFRCQYCDRVFGTRARLERHERAHTGERPFACHLCPKTFVHAGQLATHIARHNNERGHRCSQCGKAFYSKAMLRQHLETHETHETRKASNAAKCGRRFARACELRRHRRIYHSSEHPFRCEPCGKTFLSSQSYREHMDSHANVRRFECEVCDKKFVRRRNLVNHRMSHTNQRPICQVEGGPARTLKTISSLQNHFRSHHYPFGCGTCGKRFLRKAHLMTHMDSHNEEHLECGECGRQFTHRKTWQNHLKRHVAVRTGAFKCGTCGRAFGNRARLDRHVRSHTGERPFGCKYCDKRFYDRHQQQRHTERHFRDQECSCEICGETFPGAKKRDQHKVEQHLSGPELEAFLARKSRQRSYKKPAVLKDKKCPFAGCDYVANTYGAMYVHKRTKHQPVHKCELCNKSYAFLNQLRVHMALHTGEKPYQCEICGRSFRRGFSYKEHMEMHNPEASYNCPTCNKSFKRPRYLQAH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -