Basic Information

Insect: Anopheles funestus
Gene Symbol: -
Assembly: None
Location: Contig2:11025227-11029520[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.39 24 5.4 1.4 6 23 245 262 245 262 0.98

2 13 0.26 16 6.0 0.4 6 23 273 291 268 291 0.86

3 13 2.8e-05 0.0017 18.4 0.4 1 23 299 321 299 321 0.93

4 13 0.00034 0.021 15.0 1.7 2 23 330 351 329 352 0.93

5 13 0.75 45 4.5 0.5 2 23 405 427 404 427 0.91

6 13 0.00044 0.027 14.7 0.8 1 19 460 478 460 483 0.94

7 13 0.0022 0.13 12.5 2.9 1 23 491 513 491 513 0.94

8 13 2.4e-05 0.0014 18.7 1.5 2 23 522 544 522 544 0.97

9 13 0.0038 0.23 11.7 0.2 2 23 551 572 550 572 0.96

10 13 9.7 5.9e+02 1.0 8.5 1 23 582 605 582 605 0.96

11 13 0.0023 0.14 12.4 2.3 3 23 613 633 612 634 0.95

12 13 0.00042 0.025 14.8 1.4 1 23 640 662 640 662 0.97

13 13 0.022 1.3 9.3 1.4 1 23 668 691 668 691 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.39	24	5.4	1.4	6	23	245	262	245	262	0.98
2	13	0.26	16	6.0	0.4	6	23	273	291	268	291	0.86
3	13	2.8e-05	0.0017	18.4	0.4	1	23	299	321	299	321	0.93
4	13	0.00034	0.021	15.0	1.7	2	23	330	351	329	352	0.93
5	13	0.75	45	4.5	0.5	2	23	405	427	404	427	0.91
6	13	0.00044	0.027	14.7	0.8	1	19	460	478	460	483	0.94
7	13	0.0022	0.13	12.5	2.9	1	23	491	513	491	513	0.94
8	13	2.4e-05	0.0014	18.7	1.5	2	23	522	544	522	544	0.97
9	13	0.0038	0.23	11.7	0.2	2	23	551	572	550	572	0.96
10	13	9.7	5.9e+02	1.0	8.5	1	23	582	605	582	605	0.96
11	13	0.0023	0.14	12.4	2.3	3	23	613	633	612	634	0.95
12	13	0.00042	0.025	14.8	1.4	1	23	640	662	640	662	0.97
13	13	0.022	1.3	9.3	1.4	1	23	668	691	668	691	0.91

Sequence Information

Coding Sequence: ATGGAGGTAAAATCAGATCAGCCGGTTTGTTATGAGCTTTGTGTACTGTGTCAGTTAAACAGCACCGATCGTCATTGCTTAACTGAGCGGATACAAACCAGCAATGGTTCGATAGCAGACGTTATTTGCAAGCATTTCTGGTTGTCGGCATCCTCTTGCAAAGGGCGATACATCTGCACTACATGCTGGGACTTAACATTTTCCTTTCATCAATTCTACATCGAAATAGAGCGGGTTCACTCTGTACAATCTACAGCAACAATTAAGCAAGAGCCAAACATCACAGAACATAAGGAATTATGCCCAACCAAGCAGCCGGACTGGTTGGACGATGAAAACACATTGCTAACAATTGCAAATGAAGTATATGTAAAGGAAAACTACACGGACAGTGATGCTGAACCCATTGCCATCGAGGGCATTGATGGTACTGATCGGGACGATGTGTCGGAAAATGATTCAAATGTTCCTTTATCATCGCTCAAGCAAGAAATCATATCAACCCGCATCACCTGCCAAAACAACACCGTTGAAAGGCCTTCACCATTCCCCGGTGTAGGACTGTCGTTATCCCGTATTAACGGCCGTACGCTTGAGAATATCTGTCACGATTGTTTCCGTCAAGCCAGTCATACGCAAGCATCGGAAAAAGTGACGCAAGCACGCTTTTCCTTCGCCGCGTTGCTGAAACACTATCGGAAAGAGCACAACAAGACCGGTTATGCAGTTTGCTGCAATCGAAAGTATACGCGCAGAACGTCGATAAAGATGCATCTACTGTCACACGGCAGGAAGGTCGCATACTGCTGCATTCCGTGCGGGATAAAGTTTCGCCGACAGGAATCTTTGGACGAGCACAATCTGCTCATTCATACGTCGGAGGAGGAAAAACAGTTCAAGTGTGGTCAGTGTGATAAATCGTTCCCCACGGAAGACCTGTTGAAATCGCACGGAACGTGGCATGAAACTATTGCTAAAAAGAATATAAGTTGCAACATTTGTAACCTGTTCTTCGCCAGTCAACCGTCGCTGAAAAAGCATCGTACACTGCATCACCCATCACCGGAGAGCAATGAGGCACATCCGGCTTCGGGTAATAGCAGTAGTACCGAACCGACCGAAGAACGGCTGGTTGCTACTAAGTATCGTACTCGCATTTCAGCAGCAAAAATCAGCGAACAGGACGAGCTTATCAAGCGCCACTGTTTATTAAATTGTACCAACTGTGATTACTTTGCGGAGAGCTTCACAAAGCTCAAGCAACATGCGATGCAGGTGCATGGTATGCAAAGTTGTCATGTCGCATGTTGCGATCGTACGTACAACAAGCGTCAATCGCTGTATGACCACTGCTTGGTGCATGAAAATCCCGACTGCTTCCGCTGTAACGTGTGCGGTAATAGTTATTCCAGCAGCCGCAGTCTACAAAGCCACAAATGGCGTATACATACGCCGGCTACGGAACGTCCCTTTTGCTGCGACGTGTGTGGCGAAACGTTCGTGAAGGATTACCTGCTAAAGCAACATCTCGTACATCATCTGGCGAAGCATAAAAAGCTCAACTACTGCAACGAGTGTAATCGTTCGTTTACGACGGCGACGGTGCTCAAATCCCACCAGCAAACGTTTCACGGTGGAGGGTTCAACTGGATCTGTGATATTTGTGCAAAAGGGTTTAATGGTCGCACACTGTTTGAAAACCATCGGCTTACACATTCGATCGAAGGAAAGACACAGTTGAAGCATCAATGCGAGTTGTGTAAGAAATGGTTGCGCAATAAAAAATCATACCAGCAGCATCACATTCGCTGCCACAGTAGCGGCGGACCGGTGCTGTGTAAATTCTGCGGCAAGGAATCAATCAATGCGAGCGCATTAAAGTCGCACATACATCTGCACCACACAGCACGGCCGGAATATCCCTGTACTTTCTGCAGCAAAAGCTTCAAGACGTCACTGCGCTTACGGGAGCATGAAGCCACACATACCGGTACGATACTGTACCGGTGCCCGTGGTGTCCCCGTACCTTTGCCTGTGGTTCGAACATGTACAAACATAAGAAGGCTGGCCATCCGCAGGAATGGGCCGCCTCGGTAAAGAAACGGTTTGGTGAGCGATGA
Protein Sequence: MEVKSDQPVCYELCVLCQLNSTDRHCLTERIQTSNGSIADVICKHFWLSASSCKGRYICTTCWDLTFSFHQFYIEIERVHSVQSTATIKQEPNITEHKELCPTKQPDWLDDENTLLTIANEVYVKENYTDSDAEPIAIEGIDGTDRDDVSENDSNVPLSSLKQEIISTRITCQNNTVERPSPFPGVGLSLSRINGRTLENICHDCFRQASHTQASEKVTQARFSFAALLKHYRKEHNKTGYAVCCNRKYTRRTSIKMHLLSHGRKVAYCCIPCGIKFRRQESLDEHNLLIHTSEEEKQFKCGQCDKSFPTEDLLKSHGTWHETIAKKNISCNICNLFFASQPSLKKHRTLHHPSPESNEAHPASGNSSSTEPTEERLVATKYRTRISAAKISEQDELIKRHCLLNCTNCDYFAESFTKLKQHAMQVHGMQSCHVACCDRTYNKRQSLYDHCLVHENPDCFRCNVCGNSYSSSRSLQSHKWRIHTPATERPFCCDVCGETFVKDYLLKQHLVHHLAKHKKLNYCNECNRSFTTATVLKSHQQTFHGGGFNWICDICAKGFNGRTLFENHRLTHSIEGKTQLKHQCELCKKWLRNKKSYQQHHIRCHSSGGPVLCKFCGKESINASALKSHIHLHHTARPEYPCTFCSKSFKTSLRLREHEATHTGTILYRCPWCPRTFACGSNMYKHKKAGHPQEWAASVKKRFGER

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -