Basic Information

Insect: Anopheles funestus
Gene Symbol: ZEB2_1
Assembly: None
Location: Contig1:97803067-97805068[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.021 1.3 9.4 0.7 3 23 161 182 160 182 0.94

2 11 0.03 1.8 8.9 0.8 1 21 193 213 193 214 0.95

3 11 0.069 4.2 7.8 4.9 1 21 221 241 221 246 0.91

4 11 0.57 35 4.9 3.1 3 23 315 337 314 337 0.86

5 11 0.00028 0.017 15.3 0.6 1 21 353 373 353 374 0.95

6 11 0.00069 0.042 14.1 0.1 2 23 382 404 382 404 0.95

7 11 4.7e-05 0.0029 17.7 2.1 1 23 411 433 411 433 0.98

8 11 0.027 1.6 9.1 0.9 3 23 441 462 440 462 0.95

9 11 0.024 1.5 9.2 6.0 1 23 468 490 468 490 0.99

10 11 0.0012 0.074 13.3 1.7 1 23 496 520 496 520 0.94

11 11 1.4 86 3.6 6.5 1 21 526 546 526 551 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.021	1.3	9.4	0.7	3	23	161	182	160	182	0.94
2	11	0.03	1.8	8.9	0.8	1	21	193	213	193	214	0.95
3	11	0.069	4.2	7.8	4.9	1	21	221	241	221	246	0.91
4	11	0.57	35	4.9	3.1	3	23	315	337	314	337	0.86
5	11	0.00028	0.017	15.3	0.6	1	21	353	373	353	374	0.95
6	11	0.00069	0.042	14.1	0.1	2	23	382	404	382	404	0.95
7	11	4.7e-05	0.0029	17.7	2.1	1	23	411	433	411	433	0.98
8	11	0.027	1.6	9.1	0.9	3	23	441	462	440	462	0.95
9	11	0.024	1.5	9.2	6.0	1	23	468	490	468	490	0.99
10	11	0.0012	0.074	13.3	1.7	1	23	496	520	496	520	0.94
11	11	1.4	86	3.6	6.5	1	21	526	546	526	551	0.94

Sequence Information

Coding Sequence: ATGTCTCTCCTCAACAGCAACAGCAGAAAGTTAAAGTGTACAATTTGTGCCAAAATCCTACCACGGGAAGGACTAATAAATACAACCAATGCATTCACAAGCCATTCTACCATTGGCGAAACACTAGCACAGTTTGCAGATATAGAGTTCGCTTCAAATCCGACCCTGACAGAAGGCTCCATTTGTATCGAAGACTGCTGTGATCGGTTGCGTGCTGCGATTGAATTTCAGGATTTAGTAAGAACCGTGTTTGGTCATCACCTAACTGAAGATAATGACGAACAGAATAAAACCGATTGGAAAACAAATTCCATTGAAGCAACCGTCGTCGATGTTAAGCATCGATTGGAGCAAGAGGAAAGCCCAGTAACGGAAAACTTTAAATTGTTGGGAAGGCCGTTCGTTATGCCGAAGCTCGATTATGTTCATACACACATGAGATTTAACAATCTAGAATACGTAGAGCTAAGCGGTCCAATGTGTTGCGGATGTGATTTTGTAGCGAAAACTAAGGAAAATCTTATGGGCCATATCAACGCAAAACACATGTACAGAACAAACGGTCCGAACGATTCATTCGTTTGCGATGTGTGCCGTGAAGCGTGTGAAGATGATCATCAACTAAAGAACCATCGACAGTGGTTCCTAAATACGGAAATTTTTCTTTGCAAATATTGCTCCTACGGTTTCACGTGCAAGGAAAATCTTATGCAGCACATGAGCATGTGCATCACGCATGATAAGTTGGCTACCGAAGAAGAAAGGCTTTTGGAAACGAAGAGAGTCGAACATAAAGAGCTGGAAAAACCACTGAATGATAATCTTGTAGTAAAAGTAGAGGACTATGACGATCATAGCGATTTTCACAATGACAAGGCAGCTGATATCGTACCGCAGCAGAAACCGTTCCGCGAGCTTACCCAAACCGCCAATCACGGGTGCTGTTTCTTGCGCTGTAATGCCACATTCGACCGGGAAACCGATCTGTACCGTCACGTACATGAGTTGCACGCCGCTCGTCAACGGATTCATCGAAGCGAACGTACATCCGATCGGTACGTGTGTAAAACTTGCCAGTTGAGCTTTAAAAGTGTTAAAACTTTAGAACGACATCGGAACGGTTGGAAGCTAAAGCAGAACAACGTTTGCGCGCATTGCGCTAAAGGATTTATTACTCCTGGTGAATTAAAAGATCATGTGCAGGTGGTGCATAACGACGCGACGCCCCAGTTCCGCTGTGAAAGCTGTGAGAAGCAGTTCAGGAAGAAATCCCTTCTCAAACTGCATCTGGTTACACATCAACAAGATCGCCGGCACGGTTGTGATCAGTGTGACGCACGATTCCACTTTGGCTATCAGCTGAAAAAGCATCTGCAGGCGGTCCACACAACGGAGTTTCCGTATGAGTGTAAGCACTGTGACCGGAAGATGCCAAACAAACACCGGTACGATCAGCACATGCGGATGCATACGGGTGAAAAGCCGTATGCATGTCGGAACGACTGTGGTCGCAAATTTTCACATGCCACCGACCGTCGAAGGCACGAAATGGTGACGCACACAGGTGAGAAACCGCATCGTTGCTGCAGTTGCAGTATGGCTTACGTTAGACGAAAGGAATTGCATCAACACTATCGACATTTCCCAGCACATGATACTGACAGGAAATTCATCTCAGCCGGGGTTTTGAATGCTTGA
Protein Sequence: MSLLNSNSRKLKCTICAKILPREGLINTTNAFTSHSTIGETLAQFADIEFASNPTLTEGSICIEDCCDRLRAAIEFQDLVRTVFGHHLTEDNDEQNKTDWKTNSIEATVVDVKHRLEQEESPVTENFKLLGRPFVMPKLDYVHTHMRFNNLEYVELSGPMCCGCDFVAKTKENLMGHINAKHMYRTNGPNDSFVCDVCREACEDDHQLKNHRQWFLNTEIFLCKYCSYGFTCKENLMQHMSMCITHDKLATEEERLLETKRVEHKELEKPLNDNLVVKVEDYDDHSDFHNDKAADIVPQQKPFRELTQTANHGCCFLRCNATFDRETDLYRHVHELHAARQRIHRSERTSDRYVCKTCQLSFKSVKTLERHRNGWKLKQNNVCAHCAKGFITPGELKDHVQVVHNDATPQFRCESCEKQFRKKSLLKLHLVTHQQDRRHGCDQCDARFHFGYQLKKHLQAVHTTEFPYECKHCDRKMPNKHRYDQHMRMHTGEKPYACRNDCGRKFSHATDRRRHEMVTHTGEKPHRCCSCSMAYVRRKELHQHYRHFPAHDTDRKFISAGVLNA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -