Basic Information

Insect: Anopheles funestus
Gene Symbol: RERE
Assembly: None
Location: Contig1:6173976-6327556[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 7e-05 0.0042 17.2 0.2 2 23 271 292 270 292 0.97

2 5 1.4e-06 8.3e-05 22.6 1.3 1 23 298 320 298 320 0.99

3 5 0.00011 0.0065 16.6 2.6 1 23 326 350 326 351 0.95

4 5 0.00057 0.035 14.3 0.8 2 23 686 707 685 707 0.97

5 5 0.0011 0.066 13.4 0.3 1 23 1768 1792 1768 1792 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	7e-05	0.0042	17.2	0.2	2	23	271	292	270	292	0.97
2	5	1.4e-06	8.3e-05	22.6	1.3	1	23	298	320	298	320	0.99
3	5	0.00011	0.0065	16.6	2.6	1	23	326	350	326	351	0.95
4	5	0.00057	0.035	14.3	0.8	2	23	686	707	685	707	0.97
5	5	0.0011	0.066	13.4	0.3	1	23	1768	1792	1768	1792	0.95

Sequence Information

Coding Sequence: ATGGCTGCTGTTAACTCGGTCCAGAATAGCATTCGATTGCCGTTGGCTGGATTGGCGCCACCGCGCGTCCTTATGTGTAGTGCCTCGATGGGTGCGGAAGGTTCCGTCACACTTCAGCTCCGGGAAGCGGTACAGGCGCCCGATGCTGCCGGTTCGCTGGACGGAGCGCTCACGATCGGCTACCCGGATCCGGAAATGTTGGCCGACATGCTGGGCACATTCCAGGGAGCTTCCACCGGTGCCACCGATTCGGACGCTGGCAGTTTCGATCTGCTGCAGGATAGCAACGGTAGTTCCGCGGGAGCAACGCTACGAGCAACAGCAGCCGATCAGATCGAACATCTTACCGGAGCTATACTTACCAAAACGAGCAGCAGTAGTGGTAGCAGCAACACAACAGGCACGTCCACGGTGACGATAAAAACAGAGCCGGGCACGAAACCAGCGGCGGAAAAAACGAACTCAACCTCCAACCTACTACCGAACCATACGTCCAGCACGACCATCAGCAGCAACAACCTGTCTCCATCGTCGACGGCCATCTTGCACCACGGTACCACGATGGTGACCGTGAAAAGTTCGCCCAACGTTGGAGGAAGCAATGGCAACATTGCCACCGCTGCCAGCCCTACCAGTCTCGTGCTGACGACGGTTGGTCGGGCAGAGACGGCATCCGGCAACAGCAGCAGTGCGTCGTCATCCCCGTCGGCCGCTTCCTCACCGGGCACGGTTTCGTTGAACGGGTTGTCCGGTGGACTGGCGAAGAAACCACGACCCAAGACGGTATCACCGACCCGCCACGGTCCGCAACAGTGTCAGGTTTGCAGCAAAGTGTTTGGAAATGCATCCGCACTCGCCAAACACAAGCTAACGCACAGTGACGAGCGCAAGTATGTGTGCGGCATGTGTTCGAAGGCGTTCAAACGGCAGGACCACCTCAATGGCCATATGCTGACGCATCGTAACAAAAAGCCGTACGAATGTAAGGCGGAAGGCTGTGGCAAATCGTACTGTGATGCGCGATCGCTAAGACGTCATACCGAGAACCATCACAGCGCACTTGGGCTGGCGAACTCATCCGGTACGGCAAGTCCCGGCCCTGGTGGAAGTAATGCAGGACCGCCCGGTGGGCTTAGTTTATCACCAGCGACAGCGAGCGGCGATGCAAGCTCTCCCCATGGAGCAACATTAGTCCAATTCACCACCACAACCACCGGCAACGGAACGACCGGCAGTAGCTCCAGCAACAGCAATTGTAGCCTTTCGAGCAGCAGTTCGAGCAGCAGTTCCAGCAGCAGCAGTAGCAGCAGTAGCAGCAGCAGTAGTAGCGGAAACGTTAGCGACTCCAGCTCCAGCTGCAAATCGCCTTCACCGAGCTCGCCCGCGCCAGGCTCGGGAAATGAGGGCCTTACGCGCCAACAGCTCGATCTTATTTCCCAGATCATGCAGCAGACGAAGCAGGCGAATGCAGCGGCCGCTGCTGCTGCCGCCGCTTCCAGTGTCAGTGCGAGCGGTAACGGCACCGGACAGTTGCTCACCACCAGCCAGAAGGTTCCGGTACGTCCACGAACCTGGAATATGCAGCTGCAGCTCAGCCAGAACAAGCTGTCCGCAACTACCGCAACGACGGCGACGACACTAACGTCAGCGGTGGCGTCGACAACGGCGACGGTGGTTAGTGCAGTGCCAGTGCCTTCAATGGCAGTCGGACAGACGACCACGCTGTCCACCTCCAACGCCGTCAACCCCACCATCATCAGCTCACACCCGAACGGTACCATCACCACCAACATCATCAGCAAGGCGACAAATGCTGGCGGTGCAAGTGCCGATCCTAATGGACCACTCGCCGGGACAGCGACCATCTCAGTGTCGTCGTCTGCGGTCGGTACGTCCTCCATCAGTGCGGTCAGTGCGGTTTCGACGACGGCATCCACTACAACGACAACTACATTAACAACCGGCATCGGACAGGGTGGCGGTGTGCAGAATCAACCTGCCCAACAGCCTGCCGCCGCCACCGCCGCTACCACCAAGCTCGAGCAGAAGCCGGTCGAATGTAACCTGTGCCACCGGAAGTTCAAAAATATTCCCGCCCTCAACGGGCATATGCGATTGCACGGCGGTTACTTCAAGAAGGATTCGGAGGCAAAGAAATGTGATAAGAAGGAAAACACTGGGCCACCGCTACAGACAGCGAGCGTTGGTGTGCGGGCATTGATCGAGGAGAAGATCATCAATAAGCGCAGCAAGGATTTGAAGAATCTCTTATTGAAGGGTTCATTCGTCGTGCCGGCTCCACCGTTAACCGCCCGTCGGCTGATCGACGCCAACGAAGCATTCCTCTCACCGAAACCGAGCACGGTTGCAATCGTCTCCACGTCCAACGGTACTACCCAGATCATCAATACCGCCACGCTGCACTCCAAAGCCACGCTTATAAATGTCACCAGCTCACCACAGTCCATCAGCACCTCTTCGGCACCTTCCATAACGATCAATGGCTTGGCGACGGGTGCTACCACCACCACGGTTACCGGCACCGAACTCAAAGATGCTACATTAATCGAACTGCTCAAGCGCGGTACCAAGGTGGCGGTGAAACGGACAGCCTCCACAGGGGATACCTCCTCCACAGTGTTATCACTCCAGCAGTCCACGATCAATCCAACGATCTCCTCCGCGACCATCGCTAATCATGCAACGGCTCAGCTGATCACGTCTGCCAACTCTCGTACCGTTACCGTGCTGCCCGGTGCGACACTGTCCACAACGCCAAAGATGTCGCCCACGATCACTGGCACGAGTCTGATGACGAATCCCACCAACGATGGTACTCCACTGTCGTTAACCATATCGCAAACACCGACATCAGCACCAGGCGATGTGTTCACGCTGGCCTACTCTACCGACTTTGGTGATGGCGATGTGTACAGTGTAAGCGATACGGCCATGCTACTGCAAGCCGTCGACCCGATCCAGCTTCTGCAGGACTCAAACTCAACCGAACCGCTCGACGAGATCGCTCTCTCCGACTACGGCTCCATTAGTGATCAAGGATTTGCACCTTCGCGTCAAATACAGGCCGTGCTAGACTCTCCATTGCCGGAGGGACTGGCCGAGTTTGGAGCCCTGCACGGTAAAGACTTCAGTGTGTTATACGGTGGCACAACAACGTCCGGCGAAGTGAATGGAGGAACTTCTTCTGCCACCAATTTGCTTCAATCATCCCCGTCGGGATCTCATCTTTCACCGCTTCCCTCACCACTGGCCTATCCAACGCCTCCGGCCTCGCACGAGGCGGTAGCACAGGCATCGCCTTTTCTGGACGACTCGCGTCACTTCACCGACGCGGGCTCCTTCTTCGACGATAAGCGCGGTGCGCAAAGTTTCCTGGACGATGGCTTCTTCAAAACCGAGCCGAAGGACGATGAAACGAAAGTGTCCGACAGTGAGAAGATACTGGCGCTCAAGCATGAGCTGCTGGATGAAAATCACGACCTGTTCCGAGCAAACAAACACCTGCTGGATGAGCATTGTTCGGAGCTGTTCAAGACGGAGGATAGCTTTTTCGCCGAGTCCAAGCCCACCTCGGTGGATGGAACGTCCAAGATGAATCTGGACTTTCTGGACGATGCGCAGGTCTTTATCGAGGAGACGCGTAACGCATCGTCGCCCTTATCGAATGCATTCTTCTCCGCTACCATGTCATCGGCGGCGGAAGTGAAGGAGGCACTCGAAGAGGTATTACCCAACGATGATGACGACGATATTGGTGTGACGGAGGGTGATATCGATCTGTATTACCTTAATGGCCTTTCCTCGCTGCAGTCACAAATGATGCCCAATTCGGACGATCCATTACTGTCCTCGTCACCGAAAGACTTTGCCCACCGGCAGCATCAAAAGTTTCTCTTCGAACAGAGTCAAGCCGCTCAGCAGCAACAGCTACAGCAACATCAGCAACAGCTGCAGCAGCAACAACAATTACAACAACAGCAACAGCAGCAACTATTGCAACAACAGCAACAACAACAATCCGCCGGTGTTGGCGCAATCAACCAATGCATGCCTCCTAGTGCCAAAAAATCTAAACCCTCGGACGTTGACCCGAACACCTTTGGAGGTGATGCGAATAAGGTTCCCCTCACGGTACAAACCGATCCCATGCCAAAGGACGCGGACAGTGTGTTCCTCAGTCCGAGCAGTCTGTCCTCACACAGCTGTTCCTCTTCCTCGTCTTCATCCTCACTGTCGCTTTCCTCGGTAACTTCACCCAGACTGCAGCATGCGCTCCTGGGCAGTGCCAACTCTGGAGGACCTGTGTGGCCTCGCAAGCGCTCCCAATCATCAGCCACCGGTGCTGTGAACGTCTCCAGCCTTCCCGTCGGCCAGCGCAAACCAACCATCTATCTGTCCAAATTGCGGCGATCCACCACGTCGCTTCTGCCGGCATTACACTACACCCCTGCACCGATGCTAAACCCCGAACGTATCGGAACTACCGGATTGTACACGAACGTAACGCACGCTCGTTCCACCGGTGCCACGGACGTGGATCTCGACTCCACAATGGACAGCACGAGTGACATCTTTTCCGAGCCCCCATTACCGATACGTCCCCGTATTAACCTCGGCCCAGACTATCAAGCCATCGTACCGGAATGTACGCGACCGGTCTACAGTGGGCTGCAGCAGTTCCACGCGGCCCAGCAGGCCCAACGTCTCTGGGATCCGGCGTTAACTCCGAACGAGCGTCAAGTGCAACGTTTCATCGAGCTCGCACGTTCGTCCGCCGCTCCGTTGGGATGCCACTCGGAGGAGAATGCGCTGCGTGCTCTACTGGAAGCGAATGGTGAGATACACCAGGCCATTCTCGGTATGCTGCAGGGTCCGCCGGCCACCATACATCGCCGCTGGACGGCCGACGAAATCGAGCAGCTCATCCAGGGTCTCGAAGAGTACGGCAAAGACTTTCACCGAATCGCACGTGATTTGCTGCCCGGCAAATCGACTGCCGATTGTGTGCAGATGTACTACTTCTGGAAGAAGCTCGGAATCGACTACAAAGGTACGACGGCACTAGCCGGGCCCAAATACACCGGCATGCATGGTTCACCGTCCCCTACACCGTCACCACCGGCTCCACCGCCACCGGTAGAGGATCTACTGTTGGATCATCTGGACTATACGGCCAATACGGGCACAGGGACGACACTTGCCAGATCGCATCAGCCCGTTCAAACTGTCAATCTTCAGCAAAATGGCCACACCGTCAGTACGCCCAGTGATGTCCGACCGCATGTCTGCGAAGTTCCTGACTGTTCAGCGAGCTTCTCGTCCAAAGCGGCCCTCCACGGTCATATCCGCATACACTGCATCGGACGTAGCCACAGCACAGTTCAAAATGGGTATTCAATAAGGTAA
Protein Sequence: MAAVNSVQNSIRLPLAGLAPPRVLMCSASMGAEGSVTLQLREAVQAPDAAGSLDGALTIGYPDPEMLADMLGTFQGASTGATDSDAGSFDLLQDSNGSSAGATLRATAADQIEHLTGAILTKTSSSSGSSNTTGTSTVTIKTEPGTKPAAEKTNSTSNLLPNHTSSTTISSNNLSPSSTAILHHGTTMVTVKSSPNVGGSNGNIATAASPTSLVLTTVGRAETASGNSSSASSSPSAASSPGTVSLNGLSGGLAKKPRPKTVSPTRHGPQQCQVCSKVFGNASALAKHKLTHSDERKYVCGMCSKAFKRQDHLNGHMLTHRNKKPYECKAEGCGKSYCDARSLRRHTENHHSALGLANSSGTASPGPGGSNAGPPGGLSLSPATASGDASSPHGATLVQFTTTTTGNGTTGSSSSNSNCSLSSSSSSSSSSSSSSSSSSSSSSGNVSDSSSSCKSPSPSSPAPGSGNEGLTRQQLDLISQIMQQTKQANAAAAAAAAASSVSASGNGTGQLLTTSQKVPVRPRTWNMQLQLSQNKLSATTATTATTLTSAVASTTATVVSAVPVPSMAVGQTTTLSTSNAVNPTIISSHPNGTITTNIISKATNAGGASADPNGPLAGTATISVSSSAVGTSSISAVSAVSTTASTTTTTTLTTGIGQGGGVQNQPAQQPAAATAATTKLEQKPVECNLCHRKFKNIPALNGHMRLHGGYFKKDSEAKKCDKKENTGPPLQTASVGVRALIEEKIINKRSKDLKNLLLKGSFVVPAPPLTARRLIDANEAFLSPKPSTVAIVSTSNGTTQIINTATLHSKATLINVTSSPQSISTSSAPSITINGLATGATTTTVTGTELKDATLIELLKRGTKVAVKRTASTGDTSSTVLSLQQSTINPTISSATIANHATAQLITSANSRTVTVLPGATLSTTPKMSPTITGTSLMTNPTNDGTPLSLTISQTPTSAPGDVFTLAYSTDFGDGDVYSVSDTAMLLQAVDPIQLLQDSNSTEPLDEIALSDYGSISDQGFAPSRQIQAVLDSPLPEGLAEFGALHGKDFSVLYGGTTTSGEVNGGTSSATNLLQSSPSGSHLSPLPSPLAYPTPPASHEAVAQASPFLDDSRHFTDAGSFFDDKRGAQSFLDDGFFKTEPKDDETKVSDSEKILALKHELLDENHDLFRANKHLLDEHCSELFKTEDSFFAESKPTSVDGTSKMNLDFLDDAQVFIEETRNASSPLSNAFFSATMSSAAEVKEALEEVLPNDDDDDIGVTEGDIDLYYLNGLSSLQSQMMPNSDDPLLSSSPKDFAHRQHQKFLFEQSQAAQQQQLQQHQQQLQQQQQLQQQQQQQLLQQQQQQQSAGVGAINQCMPPSAKKSKPSDVDPNTFGGDANKVPLTVQTDPMPKDADSVFLSPSSLSSHSCSSSSSSSSLSLSSVTSPRLQHALLGSANSGGPVWPRKRSQSSATGAVNVSSLPVGQRKPTIYLSKLRRSTTSLLPALHYTPAPMLNPERIGTTGLYTNVTHARSTGATDVDLDSTMDSTSDIFSEPPLPIRPRINLGPDYQAIVPECTRPVYSGLQQFHAAQQAQRLWDPALTPNERQVQRFIELARSSAAPLGCHSEENALRALLEANGEIHQAILGMLQGPPATIHRRWTADEIEQLIQGLEEYGKDFHRIARDLLPGKSTADCVQMYYFWKKLGIDYKGTTALAGPKYTGMHGSPSPTPSPPAPPPPVEDLLLDHLDYTANTGTGTTLARSHQPVQTVNLQQNGHTVSTPSDVRPHVCEVPDCSASFSSKAALHGHIRIHCIGRSHSTVQNGYSIR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00103982;
90% Identity: iTF_00105385;
80% Identity: iTF_00101621;