Basic Information

Insect: Anopheles funestus
Gene Symbol: -
Assembly: None
Location: Contig0:86541224-86543566[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.018 1.1 9.6 0.2 1 23 263 287 263 287 0.95

2 9 0.12 7.4 7.0 8.1 1 20 292 311 292 314 0.93

3 9 0.00025 0.015 15.4 3.2 1 23 320 342 320 342 0.96

4 9 1.2e-06 7.2e-05 22.8 2.6 1 23 348 370 348 370 0.95

5 9 0.00069 0.042 14.1 2.7 2 23 377 398 376 398 0.97

6 9 8.5e-05 0.0052 16.9 2.4 1 23 404 426 404 426 0.98

7 9 1.3e-05 0.00076 19.5 5.6 1 23 432 454 432 454 0.99

8 9 1.9e-06 0.00011 22.1 1.9 1 23 460 482 460 482 0.98

9 9 0.00021 0.013 15.7 1.0 1 23 488 510 488 510 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.018	1.1	9.6	0.2	1	23	263	287	263	287	0.95
2	9	0.12	7.4	7.0	8.1	1	20	292	311	292	314	0.93
3	9	0.00025	0.015	15.4	3.2	1	23	320	342	320	342	0.96
4	9	1.2e-06	7.2e-05	22.8	2.6	1	23	348	370	348	370	0.95
5	9	0.00069	0.042	14.1	2.7	2	23	377	398	376	398	0.97
6	9	8.5e-05	0.0052	16.9	2.4	1	23	404	426	404	426	0.98
7	9	1.3e-05	0.00076	19.5	5.6	1	23	432	454	432	454	0.99
8	9	1.9e-06	0.00011	22.1	1.9	1	23	460	482	460	482	0.98
9	9	0.00021	0.013	15.7	1.0	1	23	488	510	488	510	0.98

Sequence Information

Coding Sequence: ATGGAGGAAGAGTTTTTGACTATTGCTATGAAACCGACGCTTTGTCGTATTTGTGCTGTATTATGTCCCGAACAATACTGTATCTATGAAGCTGTGTACAAGGATGAAGCAATAAGCATGCATATGATGATGGAAAAGTTGGTTCCCTCCGTGTTCAATACGGAGCAAGTGAAGATGGATGAGTTCATGTGCTGGCCAAGAAAAATTTGTGCAGATTGTAAGGACAAGGTTCTGGGTGCGTATGCTTTATACGAGCAGTGCATGAAAAGTGGCGATCTTCTGAGAGAATGTATGTCCCGAAAAACCGAATCATACATAATCGAAGATGTGTACGAGGATGTGAAGCAAAACTTTGTTCTTGATAGTTCTCTTGAGCTGGCATCCAACTATGAAGATGATGAAACGAGCGAACCAACGCAATTAGCTCAAAGACCAACGCTTAAGAGGGCTGCCCGAAAATGGCATATCGTGGAAAGCACGCAGCAGGATATTTCATCGTTTAATATAAAATCCGATGTGATAGAAGACCGTTCCCCCACACCAACGGAAGATTACGAGCTACACACAGATGATGAAGATGATGAACAACAATCCCATAGCGCGTCCACATCAAGTAAAAAAGTTTCACGCAATACTTCCGCACGACAACGAAAGGCATCGAAGCGTGGTTCTGCCGCTGGCAAGGAAAAACCGCAGAGAAATCAAGCAAGGGCTAAGCGAAAGGTGCAAGAACCTAAAGAAGACATTTCGGACGAAACGAAGGAACCGGAAACCAAGGTAGATACATACCGCTGTCTGCTTTGCAATGCGCCGACCTACTCCTCGCCGAAAGAACTTACGGAGCACTTGAAAACGGAACATCCCGATCAGATTCACTGTTGCACACAGTGTCCGAAGGTGTTCATGACCAAAGCGGCCTTTGAGCATCACCAGTACTGTCACGCTACTGGCCGATCGCATTTCTGCATGTTTTGCGACAAAGGGTTTCAAACGGAGCAGCTGCTTAAGAATCACATACGAACGCACACCCATGGTACAGGCTTTTTGTGCTCCCATTGCGGTCAAGAGTTTAGCAACAGAAGCAACCTTCGACAGCATCTGATTCGTCATACTGGCGATAAACCATGGCAATGTACCTTATGCCCGAGCCGCTTCAGCATGAAAAGTTATTTAGACAGACATCAACATACACATACGAAAGCTAAATACTTCAGCTGCGACACGTGTGGATCTCAATTTAGCAGACATTACTCATTAGTAAAACACCAGCTCATCCATACGGGCGATCGCTACTTTACCTGTGAGGTTTGCAATATGAGATTCACCTCAAGCCATCACGTAAAGCGTCACATGCTTACGCACACGGGAGAAAAACCATTCAAATGCACTTACTGCGAGCGTAGCTTTACGCAAAGCAATGATATGGTGAAGCATATGAAAGCGCACGTTGGTAGCAATCCGTACCAGTGCGATCGTTGCGATGCATCTTTCCGGCTGCTCACGGATCTACGGAATCACTACAAGGACCATTATCAGTCGGGCAACAAAGAGGCACTTTCAGGCGAGGAGGATAAAAACATACGCTTTACAAGCACAAATATTTTGAAAATTCGATACGAGAAGGAAATGAACCAGTCTGCCGACAAGAGCATACCAGATAAACTTAGCGCATAA
Protein Sequence: MEEEFLTIAMKPTLCRICAVLCPEQYCIYEAVYKDEAISMHMMMEKLVPSVFNTEQVKMDEFMCWPRKICADCKDKVLGAYALYEQCMKSGDLLRECMSRKTESYIIEDVYEDVKQNFVLDSSLELASNYEDDETSEPTQLAQRPTLKRAARKWHIVESTQQDISSFNIKSDVIEDRSPTPTEDYELHTDDEDDEQQSHSASTSSKKVSRNTSARQRKASKRGSAAGKEKPQRNQARAKRKVQEPKEDISDETKEPETKVDTYRCLLCNAPTYSSPKELTEHLKTEHPDQIHCCTQCPKVFMTKAAFEHHQYCHATGRSHFCMFCDKGFQTEQLLKNHIRTHTHGTGFLCSHCGQEFSNRSNLRQHLIRHTGDKPWQCTLCPSRFSMKSYLDRHQHTHTKAKYFSCDTCGSQFSRHYSLVKHQLIHTGDRYFTCEVCNMRFTSSHHVKRHMLTHTGEKPFKCTYCERSFTQSNDMVKHMKAHVGSNPYQCDRCDASFRLLTDLRNHYKDHYQSGNKEALSGEEDKNIRFTSTNILKIRYEKEMNQSADKSIPDKLSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00105336;
90% Identity: iTF_00101859;
80% Identity: -