Afun004595.1
Basic Information
- Insect
- Anopheles funestus
- Gene Symbol
- zfy1_1
- Assembly
- None
- Location
- Contig1:70981425-70984445[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 1.1e-05 0.00068 19.7 1.3 1 23 12 34 12 34 0.99 2 13 2.7e-05 0.0016 18.5 2.8 1 23 40 62 40 62 0.97 3 13 1.9e-05 0.0011 19.0 1.6 1 23 68 90 68 90 0.97 4 13 0.00058 0.035 14.3 7.0 1 23 135 158 135 158 0.95 5 13 0.0023 0.14 12.4 1.9 1 23 164 186 164 186 0.98 6 13 1.4e-05 0.00086 19.4 1.0 1 23 192 214 192 214 0.98 7 13 0.00038 0.023 14.9 1.8 1 23 220 244 220 244 0.95 8 13 0.58 35 4.9 0.5 2 23 600 621 599 621 0.93 9 13 0.0017 0.1 12.8 0.4 3 23 661 681 659 681 0.96 10 13 3.9e-06 0.00023 21.1 2.2 1 23 686 708 686 708 0.98 11 13 1.6e-05 0.00099 19.2 1.3 1 23 716 738 716 738 0.99 12 13 0.029 1.8 9.0 7.7 1 23 744 766 744 766 0.96 13 13 0.012 0.75 10.1 0.6 2 23 773 795 772 795 0.90
Sequence Information
- Coding Sequence
- ATGCGTATCCACTATCACGAACAGATGGGAACATTCAAATGTCAGTATTGCGAACGTGTTTTTGGTACACGAGCACGGTTGGAGCGTCACGAACGAACACATACCGGAGAACGACCGTTTGCATGTCATCTGTGCACGAAAACGTTCGCCCACTCGGGACAGCTAGCGACGCACATATCGCGACATAATAATGAACGCGGTCACAAGTGTGCCCAGTGTGGAAAAGCGTTCTTCAACAAGGCAATGTTGCGACAGCACCTAGAGTCGCATGGAACGGTTGAATCACGAAAAGCTACCAGCACGGTTAAAATGCGGCAACGACCCTGTACGTATCCTGGCTGTGCGCACGTGGCACTAACGTATCAGGCTTACTACTTGCATCGACTCCGGCACGAAATGGCCCACCGATGTGAGGAATGCGGTAGACGCTTTGCTCGATATTGTGAGTTGCGACGCCATCGGCATATCTACCATTCGACGGAACAGCCGTTCAAATGTGAACTGTGCAGTAAAACGTTCCTTAGCTCGCAAAGCTACCGGGAGCATATGGATTCGCACGCGAACGTACGCCGCTTCGAATGTGATGCTTGCGATAAAAAGTTTGTGCGTCGTCGCAATCTGGTGAACCACCGAATGTCTCACACTAACATTCGTCCGTACCGGTGCGAAGATTGCGACAGCGCGACGTTTAAGTACAAGAGCGATTTAAACCGACATCGGAAAGATAAGCATGAACAGACGGAGCAGGAGGTTGATGGGCCGATGCAAATAGATGGCGAATCTGTTAACGAACAGATTGTGCTGATGAATGAGGATCCCGTAATGGATGGTATGATCGTAGAAAGTGTACCCGAGGGCATATTGGTGAATGAGGGTATTGAGCTAGATGGAACTTACGGTGAGGTTATAGAAACGGTGGAAGAATCCATTGTCGTTGAGCAGCCAATAGTTAGCTTCGTGACGACCGATGCGTTTTGTCGAATATGTTTGATAAAATCCACCCAGCTGAAGCCCTTACTGGAACGTGTGGATGGGATAATGATACCGGAAATGCTCTACAAGCTGTGCGGTCGCCAGATTGAGGTCCAGGAAGGCTATCCGCGCAGCATCTGCGAACAGTGTTTTTGTAAGTTGGATTGTGCGTTCCGGTTTTTGAACGAGTTTCACCAGCAGGACGAACGTTTGCGCAGCTTTTATTGGAGTGGGTCCGTAGGGAAAAGGTTGCAGGAATATCAAGCAGAGGGCAGCGCAACTGTTCAGCAGCAAACGGATGAGTTGATCAACCGGTACAAGTTTCTTTTCAATCAGCCTACTAAGGAGATGTGTCATAAAGAGACCAACACAGCAAAGCAGAAGCAACCGAAAATGGTCGACGCTAGTACGATTACGGATAAGGAGATGCTTAATCTTCAACTTATCAAAACTGAAGAAGAAACGGATGATGAGATACTGCTGGAACATTACGTTATGGAAGAGGACAACGATGAAACGTATATCGATTACAGCTTGGATAGCGAATCAACGCTGAAGGATGAACAGTTGGGGGAGATGAAAATAGATTTGCTCGGCAGTCAGTCGGCGGACGAAGCAGAATCGTACACGGACGAAAAGCCCTTTAGAATAAACCTGACCAAAGGCACTAGACAGTCTCCGCGCCCCAAAGAAACAATGGTTAAGTTAGTGTCGCCCAACCTGAAGGAGGAAAGCATGCCGACCGATACAGATGACCAGTCACAAGAACCGATATATTACGAGGAAACGGAAACAGAGGAGGAAGAGGAATCGTTCGATCCACTTCGGTGTTGCATTTGCGACAAACGAGAGGAAAGTGAAGAACTGTTGGAGCAGCATCTCGATCTACACAGCACCATGCTGCCGTACGATTGCAAAACGTGCCTTGCGCGCGGGGCACAGGTCCGCACGATCAAGACGGTTTCCTCGCTGCACAATCACTTTCGCTCGCACCATTACCCGTACTGGTGCGAAGTTTGTGGTAAGCGCTTCCTGCGCAAAATACAGCTGGCAAAGCATAGGGAAAACCATTCGAATAGCTTGTTCGTTTGTGACGAATGTGGTCGCGGTTTTACGCATAAGAAAACGTGGCAAAATCACATCAAACGACACAAGGCGATGCGTGCAGAGGTGTACAAATGTACCACGTGCAGTAAAGCCTTCGGCAACAAGGCCCGGTTGGATCGGCACATGCGCTTGCATACCGGTGATCGGCCCTTCGAGTGCAAGTACTGTGATAAGCGGTACTATGACCGCCATCAACTGCAGTGCCACACGGAAAAGCACTTCCGCGATATGGATTGTCCGTGCGAATACTGTGGCGAAACGTTCGCGGGCACGAGGAAGCTCGATGCACATAAGATGGCGAAGCATCTGACCGGCAAGGAGCTAGAAGACTTTAAGGCCAACCGTGCGAAGCGGGTTAAAACGGCCCGCTTTGCTAGATGA
- Protein Sequence
- MRIHYHEQMGTFKCQYCERVFGTRARLERHERTHTGERPFACHLCTKTFAHSGQLATHISRHNNERGHKCAQCGKAFFNKAMLRQHLESHGTVESRKATSTVKMRQRPCTYPGCAHVALTYQAYYLHRLRHEMAHRCEECGRRFARYCELRRHRHIYHSTEQPFKCELCSKTFLSSQSYREHMDSHANVRRFECDACDKKFVRRRNLVNHRMSHTNIRPYRCEDCDSATFKYKSDLNRHRKDKHEQTEQEVDGPMQIDGESVNEQIVLMNEDPVMDGMIVESVPEGILVNEGIELDGTYGEVIETVEESIVVEQPIVSFVTTDAFCRICLIKSTQLKPLLERVDGIMIPEMLYKLCGRQIEVQEGYPRSICEQCFCKLDCAFRFLNEFHQQDERLRSFYWSGSVGKRLQEYQAEGSATVQQQTDELINRYKFLFNQPTKEMCHKETNTAKQKQPKMVDASTITDKEMLNLQLIKTEEETDDEILLEHYVMEEDNDETYIDYSLDSESTLKDEQLGEMKIDLLGSQSADEAESYTDEKPFRINLTKGTRQSPRPKETMVKLVSPNLKEESMPTDTDDQSQEPIYYEETETEEEEESFDPLRCCICDKREESEELLEQHLDLHSTMLPYDCKTCLARGAQVRTIKTVSSLHNHFRSHHYPYWCEVCGKRFLRKIQLAKHRENHSNSLFVCDECGRGFTHKKTWQNHIKRHKAMRAEVYKCTTCSKAFGNKARLDRHMRLHTGDRPFECKYCDKRYYDRHQLQCHTEKHFRDMDCPCEYCGETFAGTRKLDAHKMAKHLTGKELEDFKANRAKRVKTARFAR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -