Basic Information

Insect: Anopheles funestus
Gene Symbol: -
Assembly: None
Location: Contig1:52749308-52760240[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 3.9e-05 0.0024 18.0 0.4 2 23 99 121 98 121 0.96

2 14 0.16 9.6 6.6 3.7 1 19 129 147 129 152 0.91

3 14 4.2e-06 0.00025 21.1 4.2 1 23 158 180 158 180 0.98

4 14 3.5 2.1e+02 2.4 0.4 1 23 183 206 183 206 0.84

5 14 0.81 49 4.4 4.7 1 23 211 234 211 234 0.97

6 14 5.5 3.3e+02 1.8 3.4 1 23 241 267 241 267 0.90

7 14 0.00094 0.057 13.6 0.8 1 23 385 408 385 408 0.91

8 14 1.1e-06 6.8e-05 22.8 0.7 2 23 414 435 413 435 0.96

9 14 0.00068 0.042 14.1 5.9 1 21 475 495 475 496 0.94

10 14 0.00013 0.0082 16.3 1.3 2 23 555 576 554 576 0.96

11 14 1.1e-05 0.00069 19.7 1.1 1 23 582 605 582 605 0.96

12 14 1.6e-07 9.6e-06 25.5 5.1 1 23 611 634 611 634 0.98

13 14 0.0002 0.012 15.7 0.4 1 23 640 663 640 663 0.91

14 14 0.00029 0.017 15.3 0.8 1 22 668 689 668 692 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	3.9e-05	0.0024	18.0	0.4	2	23	99	121	98	121	0.96
2	14	0.16	9.6	6.6	3.7	1	19	129	147	129	152	0.91
3	14	4.2e-06	0.00025	21.1	4.2	1	23	158	180	158	180	0.98
4	14	3.5	2.1e+02	2.4	0.4	1	23	183	206	183	206	0.84
5	14	0.81	49	4.4	4.7	1	23	211	234	211	234	0.97
6	14	5.5	3.3e+02	1.8	3.4	1	23	241	267	241	267	0.90
7	14	0.00094	0.057	13.6	0.8	1	23	385	408	385	408	0.91
8	14	1.1e-06	6.8e-05	22.8	0.7	2	23	414	435	413	435	0.96
9	14	0.00068	0.042	14.1	5.9	1	21	475	495	475	496	0.94
10	14	0.00013	0.0082	16.3	1.3	2	23	555	576	554	576	0.96
11	14	1.1e-05	0.00069	19.7	1.1	1	23	582	605	582	605	0.96
12	14	1.6e-07	9.6e-06	25.5	5.1	1	23	611	634	611	634	0.98
13	14	0.0002	0.012	15.7	0.4	1	23	640	663	640	663	0.91
14	14	0.00029	0.017	15.3	0.8	1	22	668	689	668	692	0.89

Sequence Information

Coding Sequence: ATGGAGCAACTGCATCGTGCATTTCGATGCCATTGCTGCAACGAATTCTCCGACGATTGGAGAAAACTTGAAACCAGCGTGATGACGATGGGAAAAGCTGTTTTAATTCGCGATATGATCGACATTTTTCGGCTTCCACAGGGTTGGAGTATTAAAAAGAACGATGCGATATGTTTTGCTTGCCTGGAACGGCTCGAATATTGCTACCAATTCTATGCAACGTTACTAAACACAACGGCCAAAGAAAGTAATAATTCCAATGATCAAACTCCCACGGAAGCAGATACCGTTGTGCAATGTTCCTTCTGTGATATTTCGTTTGTTACCAAGGTGGATTTTGAAAAACATTTAAAAATACAACATTCTCAGTCAACACATCAATTCTACTATTGCCAAGCATGTAAAAAAACATTTAAAACCAACCGTGGCATGCTTCAGCATTGTACAATCTACCACGATGCTCAGGAAAAATACGTATGCCACATTTGCGAACGACAGTTTATCACTAAAACCAACTATCGGAACCACATGCGTTATCACAAAGATCATGTGTGCGGCTTTTGTAACAGCGGATGGATGGACGAGACCAACCTGTTGGAACATGTGCGTACTACGCACAAGGATCGTTTGTTCGTTTGTCGGTTTTGCAACCGAAAGGAAAGGCTGAAGAAGTGTCTCAACCGACATCTACGTTCAGCCCATCAGCAGGAATCGAATCCATATTTCTGTGGTCACTGTGGGCAGGAAAATTGTTTCTACGAGAGCTACGAAATGCTTACGAACCATTTACAGCAACAACATCGCGAAGACGCCGGAAACGTTCACGGGAAAGATTCATACGGGACCTTGTTGAATGATTCCTTGCTTGCGAAAGAGTTTGAGCTTCAAGAAATGAATGTAATTGGTAAAGAACAGGAGCAATTTTTGCAAAATTTAAATTTGCGGAGGAGCGGCAATGAAAAAAAGGAAATTTCTCGCCCGTTGGAACCAAGAATCGATCAAAGGATGATTCTGGAAGATTTTCTCGACGAAGCGTTCGAGAATGACGAGATCTGGAATAAGTACATCGAAAACGGGGAAGAGTATTTGATCGATGATTATGATTTCTATTTGAAGGGAATTGAAGGCACCACGGAACAAGAATTGTGCATGTATTTATGTCCACAATGTCAGCGAGGATTTCAAAAGCAAAATCATTTAACAGTTCACCTGGCCGAGGACCATAACGTGCCCAGCCTGGTGTGCAACGATTGTGGAGCTAGCTTTACTCGCTTATCAAACTATAGAACTCATCGACGGGAGCATCTGAAAGACAATGTTCGTTTTCGCGAAAGCAACATTCCCGAAATGGAGGAAGCTCTGTCACTCGTGCAAAGCACATCGCTGGGCTACTCGGTACATGAAGAAGATGGTGGTTACATTTTCACATGCAATTTGTGCGACCGCAACTTCCAACGGAAGCACAATCTTGAAAAGCACAAATGTCGATTCTACGATCGTCACCAACAGCAGACATCTACAGATGGACAATGTATTGAGGAATCCGAACACGATCCTTGCTCAATTTCTCTCCTCCAAACGACATCAAGCACTGAGATGGACACAATTCAACGCACGCATCGATCAAACATTGGAGCACCGGAACGTAAGCAGGAAGTCATCTACTGTATGCTATGCGATCGCCGATTTAGCTCCACCTCTGGTTTGAAATATCATCTAAAGCGACACACGGGTATTAAAGCGTTTGCGTGCCTGTACTGTGAGAAAAGGTTTACAGCAAACTCGAACCTGCACGCTCATATTCGAAATGTGCATAGCGAGAGAAAGGATTTTCGTTGTACCGATTGCAACGAAACGTTCACTACTAAAGATCATCTCAATAAGCATCAACGATCTCGGCATCGCCAGGATCGTGCTTTCGTTTGTGGTGAGTGCGGTAAAAGCTACTTGCAAAAATCACATTTGAACGAGCATGTAGCAGCGAGTCACCGAGAAGATCGCTACTTGTGCAACGTTTGCAACGGCTCTTACGCTAGTAAAAGTTCTTTGAAACGTCATCAGGCTAGGCAGAAGCATTACATTCAGCAAGAAGAAAATATATGA
Protein Sequence: MEQLHRAFRCHCCNEFSDDWRKLETSVMTMGKAVLIRDMIDIFRLPQGWSIKKNDAICFACLERLEYCYQFYATLLNTTAKESNNSNDQTPTEADTVVQCSFCDISFVTKVDFEKHLKIQHSQSTHQFYYCQACKKTFKTNRGMLQHCTIYHDAQEKYVCHICERQFITKTNYRNHMRYHKDHVCGFCNSGWMDETNLLEHVRTTHKDRLFVCRFCNRKERLKKCLNRHLRSAHQQESNPYFCGHCGQENCFYESYEMLTNHLQQQHREDAGNVHGKDSYGTLLNDSLLAKEFELQEMNVIGKEQEQFLQNLNLRRSGNEKKEISRPLEPRIDQRMILEDFLDEAFENDEIWNKYIENGEEYLIDDYDFYLKGIEGTTEQELCMYLCPQCQRGFQKQNHLTVHLAEDHNVPSLVCNDCGASFTRLSNYRTHRREHLKDNVRFRESNIPEMEEALSLVQSTSLGYSVHEEDGGYIFTCNLCDRNFQRKHNLEKHKCRFYDRHQQQTSTDGQCIEESEHDPCSISLLQTTSSTEMDTIQRTHRSNIGAPERKQEVIYCMLCDRRFSSTSGLKYHLKRHTGIKAFACLYCEKRFTANSNLHAHIRNVHSERKDFRCTDCNETFTTKDHLNKHQRSRHRQDRAFVCGECGKSYLQKSHLNEHVAASHREDRYLCNVCNGSYASKSSLKRHQARQKHYIQQEENI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -