Afun004934.1
Basic Information
- Insect
- Anopheles funestus
- Gene Symbol
- -
- Assembly
- None
- Location
- Contig1:40035283-40042192[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 25 0.00085 0.052 13.8 1.6 2 23 408 429 407 429 0.97 2 25 0.0021 0.13 12.5 1.4 3 23 437 457 436 457 0.98 3 25 0.092 5.6 7.4 1.4 1 23 467 489 467 489 0.96 4 25 2.1 1.3e+02 3.1 0.0 3 23 514 541 512 541 0.75 5 25 0.81 49 4.4 1.3 2 23 548 569 547 569 0.89 6 25 2 1.2e+02 3.2 0.4 1 23 575 595 575 595 0.85 7 25 6.2e-05 0.0038 17.4 0.4 1 20 607 626 607 627 0.97 8 25 0.0034 0.21 11.9 0.6 2 23 636 657 635 657 0.97 9 25 1.8e-05 0.0011 19.1 0.6 1 23 662 684 662 684 0.97 10 25 8.5 5.1e+02 1.2 0.6 3 23 694 714 693 714 0.90 11 25 0.00062 0.038 14.2 2.7 3 21 722 740 721 741 0.95 12 25 0.0031 0.19 12.0 3.1 1 23 752 774 752 774 0.98 13 25 0.00091 0.055 13.7 2.5 1 23 780 803 780 803 0.98 14 25 0.0012 0.072 13.3 3.5 2 23 1205 1226 1204 1226 0.97 15 25 2 1.2e+02 3.2 4.1 2 23 1233 1254 1232 1254 0.93 16 25 0.012 0.72 10.2 0.6 1 23 1264 1286 1264 1286 0.96 17 25 0.085 5.2 7.5 0.0 3 23 1311 1338 1309 1338 0.86 18 25 2.3 1.4e+02 3.0 0.1 2 23 1345 1366 1344 1366 0.95 19 25 0.00016 0.0096 16.1 0.6 1 20 1405 1424 1405 1425 0.96 20 25 0.006 0.36 11.1 1.2 2 23 1434 1455 1433 1455 0.96 21 25 0.0014 0.086 13.1 2.3 2 23 1461 1482 1460 1482 0.92 22 25 0.14 8.3 6.8 0.9 2 23 1491 1512 1490 1512 0.96 23 25 6.4e-05 0.0039 17.3 1.3 3 21 1520 1538 1518 1539 0.94 24 25 2e-05 0.0012 18.9 0.5 1 23 1550 1572 1550 1572 0.99 25 25 0.00091 0.055 13.7 2.5 1 23 1578 1601 1578 1601 0.98
Sequence Information
- Coding Sequence
- ATGGCGCACAGCAACAATTGTGCGCTTTGTTTTACAAACGATTCAAAGTGGTTTATGGAAGTGTTTAGTGACGCTAACAGTGAGCTGGATATGGCTTCGATCATATCAAAACACCTATGGTTTGAACTTAAACCAGCAGAAAATCCGCAGGTGTGTAACGAATGCTGGACAAGTTTACACGATTTTCATCTGTTTTACACCACGCTGGCAGGCATTCATAGTGCGGATATCGAGGGAAATGACACGATAGAGCAGCAAACGGAAAAATCTGAGTTGTTCGGAGCTATTGAAAGAGACCCTTTCCGAGAAAACGATAATGAGCCAGAGCCAGATCGTGAGGTAAAGCCTGTAACAGGAAAAATATCGGCCAGAGTTACTAACCCACCCATCACATACGAAACTGAAGCTGGGCCGTCGAGCAAAGATGAAAAGAAACACTTTGTCGAGGTCATTGATTATGTTAGCAACGATGAAGATTTTGACGACTTCTACCAGTCAGAGGACAATATGCTCGACGATGACACTCTTAACATCGACTACAAGGAAAATGCTCTAACGGAAGAGTCAACACAAATCGATGCAAATGATATTACAATGGTTGAAGAAGAACCACCAAAACGTCGTAGTGGTCGTCCATCGAAAATAAAACTCGAGCAGGACGTGAGTCCAACGGAAGCACTTAAAGAACCACGTACAACCGTTTCGACAGCAACGCCAAAACGACCTAGAGGCCGCCCTCCGAAGCAAACCCCGAATGCACAAAGCACAAAGGAAGCAAATGATATCGGCGTCAAAGAAGAGAAATCACCACTCCAAACAACATCCACCGCCGCACCTTTACCGATCAAACGTGGTAGAGGTCGGCCACCGAAAAGAAGGCTAGAAGCTTCAACCGCAGATTATAAGCTGCGTTCTGGTATAAAAATCGAAGTTAGTGAAGAAAATTCCCCCCACACGATAGCAGATAGCACTAAAAAGAAAACAATTCGTGCTCGGAAACCAACACCAGAAAGGGAAAGCGAACAGGACGATATTTCAGATGATGAAGAATGGCAGGTGAACAAGAACGTCACAAAACGCTTTAGAAAGGATCGAGATGAGCGAATATTCAAGTACGTGGATGAATTTAGCTGTTACTACTGTATTGACCACGTGACCTTTAAACGCTTTATTGAAGCGAACCGACATTACAAGCTGGTGCACCAGGAGTCAGCCTTCTTGAAGTGTACGATATGTGAGAAGAAATGTTATACACCCGGCATGTTTGTAAGCCACATGGAAACGCACGAAGATCCGGCGAAAAATATATGTACCATTTGTGGAAAAGTTACGGACTGTAACATCTCGCTTAAGAAGCATATGCGCGTCCATTCACGCCAGCTGGAGCAGAACTTACCGTTTCCCTGCAGCAGCTGCAAACGAAGGTTCGAATCGGAGGAGTTGCGAAACAAGCACGAAAAATTGCACGTTCCAAAACCGCTCGTTAAGCGTGACAAGGGACCGGATCTGGAAGTGCTTGCCTTCTACAAACGCATCTATTGTGATGTTTGCGAAGAGGCGACACCTAATTCGACTTCGTTCGAAAACTTCTGGGACCTTCGAGTGCACATGGAGCAGGAGCACAACAAGAATGCGTACCTTAAATGTCCCATTTGTAACAAGAGAAACCTTTACCGGCAGCACCTGATCACGCATATAGACATGCACAATAATCCGGAGAAATATCGATGTGAAGTTTGTAAAGAAATTTACCAGAACCTTGATACGCACATGATTAAGGCGCATACACCCACCACGGCGATACCAGCGGACAAAAAGTACAAGTGTGACCAGTGTGGCAGAATGTTCAACTACTTGGCCCACTTAAAAATTCACATCGATTGCATTCACGGTTCGAAAGATGTCCGCTGCAACGTTTGCGATAAGTATTTCAATCTGAAAGCTTACCAAGTGCATAGGCGAACGGCGCACACGGACAAGATGTTCATATGCGAACAGTGTCCAAAGATGTTCAGAACACGTGGCTCATTGGAAGTGCATAAAACCACTCACGATTCAACCTCGGTGCAGTTTAAGCCCTGCAAGCTGTGCAACAAGCAAATACGAATTACAAACATCTATAAGCACATGGTAACGCAACACTCCCAGGATGGACCGGCGAACTGTGAGCTGTGCGGCAAAACGTTCCGCACCATGTTCCACATGAAGCGGCACCAGAAGAATACGTGCGAAGCAACGATCAACTCGCGCAAGCACAAATGTGAAGTGTGCGGCAAAGGATTCTGCTTGAAGCTGACGATGATCGAGCATATGACGACGCATACGCGTTCGAACAAGTATCAGTGTGCATTTTGCTTCAAATCGTTTGGCTATATCTCTAATTTGTACAAACATCGGAAGAAGGCACATCCGCAGGAATGGCAGGACATACTGGCACGTCCCGAGGAGGGCATAGCATCGGTTATTGTTTTACACCAAGATACCGATCCGTACATCTGTATCGATTGTTGGACCGCTGTGAATGAATTTCATCTGTACTACACCAGGCTGGAAACCATCCATAACGAAGGTTTGGATAATACGTCGGTAACGGCTTACGATGCTAGCGAGCTGAAGAATATTGAATTCCTTGAGGAAGACGCCGACGAGCTGCTGCAGTTAACACAAGCATCCTTCGACGAAACTCGCGCAGAGCATGAAATTAATGTTAAAGGAGCTTTGAATTCTGCTCAGAAGCATAAAACCAGCCCGAAATATTCGAAACAGAGCGACACTAAAGGTGTAATCGAGTTAGATGGATACCGAATTGTCAAAATTGAAGTGGATGGTGCTGAAGACGACGATGGTACACTGTACGACACGGATGATGATCAAAGCGATCCGGAAGCTCCGGATCGAAGTACCAAGCCAGTGATATTGAACGGTAGAACGAAAGCCAATGTTGCTAGTGAAAGTTCGACGATTGCTATCGACATCCTGGAGGAACCGCCAGTGAAGCGTGGTAGAGGCCGTCCTCCAAAGCGGAAACCTGAACAGCAGCAATTTGAAGGGCACAACGCGAAGATAAAGAGGGATCTAGATGAATCTGGTGCGTCTATAGATTCAACAGGTGGAGACATAGTGGATGAGCCCGTGAAGCGTCGCAGGGGTCGGCCACCGAAGAACGCTAATGCACTGCACAACGTATCGAACACAACACCGCGCATGGTTAAGAAGGAGATAAAATCGGATAGTACCGACGAGGTAACGCCCGACCGCTACACATCATCTCGTCCGGAAAGAAGATCGACACGTGTGCGCAAAGTCAAGCGCTACAGCGATATGGAGCCGGCGAGTGATGAGGAAAGTGAAGTGCAGGATACACAATACATACTGAGCGAAGATCCGGATTACGAAGCGAAACTGGAGCTGCAGAAGCAACTAAACATGGATGATTTTGCCTTTTACGAGTATCAGTGCAGCTTGGAGTCGGAGCAGGTTGCGCGCGATAACAAGATATTCCAGTACGTGGATGAGTTCGCTTGCTATCTGTGTTCGGAAAAGGTCACGTTTAAGCGGTTTGCCGACGCGCATCTGCACTATCGCGTGGAGCACAATCAGCCGCCATTTTTGAAATGTCCAAAGTGTGACAAAAAGTGTCACACGCCGGGTATGTTCGTAAGTCACATGGAAACGCACGACGATCCGGAAAAGAACAAGTGCGAAATTTGCGGAAAGTACAACGATTGTAACATTTCACTTAAAAAGCATATGCGCGTACATCAGAGCCAGTTGGAAGAGAATCTACCGTACCCGTGCAGTCTCTGTAAGCGGAAGTTCGCGACGGAAGATCTGCGAGCGAAGCACGAAAAGCTGCACGTACCAAAGCCTTACGTACCGAAGGAAAAGGGTCCCGATCAGGAGGTGCTCGATTTCTACAAATGTATCGTGTGCGATATATGCGAGGAAGAGACACCCGATTCTACGTCGTTCGACAACTTGAGCGACCTGCGGGCGCACATGGTAAAGGAGCACAACAAGAACATGTACGTGCGGTGTCCGGTGTGCTCTACGAGACAGGCAAACCGTCAGCAGGTCATCACGCACATTGACATGCACAATAATCCCGATAAGTATCGGTGTGAGCTTTGTAACGAAGTGCACCAGAACCTGCACCATCATATGCTGAAGGCACATTCCCCTAGTACAGCCCAATCATCCGATAGCGCAAAGCACAAGTGTGAACAGTGTGGTAGAACGTTTAACTTCCTGGCAAATTTGAAAATGCACATTGACTGCGTCCATGGTTTGAAAGACGTGCGCTGCAACATCTGCGATAAGTACTTCAACTATAGAGCCTACCGTACCCACAAACGAACCGCCCACACCGATCTGATGCTGATGTGCGAACATTGTCCAAGAATGTTTAAGAATCGAAAATCCTTCGAAGCACACAAAGCTTTCCACGATAGTTCGTTGCTGCGGATGACACAGTGTACCCTGTGCGGCAAACAAATCCGCACCGTCAGCATGTCCAAGCACATGAAAACGATCCACTCGGAAGACGATCCGGTGAATTGCGATCTATGCGGCAAAATGTTCCGCACACCGTTCCACATGAAGCGGCACCAGAAGAATACCTGCGAGGTAACGATGGATTCACGGTCGTTCAAGTGCGAGGTATGCGGCAAAGGTTTCTCCACGAAGTTGACGATGGTCGAGCACATGACGACGCATACACGCACCAACCAGTATCAGTGTGCGTTTTGCTTTAAATCGTTTGGTTACATCTCCAACCTGTACAAACACCGGAAGAAGGCACATCCGCAGGAATGGCAGGAGGTACAGGCACACCCGGAAGAAAACATTCCGTCGGTTATTGTTGTGAGAAATTAG
- Protein Sequence
- MAHSNNCALCFTNDSKWFMEVFSDANSELDMASIISKHLWFELKPAENPQVCNECWTSLHDFHLFYTTLAGIHSADIEGNDTIEQQTEKSELFGAIERDPFRENDNEPEPDREVKPVTGKISARVTNPPITYETEAGPSSKDEKKHFVEVIDYVSNDEDFDDFYQSEDNMLDDDTLNIDYKENALTEESTQIDANDITMVEEEPPKRRSGRPSKIKLEQDVSPTEALKEPRTTVSTATPKRPRGRPPKQTPNAQSTKEANDIGVKEEKSPLQTTSTAAPLPIKRGRGRPPKRRLEASTADYKLRSGIKIEVSEENSPHTIADSTKKKTIRARKPTPERESEQDDISDDEEWQVNKNVTKRFRKDRDERIFKYVDEFSCYYCIDHVTFKRFIEANRHYKLVHQESAFLKCTICEKKCYTPGMFVSHMETHEDPAKNICTICGKVTDCNISLKKHMRVHSRQLEQNLPFPCSSCKRRFESEELRNKHEKLHVPKPLVKRDKGPDLEVLAFYKRIYCDVCEEATPNSTSFENFWDLRVHMEQEHNKNAYLKCPICNKRNLYRQHLITHIDMHNNPEKYRCEVCKEIYQNLDTHMIKAHTPTTAIPADKKYKCDQCGRMFNYLAHLKIHIDCIHGSKDVRCNVCDKYFNLKAYQVHRRTAHTDKMFICEQCPKMFRTRGSLEVHKTTHDSTSVQFKPCKLCNKQIRITNIYKHMVTQHSQDGPANCELCGKTFRTMFHMKRHQKNTCEATINSRKHKCEVCGKGFCLKLTMIEHMTTHTRSNKYQCAFCFKSFGYISNLYKHRKKAHPQEWQDILARPEEGIASVIVLHQDTDPYICIDCWTAVNEFHLYYTRLETIHNEGLDNTSVTAYDASELKNIEFLEEDADELLQLTQASFDETRAEHEINVKGALNSAQKHKTSPKYSKQSDTKGVIELDGYRIVKIEVDGAEDDDGTLYDTDDDQSDPEAPDRSTKPVILNGRTKANVASESSTIAIDILEEPPVKRGRGRPPKRKPEQQQFEGHNAKIKRDLDESGASIDSTGGDIVDEPVKRRRGRPPKNANALHNVSNTTPRMVKKEIKSDSTDEVTPDRYTSSRPERRSTRVRKVKRYSDMEPASDEESEVQDTQYILSEDPDYEAKLELQKQLNMDDFAFYEYQCSLESEQVARDNKIFQYVDEFACYLCSEKVTFKRFADAHLHYRVEHNQPPFLKCPKCDKKCHTPGMFVSHMETHDDPEKNKCEICGKYNDCNISLKKHMRVHQSQLEENLPYPCSLCKRKFATEDLRAKHEKLHVPKPYVPKEKGPDQEVLDFYKCIVCDICEEETPDSTSFDNLSDLRAHMVKEHNKNMYVRCPVCSTRQANRQQVITHIDMHNNPDKYRCELCNEVHQNLHHHMLKAHSPSTAQSSDSAKHKCEQCGRTFNFLANLKMHIDCVHGLKDVRCNICDKYFNYRAYRTHKRTAHTDLMLMCEHCPRMFKNRKSFEAHKAFHDSSLLRMTQCTLCGKQIRTVSMSKHMKTIHSEDDPVNCDLCGKMFRTPFHMKRHQKNTCEVTMDSRSFKCEVCGKGFSTKLTMVEHMTTHTRTNQYQCAFCFKSFGYISNLYKHRKKAHPQEWQEVQAHPEENIPSVIVVRN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -