Basic Information

Insect: Anopheles funestus
Gene Symbol: -
Assembly: None
Location: Contig2:9967478-9978508[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.98 60 4.1 0.0 2 23 4 25 3 25 0.96

2 14 0.0015 0.09 13.0 1.6 1 23 1557 1580 1557 1580 0.97

3 14 0.0095 0.58 10.5 2.5 1 23 1709 1731 1709 1731 0.98

4 14 0.0016 0.096 12.9 4.8 3 23 1735 1755 1733 1755 0.96

5 14 0.00019 0.012 15.8 1.8 1 23 1761 1783 1761 1783 0.98

6 14 3.6e-05 0.0022 18.1 3.5 2 23 1790 1812 1789 1812 0.96

7 14 0.00069 0.042 14.1 0.6 1 23 1822 1844 1822 1844 0.98

8 14 0.00015 0.0089 16.2 2.8 2 23 1850 1872 1849 1872 0.96

9 14 0.0085 0.51 10.6 0.6 3 23 1886 1905 1885 1905 0.97

10 14 7.9e-05 0.0048 17.0 1.0 1 20 1912 1931 1912 1934 0.91

11 14 0.00094 0.057 13.6 0.2 1 23 1942 1964 1942 1964 0.97

12 14 9.1e-05 0.0055 16.8 3.1 1 23 1970 1992 1970 1992 0.98

13 14 0.00049 0.03 14.5 5.8 1 23 1998 2020 1998 2020 0.98

14 14 0.0031 0.19 12.0 3.5 1 23 2026 2048 2026 2049 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.98	60	4.1	0.0	2	23	4	25	3	25	0.96
2	14	0.0015	0.09	13.0	1.6	1	23	1557	1580	1557	1580	0.97
3	14	0.0095	0.58	10.5	2.5	1	23	1709	1731	1709	1731	0.98
4	14	0.0016	0.096	12.9	4.8	3	23	1735	1755	1733	1755	0.96
5	14	0.00019	0.012	15.8	1.8	1	23	1761	1783	1761	1783	0.98
6	14	3.6e-05	0.0022	18.1	3.5	2	23	1790	1812	1789	1812	0.96
7	14	0.00069	0.042	14.1	0.6	1	23	1822	1844	1822	1844	0.98
8	14	0.00015	0.0089	16.2	2.8	2	23	1850	1872	1849	1872	0.96
9	14	0.0085	0.51	10.6	0.6	3	23	1886	1905	1885	1905	0.97
10	14	7.9e-05	0.0048	17.0	1.0	1	20	1912	1931	1912	1934	0.91
11	14	0.00094	0.057	13.6	0.2	1	23	1942	1964	1942	1964	0.97
12	14	9.1e-05	0.0055	16.8	3.1	1	23	1970	1992	1970	1992	0.98
13	14	0.00049	0.03	14.5	5.8	1	23	1998	2020	1998	2020	0.98
14	14	0.0031	0.19	12.0	3.5	1	23	2026	2048	2026	2049	0.95

Sequence Information

Coding Sequence: ATGGCGATCGAATGTCCCGTCTGTACGCTGTTCCTGCGGTCGGGCATGAGCCTGGCCGAGCATTTAGACACCCATCCGAAGGAGAATGTGATAAAGGCGTTGGTTAGCCGGGTGAAGCACGATGTGGTCGGCTACTATCCCGGTACGCTCGAAGAGTTGGGCACCGATGAAATCATTCCGGCGGCGGGCAACACAACCAGCATCGGTACTACTGCGTCCGCGAGCAGCAATGCGCTCACGATACGGACGAACGAACGGACCACCTCGCTGGGCATTTACGATACGCAACCGGCGGTGTATATGGATAATGCGATACTGGCCGCTTCGAGCAGTGCCGTACAGGCGACCGTTAGCCAACCGCCACAGTTTGCCGTGGTAAAAGCGATCGATGCGCACGGTATGCCCAGCTTTCAGCTGAACAATGTAACGCTTATAAAGCGGGAAATGGTACAACCGGTCGCGACAGTATCAGCACTGTCGACAATAACAACCGTCGCTTCTGCACAGCCCGCTACGATCGGTACGATGCAAACGGCTGATCTGTCGGGTATCGGCACTTTGGGTGAAGATTATACCGAGTCGAGTGGAAATGGAAACGGGGAGGCAGGTTCCTCCCGTACCACCGGACCGACTGTTGCGTCTGCCACCTTTTATCCGCGTTACACCAACGAGCTGTACTCTGGACCACCGCCACCGTACAGTCGGGCCATATCATCGACGATTGCAACGAACACGCAGATTACACCGATCCAACACCAAACGGTACAGTTGACCGTACCGAAAAGCAGCGTTGGTGTTGTCGCGCAACAAATTCAGCTGGTTCCCAAGCTGCACACGGAAGCATCAAATTCCGCCTTCAAGCAGTACGCATCAGCGCAAACCGTAACGGAACGTGGTGTCGATGAAGGGGCCGTAACGGCAAACCCACCACCAGTACCAACAACACCGAAACACGCTTACGGTGCTGCGACAGCAACAAACATCGGTACAAGAGTTGTTGCGGCAACATCCAACACCATCACCAGCAGCACTGGCGGTTCAGCTGCGTCAACCGAACAATCGTTAACTGCTATCACATCCAAAGCTAATCTGTTGTCCACACCATCACCGAAAGCGAACGTTGTGAAGGTCATCAGCAACGTAAAGGTGCAGAGTAAGTTGAAGGATATACAGGAAATTATTCTTCAGCTGAATGCCGGCCAGATGTCGATCGTAGGCGACAAAACGACACTAATACCACCCACAACCGAACGACGACCATCGACATTCGCAACGAGCGCTCCCGGTCGATCGTTGCTAGCGATAGCGCCTAAAACGGAATGCACCACGGAAGAACAGAACCAGCAGCAGGCTAATATGTCCGGGAGTGTGGAAATATCTGACGACCAGAATGATATGGAACACATGGCAACCGATTACGACCATGAGGAGGTATATAGTGACGCTTGGCAGGATGAGGATAATTATGCGGACGAAGAAATTCGAGAGCAGTGGGAAGACGAACAAGGGGAAAGCAAGCGTTTCGCTAGTGGCGATGAGCAAGGGGAGCTACATTCGGTACAGCAAGGTTCAGAGTTAAAATCAGCCTCAGTAACAGCTGCGGCCACTAACACTAATACCAACAGTACAGCCATCAGTAACGCAATGGTAACTAGCGTTATTCGGAAAACACCACAACCACTACCATGTTCCCCGTCACCCATACAGCAGCAAATAAAACGGCTGGTGTTCCGAATGACAGGCAACACTACACCAACCACCGTGACGATTTCACCGTCCTCCGGACCATCAACGCCGCCCAAAATCGTACGCGCCTGGCAGGGCATAAAGCTGGAATGTTCACCGGAAGGTACGAGCCCGCCGAACAATGCGACCAACAACAACACCACCACCACCACTGCCGTATCGACACCGGCCGAAGAAGAGATAGGCAAAAGCTTCTCTTGCGCATCGTCTGCGTTAGCCGGTCGTGATTATGTTTCGCGCCAGAAGCAACGTTTTCGGCCACCGAAAAAGTTAGCAATCAAGCCAAAGCGTACACAGCCGCAGGATGGTGAATCGCAACGTGCCGCCGATGGTGGTGAGGTTGCGGTGCACGACCAGGATGAGATGGTGGGAATGAATCCGGCCTGGAGTGGTATGCCTTCCGCTACGATAGAGCTTGCGACCGCGCTCAATACGCTGGCGGAAGTTGTCTGTACGAATGCGGCCCAGCAACAACAGCCACGAACGGAACCGTTCTCTTCCACATCGTTCAACGGCATTACGGCCGTAATACAAAAGACTGATGCTAACAGCGGTATTGTAGCACACACTAGCTCAACGGTCCCTGTCCATGCGTACCGGCCACCGGACGATGAGAAGCTGGAGCATCATCCGCTCGCTTCTAGCACACCGACCAGTTGCTACGTCACGATGGAAAATCACACGTTACACACGCAGCAGTTGCTGATGAAACCGATCAAGCAAGAGTATACCCGGCTGGTAGATAATGCACCGTCAGCTGCACACACTTCAGCGAAACCATCGATCAAATCAAACCAACTGCACGATGCTGCTATCGACGGACACAAACCATCGCATCCAAAAGAAGAGATCGATGTCGGTGCGTACAACATTTCCTACGTAAATGAGGCGGGCGAAACGATTTACCATCCACTGCCAAGGATAAGAAACAGAGCGATCGAATCGCCCAGACGGGACACGATCGCGGAACAGGTCCAGCGTCGTTTGATGGAGCGCGATGGGCGAATTGAGCTTATGGCGGAGGATGTAACCGACTGTGCACCATTGCAAGGAGAGGAGGAAGAGGAAGAGGCGGAAGTGGAGGAAGACGAGGAAGCGGAAGAGGACGAAGAAGAGGATGAGGATGAGCCGGAGGAAATGGAAGAGGAAGATGAGGAGGAGGAGGAAGAACGGTGTAATGTTAAGAAAATGGACGATAATGAAATGATTGAAGCAGATGAGGATGATGAGAAAGAAGTGGACGATGATATGGACCAGGAAGCGAACGTCGTGTACGAGGAGCAATTGGATAGTGATGAGGATGAATATGACAATGTGTTCCAGGAGGATCCAATAGGACATCAGGAGCCGAAGCGTTCCGCGTCACCAATTCCGTCGGACCAGCCAGAACGGGAACAGTTGCTAATGATGCTGAGCCGGGTGAAATCCGACAAATCCGACGCAGTTGATCCGTTGAGCATTACCGACATGAAAAATGAATCGATTGCCGGTATGCAGGAAGGTTCAATGCAGCCGTACAGTAAATCGGATGATGCGAACAATTTGCCCGGCACTCTGGTGATGAAACGTTTCCATTCCGGTATTATCACTACGGACGATGAGAAGGATTTGCTTGAGGCTGGACCATCGTCGCGTAAGATCGAACACGTGGGTGGGACACGGTCGAAGATGCGTGCGGCGAACGTTGGCACAAGGAAAGCGGATAGAGATGAACAGCGAAAGAAGGCGGAAACGTTGAAAGGAAAGTGTGGGAAAGATTTCCACGAGGCGGGACCCTCATCCTCATCGTCGCCACGCTTTGCTGGCGGTTCGATGTACGAACACACCGAGGAAGGTTGTATGGGACATCATAGTTTTAATAATTCCACCACAACCATCGCTAACGCCGATGAGCAAATGTCGCCACAATCGATGATTGGTCTGAAAACGGCTAAAACGGAACCGTACGCTGAAGATGAGATGGATACGTCAACTTCTTCGTTTCTGGATATGAGTACGATACCGAAAAACAGCTTTGACGGTATGACGAATGATACGGCTAGTAACACCAGTAACAGCACCAGCCAGAGTGCTGGTCTCGGTAAGGAACATGGTGAAGGTAGTGGCATTAGCGGTGGTACACGGTCCCTCTTACCGTCCGGCTCATCGATTGCGTCCACCAGCATGGAGCGGGCACCGTCGACGGAAAGCCTAAACATACGCACCGACGAAAAGATGCCGGCGAAAGGTGAAATTTCCGAACAGGAAAGCAACGGCGATATGGACGTTACTTCCTGGAATCATCGGATGTACGCAGTCGGTGAGAATGTACCGATTTATCCAAGCTCATATGATTTATCAACGGCACAGGAGTGTTGGAATCTGAGCAGCCGGAATCAGGGCATGTTTGCCGTAACGGATCATTTTTACCATCAGCAGCAGCACAGCGGTGGCAACAACGCACACGCCACCACGGTCAGCAACCAATACATCAATTCGCGCGTTTCATTCCAATTTTCCTCCACCACACATCAACACCATCAGCAGCATGGAGCGGATCTACCGTTCGGTGGTGGTATTATGACGGGCAAAGTTGAACCGCAGCAGGACGATAACAACGATAGTGACGATGTGGACGAACAAACGGAAGGACGGCGGCTAAAGAATGCTATACCGAAAATGCCATTCGCTGACATGATGGTAGCACGCATCCATGAACCACCCGGTGCGTACGATGAGGTGGTCACACATCACCATCACCACCATCATCATCACCAGCAACAGCAGCAAACGTGCGAAACGAAGTATGACACTTCGGCCGGGACACCGTCGTACTTTGGTGTGGCTGCTGCCGGTTGCTCCACTTTACCGTTGATGTCTGGCGAGGTGGAACCGGTACTGTCGAGCCGTCCAAAACCGTCCGGTAGTGGTGTGCCGCGTACCTTCCGCTGTACGCTTTGTCCGAAAGTGTTCGATACGATTAAGCAGCGCCGGCAGCATCAACAACGGGAACATGCGACGGAACTGTTGGCACTATCGTCCCACACAACGCAAGAGCAGGCCAATGAACGGAATGGTGCAGGAATGCAGCAACAGCAGCAACAGCAGCAGCAGCAGGTGTACAAGAAGCAACCGATACCGGTCGTCATGAACTACGATTGGATGAAGCAGGAAATTCAGCGGAAAAGTGAAGCAACGCTTAAAAGTAGTCGCATGCTGTTGCCGGACGGTAGCAGCAGTTCCGCCGTACCCGGTACGAGTGGTGAAGAGTTACTACAGCAGCAGCTTGTAGTGGCACAGGTTCAGGTACAGCCGGACGGCTCTACGACGGACGGTGCGGCATTGATGCGTGACGGTATGTTACCATCCGCCTGTACCGTAGCGGCACGCAATCGAACGTACGTATGCGGGACCTGCCATCAAAAGTTCGATCGATTTAACCTGTTCAACGAACATTTGAACGTCCATCCGGTGCACTGCGTTACGTGCGGGCGACACTTTAAGCAATGGCGTAACTTCTCGCTTCACATCAAGCGCCATCTTGGCATCAAGGAGCACCAGTGCCGAAACTGTGGCAAACAGTTCGTCATCAAGCAGAAGCTGATCGAGCATATGCGGGTACATACTGGACATGCACCGATCAAGTGTAAGCTTTGCAATCGTACGTTTAAGCGTTTCTCGAATCTTGCCCAACACCGGAAGCGTTACCATCTCAATCGGACGGTAACGAAGGAGGACTATGTGTGTCAGCTGTGTGGGGAAGTTTTTCACACCCAGGCGAAGATGGAATGGCACAAAGAGACACACGAAAAGAAGCCAAAATCATGCCCCTACTGTCGGGAAAAGTTTATCCACCGGAACAGTCTGACGCGTCACATCCGGTTGTCGCACACGGACAAGTATGCGAAGCTGGAGAACAAAACCGAACCGTGCAGCATCTGTCAGCAGCCGTACACGAAGACAAGCATGCGCCGGCACATGGAAACGCACACCAAGGAACGGATGGCGTTTGCGTGCGGCATATGCAACAAGCGGTTCACGACGAACTGGAACCTAAAGCAGCACAAATGGACACACGCAAACCCGACGATGAAACCGTTCCAGTGCACCTACTGTCCGAGTGCGTTCGTGCGCGAATCGGACTTTGTGACGCACGTTAATGCGCACCGTTCGATACGGCCGTACACGTGTAACCATTGCGGTAGTCAATTCATACGCAAGTACAACTGGATACGTCATACGCGCGAGCACGAGATCGATAAGGGCCATCGGTGCGATGTGTGCGGACGTCAGTTTCACCGGAAGTACTACCTTACCGAGCACAAGCGCATACACACGGGGGAGCGGCCATTCGCGTGCAACATTTGTGGTAAAACGTCCGCCACCAAGACGAACCATAACAAGCATGTGCGGATACATCATGCGCGTGATCCACTCACCGCAGAAGGGAATAAATTGTAG
Protein Sequence: MAIECPVCTLFLRSGMSLAEHLDTHPKENVIKALVSRVKHDVVGYYPGTLEELGTDEIIPAAGNTTSIGTTASASSNALTIRTNERTTSLGIYDTQPAVYMDNAILAASSSAVQATVSQPPQFAVVKAIDAHGMPSFQLNNVTLIKREMVQPVATVSALSTITTVASAQPATIGTMQTADLSGIGTLGEDYTESSGNGNGEAGSSRTTGPTVASATFYPRYTNELYSGPPPPYSRAISSTIATNTQITPIQHQTVQLTVPKSSVGVVAQQIQLVPKLHTEASNSAFKQYASAQTVTERGVDEGAVTANPPPVPTTPKHAYGAATATNIGTRVVAATSNTITSSTGGSAASTEQSLTAITSKANLLSTPSPKANVVKVISNVKVQSKLKDIQEIILQLNAGQMSIVGDKTTLIPPTTERRPSTFATSAPGRSLLAIAPKTECTTEEQNQQQANMSGSVEISDDQNDMEHMATDYDHEEVYSDAWQDEDNYADEEIREQWEDEQGESKRFASGDEQGELHSVQQGSELKSASVTAAATNTNTNSTAISNAMVTSVIRKTPQPLPCSPSPIQQQIKRLVFRMTGNTTPTTVTISPSSGPSTPPKIVRAWQGIKLECSPEGTSPPNNATNNNTTTTTAVSTPAEEEIGKSFSCASSALAGRDYVSRQKQRFRPPKKLAIKPKRTQPQDGESQRAADGGEVAVHDQDEMVGMNPAWSGMPSATIELATALNTLAEVVCTNAAQQQQPRTEPFSSTSFNGITAVIQKTDANSGIVAHTSSTVPVHAYRPPDDEKLEHHPLASSTPTSCYVTMENHTLHTQQLLMKPIKQEYTRLVDNAPSAAHTSAKPSIKSNQLHDAAIDGHKPSHPKEEIDVGAYNISYVNEAGETIYHPLPRIRNRAIESPRRDTIAEQVQRRLMERDGRIELMAEDVTDCAPLQGEEEEEEAEVEEDEEAEEDEEEDEDEPEEMEEEDEEEEEERCNVKKMDDNEMIEADEDDEKEVDDDMDQEANVVYEEQLDSDEDEYDNVFQEDPIGHQEPKRSASPIPSDQPEREQLLMMLSRVKSDKSDAVDPLSITDMKNESIAGMQEGSMQPYSKSDDANNLPGTLVMKRFHSGIITTDDEKDLLEAGPSSRKIEHVGGTRSKMRAANVGTRKADRDEQRKKAETLKGKCGKDFHEAGPSSSSSPRFAGGSMYEHTEEGCMGHHSFNNSTTTIANADEQMSPQSMIGLKTAKTEPYAEDEMDTSTSSFLDMSTIPKNSFDGMTNDTASNTSNSTSQSAGLGKEHGEGSGISGGTRSLLPSGSSIASTSMERAPSTESLNIRTDEKMPAKGEISEQESNGDMDVTSWNHRMYAVGENVPIYPSSYDLSTAQECWNLSSRNQGMFAVTDHFYHQQQHSGGNNAHATTVSNQYINSRVSFQFSSTTHQHHQQHGADLPFGGGIMTGKVEPQQDDNNDSDDVDEQTEGRRLKNAIPKMPFADMMVARIHEPPGAYDEVVTHHHHHHHHHQQQQQTCETKYDTSAGTPSYFGVAAAGCSTLPLMSGEVEPVLSSRPKPSGSGVPRTFRCTLCPKVFDTIKQRRQHQQREHATELLALSSHTTQEQANERNGAGMQQQQQQQQQQVYKKQPIPVVMNYDWMKQEIQRKSEATLKSSRMLLPDGSSSSAVPGTSGEELLQQQLVVAQVQVQPDGSTTDGAALMRDGMLPSACTVAARNRTYVCGTCHQKFDRFNLFNEHLNVHPVHCVTCGRHFKQWRNFSLHIKRHLGIKEHQCRNCGKQFVIKQKLIEHMRVHTGHAPIKCKLCNRTFKRFSNLAQHRKRYHLNRTVTKEDYVCQLCGEVFHTQAKMEWHKETHEKKPKSCPYCREKFIHRNSLTRHIRLSHTDKYAKLENKTEPCSICQQPYTKTSMRRHMETHTKERMAFACGICNKRFTTNWNLKQHKWTHANPTMKPFQCTYCPSAFVRESDFVTHVNAHRSIRPYTCNHCGSQFIRKYNWIRHTREHEIDKGHRCDVCGRQFHRKYYLTEHKRIHTGERPFACNICGKTSATKTNHNKHVRIHHARDPLTAEGNKL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -