Afun012629.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles funestus
Gene Symbol
-
Assembly
None
Location
Contig0:92041187-92045379[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 2.1e-05 0.0013 18.8 0.6 1 23 133 155 133 155 0.99
2 11 9.2e-05 0.0056 16.8 2.8 1 23 161 184 161 184 0.96
3 11 2.1e-06 0.00012 22.0 0.4 1 23 190 212 190 212 0.99
4 11 2e-06 0.00012 22.1 0.2 1 23 218 240 218 240 0.98
5 11 0.008 0.48 10.7 3.0 1 23 246 268 246 268 0.98
6 11 8.9e-06 0.00054 20.0 3.1 1 20 274 293 274 297 0.95
7 11 0.028 1.7 9.0 5.5 1 23 303 323 303 323 0.97
8 11 1.1e-05 0.00066 19.7 0.1 3 23 331 351 330 351 0.98
9 11 1.5e-05 0.00092 19.3 1.1 1 23 357 379 357 379 0.99
10 11 3.3e-05 0.002 18.2 0.7 1 23 385 408 385 408 0.97
11 11 0.015 0.92 9.8 1.2 1 20 414 433 414 434 0.92

Sequence Information

Coding Sequence
ATGATGAAGAAATCTACGCGTCAAACCCGAATGTCTCGGTACGTGGGTAAACATTCGCCAAAGATCGCGACTCCAGATGAGGGCAACAATAATAATAACAACGGCAAAGGAAGGATCGAAACCGCTGCGAAAATAGTAACAAGTGGCGATGAAGAGATGGCACTGAGTGAACTTCCTTTGTACATCGTGGAAAAACCGATCAATTACGACGAAACGTCGGCAGACTTTGAGGACGAGGATGATAAGTCGGTTGTGAAGAAGCTGGTCGACGATGTGACCGGCGGCGACGAAGGGGATGGTGGAGAATCGGGCAGTGGAACCGATGGCACGCTATCTTCCGCCGGTGGTTCATCGTCGACGTCCAAGCGTGGCCGCAAACGCCAGGAACGGAAGCTGTATCAGTGCGAAGTTTGCCAGAAGGAGTTTATGGGTACGAACGATTTGCGCAAACATTTGCGAATACATAATGACGAACGGCCGTACCCATGTCCGCACTGTAAGAACCGCTTCCGGCAGGCCGGTTGCCTGAAGAACCACATCGCTTCACAGCACGGCACGGACGAACAGTATACGTGCGATCTTTGCGGTAAATCGTTCCCGATCAAGGAGCGGTTACGGCTGCATATGCGCATCCACACCGGTGAAAAACCGTACAGCTGCTCGATTTGCCCGAAAACCTTCGCACGTGGTGGACAGCTAACTCAACATCTCGCCACACACAACGGTGTGAAGAAGCATAAATGTGACCAATGCACAGCAGCGTTCTCCTGTGCGGCTAACCTGAAGATGCACCTTAAGAGCCACATGGACATCCGCGACTACACGTGCCATATCTGCGGGCGCGGATTTTATCGGCCGGATGCGCTGAAAAAGCATCTGCTCTGCTACCATGCTAATCTGAAAGCGTTTCACTGCAACATATGCAACAAAATGTTCAAGGGACATTTACCGCAGCACATGCGTACGCATCTGAAGGTCCGTCCGCACGGTTGTGCCGTGTGTGGTTCGGTTTTCTCACAGCGATCACAACTGATCGTTCACCAGCGCATTCACAGTGGCGAACGTCCCTATCGATGTCAGGTTTGCTGGCAGGCGTTCGCTCACTCAAGCGTACTAAAGTTGCACATTCGCAAACACACGGGCGAAAAACCGTTCGAGTGTCCGCTGTGTGTGTCGAGCTTCTCGCAGCTACCGCATTTGAAGAAGCATATGCTCTCTATTCACCAGCAGGACAAATCGTACCTGTGTCAAAAGTGTAAGGAATTTTTCAAAACCAAGATGGACTACCAGCTGCACGTCACAGCGTGCTACAAAGATCCGGCCGCATTGAAGAATCTCGACAATATGATGGACCCCATGTATCGACCGACGGAGACAAACGGTATTGATCCACCGATGACCATTTCGCGCATGCGGTTTCTGGTTGCCATTTTGCTGAAGAAAATTTCCAGCGAGGATCGGCTGAAGGAGCTGGGCTTCGATAAGCGACTGATTGATAACGTTCTAATCGGTTCATTAAAATGTGCTGGCCGCAAGGTATGTGACGACAAGTCATATGATCCGCTGGAACGGTTGAAGTTAAACGTACAAGAGCTGCTGGAATGGACTGTACCGCCAAACTATATGGAAGAATTCCGTGGCGCGAATCGTAGCACCGAGGAACTGCTTGAGGAACTCACCAACTAA
Protein Sequence
MMKKSTRQTRMSRYVGKHSPKIATPDEGNNNNNNGKGRIETAAKIVTSGDEEMALSELPLYIVEKPINYDETSADFEDEDDKSVVKKLVDDVTGGDEGDGGESGSGTDGTLSSAGGSSSTSKRGRKRQERKLYQCEVCQKEFMGTNDLRKHLRIHNDERPYPCPHCKNRFRQAGCLKNHIASQHGTDEQYTCDLCGKSFPIKERLRLHMRIHTGEKPYSCSICPKTFARGGQLTQHLATHNGVKKHKCDQCTAAFSCAANLKMHLKSHMDIRDYTCHICGRGFYRPDALKKHLLCYHANLKAFHCNICNKMFKGHLPQHMRTHLKVRPHGCAVCGSVFSQRSQLIVHQRIHSGERPYRCQVCWQAFAHSSVLKLHIRKHTGEKPFECPLCVSSFSQLPHLKKHMLSIHQQDKSYLCQKCKEFFKTKMDYQLHVTACYKDPAALKNLDNMMDPMYRPTETNGIDPPMTISRMRFLVAILLKKISSEDRLKELGFDKRLIDNVLIGSLKCAGRKVCDDKSYDPLERLKLNVQELLEWTVPPNYMEEFRGANRSTEELLEELTN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00100454;
90% Identity
iTF_00105288;
80% Identity
-