Afun002992.1
Basic Information
- Insect
- Anopheles funestus
- Gene Symbol
- -
- Assembly
- None
- Location
- Contig1:91173642-91175952[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 4.9e-05 0.0029 17.7 1.0 2 23 29 50 28 50 0.96 2 18 2.4 1.4e+02 2.9 10.7 1 23 56 78 56 78 0.97 3 18 0.0014 0.083 13.1 4.5 1 23 84 106 84 106 0.94 4 18 0.0023 0.14 12.4 0.3 2 23 112 134 112 134 0.95 5 18 6.8e-05 0.0041 17.2 1.3 2 23 141 162 141 162 0.97 6 18 0.0087 0.53 10.6 0.5 2 23 166 188 166 188 0.95 7 18 8.3e-05 0.005 17.0 1.4 1 20 195 214 195 216 0.94 8 18 0.018 1.1 9.6 6.1 1 23 221 244 221 244 0.98 9 18 3 1.8e+02 2.6 2.3 1 20 387 406 387 408 0.91 10 18 0.14 8.4 6.8 0.1 2 23 422 443 421 444 0.91 11 18 0.15 8.8 6.7 6.1 1 23 449 472 449 472 0.98 12 18 6.1e-06 0.00037 20.5 1.8 2 23 478 499 477 499 0.96 13 18 0.014 0.83 10.0 0.6 1 23 505 527 505 527 0.95 14 18 2.5e-05 0.0015 18.6 1.5 1 23 533 555 533 555 0.97 15 18 1.1e-05 0.00066 19.7 1.1 1 23 561 583 561 583 0.98 16 18 0.0031 0.19 12.0 0.0 3 23 591 612 589 612 0.95 17 18 1.6e-06 9.6e-05 22.4 2.0 1 23 625 647 625 647 0.97 18 18 0.00012 0.0072 16.5 2.0 1 23 653 676 653 676 0.93
Sequence Information
- Coding Sequence
- ATGCAGCCCGCCGAGAAAACTAAGCAAAAGCTACTTCTTGAACGTGGTCAACCACTGGCCACGATTGAGAACAAAAGTGCCATTACCTGTGCTTTTTGCGATAAAACCTTCAAATTTCAAGCGACACTTCGACAGCACGAAAAAGTTCACTACGGTATTAAGCAGCACGAATGTGAGACATGCCATCGCCGATTTTTGCACAAAAGCACCCTAAAGTGTCACCTTCGAGTGCACACGGGTGAAAAGCCGTACAAGTGCCCGCACTGTCCTAAAACATTCCGTGGCCAAACAGCACTAAACTGCCATGTCTTTCGGCACACGAACGAGGGCGCTAAATGCCCCCTATGTGAGAAGGTATTTGCCACGAGTTCGATTGTGAAACAACATCTGAAACAGGTGCATACGAATGAACGATCGAACGTATGCAATCTATGTGGTGCGACTTACAAACATCTCAAGAGTTTAAGAATACATATACGCAACCACCAGAAGCGGGTGTGTCCAGAGTGTGATGTTGAATTTAACAGTGTGTACGCTATGTTAAAGCACCGAAAGCACTCACATATCAAAGAAAATCTTCCATTCAAATGCGAGCACTGTGATCGAGCATTTGAGCATCGTTCCAAGCTTGCTTCGCACGAAAACCTGAGAGGGCGACCGTTTCAGTGTGAACTATGTTGCCATAGCTTCAACAAACAGGTCTACTTGACCAATCACCAGCGTCGAATCCATTGGAGGGAAATGGGTCTGGAGCGGTTAAGAGTGGCCGAACCTCAGAACGGGTGGAACCGAAAAGGCATCCCAAAACCAAAACGCGCAAAGACATCACCGAAAAGTGCTGAGACGGAAGATCTTCACAGCGATTATGGTTTAGTTGAGGACGAAAATGAAAAACAAAACGATCCGGCAATCAAGGAAGAAGCGGTTGCAGTAGTTAAGGAAGAATTGGATCAGTCTGTACAGGAAAGGACCGATGGATGTCATAAAAATGAAATTCAACCAGATCAAGCATATTTAGATGTAATGATCAAACAAGAAGATTTTGCGAATGAATCAGTACATAAAAATGAAGATAAATCGAACAACATGGCTGATGCGAACAATTCAGCTGACCAACCTATTAAAGTTTTAAAAGCTAGATACAATACATATGATGATTTCTGTTGTTCGTTGTGTGGAATTCTTTGCGATGGAGCAGCTGGTTTGCGGCGTCATGAATGTAAACCTGTCCCAAAGAAACAACTTAGTTCAAAGAAACCGTTAATATGTGGAGTATGTGGAAATGTGTATGCATCTCTCGCAACCCTTTACGTTCATAGTGTCAAACACCACCGCAGTGCCCGTTTTCAGTGTGATCAGTGCTGCCGATCCTTTGGCTTTCGTTGCTTCCTTGAGAATCATATACGAACGGAACATGAGCATCAGCGTATGCCATGTAAGTTGTGCGATAAAACATTTAAATACGCTCAAGATTTAAAAGTGCACATGCAACATCACGACGATCCCAGACCGTTCAAGTGCGATCAATGTGCTTCTGTATTTCGGTTTCCTGGTGCACTGAGGTCGCATAAATTTTTGCACCAAATTAAGCTACCGTTCATGTGTGATACATGCGGGAAGCAGTTTCGTTTTGCAAATAGTCTACGTGTTCACAAACGACTGCATACCGGTGTAAAGCAATTTAAATGTGATATTTGTAAAAGAGAATTCTCGACCAAAGCTCCCCTGTTGCGACACAAGAAAATACACGATAGCGGCAGAGAGATGGCATGTGTGGTTTGCGGCATGGTGTATTATAAAAAGGTCGATCTTGAAATACATCAAAGCAAAGAACATCCCGATCATGCGTCCGTGGGCAAAGTGAAACCAATCTATAGCTGTGAGCGTTGTGGTAAAGAATTCACCAAGAAAAGCAATCTGAAAGCCCATTCGTACACACACGAGGAAGTGTATCGATTTTCCTGTAAGTTGTGCAATCAATCATTCAAACAACATGCAGGATTGCGAAACCACATAGTCAATAATCACAAACCAGCAAAAGTGCCTACATCGGCGGAACTGATCGATCGAATCGAAAATTTGCAGCCAAATTGA
- Protein Sequence
- MQPAEKTKQKLLLERGQPLATIENKSAITCAFCDKTFKFQATLRQHEKVHYGIKQHECETCHRRFLHKSTLKCHLRVHTGEKPYKCPHCPKTFRGQTALNCHVFRHTNEGAKCPLCEKVFATSSIVKQHLKQVHTNERSNVCNLCGATYKHLKSLRIHIRNHQKRVCPECDVEFNSVYAMLKHRKHSHIKENLPFKCEHCDRAFEHRSKLASHENLRGRPFQCELCCHSFNKQVYLTNHQRRIHWREMGLERLRVAEPQNGWNRKGIPKPKRAKTSPKSAETEDLHSDYGLVEDENEKQNDPAIKEEAVAVVKEELDQSVQERTDGCHKNEIQPDQAYLDVMIKQEDFANESVHKNEDKSNNMADANNSADQPIKVLKARYNTYDDFCCSLCGILCDGAAGLRRHECKPVPKKQLSSKKPLICGVCGNVYASLATLYVHSVKHHRSARFQCDQCCRSFGFRCFLENHIRTEHEHQRMPCKLCDKTFKYAQDLKVHMQHHDDPRPFKCDQCASVFRFPGALRSHKFLHQIKLPFMCDTCGKQFRFANSLRVHKRLHTGVKQFKCDICKREFSTKAPLLRHKKIHDSGREMACVVCGMVYYKKVDLEIHQSKEHPDHASVGKVKPIYSCERCGKEFTKKSNLKAHSYTHEEVYRFSCKLCNQSFKQHAGLRNHIVNNHKPAKVPTSAELIDRIENLQPN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -