Basic Information

Insect: Anopheles funestus
Gene Symbol: -
Assembly: None
Location: Contig0:2329356-2335974[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 0.74 45 4.5 0.0 10 23 218 232 199 232 0.81

2 26 0.0025 0.15 12.3 0.5 2 23 241 262 240 262 0.96

3 26 0.00011 0.0067 16.6 2.0 1 23 293 316 293 316 0.97

4 26 0.2 12 6.3 0.4 2 23 322 343 321 343 0.79

5 26 1.3e-05 0.00077 19.5 2.0 1 23 347 369 347 369 0.96

6 26 0.00023 0.014 15.5 0.6 2 23 380 402 380 402 0.97

7 26 7.4e-05 0.0045 17.1 0.3 2 20 409 427 408 429 0.92

8 26 6.4e-06 0.00039 20.5 3.4 1 23 436 458 436 458 0.98

9 26 2.7e-05 0.0016 18.5 2.8 1 23 464 487 464 487 0.97

10 26 0.053 3.2 8.1 0.2 2 19 777 794 776 796 0.94

11 26 0.00017 0.01 16.0 3.5 1 23 829 852 829 852 0.97

12 26 0.053 3.2 8.1 0.4 3 23 859 879 857 879 0.94

13 26 5.7e-05 0.0035 17.5 2.6 1 23 883 905 883 905 0.97

14 26 0.024 1.4 9.2 0.1 2 23 916 938 915 938 0.95

15 26 0.0042 0.26 11.6 2.2 2 20 945 963 944 965 0.94

16 26 2.7e-07 1.7e-05 24.8 1.4 1 23 974 996 974 996 0.98

17 26 0.0049 0.3 11.4 4.3 1 23 1002 1025 1002 1025 0.97

18 26 7 4.3e+02 1.4 0.0 9 23 1284 1299 1267 1299 0.78

19 26 0.002 0.12 12.6 0.1 2 23 1307 1328 1306 1328 0.97

20 26 0.049 3 8.2 0.7 1 23 1334 1354 1334 1354 0.89

21 26 0.003 0.18 12.1 1.1 1 23 1359 1382 1359 1382 0.97

22 26 0.011 0.69 10.2 0.8 2 23 1388 1409 1387 1409 0.94

23 26 0.0016 0.097 12.9 5.4 1 23 1413 1435 1413 1435 0.97

24 26 0.62 38 4.8 0.2 2 23 1446 1468 1445 1468 0.94

25 26 6.9e-05 0.0042 17.2 0.6 3 20 1476 1493 1475 1495 0.94

26 26 6.8e-05 0.0041 17.2 1.0 1 21 1504 1524 1504 1525 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	0.74	45	4.5	0.0	10	23	218	232	199	232	0.81
2	26	0.0025	0.15	12.3	0.5	2	23	241	262	240	262	0.96
3	26	0.00011	0.0067	16.6	2.0	1	23	293	316	293	316	0.97
4	26	0.2	12	6.3	0.4	2	23	322	343	321	343	0.79
5	26	1.3e-05	0.00077	19.5	2.0	1	23	347	369	347	369	0.96
6	26	0.00023	0.014	15.5	0.6	2	23	380	402	380	402	0.97
7	26	7.4e-05	0.0045	17.1	0.3	2	20	409	427	408	429	0.92
8	26	6.4e-06	0.00039	20.5	3.4	1	23	436	458	436	458	0.98
9	26	2.7e-05	0.0016	18.5	2.8	1	23	464	487	464	487	0.97
10	26	0.053	3.2	8.1	0.2	2	19	777	794	776	796	0.94
11	26	0.00017	0.01	16.0	3.5	1	23	829	852	829	852	0.97
12	26	0.053	3.2	8.1	0.4	3	23	859	879	857	879	0.94
13	26	5.7e-05	0.0035	17.5	2.6	1	23	883	905	883	905	0.97
14	26	0.024	1.4	9.2	0.1	2	23	916	938	915	938	0.95
15	26	0.0042	0.26	11.6	2.2	2	20	945	963	944	965	0.94
16	26	2.7e-07	1.7e-05	24.8	1.4	1	23	974	996	974	996	0.98
17	26	0.0049	0.3	11.4	4.3	1	23	1002	1025	1002	1025	0.97
18	26	7	4.3e+02	1.4	0.0	9	23	1284	1299	1267	1299	0.78
19	26	0.002	0.12	12.6	0.1	2	23	1307	1328	1306	1328	0.97
20	26	0.049	3	8.2	0.7	1	23	1334	1354	1334	1354	0.89
21	26	0.003	0.18	12.1	1.1	1	23	1359	1382	1359	1382	0.97
22	26	0.011	0.69	10.2	0.8	2	23	1388	1409	1387	1409	0.94
23	26	0.0016	0.097	12.9	5.4	1	23	1413	1435	1413	1435	0.97
24	26	0.62	38	4.8	0.2	2	23	1446	1468	1445	1468	0.94
25	26	6.9e-05	0.0042	17.2	0.6	3	20	1476	1493	1475	1495	0.94
26	26	6.8e-05	0.0041	17.2	1.0	1	21	1504	1524	1504	1525	0.94

Sequence Information

Coding Sequence: ATGGCGTTAGCGAAAGAGGAAAAGTATCCCATTGCCAGAGGGCAAAGCGCCCCTTTAGAGCAGCAATGTGATGTATGTCTTCGGAAGGAAAGTGCTTGTTTCGGCAAATCGGATCCCATATTCGAAGGAAAAAATGTCTTAGCCATCGTCGTACAGCATCTGGACTTAAAAATCACACTGACGCGCGTTTGTCAGCATTGCTGGAGCAAATTGGAAGCGTTTGATGAGTTTTATAGAATGGTTAACGAGCAGCATCACTTCCACAAGCCTCTTAAAATCGACCCATCGGATGATGTGATCGGGATGGAGTTTGTAGAAATTAAGCATGAACCTCTGGTTGAGGAAGATAAAGATTTGATGGTAAAGGAAGAAAAGGAACCACTTCCGAACACGGAATGTGACAAGCTATTGCCTGAGCACTCCATGTCAGTAGATAACGACGAAGAGAATCTAAAGAATGAGAACACTAATTACGCTTCATCCGATGAAAGCGAAGATTCCTACACACCACCAAATCCGACTCGAAGCGCCGGAAAACCAACCGTCAAAAAGGAACCCAAGGTGGACACTGAGATACTGGATTTCTATAAACGATTGGTGTGCGAGGTGTGCGACGCAGAACGGATGCTGGCCGGAGAACCTTCGATCGAGTATGGCAATTTACGTGAGCTAAATAAACATATGCGAAAGATGCACGACCATGTGATAGCAACCAGCATCAAGTGTCCTATGTGTGATAAGAAGCTGCGCTACCGAGCAAAGTTGCTGGAACATCGGGACATGCATTTGAATCCGGAACGGTTTCGGTGTGTGGTGTGCCAGGAGGTCCATCAAAACATGGCCGAACACATGAAGAACAAACATCAGGAACGAACATACTGCTGTGAGGAGTGTGGCAAGCGGTTCCCATTTAAGGCTCGACTTACGGCACATGTCAAGAAAATGCACACAACCAAGGATGTCGTCTGTGACCAGTGCCAGAAAAGCTTCAGCAAATACACCATCGATGACCACAAACGAGCGGTACATGAGTCAAAGTTTATTTGCGAACACTGTCCACGCACGTTCAAGTCGCGCTTCTCACTCGAACAACATATGGAGGAGCACGTGGAAGGGCTGCGCAAATCGATGGCCGCCACTTGCGACAAGTGTGGCGTTGTGTTGCGCGACAAATACACGCTGCAATCGCACATCAAGCGAATGCACACGGAACATCCGCCGGTTAGTTGTGTATCGTGCGGGAAGGTATTCAAATCAAAGCATAATCTGAACGCACATCTGGCAAACGTATGCACCGAGCGGAGCTTCCCGTGTCATATCTGTGGGAAGCAGTTTAAGAAAAAGATTAAGCTAAAGGAACATATGACGACACACACGAAGAGTGCGCTGTATCAGTGCCCGTACTGTCCGAAAACGTTCAGCTTCGAAACGCAACTGTACACGCACCGGAAGCAGAAGCACTACGAGCAGTGGCTGGAGATGCAACGGAAACGCAAAGAGGGCGTTCGGTTTAAGGTCAATCGTGTCTCCGACATGCCTGCCATAGAGTTGGTACTGGTGCTGGTGGAAAACATCACGTTAAATTCCTGTGCAATAACCATGGCAACCAAATGCGAAGTATGTTTCTCGACGACGGAATGCAATATGAAGGAAATATTCTCGGATGAAAATAAACATATTGTAGAAATAATAGCGAAACATCTGTGGTTTGAGGTAGTACAAACAGCGGTAGATACTTGGGTGTGTATCAAATGCTGGGACGCTTTGCAAGAATTCCACAAATTTTACTGTGAAGTTGAAACATCCCGACAACAACAAGCAGCTCGTGCGCTAATTGACAAGGACGAGGAAGATGTTTCCGGTAGCTTGGAACCAAAATACAGCACAGAATTTTTCGAGGTGAAGGTAGAACCGGGTGAGCTGTTGGATAACACTGTAGAGGAAGATGTAAACTGTGCCGATGAAAAGGCAGTGCATTGTGCTTTCGTAAAATGCGAAGAATCAATGGAAATCGATCCTACTGCTCCCACGTCGGACGAGGAAGCTCTTCAGGACAATAAGTCGGATTCATCTTCGACAGATGGTATGAAAAATAGGCTGAAGAAAAAATCTAAAAGGCTCCATACTGTAGAAGAGGCGGCAAAGCAAGGCAAATCGATCGCTCAGAAGGAGGAAGATGAAAGTTTGATAAACTTCTACAAGAGGATAGTCTGTGAAAAATGTGATAATCAGCGCATGATGGTTGGTGAGCCTCAGATCGATTTCGGTACGTGGCGCGCTCTGTTGCGGCACACGAAGGAAATCCATAAGCATGATAAAGTATACGTGAAATGTCCGCTGTGCGATTTGAAGTTGCGAACGAAGCAAACTCTCATACAGCACAAGGATTGCCATGAAAATCCGGAAAAGTATCGTTGCTCGCTGTGTAACGAGATTCACCAGAACATGAAGGAGCATCTGCAGAATAAGCACCAAGAAAGGCAGTTCTGTTGCGAAGTGTGCGGGAAAAAGTTTCCGTTCAAGAATAGGCTAACAGTACACATGAAGAAGATGCACGTAGAGAAGGACATAATTTGCGACCAGTGTCAAAAACCCTTCACAAAATACACGATCGAAGATCACAAACGATCCGTTCATTCTGCGCGATTTGTTTGCGAACATTGTCCAAAAACGTTCAACAGTCGCTTCCGTTTACTAAAGCATATGGAGGAGCACGATGAAAGCCTTCGGAACTCCACCTCAGTGCCGTGTACAATATGTGGGCAGGTGATGCGGGACAAGTACATCCTGACCAGGCACATAAAGCTAATGCACAGCGTACAACCGTCGGTGAGCTGCACTACCTGTGGGAAAACGTTCAAATGCAAACGCAATCTTTCCGTGCACATGACAAACGTGTGCATGGAACCAACCCGACTGTTTCCCTGTACAATCTGCGGCAAGGAGTTCCGGCGGAAGAATAAACTAAAAGAGCACATGTCTACGCACACTGGTAAGCCGTTGTACAAGTGCTCGTTCTGCCCAGAGACATTTCGTCAAGATACGCACCTTTACTATCATCGGAAGAATGTACACTACGATCAGTGGCTGAAGATGCAGCAGCAGCAAACCACATCCTACCGTAATAGTAAATTATTGTTCCAACTACAACCAATTAGCACAATGGAAGCCACCATCAGACAATGCAGGACGTGTCTCTCTATCAGCGAGTGCGATTATTTGAGCATATTTGCAGAGGAGAACAGGACGAAGAAAATTGACACAGTTATCGCAGCACATCTTTGGTTTGAGGTAGTTGCCACGAGTGAAAGTCAATGGATATGTCAGAGTTGTTGGTGTAAACTGGAAGAGTTTCACGAATTCTACATCAGCATAAAAGAGACGCATGAACAACGAACTACCCCAGGCGATAGTGATAGTGTCACCGCCAAAGCGACTTCAGATTCACCACCAATTTGTAATGGTCCGACGTACAGTACGGAGTTCCTGGAGATAAAAGGAGAACCGTTCGATATCGAGGAGTTCGATGAGGATGGATACAGTTTAGGGGGAAGCAGTCCATGTGACAAAAGGTTATCCTGTGATGATATAAAGAGTGAGGAATCGGACGAGAGTGAAAGTGACTCCGCACAGCCACAGGATGAAGGGACGAAAAAAAGTGAAAAGTTCACTCGATCGCGTGGATCTAGAGCTTCGAGACAAGCGACCGGTGAACGGCTTGCAAAACGAAAGGCTGGCGGACGCTTTCCTGCCGATCCAGAGGAGGATAAGAATATACTACAGTTCTACAAACGCATTGTGTGCGAGGTGTGTGACAACAAGCGGATGATGGTAGGAGAACCACTGATTGAGTACGCGACCTGGGGCGAACTGTTGCGGCACACAAAGGAGCTGCACGGACATTACAAGATCTTCGTGCAGTGTCCCGTGTGTGAGATGAAGCTGCGCACGAAGGTGACGCTGGTGCAGCACATGGATATGCACCAGAATCCGGACAAGTATCGGTGTGAAGTGTGCGGCGAGGTGTTCCAGAACATGAAAGAACACATGCAGAATAAGCACGAAGAGCGACAGTTTAGCTGCGATCTGTGCGGAAGCAAATTCCCCTTCAAAAAGCGGCTTGTGGTGCACATGAAAAAGATGCACGCGGAAAAGAACGTCACGTGTGATCAATGTCAGAAATCTTTCACGAGATACACAATCGAAGACCATCGACGGTCGGTGCATATGGCTCGGTTTGTGTGCGAACACTGTCCGAAGACGTTCAAGATTCGGTTTCGGTTGCACAAGCACATGCAGGAACACGACAAAAGTTTGCGCATCTCCACGTCCGTGCCTTGTCCGACCTGCGGCCAGGTGATGGGCGATAAGTACATTCTCCGACAGCATATCAAGCACATGCACAACGAGCAGCAGGCTGTCGACTGTGAGACATGCGGGAAGACGTTCAAGAACTATCGCAACCTGAAGATACACCTGACGAACGTGTGTATGAAACCGATCCAGCTGCATCCGTGTGCGATCTGCGGCAAACAGTTCCGGCACAAGAACAAGCTGAAAGATCATATGGCGTCCTGCACGCCAAATTGA
Protein Sequence: MALAKEEKYPIARGQSAPLEQQCDVCLRKESACFGKSDPIFEGKNVLAIVVQHLDLKITLTRVCQHCWSKLEAFDEFYRMVNEQHHFHKPLKIDPSDDVIGMEFVEIKHEPLVEEDKDLMVKEEKEPLPNTECDKLLPEHSMSVDNDEENLKNENTNYASSDESEDSYTPPNPTRSAGKPTVKKEPKVDTEILDFYKRLVCEVCDAERMLAGEPSIEYGNLRELNKHMRKMHDHVIATSIKCPMCDKKLRYRAKLLEHRDMHLNPERFRCVVCQEVHQNMAEHMKNKHQERTYCCEECGKRFPFKARLTAHVKKMHTTKDVVCDQCQKSFSKYTIDDHKRAVHESKFICEHCPRTFKSRFSLEQHMEEHVEGLRKSMAATCDKCGVVLRDKYTLQSHIKRMHTEHPPVSCVSCGKVFKSKHNLNAHLANVCTERSFPCHICGKQFKKKIKLKEHMTTHTKSALYQCPYCPKTFSFETQLYTHRKQKHYEQWLEMQRKRKEGVRFKVNRVSDMPAIELVLVLVENITLNSCAITMATKCEVCFSTTECNMKEIFSDENKHIVEIIAKHLWFEVVQTAVDTWVCIKCWDALQEFHKFYCEVETSRQQQAARALIDKDEEDVSGSLEPKYSTEFFEVKVEPGELLDNTVEEDVNCADEKAVHCAFVKCEESMEIDPTAPTSDEEALQDNKSDSSSTDGMKNRLKKKSKRLHTVEEAAKQGKSIAQKEEDESLINFYKRIVCEKCDNQRMMVGEPQIDFGTWRALLRHTKEIHKHDKVYVKCPLCDLKLRTKQTLIQHKDCHENPEKYRCSLCNEIHQNMKEHLQNKHQERQFCCEVCGKKFPFKNRLTVHMKKMHVEKDIICDQCQKPFTKYTIEDHKRSVHSARFVCEHCPKTFNSRFRLLKHMEEHDESLRNSTSVPCTICGQVMRDKYILTRHIKLMHSVQPSVSCTTCGKTFKCKRNLSVHMTNVCMEPTRLFPCTICGKEFRRKNKLKEHMSTHTGKPLYKCSFCPETFRQDTHLYYHRKNVHYDQWLKMQQQQTTSYRNSKLLFQLQPISTMEATIRQCRTCLSISECDYLSIFAEENRTKKIDTVIAAHLWFEVVATSESQWICQSCWCKLEEFHEFYISIKETHEQRTTPGDSDSVTAKATSDSPPICNGPTYSTEFLEIKGEPFDIEEFDEDGYSLGGSSPCDKRLSCDDIKSEESDESESDSAQPQDEGTKKSEKFTRSRGSRASRQATGERLAKRKAGGRFPADPEEDKNILQFYKRIVCEVCDNKRMMVGEPLIEYATWGELLRHTKELHGHYKIFVQCPVCEMKLRTKVTLVQHMDMHQNPDKYRCEVCGEVFQNMKEHMQNKHEERQFSCDLCGSKFPFKKRLVVHMKKMHAEKNVTCDQCQKSFTRYTIEDHRRSVHMARFVCEHCPKTFKIRFRLHKHMQEHDKSLRISTSVPCPTCGQVMGDKYILRQHIKHMHNEQQAVDCETCGKTFKNYRNLKIHLTNVCMKPIQLHPCAICGKQFRHKNKLKDHMASCTPN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -