Afon002275.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles fontenillei
Gene Symbol
RREB1
Assembly
GCA_008817895.1
Location
VTWG01007434.1:1-7266[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.0034 0.19 12.0 0.8 1 23 230 252 230 252 0.98
2 11 0.00041 0.023 14.8 0.9 1 23 268 290 268 290 0.97
3 11 1.5e-05 0.00084 19.4 5.2 1 23 296 318 296 318 0.98
4 11 0.066 3.8 7.9 4.0 2 21 494 513 494 514 0.94
5 11 0.0051 0.29 11.4 0.1 1 23 756 778 756 778 0.98
6 11 5.7e-06 0.00032 20.7 0.6 1 23 787 809 787 809 0.99
7 11 0.00052 0.029 14.5 2.0 1 23 815 838 815 838 0.97
8 11 0.0011 0.06 13.5 2.1 1 23 1404 1427 1404 1427 0.95
9 11 9.7e-05 0.0055 16.8 0.3 2 23 1868 1889 1867 1889 0.97
10 11 0.49 28 5.2 5.4 1 23 1895 1918 1895 1918 0.96
11 11 3.8 2.2e+02 2.4 1.6 1 23 2082 2105 2082 2105 0.85

Sequence Information

Coding Sequence
ATGGACGTTGAAAGTAGTAGCGTGGCGAGTGCTGCCCCCACGACAACTCCCATCGGACTTGGCACCACTGACGGTGGGTATCTGTGTGCGGTGGTCAAAGCCGAGCGGCCGGAGGGCACAGAGTCACCGCTAAGCGCCACAGAGCACTGCGCAGCCGATGGGATGGCGTTAGCGTCGGCGGAAGCagtatcgtcatcatcgtctcCGGCCGACGCGCTCGAGGTCGCCAAACATTCCGCGGACAGTGGCGATGAGGAAGTCGtcggcaacagcaacaacagcacggcGGCGGCACTGCTGACCGAAGGACACAGCCGCTTTCATCAGGCCCGACAGCAGCGccacagtagcagcagcagcggcggcggcggcggcggcagcggaagcagcagcaatcggcAGCGGGGCGAGCATCTGCACCAGCTCACCGACGACATGCTGCGGCGGAAGACgatgaacaacaacagcagcaccgtgccgaacaacaacagcagcagcagcagcaaccgcggAGGTGTCGGCAAGCGGTCGCTCGAATCGACGGCggagatgctgctgcagcagcagcggcgccAGGCCGCGGCTGGCGGCTCCTCCACGGttggcaagcagcagcagcagcagcggcgcgccgacgacgaggacgaggaagaCGCCGAGCGGACGACGCCGGCAAAGACGCCCGAGTACACCTGCCCGATCTGTAACGCGGTGTCGCACACGCAGCGCGCCTTCACCGATCACCTCCGGCTGCACAATGCCGAGTCCGAGTCGGCGGCGACGGCCGTCGCGTCCGCCACCTTCTGCTGCAAGATCTGCTCGAAGGTGCTGTCGTCGGCGTCCTCGCTCGACCGGCACGTGCTGGTGCACACGGGCGAGCGGCCGTTCAACTGCAAGTACTGCAGCCTCACGTTCACCACCAACGGGAACATGCACCGGCACATGCGCACCCACAAGTACCCGTCCGGGCGGGACAGCTTCGAGAGCGATGCGGGCGGCGTCGGCACCGTCGGCACTGGCGGCGGCGGGTCCTCGTCCGATGGAAGTGGCGGCGGTGGACACAAAGCTGGGCGTGGACGCGGTGGTCCACCGGCAGGTCGTCACTATcgcaagaagaaggaggaggaggaggtggacgaggacgaggacgccgacgaggaggaggactaCCGGCAGCCAAAGAAGAGGAAGCGCGCCCTGTTTGATGccggcgagcagcagcagcaggacgagcACGAGGGCGAGTTCGAGGAGGGCGACGAGGAGCTGGTCGGTGGCGGCAAGCGGAAGGCGACGCTGGGAGGCGAGCGGACCGCGCAGCAGTATCGCAAGGTGcgcaccatcaacaacaacctgCTCGAGGGCTCGGTGGTGGAGAGCGGCCAGCGCTACTGCTGTCCGGTGTGCGTGCGGAACGATTTCGCGAGCATGCTCAGCCTGGAGCAGCACCTCGACCGGGAGCATCCGACCATCCCGGCCAAGTGCCGGCACTGCGAGATCGTGTTCCGCAGCCACAAGGCGCTGAATGCGCACCggtgcagcaacaacaactaccaGAACATTACGCCCGGCTTCAAGGATCTCACGTTCGTCGACTTTTCCAGCGAGAAGTTCCCGCTGATCGCGAAGAACCTGTGCGAGCAGAGCATCCGGACGCCGGTCACGAGCCAGAAGTACGAGTGTGGCCGCTGCTACCGGGCCTTCCCGTGCTCCAAGACGCTCTCGATGCACTCGGCCGACTGCTGCGGAGCGGGCAGTGGAGAGCGCGGGGCCGCCCACGCCGGAGGGCGCCGGCGCAAGCGAAACCGCTCCAGCACGGTGTCGGAAGCCCCGACGACGCCCTCCTCCCTGGACAAGTCGTTCTCGTCGCCAGTGCCGGCCCTGAAGCAGGAACCGCTCGCTTCACCGACCGGTGCCGGcacgaccaccaccgcccTGCCCTCCTACTACTCCTCCAACGTGGCGCTCTACCacgcgcaccagcagcagcagcagcagcaccagcagatGGTCGACAGCGGCAAGGATCTGGCCGACATCCAGTCCATCCTGAACGTGACCAAGCTGGGCGGAGGCGTCATCGGCCGCCAGCTGGACGGGGGCAGCCAGACGCCCCTGTCCGGCCTGCTGGACGCGGCCCTGCTCAAGGACGGTGCCGGCAGCGACAGTGGCATGTACGCCCACTCGACCGGGTCGCGCGACGAGCCGGAGGAGGCGCAGGACGCGTTCACGGCCGAGTTTCGCCGCATGAAGCTGCGCGGCCAGTTCCCGTGCCGCATCTGCACCGCCGTCTTCCCGAACCTGCGCGCCCTCAAGGGGCACAACCGGACGCACGTGTCGGCGGCCGGCCCGGGCCCGTACCAGTGCAACATGTGCCGGTACGTCGTGAGCGACAAGGCGACGCTCGTGCGCCACATGCGCACGCACAACGGTGACCGGCCGTACGAGTGTGCGATCTGCAACTACGCCTTCACGACCAAGGCAAACTGCGAGCGGCACCTGCGCAACCGGCACGGCCAGACGACGCGCGAGGACGTGAAGCGCGCCATCATCTACCACCCGTCCGAGGATTCGTCCTGCGACGATCCGCTCAAGAAGCTGCAGCTGTTCAACACGCCGCCGCTCGACGGTACCTACACGCCGGGGGCGATGCTtgcgggcggtggcggtggtggtggtgccgccTATCAGGACGAGCTGGCCGAGGCGCGCAGCAGCACGCCGCTGCCGTCGCAACAGCTCAAGGACATGCTgatgccgccgctgccgcttAGCTttgtgcatcatcatcatcatcccctgCTCGACAccagcctgctgctgcagacGCCCCCGAGCGGGGGCGGCGGCAACGGTGCCGGCGGTGCGTTCGGCTCAAGCGTGGCCGCCAAAATACAGGTGAAAAGCTTGGAAAAGCTGAACCAGCTAACGCCCCCGCAGGACGAGGACGATGCGctcgacgaggacgacgacgaggggcaagaggaagaggaggaggaggaggagcaggagcaggaggagcacgacggcggcggcgagCCGTTGGAGCAAAAGCCGACACTGTTGGGCAAGAAGGCGTCGGCAGAGGACGCAGCCGTGCCGTCGCACCGTGCCGGAAAGCAGTCGGCAGTGGAGGCCGCGACCGTGCACCCGCGGCCAATCGATCTGAGTATGGATGCGCTCGATCTGAGCAAGAAATCGACCGTCGCAGGTAACCGCaaggccgccgccgccgccgccccgaCACTCTCGACCGACggtgaggaggaggacgatgacACGATGGCGGCCCAGCTGCACCAGCTGCGCCACCAGCAGCGCGGCCACAACGGGGTGGAGGGCGAGGCGCGCAAGCATGCGGCCAGCGGCGGCACCAAAGCTCAGCAGCCGCTGCCGAAGGAGCCGGCCGAGCTGGACGAGGGCAGGGCGGAGCTGCCCAAGCTTTCCAAGGTCAAtctcgcccagcagcagcaacagtttcAGCTGTTCAACGACACGTTCGCGAAGCTCGATCCGATGAACTTCTTCCAGTTCTACCAGCTGTACAACTCGCTGCAGCTGCCCTCCTTCCCGCTGCACGCGTCCCCCTTCCTGCAGAACCACATGCTGGCGGGGTCGGCGGCCGCGCTTGGCGAGCTGTTGAGCAAGGACTTTGGGCTCGGCGCACTGCCGAACCTTGCCGCAGCGGCGGCTGTCTCGGCGGCTGCCGCCTCGACGGGCGGCagtggcggcagcggcggcgtcGGTCGCAATCCCCACCATCCGCTGCTGGGGAACCCGTTCTACCCACCGCCGCTGACCGATACGCCCCCGAACAGCGTCACCAAGTCGGGCGACTGTCTCGAACTGGGGACGGCCGCCACCGTGCCCACGCCGAAGCAGCTGCTAACGCCTTCCTCGCCATCGCCGCTGGCGACACCGATCGACGGTGGTAGCGGGTCGGGCGGCAGCACCGGCCTGACCAACAAGCAGCTCTcttcgctgcagcagcagcagcagcatcgcggGGCCAGCGGGTCGCCCGTCTCCTCCTCTGCAGcactggcggcggcggcggcggccgctgcagccgctgcGGCCAGCTTTGGCGTCTCGGCCAGTGGCGCTAGCGGACCCGGTTCGGCCGGCGTCGGTCCAGTGAAGATGGTGATCAAAAATGGCGTCCTGATAccgaagcagaagcagcgcCGCTACCGCACCGAGCGGCCGTTTGCGTGCGAGCACTGTTCCGCGCGGTTCACGCTGCGCTCGAACATGGAGCGGCacatcaagcagcagcacccgcaGTTTTGGTCCCAGCGGCAGCGCGGCGGCCATCTGATGCGTCGCAGtgccggcggcggtggaggaggaggaggaggaggtggaggaggagcaggatcCGGTAGCAATAGTAGTGCGAGCATGGTGGCGGCTGCCAACAGCTCCGTCGGTTCGCTGGTGTCCGCCCTCCAGGGCGCTTTCGGTGGGGCAGGTATGCACGGTGGCAATGCGGGAGGCGGCGCGGGCGCCATATCGGACCAGGTGAAGTACGCCATCCTGGCCCAGCAGTCGGGCAAGGGGTCGGGCGCTATGCGCGCGCGCGGCGAAaccgaggaggacgacgaggaggaagacgaTCGGGGCCAGGAGCGACCGTACGAGGGGGCCACACCGATCGTGGGTCAACGGTAccgtcgccgtcgccgccggCTGCAGTCGCATCTCGAACAGGACAGCGAGTTTCTGCGCCGCAGCTACGACGAGACGAACGCCTATCGAATGGCActgaaggaggaagaggaggaggaggaggacgatgaggaGCAGACAGTAAGGCAGGAACAGCGGGAGGCACTGCtagaggagcagcagcagcagcactacgaCCAAGAGCACgatgaagaggaagaggaggaggaggagggtgcAGCACCAGGTGCGCTGGAAGAAggcgacgaggaggacgaggaggaagatgCGCAGCTCGTGATTGACGAGGAAGAGCGGGACGAGTGCGGGGAGAAGAAGATGGCGAAGTTGCAGATGCAGGATGTGCCGCCCACGCCGGCCACCTCGGAGCAAGAGCTCGGACCGACCGGCGGTAGCGTTGgtcacgagcagcagcagcacggcagcACCTTGAACCGCATCCTGAAGCAGAAGCTGGAAGAGCATCGCTCAATCGGGGACGCTGGGGAGACTAATAAGGGACAGGAACAGAAGCCGACAGTGCCGCAGCAGCTCGCAGGCAAGTCgtcgaagcagcagcatcaatcGTCGGCGGCTACCGGTTCGGCCACCGGATCCCGCAAGGCATCGTGTGGCAGTACCGGCAGCGTGACCAATGCCGACGAAGCTGGCAACGCGAGCAGCGACCTGGTGCCCGTGTCGAAGCTGCTCGACAACGCAACGAACCCCGCGCTGGAAAGCTACTTCAGCCGACCCGAGGTGCAGGTGCCACTGTCGCAGGATCACAGCGATGAGGAGGGCCTGGTGGCATCCGGGTCCGCGTCCGAGAGCAACAACTCCGGCACGGACGACCCGAACCCGTCGGCGGTGGCCCTCGCGCACcaggagcagaagaagaagtcgGCCTACAGCCTGGCGCCGAACCGGGTCAGCTGCCCGTACTGCCAGCGCATGTTCCCGTGGTCGAGCTCGCTGCGCCGGCACATCCTCACGCACACCGGCCAGAAGCCGTTCAAGTGCTCCCAGTGCACGCTGCTCTTCACGACCAAGTCGAACTGCGACCGGCATCTGCTGCGCAAGCACGGTGACGTCGAGTCGGCCGTCTCCATACCGGTGCCGATCGACGATCTGCTCGATCCGAAACCGGAACCGAtcccggtggcggtggccgaAGCGATGTGCAAGATGATCACCGGCAAGGGCAGCCGGTCCgacgaagacgacgaaccGCAGGCTGACGCTTCCAACGAGGAGGCAAAAAACGAGCCAAAAAACGAAGGCAGTGGAAGGCGGGGCAGCAGCGTGGTGTCGGGCGATGCTGAGCTACCGCCAAAGTTTGCGGGCGACAAAAAGAATGGCAGTGAGGgagggcagcagcaggtggCGGCGCACCGGGAATCCGAGCAGCTGAAGGAAAATGGCGACGGCGAAGCGGAACCTgcccggcaccaccaccagccggaCCAGGAAGACGAGTCCGACGGTGTCGCCCGGGATACGGCGATGGAGGAGGAAGACGAGGGCAAGGAGGATGGCCGGTTATCGGCGGCGGGAGGCTTCTCCGATCTGCCGTACAAGTGCCACCTGTGCGATGTGTCCACCGCCGAGCGTGTGTCCTGCCTGGAGCACATCAAGCAGGCGCACCCGCAGGAGTTCACCACGCTGATGGCGAAGGTGTCGCTGGAGACTGCGTCCGCGTCGGCGACCGAGAGCGAGGCGCACACCGGCTCcccggacgacgacgagagtggcaccaacaacaacaataacaacaacaacaacaataataacaacaacaacaacaacaacggtggcAAGTATCTCGACTATGCCAATCGGAAG
Protein Sequence
MDVESSSVASAAPTTTPIGLGTTDGGYLCAVVKAERPEGTESPLSATEHCAADGMALASAEAVSSSSSPADALEVAKHSADSGDEEVVGNSNNSTAAALLTEGHSRFHQARQQRHSSSSSGGGGGGSGSSSNRQRGEHLHQLTDDMLRRKTMNNNSSTVPNNNSSSSSNRGGVGKRSLESTAEMLLQQQRRQAAAGGSSTVGKQQQQQRRADDEDEEDAERTTPAKTPEYTCPICNAVSHTQRAFTDHLRLHNAESESAATAVASATFCCKICSKVLSSASSLDRHVLVHTGERPFNCKYCSLTFTTNGNMHRHMRTHKYPSGRDSFESDAGGVGTVGTGGGGSSSDGSGGGGHKAGRGRGGPPAGRHYRKKKEEEEVDEDEDADEEEDYRQPKKRKRALFDAGEQQQQDEHEGEFEEGDEELVGGGKRKATLGGERTAQQYRKVRTINNNLLEGSVVESGQRYCCPVCVRNDFASMLSLEQHLDREHPTIPAKCRHCEIVFRSHKALNAHRCSNNNYQNITPGFKDLTFVDFSSEKFPLIAKNLCEQSIRTPVTSQKYECGRCYRAFPCSKTLSMHSADCCGAGSGERGAAHAGGRRRKRNRSSTVSEAPTTPSSLDKSFSSPVPALKQEPLASPTGAGTTTTALPSYYSSNVALYHAHQQQQQQHQQMVDSGKDLADIQSILNVTKLGGGVIGRQLDGGSQTPLSGLLDAALLKDGAGSDSGMYAHSTGSRDEPEEAQDAFTAEFRRMKLRGQFPCRICTAVFPNLRALKGHNRTHVSAAGPGPYQCNMCRYVVSDKATLVRHMRTHNGDRPYECAICNYAFTTKANCERHLRNRHGQTTREDVKRAIIYHPSEDSSCDDPLKKLQLFNTPPLDGTYTPGAMLAGGGGGGGAAYQDELAEARSSTPLPSQQLKDMLMPPLPLSFVHHHHHPLLDTSLLLQTPPSGGGGNGAGGAFGSSVAAKIQVKSLEKLNQLTPPQDEDDALDEDDDEGQEEEEEEEEQEQEEHDGGGEPLEQKPTLLGKKASAEDAAVPSHRAGKQSAVEAATVHPRPIDLSMDALDLSKKSTVAGNRKAAAAAAPTLSTDGEEEDDDTMAAQLHQLRHQQRGHNGVEGEARKHAASGGTKAQQPLPKEPAELDEGRAELPKLSKVNLAQQQQQFQLFNDTFAKLDPMNFFQFYQLYNSLQLPSFPLHASPFLQNHMLAGSAAALGELLSKDFGLGALPNLAAAAAVSAAAASTGGSGGSGGVGRNPHHPLLGNPFYPPPLTDTPPNSVTKSGDCLELGTAATVPTPKQLLTPSSPSPLATPIDGGSGSGGSTGLTNKQLSSLQQQQQHRGASGSPVSSSAALAAAAAAAAAAAASFGVSASGASGPGSAGVGPVKMVIKNGVLIPKQKQRRYRTERPFACEHCSARFTLRSNMERHIKQQHPQFWSQRQRGGHLMRRSAGGGGGGGGGGGGGAGSGSNSSASMVAAANSSVGSLVSALQGAFGGAGMHGGNAGGGAGAISDQVKYAILAQQSGKGSGAMRARGETEEDDEEEDDRGQERPYEGATPIVGQRYRRRRRRLQSHLEQDSEFLRRSYDETNAYRMALKEEEEEEEDDEEQTVRQEQREALLEEQQQQHYDQEHDEEEEEEEEGAAPGALEEGDEEDEEEDAQLVIDEEERDECGEKKMAKLQMQDVPPTPATSEQELGPTGGSVGHEQQQHGSTLNRILKQKLEEHRSIGDAGETNKGQEQKPTVPQQLAGKSSKQQHQSSAATGSATGSRKASCGSTGSVTNADEAGNASSDLVPVSKLLDNATNPALESYFSRPEVQVPLSQDHSDEEGLVASGSASESNNSGTDDPNPSAVALAHQEQKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSQCTLLFTTKSNCDRHLLRKHGDVESAVSIPVPIDDLLDPKPEPIPVAVAEAMCKMITGKGSRSDEDDEPQADASNEEAKNEPKNEGSGRRGSSVVSGDAELPPKFAGDKKNGSEGGQQQVAAHRESEQLKENGDGEAEPARHHHQPDQEDESDGVARDTAMEEEDEGKEDGRLSAAGGFSDLPYKCHLCDVSTAERVSCLEHIKQAHPQEFTTLMAKVSLETASASATESEAHTGSPDDDESGTNNNNNNNNNNNNNNNNNNGGKYLDYANRK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00102568; iTF_00093723;
90% Identity
-
80% Identity
-