Basic Information

Insect: Anopheles fontenillei
Gene Symbol: zfh1
Assembly: GCA_008817895.1
Location: VTWG01007406.1:38554-54854[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.22 13 6.2 0.2 2 23 53 75 52 75 0.95

2 8 5.9e-05 0.0034 17.5 0.7 1 23 251 273 251 273 0.97

3 8 6.6e-05 0.0037 17.4 0.5 2 23 280 301 280 301 0.97

4 8 1.6e-05 0.00092 19.3 7.1 1 23 310 332 310 332 0.99

5 8 1.8e-05 0.001 19.1 0.8 1 21 338 358 338 359 0.95

6 8 2.4e-05 0.0013 18.8 4.0 1 23 1269 1291 1269 1291 0.95

7 8 0.00012 0.0068 16.5 7.8 1 23 1297 1319 1297 1319 0.98

8 8 0.065 3.7 7.9 7.0 1 21 1325 1345 1325 1346 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.22	13	6.2	0.2	2	23	53	75	52	75	0.95
2	8	5.9e-05	0.0034	17.5	0.7	1	23	251	273	251	273	0.97
3	8	6.6e-05	0.0037	17.4	0.5	2	23	280	301	280	301	0.97
4	8	1.6e-05	0.00092	19.3	7.1	1	23	310	332	310	332	0.99
5	8	1.8e-05	0.001	19.1	0.8	1	21	338	358	338	359	0.95
6	8	2.4e-05	0.0013	18.8	4.0	1	23	1269	1291	1269	1291	0.95
7	8	0.00012	0.0068	16.5	7.8	1	23	1297	1319	1297	1319	0.98
8	8	0.065	3.7	7.9	7.0	1	21	1325	1345	1325	1346	0.96

Sequence Information

Coding Sequence: ATGGTGTCCTGCAGCGTTGCTGTGTCGACGTACTACAACGCGGAAGGAAGTATCATGCCATCTTCGACCAAGTTTTCCCTGCAATTTCCTTCCTTGCCATCCGGACTACCGAAGGACAGTGAAAACGATGCACTAGCGGACAGCGATTGCTGCGTTCAGTGCCCTCAGTGCCACCAGACGGTTCAGGGAATCGAGGCACTGAAAGAACACATTCAGCTTAATCACAGCGGCTGCCCGAACGGCCGGAGGGCAAAGTTCCCGACCGATACTAGCGcaccggacgacgacgacgaagacgacgtagaggacgaggacgacgagcgCATGGCGGAGGAGGACGAACATCACGTCGATCCGGAGGCCGTGTCGCCCCTGCCGGCCCCGCTCGATTCGCTCGCGGCCAGCGCGGTGGCGGGCGCACGGGCCACCGGCGATCTGGTCGGCAGCCGGCTCCAGGCCAAGTGTGGCAGCCTGctgcagctccagcagcagaagcaccaGCTGGCCCAGCTGGTCGACGACcgggaggacgaggaggaggagctaGAGGTGGCCCAGGGAGGCAGCTCGCCGCGCGATCTGCTAATGGCGGGGCTGGCCCCGCAAACCGTACCGGCGGCCGACCGGTCGTACGGACCGCGATCGATGGTGATCAGCCCGGCGCaggacggcagcagcaactcaAGCAGCGGGCCGAGCCTGCCGACCGGCGGCACCACCGTGAAGGAGAGCGGTGCCGAGCTGGCCGTGTACGAGTGTGCCCAGTGTCCGACCACGTTCGCCAGCCGGGATCAGCTGGAGCGGCACGAGATGCATCACGCACCGTCGGCCGATGCGAGCTGCAAGGTGTGCAACAAACCGTTCGCCAACGTGTACAGACTGCAGCGCCACATGATCTCCCACGACGAATCGTCGCAGCGGCGGAAATTCAAATGCAACGAGTGTGATAAAGCGTTCAAATTCAAGCACCATCTGAAGGAGCACAAGCGCATCCACTCAGGCGAGAAGCCGTTCGTCTGCCCCAACTGCGGCAAGCGCTTCTCGCACTCCGGCTCCTACTCGAGCCACATGACCTCGAAAAAGTGCATCAATATGGGCATCAGGctcaaccacaacaacaacaacaacaacaataacagtagcagccacaacaacaataacaacaacagcaccagccacaataacaacagctCCAACAACAGCGGTAGCGGCAGTGACAGTAACCACCGATCGCCCCAGTACCCGTTCCACGGTGGCAACGGGTTCACCGGCATCCCGAACGGGCATCCCGGTGCAATAGGCACTGGGGGGCTTGGCCGTTCGCCGATCGGTCTGCTACCGCAGGCGGCCCTCCATCGCGATCTGGACATTGCCGGACGGCTCCGCCTAGTGACGTCACCGTCGCCCACCTCCTCCTGTTCCTCCGCGACCAAGCACGAGCTGGACGCGATCGGTCCGCAGCCGGGCGGTGTGGACCCGCTGCTGCTCACCAAGATACAGCAGGCGTCCTGGCTCGCCGTCGCCATGCACAACATGCAGGCCATGTGGGATCCGAACGTGCTGCGCCTGTTTGACCAATTCCAACAGCAGCCACAGTCGACGTCGTCGTCTACTGACAGTGAAACGCACGAGCCTATGGAGGAAGGctcgcaccagcagcagcaccagcagggaccgccacaaccaccaccaccgccgccagccACAACCTCGCTGCTTGGCGACGAGGATGAGCAGCGGCCAGAATCGGCCCGGCGGCCTGCTTCGTCGATCGATGTCGTCTCGATGCCGGAAGGCGTCACCCAGCAGAACCCGTCCGAACGCATGGAGAtcgacgaagaggaggaggagcacgAAGAGGACGAAAGCTGCGCGGAGGAGAAGGTTGAGGTCGTGATGGGCTCGAGCACAGCCGGTAGTCGGCAGTCTCCGGCCGCCTTTCACGAGGATGCAATCCAGAAAAGCGCCGACAATGGCTCCGCTGTAGAGGAGCAGGATAGGGAGGAGTCGTCGCACCAACCACAGAAGGACGAATATCCCGAGGAGCAGCAATCTGCTGAGAGCAAGCTGATTTTGCCGCTGCTTCCCAAGCAGGAACCACTAGACGAACCGGCAATGGAGTCTACCAACTCGATGGAatcgcagcagcaccagcagcagcagcaacagcagcagcaacagcagataCAAGAACAGCTGACGTCATCTGTCAGCCATGACACGCTGTCCGTCGTGAAAGATGAACCGTCCGAGGAGACTGCCATCGACCCATCGCTGGAGCTGTCCGACGAGCCCAAACTGAACGAGCGGGACATGGAACGGGCGCACTTCTCGTCGCCCTCGGCCGCATCCTCCCTCTCGCCCTCAGTTTCCACTGCTCCGCTGCACTGCATCTACTGCAGCGAGGAGTTTGCGACCGAGCCGGAGATGCTGCAGCACGCACGGATGTTCTGCAAGCGCTCCCTGCTGCTCAACCCGTTCATGAGCGCGTCGGGTGCGCTGGCGCAGACGGGCAACGGTGTGCCAGCGGGTACGATCACCGGAGGCGGtggcatcagcagcagtagcagtggcaacagcagcaacagcagctgcagcgacGACGACACCGACTACGATACGGTTGCACTCAAGGGCGACTGCGGCGGTGCGTACGGACTGCACGGTAGCATGGCCGGCGGTGCACTCGGTGTCGGAGGACCGCACGGTGGACCGGGTGGCAGTGGCAAGGTGCGCGTCCGCACCTCCATCTCAGAAGAGCAGCAGAACGAGCTGAAGAAGTACTACGCCCGCAACAGCAAGCCGAGCCGGGACGAGTTCCAGGCGATCGCCCAGCACGTCAAGATGGAGGCGCGCGTTGTGCAGGTGTGGTTCCAGAACAACCGATCCCGGGAGCGCAAGATGGGCGTAaccggtggcagtggtggtgtcGGTGTCGGTCGCCAGTATGCAGCGGGTGGTGGTCAGGCCGGCGGCCAGACGGTCGCCCCGGCAGGGACGCCGAACTCGCCGCTGCACGCCGACCGTGCACCGTCGGTCGTAACCGGGCAGGACGCGACTGGCGACCAGCCGCTCGACCTATCCGTCAAGAAGGGGCTGCTCACGGTCGGTGAGGCGCTGCTGAGTGCCGCCACCAACTCGCAGGCCGCCGCCACGGCGCTGGCCGACGGCTCGCTTCCGGCCGTGCTGCTCCAGGCTGACACCATGTCCGCGCTGAACGAGGCGATCAACCTCAGCATCAAGGCGTCCTGTTCAACGACCCCCTACTTCTACCACGACATACACCCGATCCACGGCGTTACGGCCGGACCGCAGGCGCACGCCATGCTTGGCCTCGGGACCGGGCTGCCGCGGGACACACCCTCGCCCCAGGACGGCCGGGGTCAGCACACGGCAGCGCCGTCGCTGCCGTCCCAGCCGTCGCCGCACGCGTACGGAAAGTATCCGCCGATGCACGGGCTCCAACCGCCGCACCATCCTGTCAGCCTGGCCGGCATGGACCAGCTGTTCCGCAAGTACTCGCCGAGGCTGGCAGCGGCGGTGTCGACCGCGGCCGCCACCGGTACGATGGTTGGCCGGGCCAGCCTTAGCCCGGGCGCGCTCGACATGATGCCGGACGAGACTGGCACGAGCTACTACGGCGCCTTCCCGGACAAGAAGCACCTGCTGCAGTCGATGCTGAACGTGCCCAAGCGGGGCGCCGGGTACGGGCTCGGTGGAGGTGCTGGCAGTGGGGCAGCGACCGGTGCCGGCGTCAAGGATGCCGGCTCGCTGGCCCACCCAGCCCCGGATGCCGAGGGACAGTACGTCTGTGATCAGTGCGACAAGACGTTCAGCAAGCACAGCTCACTGCAGCGACACAAGTACGAACACTCAGGTCAACGTCCTTACAAGTGCATGGAATGTCCGAAGGCGTTCAAGCACAAGCACCATCTGACCGAGCACAAGCGGCTGCACAGTGGGGAAAAGCCGTTCCAGTGCTGCAAGTGTCTGAAGCGCTTCTCGCACTCCGGCTCCTACAGCCAGCACATGAACCATCGCTACTCCTACTGCAAGCCCTACAGGGAGGGCAAATAA
Protein Sequence: MVSCSVAVSTYYNAEGSIMPSSTKFSLQFPSLPSGLPKDSENDALADSDCCVQCPQCHQTVQGIEALKEHIQLNHSGCPNGRRAKFPTDTSAPDDDDEDDVEDEDDERMAEEDEHHVDPEAVSPLPAPLDSLAASAVAGARATGDLVGSRLQAKCGSLLQLQQQKHQLAQLVDDREDEEEELEVAQGGSSPRDLLMAGLAPQTVPAADRSYGPRSMVISPAQDGSSNSSSGPSLPTGGTTVKESGAELAVYECAQCPTTFASRDQLERHEMHHAPSADASCKVCNKPFANVYRLQRHMISHDESSQRRKFKCNECDKAFKFKHHLKEHKRIHSGEKPFVCPNCGKRFSHSGSYSSHMTSKKCINMGIRLNHNNNNNNNNSSSHNNNNNNSTSHNNNSSNNSGSGSDSNHRSPQYPFHGGNGFTGIPNGHPGAIGTGGLGRSPIGLLPQAALHRDLDIAGRLRLVTSPSPTSSCSSATKHELDAIGPQPGGVDPLLLTKIQQASWLAVAMHNMQAMWDPNVLRLFDQFQQQPQSTSSSTDSETHEPMEEGSHQQQHQQGPPQPPPPPPATTSLLGDEDEQRPESARRPASSIDVVSMPEGVTQQNPSERMEIDEEEEEHEEDESCAEEKVEVVMGSSTAGSRQSPAAFHEDAIQKSADNGSAVEEQDREESSHQPQKDEYPEEQQSAESKLILPLLPKQEPLDEPAMESTNSMESQQHQQQQQQQQQQQIQEQLTSSVSHDTLSVVKDEPSEETAIDPSLELSDEPKLNERDMERAHFSSPSAASSLSPSVSTAPLHCIYCSEEFATEPEMLQHARMFCKRSLLLNPFMSASGALAQTGNGVPAGTITGGGGISSSSSGNSSNSSCSDDDTDYDTVALKGDCGGAYGLHGSMAGGALGVGGPHGGPGGSGKVRVRTSISEEQQNELKKYYARNSKPSRDEFQAIAQHVKMEARVVQVWFQNNRSRERKMGVTGGSGGVGVGRQYAAGGGQAGGQTVAPAGTPNSPLHADRAPSVVTGQDATGDQPLDLSVKKGLLTVGEALLSAATNSQAAATALADGSLPAVLLQADTMSALNEAINLSIKASCSTTPYFYHDIHPIHGVTAGPQAHAMLGLGTGLPRDTPSPQDGRGQHTAAPSLPSQPSPHAYGKYPPMHGLQPPHHPVSLAGMDQLFRKYSPRLAAAVSTAAATGTMVGRASLSPGALDMMPDETGTSYYGAFPDKKHLLQSMLNVPKRGAGYGLGGGAGSGAATGAGVKDAGSLAHPAPDAEGQYVCDQCDKTFSKHSSLQRHKYEHSGQRPYKCMECPKAFKHKHHLTEHKRLHSGEKPFQCCKCLKRFSHSGSYSQHMNHRYSYCKPYREGK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00102265;
90% Identity: iTF_00093365;
80% Identity: iTF_00100864;