Basic Information

Insect: Anopheles fontenillei
Gene Symbol: Ctcfl
Assembly: GCA_008817895.1
Location: VTWG01011852.1:43518-45925[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.00078 0.044 14.0 3.0 1 23 162 184 162 184 0.98

2 11 3.9e-05 0.0022 18.1 1.0 1 23 190 212 190 212 0.98

3 11 4.6e-05 0.0026 17.9 7.4 1 23 218 241 218 241 0.97

4 11 4e-05 0.0023 18.0 1.8 1 23 247 269 247 269 0.98

5 11 1.2e-05 0.00068 19.7 2.2 1 23 275 297 275 297 0.99

6 11 0.0001 0.0059 16.7 0.7 1 23 303 325 303 325 0.98

7 11 0.00062 0.035 14.3 1.8 1 23 333 356 333 356 0.96

8 11 0.0011 0.061 13.5 1.5 2 23 363 384 362 384 0.97

9 11 0.0021 0.12 12.6 0.7 1 23 390 412 390 412 0.97

10 11 1.3e-05 0.00071 19.6 3.0 1 23 418 441 418 441 0.97

11 11 1.3e-06 7.3e-05 22.7 2.5 1 23 455 477 455 477 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.00078	0.044	14.0	3.0	1	23	162	184	162	184	0.98
2	11	3.9e-05	0.0022	18.1	1.0	1	23	190	212	190	212	0.98
3	11	4.6e-05	0.0026	17.9	7.4	1	23	218	241	218	241	0.97
4	11	4e-05	0.0023	18.0	1.8	1	23	247	269	247	269	0.98
5	11	1.2e-05	0.00068	19.7	2.2	1	23	275	297	275	297	0.99
6	11	0.0001	0.0059	16.7	0.7	1	23	303	325	303	325	0.98
7	11	0.00062	0.035	14.3	1.8	1	23	333	356	333	356	0.96
8	11	0.0011	0.061	13.5	1.5	2	23	363	384	362	384	0.97
9	11	0.0021	0.12	12.6	0.7	1	23	390	412	390	412	0.97
10	11	1.3e-05	0.00071	19.6	3.0	1	23	418	441	418	441	0.97
11	11	1.3e-06	7.3e-05	22.7	2.5	1	23	455	477	455	477	0.96

Sequence Information

Coding Sequence: ATGAGTTCGAAACGCATCAAACAGGAACCAAACACCAAGAAAAGGGCAGCGCAGCAAGACTCTGTTCCGGCGCCGATAAAGGAAGCGAAGCAGGAAAAGCTAGACATGGAGGACGTGGAGCTGATATCGGCCGGGctggaggacgacgacgaaggcGGGTGCTATTTCGTGGACCAGAAGGGCAACTACTACTTCCAAGCCAACGAGGACGCGGAGCTGACGGCGGTGGATGCAGGTCAAACAGAATTCGAGGGGCTAACAGACGAGCCGGACAAATCCGAGGAAGGTGTCAGCTACGTGCTGATCATGAATGATGCGGACAAGTCGACGCTCGTCCTAAATGATGAGCCGAGCCAGGGCGACAGTAAGGATAACGAGATCTACGATTTCGAAGATCCGGACTACATCGTGCAGGAAGAGCAGGAGCCGGCGAAAAAGACGCAAACGCGCGGCAAGCGCACTCAGCAGAGCACGGGCTCGACGTACATGTGCAACTACTGCAACTACACCAGCAACAAGCTGTTTCTGCTGTCGCGCCACCTCAAAACGCACTCCGAGGACCGGCCGCAcaagtgtgtggtgtgcgagCGGGGCTTCAAAACGCTGGCCTCGCTGCAGAACCACGTCAACACGCACACGGGCACGAAACCGCACCGGTGCAAGCACTGCGACAACTGCTTCACGACCTCGGGCGAGCTGATCCGGCACATCCGCTATCGGCACACGCACGAACGGCCGCACAAGTGCACGGAGTGCGATTACGCGAGCGTGGAGCTGAGCAAGCTGAAGCGCCACATCCGCACGCACACGGGCGAGAAACCGTTCCAGTGTCCGCACTGTACGTACGCGTCGCCGGACAAGTTCAAGCTGACGCGGCACATGCGTATCCATACCGGCGAGAAGCCTTACTCCTGTGACGTTTGCTTTGCCCGGTTTACGCAGTCCAACTCGCTGAAGGCTCACAAGATGATACATCAAGTTGGCAACAAGCCCGTTTTCCAGTGCAAACTCTGCCCGACGACCTGTGGCCGCAAGACGGATCTGCGCATTCACGTGCAGAATCTGCACACCGCGGACAAGCCGATCAAGTGCAAGCGGTGCGACAGCACGTTCCCCGACCGGTACAGCTACAAGATGCACGCGAAAACGCACGAGGGCGAAAAGTGCTACCGGTGCGAGTACTGTCCGTACGCTTCGATCTCGATGCGCCACCTGGAATcgcatctgctgctgcacacggaCCAGAAACCGTACAAGTGTGAGCAGTGCGCCCAAACGTTCCGCCAGAAGCAGCTGCTGAAGCGGCACATGAACTACTACCACGATCCGGACTACGTGGCGCCGACGCCGAAAGCGAAGACGCACATCTGTCCCACCTGCAAGCGCCCGTTCCGGCACAAGGGCAACCTGATCCGGCACATGGCAATGCACGATCCCGAGTCGACGATGAGCAAGGAGATGGAGGCGCTGCGCGAGGGCCGCCAGAAGAAGGTGCAGATCACGTTCGAGGAGGAGATCTACAAGGGCGAGGAAGACTACGAAGGGgaagaggacgaggaggatgaggaagaTGAATACGAGGGCGACGATACGGAGGAGGATgaagaggacgaggacgacgagctGGCAGCGGGACCGTTGGGTACGAGCGACGTCGTAACGGTCGAGGACGGGGACGGCCAGTACGTGGTGCTGGAGGTGATACAGCTGCAGGACAAAGATAGCAAAGCGGCCGGCATGGAGAAGTCGCGCAAGAAGCGGGGCGCACCGAAGCGAAAGGCAACGTCTCCACCCGCCGTCGCTACACCTCCGTCGACTTCCAGGGCGAGAACGGCCACGAGGACGGCGACCACGACAACGCGCGCGCTGCGGAGTGCGAAAAAAGAACCGGCGGAGTCGCTCGATATAGACGGAATAAATCTGGTGATGGTGACCGGGGAACCGGAGGACGAAAAGCACGAGATAGAAATCGAGCATCAGGGTGCCGACTCGGGGGATGAGTTTATCCTCTCCACGGAAGATTTGCAGGAAGCGGAAATGATGATGTCAACGTTTGAAGATACAAAGCGATCGCGCTATGATGTTACCATTAGCCAGGCCGAGCTGGAGAAAAACATGAGCAACTGCTTCGGATTCGATgacgatgatgacgaagaTTTAGACACCAAAGCAACAATAACGCTGCTGAATTAA
Protein Sequence: MSSKRIKQEPNTKKRAAQQDSVPAPIKEAKQEKLDMEDVELISAGLEDDDEGGCYFVDQKGNYYFQANEDAELTAVDAGQTEFEGLTDEPDKSEEGVSYVLIMNDADKSTLVLNDEPSQGDSKDNEIYDFEDPDYIVQEEQEPAKKTQTRGKRTQQSTGSTYMCNYCNYTSNKLFLLSRHLKTHSEDRPHKCVVCERGFKTLASLQNHVNTHTGTKPHRCKHCDNCFTTSGELIRHIRYRHTHERPHKCTECDYASVELSKLKRHIRTHTGEKPFQCPHCTYASPDKFKLTRHMRIHTGEKPYSCDVCFARFTQSNSLKAHKMIHQVGNKPVFQCKLCPTTCGRKTDLRIHVQNLHTADKPIKCKRCDSTFPDRYSYKMHAKTHEGEKCYRCEYCPYASISMRHLESHLLLHTDQKPYKCEQCAQTFRQKQLLKRHMNYYHDPDYVAPTPKAKTHICPTCKRPFRHKGNLIRHMAMHDPESTMSKEMEALREGRQKKVQITFEEEIYKGEEDYEGEEDEEDEEDEYEGDDTEEDEEDEDDELAAGPLGTSDVVTVEDGDGQYVVLEVIQLQDKDSKAAGMEKSRKKRGAPKRKATSPPAVATPPSTSRARTATRTATTTTRALRSAKKEPAESLDIDGINLVMVTGEPEDEKHEIEIEHQGADSGDEFILSTEDLQEAEMMMSTFEDTKRSRYDVTISQAELEKNMSNCFGFDDDDDEDLDTKATITLLN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00104550;
90% Identity: iTF_00104550;
80% Identity: -