Basic Information

Insect: Anopheles farauti
Gene Symbol: -
Assembly: GCA_000473445.2
Location: KI915040.1:1372123-1374587[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.15 8.6 6.6 0.2 1 23 179 203 179 203 0.96

2 9 0.42 25 5.1 1.0 1 23 242 266 242 266 0.96

3 9 0.17 10 6.4 0.3 2 20 283 303 282 306 0.90

4 9 1.4 84 3.5 0.1 3 19 314 330 312 330 0.88

5 9 0.00014 0.0084 16.1 0.3 1 23 342 364 342 364 0.99

6 9 6e-05 0.0036 17.2 2.3 1 23 368 391 368 391 0.95

7 9 0.031 1.8 8.7 0.2 1 23 397 420 397 420 0.95

8 9 0.016 0.92 9.6 0.4 1 23 425 449 425 449 0.98

9 9 0.051 3 8.0 0.7 1 15 457 471 457 481 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.15	8.6	6.6	0.2	1	23	179	203	179	203	0.96
2	9	0.42	25	5.1	1.0	1	23	242	266	242	266	0.96
3	9	0.17	10	6.4	0.3	2	20	283	303	282	306	0.90
4	9	1.4	84	3.5	0.1	3	19	314	330	312	330	0.88
5	9	0.00014	0.0084	16.1	0.3	1	23	342	364	342	364	0.99
6	9	6e-05	0.0036	17.2	2.3	1	23	368	391	368	391	0.95
7	9	0.031	1.8	8.7	0.2	1	23	397	420	397	420	0.95
8	9	0.016	0.92	9.6	0.4	1	23	425	449	425	449	0.98
9	9	0.051	3	8.0	0.7	1	15	457	471	457	481	0.89

Sequence Information

Coding Sequence: ATGGGGAAAAACACGGCAAAAAGAAAGCAACAACAAACTATCGTTACTTTCTTAACGAAGAAAATTAAAACCGAAGAGGAGCCCGCATCCGTCGGAACGGAAGAAGAGCAACAACCATCGTCGCATCCTGTGGTCTCAGATCCACCTGTGGCAAAGAAATTGGACGAAGCGGACGAGAATGATAGTGATGATGAGGAGATCAACGAATTGCGATCGAATGTGGCTGCATGGCTAAAACAACAAGCAGATAAGGAGCAAACGTTGGTAAACGAACTCCACGACGAAAGTCTGATCAGGCCCGATGATCCGGAAGAGCCAGAACAAGAGCAAGGTCGTGTGGACTTGACATTGCTGGAGACTAGAATTAACATTGCGTTGAAGAAGTACTCGGAAATCGAAAAACGGAAGAGTTTCAAGTTTGAATGTGAATGGGACAAGTGCAAAATGCTCACCGGTAACGAGCGGAAGTACTTTCACCATGTGGAATCACACGCTGAGGAAGCGATCAAACATGCGACAGATGACGTCGAACAGTACAGGTGCGAGTGGGATTTGTGCGATTTCGTGACGTCGGAAAGTGATGAGCTGATCGGGCATGTTCATTACCATGCGTACCACACGAAGCTGAAGGTGCACGGTGCCAGCATCCACTCGCTGCTGCGTCTCCCAAACTGCAACCTAGATAGCCGTATGCGCAACATCATCACCCACAAGAAGGTTACCTTCACCTGCGAGTGGTCGTCTTGCAACGAACGTTTCATGAAAGCGTTAGATTTTTTCTACCACGTACGGAACCACGTTATTGATGCATTTCCGGAGCAGCAGAGATCGAGCCAGGTACCGATCAAATGTCAATGGCCGCTGTGTAAGGTGGTTTACAAACATAGGTCAACGTTACTCGATCACGTATGGTTACACACCACCGAGCGGGAGATCGCGTGCTTTAACTGTGGCACAATGTTCTACGCACGTCAGAAACTCGTCGATCACTGCGCCCGGCAGATAGATATTACCCAACGTATGTACCAATGTGGTGAATGTGGCCGCATGTACGCAACGATGAATTTGATGAAAATGCACCTACTAACTCACGATAAGGCACACCAGTGCACAAAGTGTCCGTTGAAATTCGACACCAACTATGCATTATCGAGACACATGGCCTACCGGCATCTGAAGCAACGTAACTTCCAGTGCCAGAAGTGTGAATATGCGACATACGCCAAGCGCGATCTGTTGCTCCACATTCAAGCTGTCCACGAAAAGAAACTCTACCGTTGTGAGGAGTTTGGCTGCAACGTAGCCTACCATTCGGAAAGTGCAATCAAGCGGCACATCAACTGGCACTATAATCTGCCTCCGCCCACGTACGCCTGCCATCTGTGCGATAAACGCTACAATACGCATTCGTACCGTATTTCGCAGCACCTGCGCTTCGCCCACAAGCTGGAACGAGCTCCCGGAATGAAAGGTTTTCGTTACCGAGTTGACTTCGACGGTGTGTATCGGCTTGAATCATATGTTACCCCGCGCCTGATTGAAATGCAGCAGGGGTCCCAAACGAAGGAAGATAAAAAAATTGTGCCGTTTGCAACGAAGAAGAGGAAGGAGAAACGTGATGAAACCGTGGAGGAATCGCTACCGGAAACACATATTAAGGGAAGGCCAAAAATTAAGACAATTAAATCGATCGGTGAGCAAGAGTTTGCGATCGAGTTGGACATGGAGCCGACAGAAGCGGACCAAGCAGCGACGGACGATGGCGCTACTGGTGGCAATGACGAGCAGAAGCAGAAAGCTACGAAACCGGTAAAAAGAAATCGAGACAACTGGACGAATGATGATTCTGACAGCAACATCAGCAGCGACTCATCGACACCGCAAACCGATGCACCGAAGACGAAGGACGTGCAGGATTTTAAAGTTATGAAGCGATACTTGAAAATGGGTAAAAAAGTGGCTGAAAAGTAG
Protein Sequence: MGKNTAKRKQQQTIVTFLTKKIKTEEEPASVGTEEEQQPSSHPVVSDPPVAKKLDEADENDSDDEEINELRSNVAAWLKQQADKEQTLVNELHDESLIRPDDPEEPEQEQGRVDLTLLETRINIALKKYSEIEKRKSFKFECEWDKCKMLTGNERKYFHHVESHAEEAIKHATDDVEQYRCEWDLCDFVTSESDELIGHVHYHAYHTKLKVHGASIHSLLRLPNCNLDSRMRNIITHKKVTFTCEWSSCNERFMKALDFFYHVRNHVIDAFPEQQRSSQVPIKCQWPLCKVVYKHRSTLLDHVWLHTTEREIACFNCGTMFYARQKLVDHCARQIDITQRMYQCGECGRMYATMNLMKMHLLTHDKAHQCTKCPLKFDTNYALSRHMAYRHLKQRNFQCQKCEYATYAKRDLLLHIQAVHEKKLYRCEEFGCNVAYHSESAIKRHINWHYNLPPPTYACHLCDKRYNTHSYRISQHLRFAHKLERAPGMKGFRYRVDFDGVYRLESYVTPRLIEMQQGSQTKEDKKIVPFATKKRKEKRDETVEESLPETHIKGRPKIKTIKSIGEQEFAIELDMEPTEADQAATDDGATGGNDEQKQKATKPVKRNRDNWTNDDSDSNISSDSSTPQTDAPKTKDVQDFKVMKRYLKMGKKVAEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00103266;
90% Identity: -
80% Identity: -