Afar000295.1
Basic Information
- Insect
- Anopheles farauti
- Gene Symbol
- -
- Assembly
- GCA_000473445.2
- Location
- KI915044.1:5586572-5588255[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.034 2 8.6 0.8 2 23 169 191 168 191 0.95 2 10 0.97 57 4.0 2.3 6 23 200 217 200 217 0.98 3 10 2e-05 0.0012 18.8 0.6 2 23 224 246 223 246 0.93 4 10 0.0092 0.55 10.4 5.5 1 23 254 276 254 276 0.97 5 10 0.0008 0.047 13.7 0.1 3 23 281 302 279 302 0.94 6 10 4.7e-05 0.0028 17.6 1.7 1 23 308 330 308 330 0.96 7 10 0.11 6.4 7.0 0.3 2 23 340 362 339 362 0.95 8 10 0.0058 0.34 11.0 1.3 1 23 369 392 369 392 0.97 9 10 2.8e-05 0.0017 18.3 0.4 1 23 397 420 397 420 0.92 10 10 0.00059 0.035 14.1 1.1 1 23 426 449 426 449 0.96
Sequence Information
- Coding Sequence
- ATGGACGAAAAGTGTCGATTATGTTTATCTCAATTCGAAAACCTACAAGCAAGTGCAACAACCATCGAAGAAGATAAATTTAGGGAAAAACTAAAAACGGTATTTACTTTTCCGATCACAGCAATCGAGTCGTTTCCTTCGACAGTATGCCAACAGTGCGAGGAACAGGTGTCTGTGTTTCACTCCTACCACGAGCTGGTGAAAACCAACCAAGAACAACTGTGGGCACTCCAGCACCAAAAGTACATCGAGATGGTTAAGTCTGAGCCCAGTCTGCACGACGACTATGACTCATTCGAGGATAAAAGCGTGGAAACAGGTTTATGTAAGGTGGAGATCGTCGACGTCGATGAGGGTGCGCAACCTGCAAGGGTGGGCCAAAAGCGACGGGGTCGTCCGCGGAAAGGTGAAGTGAGAGAAAGCAAACAGTCAAAATCACCACCGAAGCGGAAGTACAAATCGATGGATGAAACGAACCAGCGGCTGCGCGAATTTTACGACATGAAGTGCGAGCTGTGTGATGAGAAGCTGGACTCCTTTACGGCGCTAAAGAACCACTACTACAAGCAGCACCAGGTGCAGGGTTACATCAAGTGCTGCGAACGTACGTTTCACAGCCGCTACCGGTTACTGGAGCATCTATCCAAGCATGTCGGTGCCAGCATGGTGCGGTGTGAGATTTGCGATAAGAACTTCAGCAGCCGAAGTTATCTGCTCGTCCACAACAGTCGCATGCATGGCCAGGCCGAGGATCGACCGTATAAGTGCACCCAGTGCCATCAGTCGTACGCGATGGAATGCCACCTAAAGGCACACGTAGTCTCGCACGTACGCGTAAATTGCACGGTCTGCGGGAAGGAGTTGGCCAGCTCTCTTTCCCTCCGCACGCACATGATCAATATGCACGGTAACAGAGAAAATCACATCTGCGATACCTGTGGCCGGGAATTCCGCAGCCGCCAGGCTTTCGAGCGTCACGTGAAACTGCACCTCGGGCTGGAGGTGACGGAGCAGGTGCAGTGCACCGTTTGCTCCAAATGGTTGAACAGCAAGCGGGCTCTGAAGATGCACGTCAAGCTGGTTCACATGGAGGCTGGCCAGACGTTCCAGTGTGATCTGTGTTCGCAACAGTGTCCCAACAGCCGGGCACTCGCAAGCCACAAGCAGCGTGTGCACGTAGAGGAACGATTCAAATGTGAGGAGTGTGGGAAGCTGTTTAAGCGACAGCTCTACCTCAAGGAACATGTGGCCGCACTGCACACGCGTAAGCCGCTTTACTCGTGTGAGGTTTGTGGTGCGACATTCAACTCTAATGCGAACAAGTATTCTCACCGCAAAAATAAGCACCCACTGGAGTGGGAGGCACGCCGGAAACAACTGGAAGAACAACAACAGCAACAACAAAGGCCCCAGTAG
- Protein Sequence
- MDEKCRLCLSQFENLQASATTIEEDKFREKLKTVFTFPITAIESFPSTVCQQCEEQVSVFHSYHELVKTNQEQLWALQHQKYIEMVKSEPSLHDDYDSFEDKSVETGLCKVEIVDVDEGAQPARVGQKRRGRPRKGEVRESKQSKSPPKRKYKSMDETNQRLREFYDMKCELCDEKLDSFTALKNHYYKQHQVQGYIKCCERTFHSRYRLLEHLSKHVGASMVRCEICDKNFSSRSYLLVHNSRMHGQAEDRPYKCTQCHQSYAMECHLKAHVVSHVRVNCTVCGKELASSLSLRTHMINMHGNRENHICDTCGREFRSRQAFERHVKLHLGLEVTEQVQCTVCSKWLNSKRALKMHVKLVHMEAGQTFQCDLCSQQCPNSRALASHKQRVHVEERFKCEECGKLFKRQLYLKEHVAALHTRKPLYSCEVCGATFNSNANKYSHRKNKHPLEWEARRKQLEEQQQQQQRPQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00099219;
- 90% Identity
- -
- 80% Identity
- -