Basic Information

Insect: Anopheles farauti
Gene Symbol: grau
Assembly: GCA_000473445.2
Location: KI915075.1:176373-179051[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 1.9 1.1e+02 3.1 0.2 9 23 237 252 235 252 0.85

2 14 0.021 1.3 9.2 1.7 6 23 261 278 261 278 0.99

3 14 0.041 2.4 8.3 1.0 1 23 284 307 284 307 0.87

4 14 3.8e-05 0.0023 17.9 0.9 1 23 315 337 315 337 0.96

5 14 0.0016 0.095 12.8 0.6 2 23 346 367 345 368 0.94

6 14 1.5 90 3.4 0.1 2 21 425 444 424 447 0.87

7 14 8.2 4.9e+02 1.1 2.6 6 23 457 474 452 474 0.89

8 14 1.2e-05 0.00072 19.4 1.2 1 23 480 503 480 503 0.96

9 14 0.011 0.65 10.1 0.5 6 23 513 531 513 531 0.98

10 14 0.002 0.12 12.5 0.1 2 23 538 559 537 559 0.96

11 14 1.4 80 3.5 8.2 1 23 569 592 569 592 0.96

12 14 0.00045 0.027 14.5 1.6 2 23 599 620 598 621 0.94

13 14 0.00014 0.0084 16.1 3.5 1 23 627 649 627 649 0.97

14 14 0.019 1.1 9.4 1.4 1 23 655 678 655 678 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	1.9	1.1e+02	3.1	0.2	9	23	237	252	235	252	0.85
2	14	0.021	1.3	9.2	1.7	6	23	261	278	261	278	0.99
3	14	0.041	2.4	8.3	1.0	1	23	284	307	284	307	0.87
4	14	3.8e-05	0.0023	17.9	0.9	1	23	315	337	315	337	0.96
5	14	0.0016	0.095	12.8	0.6	2	23	346	367	345	368	0.94
6	14	1.5	90	3.4	0.1	2	21	425	444	424	447	0.87
7	14	8.2	4.9e+02	1.1	2.6	6	23	457	474	452	474	0.89
8	14	1.2e-05	0.00072	19.4	1.2	1	23	480	503	480	503	0.96
9	14	0.011	0.65	10.1	0.5	6	23	513	531	513	531	0.98
10	14	0.002	0.12	12.5	0.1	2	23	538	559	537	559	0.96
11	14	1.4	80	3.5	8.2	1	23	569	592	569	592	0.96
12	14	0.00045	0.027	14.5	1.6	2	23	599	620	598	621	0.94
13	14	0.00014	0.0084	16.1	3.5	1	23	627	649	627	649	0.97
14	14	0.019	1.1	9.4	1.4	1	23	655	678	655	678	0.91

Sequence Information

Coding Sequence: ATGGAGGAGTATAATGAATTAAAACAACCGGCTTGCAACGAGCTTTGCTTGCTGTGTCTGCTGGAAAGCAGCGATCGACATTCCCTCGCCGAGAAGACAAACGTCTGCAATGGTTCAATCCAGGACGTACTATTTAAACACTTTTGGTTCGCGGAAGCTGCCTACGAGGGACGCTACATCTGTTCCGCTTGCTGGGACATGCTATATCCGTTTCACAAATTTTACATCGAAATCGAACGTTTGCACGCTACAAAACTACCGGCCACGATCAAGCGCGAACAACATTCCACCGGGCAGGATGAGGAGCTTGCAGTTACACTTAGCGATGGTACTGAACAACTCGAGCTCCTGCAAGATGCTAACGGTTTTATAACGAGCCTGAACGAAGTGTTCGTGAAGGAATGCTTCTCCGACAGTGAGGACGATGGACACGCTGAGACGATCGATTGCGAATCGGACGATGACGAGGGTGACACCGGGTCGGATGCTGACTCGGACGTTCCATTATCGGAGCTGAGGAAAGCGACAACGGACGATGGTCAAGAACGCAGCACCCGCAAAGGCACCTCGGCACTGTTCGACGGTATCGGCCTTTCGCTGTGCAGAATAATCGAAAACAAGCTCCAGATCGTGTGCCATGAATGCTTTCTTCAGTCGAAGAAATCGGCCGACAAGGCTGTCGATATCGACGAGCTGCTGCGGGACGCTACCTACTTCACGTTCGCCCAGCTGATGAAACACTATCGCCGGGAGCACAAAACGGCTGGGTATGCGGTGTGCTGCAGTCGGAAGTATTCGCGCCGTCGCACGCTCAAGATACACGTGCGGTCGCACGGCAAGCGTGTCGTGCATCGGTGCCTGCCGTGTGGGATTAAGTTCCGGAAGCAGGAGTCGTTGAACGATCATAATCTGCTGATGCACACGGCGGAGGAAGCGAAGCAGTACAGGTGTGATAAGTGTACCAAGGCGTTCGCAACGGAAGACTTGCTCAATTCGCACCATGCGTGGCATGAGAATGTCGAGCGAAAGAAAATCGTCTGCAACGTGTGTAACGTATTCTTCGCCAGCTTCCCTTCGCTCGAGAAGCATCGAATGCTTCATCACCCCGAACCGGACGGGACGGAAGGAACGGTGCAGTCGTTATCGACCCCCGTGCCAAACGGTACCTCGGATCCAACGGACGACAAACTAACCGAATCGCACTACCGAACGCGCGTCTCCGCTGAGGAGATCAGCGCCCAGGACGAGTTCATCAAGCGCTACTGTGTGCTGAGCTGCACGCAGTGCGAGTACATCGCCGACACGTTCGCCCAGCTGCGGCAACATGGGACGGAAGCGCACGAGCTGCGCGCCTGCGAGGTGTTTTGCTGCGATCGCACCTACAGCAAGCGCCAGTCGCTGTACGATCACTGTCTCGTGCACGAAAACCCGGACTGCTTCCGGTGCAGCGTGTGCGGCAAGCAGTACTCGAGCAGCCGGAGCCTCCAGGCGCACAAAACGCGCATCCACACGCCCGCCGCCGAGCGTCCGTTCTGCTGCGAGCGGTCGTTCACGACGGCCCGGGTGCTGAAAAGCCACCAGCAGACGTACCACGGCGCGAGCTTCAGCTGGATCTGCGACGTGTGCGCGAAGGGCTTCAACAGCCGGCCGCTCTTCGAGAACCATCGGCTAACGCACTCGGTCGAGGGCAAAACGCAGCTCAAGCACCAGTGCGAGGAGTGCCACAAGTGGTTGCGCAACAAAAAGTCCTACCAGCAGCACCGGATCCGCTGCCACGCCAACAACGGCCCGGTGAAGTGCCAGTTCTGCGGCAAGGAGTCGGTAAACGCGAGCGCCCTGCAATCGCATATCCACCTGCACCATGCCGAGCGGCCGGAATATCCCTGCAAGCACTGCAAGAAAAGCTTCAAGACGTCGTTGCGCTTGCGCGAGCATGAGGCGACGCACACCGGCACCGTCCTCTACCGCTGCCCGTGGTGTCCGCGCACGTTCGCGTGCGGTTCCAACATGTACAAGCACAAGAAGGCGGGCCACCCGGTCGAGTGGGCCGCCTCGGTCAACAAGCGGTTCGGGGAGCGATGA
Protein Sequence: MEEYNELKQPACNELCLLCLLESSDRHSLAEKTNVCNGSIQDVLFKHFWFAEAAYEGRYICSACWDMLYPFHKFYIEIERLHATKLPATIKREQHSTGQDEELAVTLSDGTEQLELLQDANGFITSLNEVFVKECFSDSEDDGHAETIDCESDDDEGDTGSDADSDVPLSELRKATTDDGQERSTRKGTSALFDGIGLSLCRIIENKLQIVCHECFLQSKKSADKAVDIDELLRDATYFTFAQLMKHYRREHKTAGYAVCCSRKYSRRRTLKIHVRSHGKRVVHRCLPCGIKFRKQESLNDHNLLMHTAEEAKQYRCDKCTKAFATEDLLNSHHAWHENVERKKIVCNVCNVFFASFPSLEKHRMLHHPEPDGTEGTVQSLSTPVPNGTSDPTDDKLTESHYRTRVSAEEISAQDEFIKRYCVLSCTQCEYIADTFAQLRQHGTEAHELRACEVFCCDRTYSKRQSLYDHCLVHENPDCFRCSVCGKQYSSSRSLQAHKTRIHTPAAERPFCCERSFTTARVLKSHQQTYHGASFSWICDVCAKGFNSRPLFENHRLTHSVEGKTQLKHQCEECHKWLRNKKSYQQHRIRCHANNGPVKCQFCGKESVNASALQSHIHLHHAERPEYPCKHCKKSFKTSLRLREHEATHTGTVLYRCPWCPRTFACGSNMYKHKKAGHPVEWAASVNKRFGER

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00106587;
90% Identity: -
80% Identity: -