Basic Information

Insect: Anopheles farauti
Gene Symbol: -
Assembly: GCA_000473445.2
Location: KI915043.1:11951768-11954066[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 2 1.2e+02 3.0 1.4 2 23 207 229 207 229 0.93

2 12 0.00049 0.029 14.4 0.2 1 19 239 257 239 260 0.95

3 12 0.00072 0.042 13.9 3.3 1 23 267 290 267 290 0.93

4 12 0.16 9.2 6.5 0.3 2 19 380 397 379 399 0.82

5 12 0.00094 0.055 13.5 3.1 1 22 408 429 408 433 0.94

6 12 0.17 10 6.4 0.1 2 20 493 511 492 513 0.92

7 12 3.2e-05 0.0019 18.1 2.2 1 23 520 543 520 543 0.96

8 12 3.1e-05 0.0018 18.1 0.9 3 23 552 572 550 572 0.98

9 12 0.006 0.35 11.0 0.1 2 23 579 603 578 603 0.93

10 12 1.7e-05 0.001 19.0 2.3 1 23 609 631 609 631 0.98

11 12 0.47 28 5.0 2.3 1 23 637 662 637 662 0.94

12 12 0.01 0.6 10.2 0.4 1 23 668 691 668 691 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	2	1.2e+02	3.0	1.4	2	23	207	229	207	229	0.93
2	12	0.00049	0.029	14.4	0.2	1	19	239	257	239	260	0.95
3	12	0.00072	0.042	13.9	3.3	1	23	267	290	267	290	0.93
4	12	0.16	9.2	6.5	0.3	2	19	380	397	379	399	0.82
5	12	0.00094	0.055	13.5	3.1	1	22	408	429	408	433	0.94
6	12	0.17	10	6.4	0.1	2	20	493	511	492	513	0.92
7	12	3.2e-05	0.0019	18.1	2.2	1	23	520	543	520	543	0.96
8	12	3.1e-05	0.0018	18.1	0.9	3	23	552	572	550	572	0.98
9	12	0.006	0.35	11.0	0.1	2	23	579	603	578	603	0.93
10	12	1.7e-05	0.001	19.0	2.3	1	23	609	631	609	631	0.98
11	12	0.47	28	5.0	2.3	1	23	637	662	637	662	0.94
12	12	0.01	0.6	10.2	0.4	1	23	668	691	668	691	0.96

Sequence Information

Coding Sequence: ATGGCCCCTACAAAACCGAGCTTAGCGGATCCTAGTTTTCGAACCGTACATTGCCGAGTGTGCTGCAAAGCGCTTCGAAGAGCAAAGGCCCTGAACATATTCTGGTCTATGGATGAAACCAAAGCCAGCGAAGCCTCCAGAACCATCGCGGAGTTGATGGCAGAGTTTGCTGATGTTACCATAAACAACAACAACGATCGTTCGAAATACATATGTCCAGCTTGCTTTAAAGTGCTCGACAAAGGCATCCAACTGAAGCTGCAAATCCGCGCCGCGGAGAAAGTTGTGTCTACGAAGCTGCAATCGATCGAGATAGAAAACGTCTGCGAACAGGATTACGATTTCGAATACCTTGAAGAGTTCAAAGACGAGATTTCGTTGGAAATTATGCCCCAGCGTGAAAGACTTCTTTCGGTGTGCGACTCACCCGGGACGGATGAAGGTGAAGATGAGTTGCTGGCGAAGCAGCTAAACTCTCAGCTTGCCGAAGAAGAAATTGATTCGCTCGAGGATGGATTGCGCGAGCAGGGAAAGTTCGCATTCGTAATGCCCGCCGCTGAGCTCATTGCGAATCGCATTGAGTTTGACGATTTTGAATACCTGGAAATACGAGGCGAACGTTGCTGCGGCTGTGCACACATCGCAACGTCCCGCGACGAGTTGATGGCGCACGCGAAAGAAAAACACTCGCAAAACTACTACGCCGACAGTAGCTACACGTGTCCGACATGCTATCAGAAATTTCCGACGGCGGATGCGCTGGAAAAGCACAACCAATACTATCTGTATAGCGACGTGTTCTTGTGCACCATTTGCCAGGAAGCGTTCAATTTCCAGAGCCACTTGATGCTACACTTGAAGGCATGCCATGGTCACGTTTCGCACGACGATGAAGCACCGGAAGTGGACGATGAAACACCCAAACGAAGGAATCCATGGAAAGCGAGTGCCGTGGAGATCTTTCTGCCGGATGTTCAATTCATAAAAGAAACAAGAGAACTTCCACTGTATCGACAGTACACGATCTCAGGTGAACGTTGCTGCGTCTGTAGGCTATACCCAACGACGCTAGAGACACACGCGGCTGAAAAACATCTCGATCTTGAGGAAGTACTAGAACCGTGTCCGGACGAGCTGCGGTGCAACGTTTGCAAGCGAATGTTCAATTCCACGCATGATCGCGTGTTGCACGAAGAGGAACGAAGGGATCTGAAGCAAATCTATCAATGCAAGCTGTGCAATGTGCTGTTCACACGCAAGCATCTGCTTGTGAAACATTTCAGGACTGCAAAGAATCATAGAAATCGGCGTGTGGCACATGTGGAGAATGATGGTCCATCCGACTCGCAAGAAAACACGGAAGAGTATGTCAGCGAGAAGGAGCTGCTCCAGCACGCTCGCCAAGTGCACGATGGGCGTAGGAAGGAAAACGAAAGCAAACTCACTCAACACGGCTCGACGCCGAACGAATCGCTCATTTGCCCCATCTGCCGGCGGTTGTTCGAATCGCGCGAGAAGGTAAGCAAACACCGTGCCTACAAACTTGCCCTCTCGAAACACACCTGCCGCCAGTGTGGGCGCGTATTCATGAAAGCTTCCAGTCTCCGGCAGCACCAGCTTCGCGAACATTTGAATCTCGTACCGGAGTTTGGATGCGAAGTGTGCGGTAAACACTTTGCAGCCCGTTCGACGCTAGTCAAACACCGGCGGGTGCATGAACCGTCGAAAAACTTGCCCTGCACGTTTGCCGGCTGTGAGGCACGGTTTCGCGACGATGCACTGCTGCGGCGACACTACCGGAACGTGCACACGGAGCTAAAGGCGTACGCGTGCGCCCACTGCCAGAAGGAATTCCGCACGAAGGAATCGCTTGATATGCATCAGCGCAGTCATACGGGTGAGCGACCGTTCGTGTGCCGGTACGAGGGTTGCAGCAAACGATACGCTCATGGAACGGACCGGAAGCGGCACGAACGATCCTCTCACACGGGCGAAAGGCCACATACGTGTCCGGTGTGTGGGGGCGGGTTTCTGCGCAAGCGAGAGATGCGACTGCATATGGAGAAAGTTCACTGA
Protein Sequence: MAPTKPSLADPSFRTVHCRVCCKALRRAKALNIFWSMDETKASEASRTIAELMAEFADVTINNNNDRSKYICPACFKVLDKGIQLKLQIRAAEKVVSTKLQSIEIENVCEQDYDFEYLEEFKDEISLEIMPQRERLLSVCDSPGTDEGEDELLAKQLNSQLAEEEIDSLEDGLREQGKFAFVMPAAELIANRIEFDDFEYLEIRGERCCGCAHIATSRDELMAHAKEKHSQNYYADSSYTCPTCYQKFPTADALEKHNQYYLYSDVFLCTICQEAFNFQSHLMLHLKACHGHVSHDDEAPEVDDETPKRRNPWKASAVEIFLPDVQFIKETRELPLYRQYTISGERCCVCRLYPTTLETHAAEKHLDLEEVLEPCPDELRCNVCKRMFNSTHDRVLHEEERRDLKQIYQCKLCNVLFTRKHLLVKHFRTAKNHRNRRVAHVENDGPSDSQENTEEYVSEKELLQHARQVHDGRRKENESKLTQHGSTPNESLICPICRRLFESREKVSKHRAYKLALSKHTCRQCGRVFMKASSLRQHQLREHLNLVPEFGCEVCGKHFAARSTLVKHRRVHEPSKNLPCTFAGCEARFRDDALLRRHYRNVHTELKAYACAHCQKEFRTKESLDMHQRSHTGERPFVCRYEGCSKRYAHGTDRKRHERSSHTGERPHTCPVCGGGFLRKREMRLHMEKVH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00103304;
90% Identity: iTF_00103304;
80% Identity: -