Basic Information

Insect: Anopheles farauti
Gene Symbol: zfh1
Assembly: GCA_000473445.2
Location: KI915047.1:1856793-1869432[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.23 13 6.0 2.1 2 23 53 74 52 75 0.94

2 9 0.00064 0.038 14.0 1.1 1 23 237 259 237 259 0.95

3 9 8.6e-05 0.0051 16.8 1.5 2 23 266 287 266 287 0.97

4 9 2.4e-06 0.00014 21.6 5.8 1 23 296 318 296 318 0.99

5 9 1.3e-05 0.00076 19.4 0.8 1 21 324 344 324 345 0.95

6 9 0.88 52 4.1 0.1 2 21 656 675 655 676 0.91

7 9 1.6e-05 0.00097 19.0 4.0 1 23 1054 1076 1054 1076 0.95

8 9 8.4e-05 0.005 16.8 7.8 1 23 1082 1104 1082 1104 0.98

9 9 0.045 2.7 8.2 7.0 1 21 1110 1130 1110 1131 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.23	13	6.0	2.1	2	23	53	74	52	75	0.94
2	9	0.00064	0.038	14.0	1.1	1	23	237	259	237	259	0.95
3	9	8.6e-05	0.0051	16.8	1.5	2	23	266	287	266	287	0.97
4	9	2.4e-06	0.00014	21.6	5.8	1	23	296	318	296	318	0.99
5	9	1.3e-05	0.00076	19.4	0.8	1	21	324	344	324	345	0.95
6	9	0.88	52	4.1	0.1	2	21	656	675	655	676	0.91
7	9	1.6e-05	0.00097	19.0	4.0	1	23	1054	1076	1054	1076	0.95
8	9	8.4e-05	0.005	16.8	7.8	1	23	1082	1104	1082	1104	0.98
9	9	0.045	2.7	8.2	7.0	1	21	1110	1130	1110	1131	0.96

Sequence Information

Coding Sequence: ATGGTGTCCTGCAGCGTTGCCGTGTCGACGTACTACAACGCGGACGGAAGTATCATGCCATCTTCGACCAAGTTTTCCCTACAGTTTCCTTCCTTGCCATCTGGTCTACCAAAGGACAGTGCGAACGATGCACTAGCGGACGCCGATTGCTGCGTTCAGTGCCCCCAGTGCCACCAGACGGTCCAGGGAGTCGAGGCGCTGAAAGAACACATCCAGCACCATCATAGTGGCAGTTCGGACGGGCTGCGGCTGAAGTTCCCCGAAACCGAACTGGACAACGACAACGACGAAGACGAAGACGACGCGATGGCGGAGGAGGACGAACATCACGTGGACCCGGACGCGGCGTCACCACTTCCGGCCGCACCGCTCGAGTCGCTGGCGGCGATCGGTGGACGGGCGAGCGGTGACCTGATCGGTAGCCGGCTCCAGGCCAAGTGCGTCAGCTTGTTGCAGCTCCAGCAGCAGAAACACCACGCACCCAAGCCGGACCTCGACGAGGACGACGACGAAGACGGTGACGGAGTCGAGGTCGAGGTGGATGTGACGCAGCGGGCGACACCCCGCAACCTACTGCTACCGTCCGGCCTGCAACCGGACCTACCGTACGGGCCGCGATCGATGATGGTCAGCCCGTCGCAGGACGGCAGCAGCAACTCCAGCGGTGGACCGAACCTGCCAATCGGTGGGCTGGTGAAGGACGGTGCGTACGACTGCGCCCAGTGCCCGAGCACGTTCACCAGCCGGGATCAGCTGGAGCGGCACGAACTGCACCACGCACCGTCAGCGGATGCGAGCTGCAAGGTGTGCCACAAGCCGTTCGCGAACGTGTACCGGCTCCAGCGCCACATGATCTCGCACGACGAATCGTTGCAGCGCCGCAAGTTCAAATGCAACGACTGTGATAAAGCGTTCAAGTTCAAGCACCATCTGAAGGAGCACGTCCGCATCCACTCCGGCGAGAAGCCGTTCGTCTGCCCGAACTGCGGCAAGCGCTTCTCGCACTCCGGCTCCTACTCGAGCCACATGACGTCGAAGAACAACGGTATGGCGGGTGCCGCAAACGGAGCCAATGGTGGAGGTCTGATCGGTCGGTCCCCGATCGGCTATCGGCCGGCGATGGACGCGTCCGGTCGGTTAGGCCTGGTGACGTCACCCTCGCCGACGTCCTCCTCGTGCTCGTCGGCGACGAAGCACGAGCTGGAGGGTGGTGTGGTGGCGACCACAGGACCACAGGCCGGCGATATGGAAGCGTTGCTGCTGAGCAAACTGCACCATGCCTCCTGGTTCTACTCGCTCGCACTGCTCGAACCGAACATGCTGCGCCTGATGGAGCTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGCGTGCGAACGAACGACCTCAGTCCGGTGGTGACGACCCGCAACGGCCCGCCTCGACCAAGCGTCCGGCATCGTCCACCGAAGCGCCCGAATCCGAGCATCCACCACGGCAGCTGGCCGTGGAGTGTCCGGAGCGTATGGAGATCGATGAGGAGCAGGAGGGTTACGCCGAGGCGAAGGTGGAGGTCGTAATGGCGACCGACGACAGTAGCGATCCGGGTGCCGGTGGCGAGGAGAAGCAGGAAGGGGTGGCGGAAGTGGCCACCCCGCACGCTGCACCACCCCCAGCGAAGGTCGAGCCGGAGATGGACCAGCTCGTCCGGACCAAGCAGGAACCACCGGAGGAGGACGATAACGAGCATAGCATTCCGCCCAGCCTGTCGGACGCCGGCCGATCTCCGTCGCTGGACGTCCCGGTGAAGGACGAACCGCCGGAGGAGCCCGGCCCGATCGAGATGGCCGAGCTGAAGCTGACCGATCCGGTCGACGAGCACGCCGGTCGGTTTCGGTCGCCATCTGCGACGTCCCTGTCGCCTTCGGTGTCGTCCGTGCACTCGCCGCTTCACTGTCTGTACTGCAGCGAGGAGTTCGCGTCCGAGCCGGAGATGCTCCAGCACGCGCGCATGTTCTGCAAGCGTCCGGGAGGTCCTGGGGGTCCGGGAGGTCCGGGCGGTGCTGGTGGTGATCGTGGCACCGGTGCCGGTTCCGGTCAAGCGGGTCTCGGTGGTATGCCACACGGCGGGGGTGGTGGGAAGGTGCGCGTACGCACCTCCATCTCCGAGGAGCAGCAGAACGAGCTGAAGAAGTACTACGCGCGCAACAGCAAACCGAGCCGCGACGAGTTCCAGGCGATCGCCCACCACGTCAAGATGGAGGCGCGCGTCGTGCAGGTCTGGTTCCAGAACAATCGGTCGCGCGAGCGCAAGATGGGCGGCGTGCTGCGTCAGTACCCGAACCCGGGTGCACCGAGCCAGACGACGCCCTCGTCGCCGCTCCACGCCGACCGCGCACCATCGGTCGTGACCGGGCAGAGCGACACCGGCGACCAACCGCTGGACCTCTCCGTGAAGAAGGGCCTGCTGACGGAGGCACTGCTGACGGCGGCGACCAACTCGCAGGCAGCCGCCACGGCAATGGCCGCCGGTGCCCTGCCGGCGGTGCTCCTCCAAGCCGACACCATGTCCGCGCTCAACGAAGCGATGAACCTCAGCATCAAAACGTCCCCGAGCGCGTTCTTCTACCACGACATACACCCGATCCACGGTGTGACGCCCCCGCAGGCCGCGCTCAAGCTCGCACGCGAAACACCGTCGCCGCTGCGCGACGTCAGCCGCAGCCAGCCGCTGCCGGTGCATCCAGCGCACCAGCCGCCAGCCCAGCCGCAGCACACCTTCGGCAAGTACCCGGCCGTGCACCATCACCCACACCCAGCCAACCTCGCCACCATGGACCACCTGTTCCGGCAGTTCTCGCCCGAGCTGTCCGCAGCGGCGGCAGCGGCCGCCGCAGCCGCCGCCAGCCTCAGCCCCGGTGGCGACGGTGGCGACCCCACCGCCAACAAGTACTACGGCGCCTTCCCGACCGACAAGCAGCTGCTGCACTCGATGCTGAACGTGCCGAAGCGCAATGGGGGCGGTGGTGGAGGGGGCGGCGCGGCCGGTGGTGGTGCCTACGGTGGCACCGCAGCCGCCGCCAACGTCGGCAAGGACCCGGCCGGCCAGCTGGCGGCACATCCGACGCCGGACGCCGAGGGTCAGTACGTCTGTGATCAATGCGACAAAACTTTCAGCAAGCACAGCTCCCTCCAGCGCCACAAGTACGAACACTCCGGCCAGCGACCGTACAAGTGTATGGAGTGTCCGAAGGCGTTCAAGCACAAGCATCACCTCACCGAGCACAAGCGGCTGCACAGTGGCGAGAAGCCGTTCCAGTGCTGCAAGTGTCTGAAGCGGTTCTCGCACTCCGGCTCGTACAGCCAGCACATGAACCATCGCTACTCGTACTGCAAGCCGTACAGGGAGGGCAAATAA
Protein Sequence: MVSCSVAVSTYYNADGSIMPSSTKFSLQFPSLPSGLPKDSANDALADADCCVQCPQCHQTVQGVEALKEHIQHHHSGSSDGLRLKFPETELDNDNDEDEDDAMAEEDEHHVDPDAASPLPAAPLESLAAIGGRASGDLIGSRLQAKCVSLLQLQQQKHHAPKPDLDEDDDEDGDGVEVEVDVTQRATPRNLLLPSGLQPDLPYGPRSMMVSPSQDGSSNSSGGPNLPIGGLVKDGAYDCAQCPSTFTSRDQLERHELHHAPSADASCKVCHKPFANVYRLQRHMISHDESLQRRKFKCNDCDKAFKFKHHLKEHVRIHSGEKPFVCPNCGKRFSHSGSYSSHMTSKNNGMAGAANGANGGGLIGRSPIGYRPAMDASGRLGLVTSPSPTSSSCSSATKHELEGGVVATTGPQAGDMEALLLSKLHHASWFYSLALLEPNMLRLMELXXXXXXXXXXXXXXXXXXXXXXRANERPQSGGDDPQRPASTKRPASSTEAPESEHPPRQLAVECPERMEIDEEQEGYAEAKVEVVMATDDSSDPGAGGEEKQEGVAEVATPHAAPPPAKVEPEMDQLVRTKQEPPEEDDNEHSIPPSLSDAGRSPSLDVPVKDEPPEEPGPIEMAELKLTDPVDEHAGRFRSPSATSLSPSVSSVHSPLHCLYCSEEFASEPEMLQHARMFCKRPGGPGGPGGPGGAGGDRGTGAGSGQAGLGGMPHGGGGGKVRVRTSISEEQQNELKKYYARNSKPSRDEFQAIAHHVKMEARVVQVWFQNNRSRERKMGGVLRQYPNPGAPSQTTPSSPLHADRAPSVVTGQSDTGDQPLDLSVKKGLLTEALLTAATNSQAAATAMAAGALPAVLLQADTMSALNEAMNLSIKTSPSAFFYHDIHPIHGVTPPQAALKLARETPSPLRDVSRSQPLPVHPAHQPPAQPQHTFGKYPAVHHHPHPANLATMDHLFRQFSPELSAAAAAAAAAAASLSPGGDGGDPTANKYYGAFPTDKQLLHSMLNVPKRNGGGGGGGGAAGGGAYGGTAAAANVGKDPAGQLAAHPTPDAEGQYVCDQCDKTFSKHSSLQRHKYEHSGQRPYKCMECPKAFKHKHHLTEHKRLHSGEKPFQCCKCLKRFSHSGSYSQHMNHRYSYCKPYREGK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00100201;
90% Identity: iTF_00100201;
80% Identity: iTF_00100201;