Afar000632.1
Basic Information
- Insect
- Anopheles farauti
- Gene Symbol
- -
- Assembly
- GCA_000473445.2
- Location
- KI915044.1:7286073-7288195[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.0017 0.098 12.7 6.1 2 23 83 105 79 105 0.92 2 10 5.9e-05 0.0035 17.3 0.6 1 23 108 130 108 130 0.98 3 10 0.0015 0.087 12.9 1.0 1 23 136 159 136 159 0.98 4 10 4.7e-06 0.00028 20.7 0.5 2 23 166 187 165 187 0.97 5 10 0.00012 0.007 16.3 6.6 1 23 193 216 193 216 0.96 6 10 1.4e-05 0.00083 19.2 3.0 1 23 221 244 221 244 0.96 7 10 0.0072 0.43 10.7 1.2 1 23 250 272 250 272 0.97 8 10 0.16 9.3 6.5 0.1 2 21 279 298 278 299 0.93 9 10 8.8 5.2e+02 1.0 1.5 6 23 308 326 308 326 0.89 10 10 0.0024 0.14 12.2 1.3 2 22 354 374 354 374 0.94
Sequence Information
- Coding Sequence
- ATGAAAGTTTACCGATTAGAGCACTTCCCCAAGGTGTGTCGGATTTGCTTGCAGCATCAACCGGAATACGCGATGAGTTCTCTTGATATATTTGCTCTAGCTTATAATATACCACTTTCCGATGTTGTAGATGAGCTAATAGAATCCGCTTCACCGGATTTGCATCATCATACGGCGACTGCAATTTGTAAAGTATGCTGCGGCGAATTGAACTCATTTCTCGGAAACATTTCCTACAAATGCCAACAGTGCAGTCGGTGCAACCTCGAGTTTGCCAACAAACGAGAGCTGTTGCGGCACAGACGGTCCTGCCATCGTGATTACATGTGTGACATGTGCGGGCTTGCCTTCGACACGAAGTTTGTGCTGGAAACACATCGGAAACGGCACGCAACGGTACGCCAGTACAAATGTGAGTACTGCCCACTGGATTACCACACAAAGGCGGAAATGCTGCTGCATGTACGGAGGCTGCATCTGAAAGCTTTCGTGGTGTCTTGCCCGAAGTGTGCGCTAACGTTCTCCACGAAACAATTGCTGGCGCAACACATGAAGACGCACACAAACCAACGTTCACACACATGCAATATCTGCGGCTTTACCTTCAACGCCCACACGCACCTGAATCGGCACATGAAGGAACGGCATCAAGGGGTGCAATATCAGTGCGACCACTGCGACTTGTCGTACCGGCGCAAGGATAAGCTGCGCATGCACGTCGAGAAAACGCACAACATTCAAACATACTTTGTATGTGACATATGTCTACAATCGTACGATACGGATGAAAAGTTAAAAGAACATCAGAGCCATCATTTATACCCAACAGATTTACAGTGCGGCATATGTCTGGGAGCGTACAGGACTGAGGATGAATTTAATCAACATCTGTGCATAACGTACCGTGAAAACTACATCTGTTGTGAGCGAGACTACAAGTACCATTTCTTCTATAACAAGCACATGTTCCTGGTACACGGTAAGCAGACGAATGTACGCGTCAAACCCGTCGACGGGTTGCTGGTGGGTCAATATCGTGCGACACGCAAGCAAGCTGAACGTTGTCCAAAGTGTGAACAAGAATTTCCTACTCGACATCAAAAGAAACAGCACATGGAAACATGTGGCACGATGCAGTCCAAACTGTTTGATCGAGACGGTGCGGGCCTTTCTTCATAA
- Protein Sequence
- MKVYRLEHFPKVCRICLQHQPEYAMSSLDIFALAYNIPLSDVVDELIESASPDLHHHTATAICKVCCGELNSFLGNISYKCQQCSRCNLEFANKRELLRHRRSCHRDYMCDMCGLAFDTKFVLETHRKRHATVRQYKCEYCPLDYHTKAEMLLHVRRLHLKAFVVSCPKCALTFSTKQLLAQHMKTHTNQRSHTCNICGFTFNAHTHLNRHMKERHQGVQYQCDHCDLSYRRKDKLRMHVEKTHNIQTYFVCDICLQSYDTDEKLKEHQSHHLYPTDLQCGICLGAYRTEDEFNQHLCITYRENYICCERDYKYHFFYNKHMFLVHGKQTNVRVKPVDGLLVGQYRATRKQAERCPKCEQEFPTRHQKKQHMETCGTMQSKLFDRDGAGLSS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -