Afar001145.1
Basic Information
- Insect
- Anopheles farauti
- Gene Symbol
- -
- Assembly
- GCA_000473445.2
- Location
- KI915060.1:308660-310172[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 7 0.82 48 4.2 0.0 3 12 212 221 211 230 0.88 2 7 0.0006 0.035 14.1 0.3 1 23 236 259 236 259 0.93 3 7 2.2e-05 0.0013 18.6 1.6 2 23 266 288 265 288 0.96 4 7 9.4e-06 0.00055 19.8 1.0 1 23 294 317 294 317 0.96 5 7 5.4e-08 3.2e-06 26.8 0.1 2 23 324 345 323 345 0.97 6 7 0.00034 0.02 14.9 1.9 1 23 351 373 351 373 0.97 7 7 9.6e-05 0.0056 16.6 1.9 1 23 378 401 378 401 0.98
Sequence Information
- Coding Sequence
- ATGGCAAACGGAACACAGAAAATGATCGTTATATGTCGATTATGTTTATCCCAGGACGAAAGGCTGCTCAGACCAGTCACCGAGACTATCGATGCCTCGTTGACCATCCTTGAGATAAAACGTTTCAGTGGCATTCCGATAAATATAAACGAAGAGATCGCATATGCGATATGCTTCGAGTGTGCGGATCGAGTTCAAAGCTCAATTGCTTTCCGCAATGCGTGCCTGGATAATGATGGCCTCTTTCAGGAGCTTCGTTCTGCTTTCATGGCCCAGCTGGGATGTACGGAGAAGGATGCGGTCGTTATCGTGGATGACAGCATATCCAATCGTTTAGGGCAGCAATATTTCCAAATCGACGACGATAACAATGTACACATAGAAAACCTTACCACGGATCCTTACAAGGAAGATGTTTCCATCGAACAAGCGGAGGCTGTCATTGTATTCGATCGTGTGGAATCTGACCCGGTGAGTGACGAGTACGATGCGGCTGATAACGTAAGATTGCCGGGGCAAACAACTGAAAGTAGTGATCTGAGCGTCACAACCGAAGAGAGCACTAAACCATCGCATTCGAACCGCGAGATTAGGTCGATGAGAACGGAGAAATCGTCGCGCACGAAGAAACTTTGCACCATTTGCGGAAAAATGGTAACGAGCCTACCGTCCCACATCGCACAGCACACGAACGAGCCAACGCAGCACGCCTGCCCGTACTGTCCGGTGAAGATGACGGTCAAGAGCAACCTGAAGCAGCACATCCAAGCCGTGCATCTAAAAAAAATCAGTAAAAAATGCAAACTGTGCGATAAAGGCTTCACTCAGAACAAATCATATGCCTCACACATGATTTCGTTCCACGGAATCGGTAGAAAACATCCGTGCAAGCTTTGCTCGAGGGTTTTTAATTTTCCGTCCGGCTTGAAGGATCACATGAATCGAGTACACAGCGAGGTTCGTAGTTTGGAGTGTGACATTTGCGGCAAAATGTTCAAAGTGAAATCCGCGCTAGCAACGCACATTCGTACGCACTCCGGGGATCAACCATACGCGTGCACCCAGTGTCCGAAGCGCTTCAAATCTCAGTTCGCGAAGAAAACACACGAACTAACGCACAGTGGCATCGTTTTCGAGTGTGGATTCTGTAGTAAGACGTACAGATACAAGGCGCTGCTTAGCATGCACCTAAGAAAAACGCATTCGACGGAGATGCTCGAGAGCACAGAGTACGATGAAGAGCAGGAAGTAGACGCTAGTAAGGAAGAAACGTGA
- Protein Sequence
- MANGTQKMIVICRLCLSQDERLLRPVTETIDASLTILEIKRFSGIPININEEIAYAICFECADRVQSSIAFRNACLDNDGLFQELRSAFMAQLGCTEKDAVVIVDDSISNRLGQQYFQIDDDNNVHIENLTTDPYKEDVSIEQAEAVIVFDRVESDPVSDEYDAADNVRLPGQTTESSDLSVTTEESTKPSHSNREIRSMRTEKSSRTKKLCTICGKMVTSLPSHIAQHTNEPTQHACPYCPVKMTVKSNLKQHIQAVHLKKISKKCKLCDKGFTQNKSYASHMISFHGIGRKHPCKLCSRVFNFPSGLKDHMNRVHSEVRSLECDICGKMFKVKSALATHIRTHSGDQPYACTQCPKRFKSQFAKKTHELTHSGIVFECGFCSKTYRYKALLSMHLRKTHSTEMLESTEYDEEQEVDASKEET
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00103170;
- 90% Identity
- iTF_00103170;
- 80% Identity
- -