Basic Information

Insect: Anopheles farauti
Gene Symbol: -
Assembly: GCA_000473445.2
Location: KI915045.1:5550437-5552450[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 7.4 4.4e+02 1.2 0.0 9 23 291 306 281 306 0.85

2 9 0.042 2.5 8.3 3.6 2 20 312 330 312 333 0.93

3 9 8e-05 0.0047 16.9 3.8 1 23 339 361 339 361 0.97

4 9 2.3e-07 1.4e-05 24.8 1.2 1 23 367 389 367 389 0.95

5 9 7.1e-05 0.0042 17.0 1.5 3 23 397 417 395 417 0.97

6 9 0.00045 0.027 14.5 1.3 1 23 423 445 423 445 0.98

7 9 0.00016 0.0096 15.9 1.2 3 23 453 473 451 473 0.98

8 9 7.5e-07 4.4e-05 23.2 2.0 1 23 479 501 479 501 0.99

9 9 0.00055 0.032 14.2 0.7 1 21 507 527 507 528 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	7.4	4.4e+02	1.2	0.0	9	23	291	306	281	306	0.85
2	9	0.042	2.5	8.3	3.6	2	20	312	330	312	333	0.93
3	9	8e-05	0.0047	16.9	3.8	1	23	339	361	339	361	0.97
4	9	2.3e-07	1.4e-05	24.8	1.2	1	23	367	389	367	389	0.95
5	9	7.1e-05	0.0042	17.0	1.5	3	23	397	417	395	417	0.97
6	9	0.00045	0.027	14.5	1.3	1	23	423	445	423	445	0.98
7	9	0.00016	0.0096	15.9	1.2	3	23	453	473	451	473	0.98
8	9	7.5e-07	4.4e-05	23.2	2.0	1	23	479	501	479	501	0.99
9	9	0.00055	0.032	14.2	0.7	1	21	507	527	507	528	0.95

Sequence Information

Coding Sequence: ATGGAAGTGAACGAGGTAGTCGTTCAAACGACAAGTGGAATGTTGGGGTACTGTCGTATCTGTGCGGTAGAAACAATACTCGAGTGTAGCATTGATGAGGTGCTGTACACGGAATCCTCGCTAACGCTGTTCACGATGCTGGAGCGAATGTTTCCCTCCCTTTTCGATCCTGCAGTGCAGCCGGCGGGAAGCGAACACTGGCCAACGAAAGCTTGCCAGGCGTGTAGACACAAAGTGCTGGCCGCCTACGATCTGTACGAGCTATGTCTCGACAGTGTCAATCGGTTGCGCAAGTGTGTCACCGAGCGCTCCGACAGGGAATCGGTCGTGCACACAATCAAAGCGGAACCGGACGGTGCCGGCAGTGTGCCGTACGAGGTAATGATTGAATGCTCGTATGAAGAAGATGATTTTCCACTGCCCGTGGAGGAAGACCGAACGTCGTTGGACGTCGTTGCCGACAGCGAACAGGTAGACGAACAGTCCGTCGATGAAGTTTCCCAAAGACCGACGAGAAAGTGCAGAGGTCGTAAACCGACCGCACCGGAAAAGAAACGCACGAGAATTAAGCGCGAAGTTGTGGAAATCCTGGAAGAGCCCGAGCAAAGTTCTGCCAGCCCGAACGACACAGTAAACGACTCGAATGAGGTCGAAAATCCGTCCACCAAACAGCCGACGGGCAAGAGGCGAGGTCGAAAACCTAAAGCACAAACGGACGACTCTCTGCTCGACGAAACGGATGGTACCATTCGGCAGCGGAAAAGGAAAACGAGAGAGAAACAAACACCGGATGCGGCATCTTCGGATCACATGGAACAGTTGGAGTCAAAGGTCGATGTGTACCAGTGTATACTGTGCGAAGAGGGTCCAACATACAGTTCGCCGCTGGAACTGACCGAACACCTGAAGGCGCTCCATGTGGATCAGATCCGGACATGCGACAAGTGTCCGAAGGTGTTTATGAGCGAACAAGCCTACCAGCACCACCAGTACTGCCACGCCACGTTGCGCGCCTTCTTCTGCACGTTCTGCGACAAGGGTTTCCAAACCGAGCATCTGCTGAAAAGCCACATTCGGTCGCATACGCAGGTGGCCGAGTTTCTGTGCGCACTGTGTGGCAAAAAGTTTAACAACAAGAGCAACCTGCGGCAGCATATGGCACGTCACACCGGCGTTAAACCGTGGGCATGCACACAGTGCCCGAGTCGTTTCTGCACCAAAGGTGCATTAAACTTACATCAGCGTACACATTCAAAATTAAGACCATTTAGTTGCAATAGCTGTCCTTCGCAGTTCTACACGAGATACTCTCTAATCAAACATCAGCTTATTCATACAGGAGAACGTCCTTACGGTTGTGATCTTTGCCCGATGAGATTTGTCTCCACATATCACGTGAAACGACACATGCTGACGCACACGGGCGAAAAACCATTCAAATGTACGTACTGCGAACGCAGTTTCGCCCAGAGCAACGATATGGTGAAGCACATGAAAACGCACGTCGGCGACAATCCTTACCAATGCGATCGATGCAATACGTCCTTCCGGTTGCTCACGGATCTGCGCAACCACTACAACGAAACTTGCCAACCGGTCGAAAAGGGAACTGGCTCGTCGGTGGACGAGGATAAGGGCATTCGCTTCACGAGCTCCTACATTCTGAAGATGCGATATGAGAAGGAAATGGGCCAGTACGAGGGGAGTGAAAATCGGAAAGTTATGACAGAGGCTACAGAGTTCCCCGGTATGATGTGA
Protein Sequence: MEVNEVVVQTTSGMLGYCRICAVETILECSIDEVLYTESSLTLFTMLERMFPSLFDPAVQPAGSEHWPTKACQACRHKVLAAYDLYELCLDSVNRLRKCVTERSDRESVVHTIKAEPDGAGSVPYEVMIECSYEEDDFPLPVEEDRTSLDVVADSEQVDEQSVDEVSQRPTRKCRGRKPTAPEKKRTRIKREVVEILEEPEQSSASPNDTVNDSNEVENPSTKQPTGKRRGRKPKAQTDDSLLDETDGTIRQRKRKTREKQTPDAASSDHMEQLESKVDVYQCILCEEGPTYSSPLELTEHLKALHVDQIRTCDKCPKVFMSEQAYQHHQYCHATLRAFFCTFCDKGFQTEHLLKSHIRSHTQVAEFLCALCGKKFNNKSNLRQHMARHTGVKPWACTQCPSRFCTKGALNLHQRTHSKLRPFSCNSCPSQFYTRYSLIKHQLIHTGERPYGCDLCPMRFVSTYHVKRHMLTHTGEKPFKCTYCERSFAQSNDMVKHMKTHVGDNPYQCDRCNTSFRLLTDLRNHYNETCQPVEKGTGSSVDEDKGIRFTSSYILKMRYEKEMGQYEGSENRKVMTEATEFPGMM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00106540;
90% Identity: iTF_00106540;
80% Identity: -