Basic Information

Insect: Anopheles farauti
Gene Symbol: L
Assembly: GCA_000473445.2
Location: KI915061.1:979831-1002338[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.00036 0.021 14.8 3.6 1 23 34 56 34 56 0.97

2 17 0.53 32 4.8 5.7 1 23 62 84 62 84 0.98

3 17 4.4e-06 0.00026 20.8 3.7 1 23 90 112 90 112 0.99

4 17 1.3e-05 0.00079 19.3 0.3 1 23 118 140 118 140 0.98

5 17 5.8 3.4e+02 1.6 0.1 2 23 233 256 232 256 0.78

6 17 0.072 4.3 7.6 0.3 2 23 310 332 309 332 0.96

7 17 0.19 11 6.3 0.2 1 23 651 673 651 673 0.95

8 17 6.3 3.7e+02 1.4 0.5 1 23 726 748 726 748 0.90

9 17 0.00026 0.015 15.2 0.2 1 23 793 816 793 816 0.93

10 17 0.0012 0.071 13.2 0.8 1 23 823 846 823 846 0.98

11 17 0.0031 0.18 11.9 1.6 1 23 878 900 878 901 0.96

12 17 0.37 22 5.3 0.2 1 23 1204 1228 1204 1228 0.91

13 17 0.00057 0.034 14.2 0.2 2 23 1237 1259 1236 1259 0.96

14 17 0.0089 0.53 10.4 0.1 1 23 1266 1288 1266 1288 0.97

15 17 0.002 0.12 12.5 0.3 1 23 1507 1529 1507 1529 0.96

16 17 0.0072 0.43 10.7 0.0 1 20 1539 1558 1539 1562 0.93

17 17 0.033 1.9 8.6 0.3 1 23 1570 1592 1570 1592 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.00036	0.021	14.8	3.6	1	23	34	56	34	56	0.97
2	17	0.53	32	4.8	5.7	1	23	62	84	62	84	0.98
3	17	4.4e-06	0.00026	20.8	3.7	1	23	90	112	90	112	0.99
4	17	1.3e-05	0.00079	19.3	0.3	1	23	118	140	118	140	0.98
5	17	5.8	3.4e+02	1.6	0.1	2	23	233	256	232	256	0.78
6	17	0.072	4.3	7.6	0.3	2	23	310	332	309	332	0.96
7	17	0.19	11	6.3	0.2	1	23	651	673	651	673	0.95
8	17	6.3	3.7e+02	1.4	0.5	1	23	726	748	726	748	0.90
9	17	0.00026	0.015	15.2	0.2	1	23	793	816	793	816	0.93
10	17	0.0012	0.071	13.2	0.8	1	23	823	846	823	846	0.98
11	17	0.0031	0.18	11.9	1.6	1	23	878	900	878	901	0.96
12	17	0.37	22	5.3	0.2	1	23	1204	1228	1204	1228	0.91
13	17	0.00057	0.034	14.2	0.2	2	23	1237	1259	1236	1259	0.96
14	17	0.0089	0.53	10.4	0.1	1	23	1266	1288	1266	1288	0.97
15	17	0.002	0.12	12.5	0.3	1	23	1507	1529	1507	1529	0.96
16	17	0.0072	0.43	10.7	0.0	1	20	1539	1558	1539	1562	0.93
17	17	0.033	1.9	8.6	0.3	1	23	1570	1592	1570	1592	0.95

Sequence Information

Coding Sequence: ATGGCCATGAAGATGCTCTACCGTGGTCCAAGTACGCGATTGGAAACATTAATTGAGAAGATTCAGCAAAGCACGCACGGCGCGGGCCTGAACAGCACCTACCACTGTCAGTTCTGCGAGAAAACGTTCCCCCGGCTCGGTTATCTCAAGAAGCACGAACAGAGTCACACGGAACATATGCCATTCAAATGTGAATACTGCGCTCGGCTGTTCAAACATAAGCGCTCCCGGGATCGTCATACGAAGTTACACACGGGCGATCGGCGCTACCGGTGCCTGCACTGCGAGGCCGCATTTTCCAGAAGCGATCATCTGAAGATCCACATGAAGACGCACGACAACCAGAAACCGTTCCAGTGTACGATCTGCAACCGAGGCTACAACACGGCCGCCGCCCTAACCAGTCACATGCAGAACCACAAGAAGCAGCTCGCACTCACCGGTAGCCCCAACCTCACGTACAGCCCGCGCTCGACGACGAGCTCACTGTCGAGCGGTGGTGGCAGTGGCGGTGGCGGTAAACGCGCGTCCAAGTTTTCCTCATACTCCAGCGATCCGTTGCTGCTGATGGGCCGTGGCAGTGCCAAACTGTCGTCGGCGTTAGCGAAATCCGCATCCGCAAATGCGGCCAGCAATCGAACTCCGACGCCCGGCAGCACGGCCGGGGGAGGAACCGGATCGCAGCCGGATCTTCTCTCCTGTCCGTACTGCACGCGCACGGACTTCGGTACACTCGAGCAGCTTGGACTACACGTGCAATCGATGCACGGACACGGTTCAGCGTTGGGTTTGCTAGCCGGCGATGCGTCCCTCTCCTACTTTGCACCCCATTTGCGCGGTAGTCCAGGTGGAGGACGACGTGCCGTAACTCCCGACGCGGGCACTCTTGCGCTCGGTGCACTCGGTGGTTCACCGTATCCGCCGATCACGTGCGAATTCTGCACGATGAAGTTCCCGACCGTTCCGCTGATGTTTGCGCACCTGAAGACATCGCACCTGGACCGACTGACTGGGGCGGGACAGCAACGAAACTCGCCGAATGGAACCGGCAGTCCGATGGGATCACGACCTCCGAGCGGTTTTCATGGGCTAGAGCAGCTGCAGTTCAACAAGAGCCTGCTCGGAACTGCCTTCCCAGCATTCTACGGTGGAATGAACGCTGGGTCTTCTGCTAATATGCACGGCTTGTCGGGGAGCATCGTTAAAGCTGAGCCACGGCGCGATGAAAACGGCAACGAACCAAATGTGCCCGGTCGGAGGCGCAAAAGGACGCGTGGAGACGATGATGCGGAGGTTAGGAACCAGGAAGAGGGTACTCGACGCGATAATGGCGCAAAGGAAGACAGACATCGTGAGGAGGAGGATGATGATGATGATGAAGAAGTGGCCGAGGACGATGCGATGGATCGAAATCAATCCGCTGATTTTAAAGGAGAGACAGCAGACATGCGGCAAGAAGCGGATTGTGCACTGATTAAGCAAGAAAGTAAGGAAGACGGGGATCGAATTGATACGGAGACCGCATCCCCCTCGAGTTCGGCACGTGCGTCACCGTGTGATTCGTTGGAATCGCACACCCGTCCTGTTAGCCACCAATCCGCGCGTAACACACCCTCAATGAGCCCAGCGGAACAGCTTACCCCGACCGATCTCAGCCAGCCGAAGATTAAACGATTTAAACTGGAGGCCGTGGAGAATGAAGAAGCATCGGCCGGTCGAGCCCATGGTCGAGAGCATCCGAAGCAACCTTCCAGTGCGGTTCGTCGTGAAAGTGAGCAAAAGGAGCAACATCTAGCAGGTCTGCAAAGTAGCTCCCTGCACCATCAGAGTTCCACCACACAGATGCATCCATCCGGAGGACCGTCCAGTGGGATCCAACATCCACCAAAGCTGGGTGCTCCTACGCCGACCACAGCCCCACAGCAGCATGCTCATCAACCACCCGGCGCGTATCTCTGCAATCAGTGCAATGCCGCCCTACCAGACTTTGAATCGTTCCGGACGCACCTGAAGGCACACCTGGAGCAGAGTGCTGCGGCGAGTGCTGCGGCGAGTGCTGCAGCGGCAGCGGCCGCCGCTGCCACCATGAGACTCTCCGGGGAACACGCCGGACCCGGTAGTTCCGGAGGTACAAGCGCGTCCTCTTCCGCTAACAGCACCCTTTCCGTGACGGCATTTCTCTGCCAACAGTGTGGCGCTACGCTGAGTTGCCAGGCGGAGTACGAACAGCACACGATCGGGCACTATTTGGCGATGGCGGTGGAGTATCGGTGTCAAGCGGCCGGTACTGGGACGGCCGGTTGCGGTGGGAAGACTACGTTCGCGAAGGTGGAAGATCTGCACAAGCACCTATACGAGGGCCATATGCAGCTGCTCTACAAATGCACCGTCTGCGGGGAAAGCTTTGAGTCGAAGGTTCAGGTGCAGGTACATTTCGCGGTCAGCCATTCGGTGGAGGTGAAGCTGTACCGCTGTACCGCGTGTGCGGAAGCATTCCGTACGGAACGAGATTTTCGACAACATATTCGAAGTCGCCATTTGACAGCTGGTGCCGTGCAGTGCATGTTCTGTCGTATGGTTTGCTCTTCCGAGCTTGAGATGCACTTTCATCTTGCGTCACACGCCAGGAAATTCAAATGCCCTGCTTGTCCGGAGTCGTTCCACGTGGAGTTTCTGCTGGATCGCCACATCCAGACACACCACAGTCAGAAAGAATCGAGCTCACCGAATCGCCGAGACGCTAACGTTGGCCAAGCTTTAGCATCTTCCGCCGGCGGCAATGCGGCACCGAACGCTGGCGGAACGACATCATCGTCCACGGCAAATCCTTCGTCCACAGCGTCGACAACCACAACCGCAACGGCAACGGCAACGGCTGCCGTGGCGGCAGCAGCAGGACTGGATTATCTTCAACTGCACGGTCAGATGGCAGCAATGGCGGCAGCGGCCGCATGGCCAAGCCTTTACCAAACTGCCAACAAATTCTACGCCAACCCACTGCAAGTGGACACACTTAGTCAGTTGAAGCATCCACAGCATCTCCTACATGGCTTCTACGACACGATGCTCGGTAAAGCTCAACAGCAGCAGCAGCAACGGGCACCATTCCTTCCTGAAGCATCGGCCGGCCACGGTGGATCGAGTGGTAACAAAAAGAACCCTTTCACTAACCACTCACCTCCTGGAAACGCTCTGCTCGGCTTGGGATACAGTGCTATATCATCGACTGGTGGTTCTCAATCTCAACGGGGAGCAACTCATAATGGTTCCTCTTCGGGAATATATCCTCCGGAGGAAAACGGCAACCATGCAGGACCGAACACCAGCACCAGTAATGCCAAGCTTTATTCCCCAATTTCCATGATCCAGCGATATGGTGAAACCGCAGCGACAGGAGCAAGTGTAGTCAACTCTAGTACATCTCGAACAGGTGGTGGAGAGTCGCCCACGAGACAGTTGCTATTAGCAACGGATTTGCACAACGAACAGACGGGCAGGAAACTAAGCCAATCACAGCAACCGGCGGGTCCAAAGTCAGCATCGAACGCATCAGCGTCATCCTCCACCGGAGCAGTAGGCGTCACCGGTAGCTCCACGGCCAACTGTTGCTACAGCTGCGGCATCTGCGAGCGCTCCGACTTCAGCACGGAAAGTGAAGTGCAAACGCATCGCAAAATCGTGCACAACTTGAAGACGGGAGTTAGCCTGCGCTGCGCCTACTGTAATGGCGACTTCCGGTCGAGAAACGAGCTCGAAAACCACATGAAAATCGCTCACAATACGGGCGGCGGTAAGCACAAGTGTTTGATCTGTGACGAAATCTTTCCCTCGCCCGCGGTTCTTGCCGAACACAAGCTGTCCCACTGCAAGGTTGGTGCGTCCGGACGCTGCTCGCACTGTAGTCTACCGCTGCCGGACGTGCACACGTTCAAGCAACATCTGCCGGCTCATCAACAGCCACCTACTGGCTCATCGGCTTCAGGAACGTCTTCGGCAAATACGTCCTCGTCCAGTGGCTCCGCTGGAACCAGCGCGAACGGAGCGAATGCGAATCCGGCCGGGAATGCCAACGCCGAACAGGAACGGTTCCCGCAGCAGTGCATCTGCTGCCGGCAGACGCTTAATTCCGAGTTTGAGATTAGTCTTCATGCCAAGTTCCACACCAAATCTCCCGACACAAACGAACGCACATGTGCGCTCTGCCTTGAGCCGCTACCATCGCACCCAGAATCGGTTACCAAGATTTGCGAGCCCTGCCTGAAGCGCCACAACTTCCCTTCCAAGCTGCTCTCCATGAACTTTCTCCAACCGGCCGGTGCACCCTCGATCGCAGCTGGCTCTGGACATCCGGTTAATGGAGTCGCACAAGGACTCGCTGTGGGAGGAAGCGGTGTGGCATCCGCGGTTGATGGACGCTCACTCACCACTGCAGCGATTCCGCATGAGCAGCAGCACCCCCACGGCGTGAACGCCACGCGAGAAGCAGCACCGAACGCTTCGTCTGCCACAGCTTCCCTGTTTCAATGCAATCTCTGCAAAAAATCCTTACCGTCGGCACAGAAGTTACAGGAGCATCTAATCGATCATACGTTCGCGGGATGTGAGGAACGTGGCTACGTTTGTTACCTATGCTCGGCCGTCTTTACCTCGTCCGCTGGACTGCAGGCTCATCTGCCCATGGCACACTCGAATGCCGCCGCCAAACCGTACGACTGCGAACGTTGCGGTGTGGCGTACTTTTTCCGCGCCGAACTCGAGCACCATCTTATCGACCATGACCTTGGCAGGGCAGTCGGTATGGAGCAGCTAGAGGTAGCTAGAGCAGCCAACGAATGGTGTCCAAGCAAACACTCCTCGGAAGACGATAGGGTACCGATCGAGCAGCAAGCAGCGGGTCACATAAAGCAGGAACAGCAGGAACAGGATGACGCAATTGCGTGTCAGGGTCCATTTGAACCCGAAGAGGAACAGCCACAGACTGCCGAAGAGCATGGTGACGAGGAGCAGGAAGAGAACGAGGATCGAACACAAAGCGGCAATGGTTCGATGAACGAAAAGCTCCAGGGAAATACTTCCCCTCATGGTTATAAAGAAAAAAACGATGACCGAATCGATGAAGAAAGTGCCGAAAAAAGCGACCACGATGCGGACCGCAATGACCATTCGGACCATTCGGATCACGACCAGGAACCGGAACAGCAGGAAGACGACGGCGAGGAGGACGAAGAGTACATCGAGGTGGAACATACGCCGGTGGATGACGTGGGAGGAAAGGGAGCCAACGAACATCATCGTCGCTCGTCGAACATTCTACTCAACAGCGGCGCAAAAGAGTGTCCATCACTTAATGCAACCCTTTCCGTTGTTACTGCCGCCGAATGA
Protein Sequence: MAMKMLYRGPSTRLETLIEKIQQSTHGAGLNSTYHCQFCEKTFPRLGYLKKHEQSHTEHMPFKCEYCARLFKHKRSRDRHTKLHTGDRRYRCLHCEAAFSRSDHLKIHMKTHDNQKPFQCTICNRGYNTAAALTSHMQNHKKQLALTGSPNLTYSPRSTTSSLSSGGGSGGGGKRASKFSSYSSDPLLLMGRGSAKLSSALAKSASANAASNRTPTPGSTAGGGTGSQPDLLSCPYCTRTDFGTLEQLGLHVQSMHGHGSALGLLAGDASLSYFAPHLRGSPGGGRRAVTPDAGTLALGALGGSPYPPITCEFCTMKFPTVPLMFAHLKTSHLDRLTGAGQQRNSPNGTGSPMGSRPPSGFHGLEQLQFNKSLLGTAFPAFYGGMNAGSSANMHGLSGSIVKAEPRRDENGNEPNVPGRRRKRTRGDDDAEVRNQEEGTRRDNGAKEDRHREEEDDDDDEEVAEDDAMDRNQSADFKGETADMRQEADCALIKQESKEDGDRIDTETASPSSSARASPCDSLESHTRPVSHQSARNTPSMSPAEQLTPTDLSQPKIKRFKLEAVENEEASAGRAHGREHPKQPSSAVRRESEQKEQHLAGLQSSSLHHQSSTTQMHPSGGPSSGIQHPPKLGAPTPTTAPQQHAHQPPGAYLCNQCNAALPDFESFRTHLKAHLEQSAAASAAASAAAAAAAAATMRLSGEHAGPGSSGGTSASSSANSTLSVTAFLCQQCGATLSCQAEYEQHTIGHYLAMAVEYRCQAAGTGTAGCGGKTTFAKVEDLHKHLYEGHMQLLYKCTVCGESFESKVQVQVHFAVSHSVEVKLYRCTACAEAFRTERDFRQHIRSRHLTAGAVQCMFCRMVCSSELEMHFHLASHARKFKCPACPESFHVEFLLDRHIQTHHSQKESSSPNRRDANVGQALASSAGGNAAPNAGGTTSSSTANPSSTASTTTTATATATAAVAAAAGLDYLQLHGQMAAMAAAAAWPSLYQTANKFYANPLQVDTLSQLKHPQHLLHGFYDTMLGKAQQQQQQRAPFLPEASAGHGGSSGNKKNPFTNHSPPGNALLGLGYSAISSTGGSQSQRGATHNGSSSGIYPPEENGNHAGPNTSTSNAKLYSPISMIQRYGETAATGASVVNSSTSRTGGGESPTRQLLLATDLHNEQTGRKLSQSQQPAGPKSASNASASSSTGAVGVTGSSTANCCYSCGICERSDFSTESEVQTHRKIVHNLKTGVSLRCAYCNGDFRSRNELENHMKIAHNTGGGKHKCLICDEIFPSPAVLAEHKLSHCKVGASGRCSHCSLPLPDVHTFKQHLPAHQQPPTGSSASGTSSANTSSSSGSAGTSANGANANPAGNANAEQERFPQQCICCRQTLNSEFEISLHAKFHTKSPDTNERTCALCLEPLPSHPESVTKICEPCLKRHNFPSKLLSMNFLQPAGAPSIAAGSGHPVNGVAQGLAVGGSGVASAVDGRSLTTAAIPHEQQHPHGVNATREAAPNASSATASLFQCNLCKKSLPSAQKLQEHLIDHTFAGCEERGYVCYLCSAVFTSSAGLQAHLPMAHSNAAAKPYDCERCGVAYFFRAELEHHLIDHDLGRAVGMEQLEVARAANEWCPSKHSSEDDRVPIEQQAAGHIKQEQQEQDDAIACQGPFEPEEEQPQTAEEHGDEEQEENEDRTQSGNGSMNEKLQGNTSPHGYKEKNDDRIDEESAEKSDHDADRNDHSDHSDHDQEPEQQEDDGEEDEEYIEVEHTPVDDVGGKGANEHHRRSSNILLNSGAKECPSLNATLSVVTAAE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -