Basic Information

Insect: Anopheles farauti
Gene Symbol: Rreb1
Assembly: GCA_000473445.2
Location: KI915062.1:1139561-1147397[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00043 0.026 14.5 0.0 1 23 211 233 211 233 0.98

2 12 0.0003 0.018 15.0 0.9 1 23 249 271 249 271 0.97

3 12 1.1e-05 0.00065 19.6 5.2 1 23 277 299 277 299 0.98

4 12 0.041 2.4 8.3 5.0 2 21 532 551 532 552 0.94

5 12 0.13 7.5 6.8 0.0 1 20 597 616 597 618 0.94

6 12 0.0038 0.22 11.6 0.1 1 23 783 805 783 805 0.98

7 12 2.5e-06 0.00015 21.6 0.6 1 23 814 836 814 836 0.99

8 12 0.0014 0.08 13.0 2.3 1 23 842 865 842 865 0.97

9 12 0.00079 0.047 13.7 2.1 1 23 1220 1243 1220 1243 0.95

10 12 7.2e-05 0.0042 17.0 0.3 2 23 1654 1675 1653 1675 0.97

11 12 0.37 22 5.3 5.4 1 23 1681 1704 1681 1704 0.96

12 12 0.035 2.1 8.5 0.7 2 23 1862 1883 1861 1883 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00043	0.026	14.5	0.0	1	23	211	233	211	233	0.98
2	12	0.0003	0.018	15.0	0.9	1	23	249	271	249	271	0.97
3	12	1.1e-05	0.00065	19.6	5.2	1	23	277	299	277	299	0.98
4	12	0.041	2.4	8.3	5.0	2	21	532	551	532	552	0.94
5	12	0.13	7.5	6.8	0.0	1	20	597	616	597	618	0.94
6	12	0.0038	0.22	11.6	0.1	1	23	783	805	783	805	0.98
7	12	2.5e-06	0.00015	21.6	0.6	1	23	814	836	814	836	0.99
8	12	0.0014	0.08	13.0	2.3	1	23	842	865	842	865	0.97
9	12	0.00079	0.047	13.7	2.1	1	23	1220	1243	1220	1243	0.95
10	12	7.2e-05	0.0042	17.0	0.3	2	23	1654	1675	1653	1675	0.97
11	12	0.37	22	5.3	5.4	1	23	1681	1704	1681	1704	0.96
12	12	0.035	2.1	8.5	0.7	2	23	1862	1883	1861	1883	0.93

Sequence Information

Coding Sequence: ATGGATACCGGCAGCAGTAAGGTGGAGGTACCGTCGGCCACTACAGCGTCCCTGTCGGCGCCATCGGTGATAAAGACGGAAATGCCGGAACTACCCGACACAGAATCGCCGCAGCCAAGCGACACAGAGACCAGTGCGGATCCGGTGCTGCGGCGGGAGGAGGCGCAGGAGGAGGAGAAGATTACCAAAAGTGGCAGCGACGAGGAGGAGGAGCCGGAGGAGGAAGATGGATCAGTGGTTGGAGTGACGAAGTCCGACGCGTCTGCAGATGAACAGAACCACCACCAGCACAGCAGTAGCACCAGCAGTAACCAAAGCCATCACCATCAACCGGTGAGCAGACAGCGAGGGGAGCATCTCCACCAGCTCACCGACGACATGCTGCGACGGAAGACGCTGAAAGCCAGCGGAGGAAGTAGTGGTGGTGGTGGTGGTCGCGCCAAGCGCTCGCTGGAGTCCACGGCGGAGATGTTGCTGCAGCAGCAGCGCCAGCAAATGGCGGCGGCAAACGCGCTGCCAGCGACGCACATATCGACACCGACGAGTGGGGGCGGGAAGCAGCGTGGTGGGACGGTGCGCCGTCCGGAGGAGAACGACGACGAGGAGGACGACCCTTCGTCGGAGAAGCGTTTCGTTTGCCCGATCTGCGAGTGGGTTTCGCCGACCCAGCGCGCCTTCACCGAGCACATCCGGTTGCACAACGCCGAATCGGAGTCGGCGACGACGGCCGTCGCGTCCGCCAGCTTCTGCTGCAAGATCTGCTCGAAGGTGCTGTCGTCCGCGTCCTCGCTCGATCGGCACGTGCTGGTTCACACCGGCGAGCGTCCGTTCAACTGCAAGTACTGCAGTCTTACGTTCACGACCAATGGGAACATGCACCGGCACATGCGCACCCACAAGTACCCGTCCGGGCGGGACAGCTTCGAGGGTGAGACTGGCGGCGGTGGGGGTGTGGGTGGTGCCGGAGCCAGTGCCAGCACCGGTGGAGGCTCTTCGTCGGACGGGAGCGGAGGAGGTAGCAAAGCGGGGCGGGGTCGTACCACCACCAACACACCGACCGGTGGTGGCCGCCATTATCGCAAGAAGAAGGAGGACGCCGGGGAGGACGGGGACGGCGATGAGGACGACGAGTACCATCGGCAGCCCAGAAAGAAGAAGAAGAGAGCGTTGTTTACGTCCGGCGGGGGTGGGCAGGGCGACGGTGACGACGAGCTGATGGGGACGGCCATGTTGGAGGAGCAGCCATATCGCGAGCCGCTCGAAACGGACGAAGATATGGCGGCGATGGCGGCCATGGCGGCGTCGGTGGCGGCTCTCAACAGCGAGGCGGATGAGGAGGATGAGGAGCAGGAGCAAGAGGATGAGGAGAGCGAGGAGAAGGTCGGCGGCAAGCAGCGGAAGGGCAAGCTGGGGAGCGATCGGCGCCGGTCGTCGCCCAACTACCGTAAGGGGCGGACGACAACCATCAACAACAACCTGGTGGAGGCAGCGAGCGGGCAGCGCTACTGCTGTCCCGTGTGCGAGCGGAACGACTTCGCGAGCATGCTCGCGCTCGAGCAGCACCTCGACCAGGAGCATCCGAGCGTGCCGGCCAAGTGTCGGCACTGCGACGTCGTGTTCCGGAGCCACAAGACGCTGAACGCGCACCGGTGCAGCAACAACAACTACCAGAACATCACGCCCGGCTTCAAGGATCTGACGTTCGTGGACTTTTCGAGCGAGAAGTTTCCGCTGATCGCGAAAAACCTGTGCGAGCAGAGCATCCGGACGCCGGTGACGAGCCAGAAGTACGAGTGTGCCCGCTGCTACCGGGCGTTCCCGAGCGCGAAGACGCTCGCGATGCATGCGATGGATTGCGGTGGGGTTGGGCAGCAGAATCGGTCGGTGGGTACGGTGTCCGAGGCACCGACGACGCCATCATCGCTGGACAAGTCGTTCTCGTCGCCGGTACCGTCCGGGTTGAAGCAGGAACCGCTCGGTTCACCGACCGGTGGTGCGACCCAAACCACCACCAACGCCCTCCCGATGTACTACGCGTCCATGTACCACGGTGGACACCAGCAGCAGCAGCAGCATCACCACCAGCACGCGATGGACGGCGGGAAGGATCTCGCGGACATCCAGTCGATCATCAACGTCGCGTCGTCCGGTGGGCTGTTCGGGCGGCAGCTGGATGGTGGTGGCAGCCATACGCCGCTCTCCGGACTGCTGGACGGCACCGGCGGGAAGGATGGGACGGGCAGTGACGGTGGCATGTACGCCCACTCGACCGGTTCGCGCGACGAACCGGAGGAAGCGCAGGACGCGTTCACGGCCGAGTTCCGGCGGATGAAGCTGCGCGGCCAGTTCCCGTGCCGCATCTGCACGGCGGTGTTTCCGAACTTGCGCGCGCTCAAGGGCCACAACCGGACGCACGTGACGGCGGCCGGACCGGGCCCGTACCAGTGCAACATGTGCCGGTACGTGGTGAGCGACAAGGCGACGCTGATCCGGCACATGCGCACGCACAATGGCGACCGGCCGTACGAGTGTGCGCTCTGCAACTACGCGTTCACGACGAAGGCGAACTGCGAGCGGCACCTGCGCAACCGGCACGGGCGGACGACGCGCGAGGAGGTGAAGCGGGCGATCATCTACCACCCGTCGGAGGACTCGTCGTGCGACGATCCGCTCAAGAAGCTGCACATGTTCAACACACCGCCGGCCGACGGGTCGTACACGCCGACGATGCTGGCGGCCGCGACGTACCAGGAGGACCAGTCGTCGTCGCTGCCGGAGGCGCGCAGCAGTACGCCGCTGTCGTCGCAGCAGTTCAAGGACATGCTGCTGCCGGCGGTGCCGTTGAGCTTTGTCGGGGCGCCGCACCAACATCCGCTGCTGGAGACGAGTCTGCTGCTGCAGACACCGCAGACACCGGGTGGGGCGATTGCGGCGGCGAAGATACAGGTGAAGAGTCTGGAGAAGCTGAACCAGCTGACGCCTCCGCAGGAGGACGACGTGCTCGTTGATGAGGACGAGGAACAGGAGGAGGAGGAGGAGGAGGACGAGCTGGACGAGCATCATCATCATCATCGCGTTGGTTCGTCCGATGGCGGGCCGAAGAAGAAGGAGCCGACGGCTTCGGCCCGCCCGATGGATCTCAGTATGGACGCGTTGGATCTGAGCAAGAAGTCGACAACGGCGGTGGCGAACAGTCGTAAGGTGGTCGCTTCGATCCCACCAACCTTGCTGTCGACCGATGGCGAAGACGAAGAGGAGGATGCTGGGGAGGAGCAGCGACACCACAGACATCGCGCCAGCTTGAACGGTGTCGAGGGCGGCGTTAGCAAGCGTCCTCCTGGTGGTGTGTCTATCAAACAGCGTGACGTGGACGTGTCCGCTGCCGCCGCCGCCGCCGCACCTTTCCTGCCGAACTCGATGCTGGGACCGACGGCTGCGCTGAGCGATTTCCTACCAAACCTGGCGGCGGCGGCGGCTGTTACGGCGGCGGCGGCAAACAGCGTCGGTGGCCGGAACCATCACCACCATCAGCTGCAGATGCTGATGAACCCGTTCTATCCGCCACCGACGGCGGACACACCTCCGAATAGTATGGTCATCAAGAACGGGGTGCTGATGCCGAAGCAGAAGCAACGCCGCTACCGAACCGAGCGCCCGTTCGCTTGCGAGCACTGCTCCGCCCGGTTCACGCTGCGCTCCAACATGGAGCGGCACATCAAGCAGCAGCATCCCCAGTTTTGGTCCCAGCGCCAGCGCGGTGGACATCATCTGATGCGCCGCAGTGGCGGTGGAGGAGGTAACAGCAGTAGTAGCGCTGGCGCTGGCGGTGGCATGGTTGCCAGCGGCTCCGTTGGTTCGCTTGCCGCCGCACTGCAGGGCGCGTTCGGTGGGTCGCCCGGCGGTGGCGGGGGTGGGGGTGGAGGCGCCATCTCCGACCAGGTGAAGTACGCCATTTTGGCGCAGCAATCGGGCAAGGGTGGGGCGGCGGCGGCGGCGGCGGCGGCGATGCGTGGCAGTGCTGCCAGCAACCAGCCGGAGCCGGCGAGTCACCTGAACCCGCTGCTCCACAACATGATCGTGCAGGCGGGAAGCATGCGCGACGAGACGGAGGACGAGGAGGACGAGGAGCAGGACGTGCCGTCGTACGATGGGGCGACCCCAGTCCGCCATCGGCGACGCCGTCGCCGCCTACAGTCACACCTCGACCACGACGTGGAACTCCTGCGGCGAACTTACACCGCTACCCACCAGATGGCGCACGATGGCGGCGAGGAACGCCACCAGTACAAGAAGGAGGAGACGAGCCCGATTGCTCCCGAGCAGCCAAACGAAGATGGCGACGGGCATGAGGGTAATGGCGACGAGGAGGAGGAGGAGGAGGAAACCGATGCCCAGCTCGTGATCGACGAGGACGAGGAGGAAGCGGGCAGCGTGGCGAAGATGCCAAAGCTGGACGAACCGGTGGCTCCGGCGGAGATGAAGCCGTCGAAGTTCAAAGTCGAAGCGAACGGCAGCCTCGAACCGGACGTCCCGGTTAGTTTGCATCGCATCCTGAAGCAGAAGCTGGAAGAGCGACACCCGAAGGAGGTGGAAGCGGGCGAGAGTGTGGCGGCGCCGGTGGAGATGAAGCCGTGCAAGCAGCCGCGAAAGGTGTCGTCGGGTAGTAGTAGCAGCGGGCTGAGCGGACAGGACGAAAGTGGCGGCAGCAACAGCGACCTGGTGCCGGTGGCGAAGCTGCTGGATAACGCGACCAATCCGGTGCTGGAGAGTTACTTCAGCAGACCGGAGGTGCAGGTACCGCTCGCCCAGGACCACAGCGACGAGGAGGGCCTGGTCGCGTCCGGTTCCGCCTCGGAGAGCAACAACTCCGGCACGGACGACCCGAACCCGTCGGCGGTCGAGCTCGCCCACCAGCACCAGAAGAAGAAGTCGGCGTACAGCTTGGCCCCGAACCGCGTCAGCTGCCCGTACTGCCAGCGCATGTTCCCGTGGTCGAGCTCGCTGCGCCGGCACATCCTCACGCACACCGGCCAGAAGCCGTTCAAGTGTTCGCAGTGCACGCTGCTGTTTACGACCAAATCCAACTGCGATCGGCACCTGCTGCGCAAGCATGGGGACGTCGAGTCGGCCGTCTCGATACCGGTGCCGATCGACGATCTGCTCGACCCGAAACCGGAACCGATACCGGTTGCGGTCGCGGAAGCGATGTGCAAGAAGGTGACCGGCAAGGGGCGGGGTGCGGCCGTCGCCTCGGTGTCCACCCTTGCGCTGAAGGGCCCGGAGCAGCTGTCGGAGGAGGAGGAAGCGCACCAAGCGCACCAAGACACGCACCAGCCGAGCGGCACTCTCCACAAGCCAAACGAGCCATCGGACGAGGATGAGCAGCGGCGGTCGGACGGAGCGAAGGAGGAGAGCGGCAGTGAGGAGAGCGGGAGCGAACAGCAGCCCGTCGTGAACCCCAAGCCGGAAACGAACGGTGACGAGGGCGGCGAACATCCAGCGCGGGTCGATTCGAAGCAGGAACGTTCCCCGGACGTGGACGGGGAAGCTCACCGAAGGCGTCAGGACAAGCGCGCGGACGTTGTCTGCGCATTCTGTATGCGTCGCTTCTGGTCGACGGAAGACCTGAGACGGCACATGCGGACGCACTCCGGCGAGCGTCCGTTCCAGTGTGACCTGATCGGGAACCTGCTCGGCATCAGCGACCAGGGTATCCTGAGCCAGGTGCTGCTATCTTCCGCTTCCGAGGCTGCCAAGCTGCTTGGAGTCGACAACTAA
Protein Sequence: MDTGSSKVEVPSATTASLSAPSVIKTEMPELPDTESPQPSDTETSADPVLRREEAQEEEKITKSGSDEEEEPEEEDGSVVGVTKSDASADEQNHHQHSSSTSSNQSHHHQPVSRQRGEHLHQLTDDMLRRKTLKASGGSSGGGGGRAKRSLESTAEMLLQQQRQQMAAANALPATHISTPTSGGGKQRGGTVRRPEENDDEEDDPSSEKRFVCPICEWVSPTQRAFTEHIRLHNAESESATTAVASASFCCKICSKVLSSASSLDRHVLVHTGERPFNCKYCSLTFTTNGNMHRHMRTHKYPSGRDSFEGETGGGGGVGGAGASASTGGGSSSDGSGGGSKAGRGRTTTNTPTGGGRHYRKKKEDAGEDGDGDEDDEYHRQPRKKKKRALFTSGGGGQGDGDDELMGTAMLEEQPYREPLETDEDMAAMAAMAASVAALNSEADEEDEEQEQEDEESEEKVGGKQRKGKLGSDRRRSSPNYRKGRTTTINNNLVEAASGQRYCCPVCERNDFASMLALEQHLDQEHPSVPAKCRHCDVVFRSHKTLNAHRCSNNNYQNITPGFKDLTFVDFSSEKFPLIAKNLCEQSIRTPVTSQKYECARCYRAFPSAKTLAMHAMDCGGVGQQNRSVGTVSEAPTTPSSLDKSFSSPVPSGLKQEPLGSPTGGATQTTTNALPMYYASMYHGGHQQQQQHHHQHAMDGGKDLADIQSIINVASSGGLFGRQLDGGGSHTPLSGLLDGTGGKDGTGSDGGMYAHSTGSRDEPEEAQDAFTAEFRRMKLRGQFPCRICTAVFPNLRALKGHNRTHVTAAGPGPYQCNMCRYVVSDKATLIRHMRTHNGDRPYECALCNYAFTTKANCERHLRNRHGRTTREEVKRAIIYHPSEDSSCDDPLKKLHMFNTPPADGSYTPTMLAAATYQEDQSSSLPEARSSTPLSSQQFKDMLLPAVPLSFVGAPHQHPLLETSLLLQTPQTPGGAIAAAKIQVKSLEKLNQLTPPQEDDVLVDEDEEQEEEEEEDELDEHHHHHRVGSSDGGPKKKEPTASARPMDLSMDALDLSKKSTTAVANSRKVVASIPPTLLSTDGEDEEEDAGEEQRHHRHRASLNGVEGGVSKRPPGGVSIKQRDVDVSAAAAAAAPFLPNSMLGPTAALSDFLPNLAAAAAVTAAAANSVGGRNHHHHQLQMLMNPFYPPPTADTPPNSMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHIKQQHPQFWSQRQRGGHHLMRRSGGGGGNSSSSAGAGGGMVASGSVGSLAAALQGAFGGSPGGGGGGGGGAISDQVKYAILAQQSGKGGAAAAAAAAMRGSAASNQPEPASHLNPLLHNMIVQAGSMRDETEDEEDEEQDVPSYDGATPVRHRRRRRRLQSHLDHDVELLRRTYTATHQMAHDGGEERHQYKKEETSPIAPEQPNEDGDGHEGNGDEEEEEEETDAQLVIDEDEEEAGSVAKMPKLDEPVAPAEMKPSKFKVEANGSLEPDVPVSLHRILKQKLEERHPKEVEAGESVAAPVEMKPCKQPRKVSSGSSSSGLSGQDESGGSNSDLVPVAKLLDNATNPVLESYFSRPEVQVPLAQDHSDEEGLVASGSASESNNSGTDDPNPSAVELAHQHQKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSQCTLLFTTKSNCDRHLLRKHGDVESAVSIPVPIDDLLDPKPEPIPVAVAEAMCKKVTGKGRGAAVASVSTLALKGPEQLSEEEEAHQAHQDTHQPSGTLHKPNEPSDEDEQRRSDGAKEESGSEESGSEQQPVVNPKPETNGDEGGEHPARVDSKQERSPDVDGEAHRRRQDKRADVVCAFCMRRFWSTEDLRRHMRTHSGERPFQCDLIGNLLGISDQGILSQVLLSSASEAAKLLGVDN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -