Basic Information

Insect: Anopheles farauti
Gene Symbol: PPP2R5D
Assembly: GCA_000473445.2
Location: KI915043.1:11956851-11969183[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 4 2.4e+02 2.1 1.2 2 23 184 206 184 206 0.94

2 16 0.0015 0.087 12.9 0.2 2 21 216 235 215 236 0.95

3 16 0.51 30 4.9 2.0 1 20 243 262 243 264 0.93

4 16 0.039 2.3 8.4 0.1 3 20 393 410 392 412 0.93

5 16 0.013 0.78 9.9 2.6 1 20 419 438 419 440 0.94

6 16 0.21 12 6.1 2.9 2 23 516 538 515 538 0.93

7 16 0.6 35 4.7 0.1 1 19 551 569 551 571 0.94

8 16 0.0021 0.13 12.4 0.1 1 21 581 601 581 606 0.95

9 16 0.28 16 5.7 0.3 1 23 665 690 665 690 0.93

10 16 0.014 0.81 9.8 0.4 2 20 707 725 707 727 0.94

11 16 0.00016 0.0097 15.9 1.0 1 23 734 757 734 757 0.93

12 16 1.5e-06 9.1e-05 22.3 0.4 1 23 764 786 764 786 0.98

13 16 0.00016 0.0097 15.9 0.3 1 23 792 815 792 815 0.95

14 16 2.3e-05 0.0013 18.6 1.0 1 23 821 843 821 843 0.98

15 16 0.028 1.7 8.9 3.9 1 23 849 872 849 872 0.92

16 16 0.00019 0.011 15.7 2.0 1 23 878 900 878 900 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	4	2.4e+02	2.1	1.2	2	23	184	206	184	206	0.94
2	16	0.0015	0.087	12.9	0.2	2	21	216	235	215	236	0.95
3	16	0.51	30	4.9	2.0	1	20	243	262	243	264	0.93
4	16	0.039	2.3	8.4	0.1	3	20	393	410	392	412	0.93
5	16	0.013	0.78	9.9	2.6	1	20	419	438	419	440	0.94
6	16	0.21	12	6.1	2.9	2	23	516	538	515	538	0.93
7	16	0.6	35	4.7	0.1	1	19	551	569	551	571	0.94
8	16	0.0021	0.13	12.4	0.1	1	21	581	601	581	606	0.95
9	16	0.28	16	5.7	0.3	1	23	665	690	665	690	0.93
10	16	0.014	0.81	9.8	0.4	2	20	707	725	707	727	0.94
11	16	0.00016	0.0097	15.9	1.0	1	23	734	757	734	757	0.93
12	16	1.5e-06	9.1e-05	22.3	0.4	1	23	764	786	764	786	0.98
13	16	0.00016	0.0097	15.9	0.3	1	23	792	815	792	815	0.95
14	16	2.3e-05	0.0013	18.6	1.0	1	23	821	843	821	843	0.98
15	16	0.028	1.7	8.9	3.9	1	23	849	872	849	872	0.92
16	16	0.00019	0.011	15.7	2.0	1	23	878	900	878	900	0.98

Sequence Information

Coding Sequence: ATGCATCGATCGACTAAGCGCAAGAAGGTGTCCGATGCCAGTGAGGACATGTTGGCACGGTGCTGCATCTGCTCCAAACAACCTGCAGGCTCATTACTAGAGCTAGCAACAGTGGTTCAACAAGGAAGGGGGACAACGATTGCAGATATAGTGGAGCAGGTCGCAGGCATCAAAGTAAAACAAGTTCAGCAACGCATTTGTAGCTCCTGTTGGACTAAAATAAAAGCGGCCTTTACAATACAGAATGAAATTCGTGGCTCGGGGTGCATAGGTGAAGCCGCGGAAGAGGACACAGAAAGCGATACGCAGGAAGGCTGTACGGAGCTGGTTGTAAAGGAGGAACAAGTAGAGTATTTGATCGAATATCTCGAGTCGGATGTTGACGACATTAAACCGGAAGAGGAAAACGTTGACGAGCAATCGCACGCTGACGAGCGGCATGAGAAAGGGTCGGGAAAAGTAACACGCCAGTTTGTAATGCCCCGTCAAGCGTCGATCGTGAAGGATGTCCTGCACGAGCAGTACCGAGCGCTGGAAGTGTCTGGTGAGCGCTGCTGTGGCTGTAGCTTCGTGGGCGAAACGCGCAAGGAACTATTGCAGCACTCGGAAACAGTACACGCCGTCGAGATACAAGATTGTGGCGATTATTGTCCTATATGTTTCTACAAATTCTCCTCCGACCGGCAGCTCGAGCAACATATCCGAGAGTTTCAGCAACCTTTAATGTTCGTATGCCTGCGGTGTAATCGATTTTACAATCAACATAGTAGGCTTGTCAACCATTTTCTGCGCTGCGGCGAAAAGTTAGATGGAGAATTGAGTGAAAGTGAAATAGAATACACAGACGTGGCCGAGGGTGATGTGATTGAGCAGGAGAACGAGGGTGAGGATGATGTTGAGAGTGGCGAATATTACTTTACCGAAGAAGCTACTGCAACTGAAGACTTCGGTTCACGTAAAACATTCTCCGACCCACGGATGATGCACCGCTTTCGGAAACAATTTGAAGAAATATTTGCCAACGAAAAACTTTCCAGCGACCTGACCGAGGAGGGCCTAAATGTGCAGCAAGTCCAAATTGCAGCTCAGCAAACGTTTACCACGTTTAACGGAATGATGATCGACCACGGTAAGCTGGTCCATCTAGCCGAACAAAGCGCTCGAGATGGCCCATCGTGCGGGCAGTGTGGGGTCCGATTCCCGAATGAAATGGAGCTCGTTAAGCATCTCAGTTTCTTCACAACCAAACAGCTGTTTTTCTGCACGATTTGCGATAAATCGTTTCTTACGCACGACAGCTTACGATATCATCAGGCGCACGACGAACGACACCGTCAGCTGCTGCACGAACAATACCGTATCTTGACAACGGATACGTTCGTCGAGCTCGACCAGCACGACGTGGCGAACGAGCTGCATAAGCTGTTAGCCGAGAAGGTTACGCACCGGTCAAAGATCGTGCGAGGTATTGAGATGCCGGAGGATCGTTTTATAGTGGGCGTCGAAGAGCACAACAACTACCGGATCCTTACCGTGCAAGGAGTAAGCTGCTGTGGTTGTACCCGTCTTTTCGACACCGAGGCGGACCTTAATCGTCATTCGAAGCACGAGCACTATCAGCCGCCGGTGTCGATTGGCCGTACGTGCGGTCACCAGTGCGACATCTGCTACGCCGTTTTCGACTTTGAACGGGGGCTTACCATGCACAACGCGATAAGACGCGCTGGAAAGAAGCGCTTGTTTGTCTGCAAGCTATGCGGATTGCTTTTTGCGAAAAAGTTTGGCCTCGCGCGACACATGCAGCTGGCACCGAACCATCTGTCGCGGTTAATTGTGGATGCGGAACGCAATGGTGATGGTGATTCGGAGGCATCGGGTAGTGGCACGGTACCGACCGATGCTATCGAATCGGATCCACGCGTGCAGGAAGCGTTACAGTTGCACCGCTCGGTGGAGCAGGCAGGAGTGGAGAAGGCGGGCCATCTCGTTTGGTATCGCTGCTGTCTGCCCAAGTGTCCGGAACTGTTCACCGAAGAGGAGGCCTTACTAGAACACACACGGGAAGAGCACAATGGACGGCGTAAGGAAAACGAACAGGAACGCAAACAAAATACGAACGTCTGTCCCGGTTGCTGTAAAGCGTTCCCAACGTTGTCCAACCTCATGTGGCATCGATTTCAACGATTCGTACCGCGCAAACACGACTGCACCCAGTGTGGCAAGACGTTCGACAAGTGGCCCAAGCTGAAGATGCACATAGAGCAGGAGCACAGTGAAACGCCACCGCGCTTCGAGTGTACGGAGTGTGGAAAGGCGTTCGTGGTGCGATCGCGGCTCAAGACACACATGCAGATACACAGCGACCGGAAGGACCACGTGTGCGATGTGTGCGGCGATGCATTCGTCAACAAGGGACTGCTGAAACGCCATCGAAGGGCTCTGCACTCGACGGAGCTGCTGTTTGAGTGTAAGCTCTGTACGAAAAAGTTTGCCGTATCGGAGAAGCTCAAGATCCACCAGCGAGTACACACCGGAGAACGTCCGTACGCATGTGGCTATTGCCATCGTACCTTCATCCACTACACCGATCGTAAACGACACGAAATGGCTACACACACGGGGGAGCGTCCGCACAAGTGTGAGCTTTGCCCAGCATCGTACATACGCAAGCATGAGCTAGCGTTGCACATGCAGAAGCATGGACCGGGAGACAGCGCAAGTGTTCGGGGTGATCAAGAATACTACGAAATCGAAACGCTACCCCCGCTGAAGGATGCCGATCCGACCGAGCGCGAGGAGCTGTTCATCCAAAAGCTGCGGCAGTGCTGCGTGTTGTTCGATTTCTCCGAGCCGCTCAACGACCTGAAGTATAAGGAGATCAAGCGCTGCGCGCTGCAAGAGATTGTCGAACATCTGAGCAACCAGAGCAACGTGATTACGGAGGCAATCTATCCGGAGGCGTTTAACATGGTCGCGATCAACCTGTTCCGGACGCTGCCGCCCTCCTCCAACCCGAACGGTGCCGAGTTCGATCCGGAGGAGGACGAACCAACGCTGGAGGTGTCCTGGCCGCACCTACAGTTTGTGTACGAGCTGTTTCTGCGCTTTCTCGAATCGCCCGACTTCCAGCCGAACGTGGCGAAGCGCTACATCGACCACAGCTTCATCCTGAACCTGCTCGAGCTGTTCGATTCGGAGGATCCGCGCGAACGTGACTTCCTAAAGACGGTGCTGCACCGGGTGTACGGGAAGTTCCTGGGGCTGCGGGCGTTCATCCGCAAGCAGATCAACAACATCTTCTACAAGTTCATCTACGAGACGGAGCACCACAACGGGATCGCGGAGCTGCTGGAGATACTGGGCAGTATTATCAACGGGTTTGCTCTGCCGCTAAAGGAGGAGCACAAGCAGTTCCTGCTGAAGGTCCTGCTGCCGCTGCACAAGGTGAAGAGCCTGTCCGTGTACCACCCGCAGCTGGCGTACTGTGTGGTGCAGTTCCTCGAGAAGGACGCGAGCCTCACGCAGCCGGTCATCAAGTGTTTGCTGAAGTTTTGGCCGAAAACGCACAGCCCCAAGGAGGTGATGTTTCTGAACGAGCTGGAGGAGATACTGGACGTGATCGAGCCGGCCGAGTTTCAGAAGGTGATGGAACCGCTGTTCCGCCAGATCGCGAAGTGCGTCTCGAGCCCACACTTCCAGGTGGCGGAACGGGCGCTCTACTACTGGAACAACGACTACATCATGTCGCTGATCTCGGAGAACTCGAAGGTCATCATGCCGATCATGTTCCCGGCACTGTACAGCAACAGCAAATCGCACTGGAACAAAACGATCCACGGGCTGATCTACAACGCGATCAAGCTGTTCATGGAGATGAACCAGCTGCTGTTCGACGAATGCCACCGGAAGTACCAGGCGGAGCAGGAGACGGAGCAGGAGAAGCTGGCGCAGCGGGAAACGCTCTGGCAGCAGATGGAAGATTTGGCCGTACGGAACAGCAAGCTGACGCTGAACGACAGTGCGGCCAGTAGTGAACCGAACAGCAGCTCGTCGCCATCGCGATCGGCACTGCTTGTGCTGCGGAATTTGGATCTAGACGCTGAGGTAAAAATAGTTAACCTCTTCGCCGGTGAGCACCTGGCGGAAGAGTTCATCGCCATCAACCCGGACCACACGGTGCCGACGCTCGTCGACGAGGACTACATCCTGTGGGAATCGAAAGCGATCGTTACGTACCTTGCGGAGCAGTACCAGCCGGGATGTTCGCTGTATCCGAATGATCCGAAAAAGCGGGGTCTCATCAACCACCGACTGTACTTCGATTCCGGTACGCTGTTCGTGGCGCTGCGTGACGTGCTGATGTCCGTGTTGCGTTCGGGCGCAACCACCATCGCGCAGGACAAGAAGGACAATGTGCACAAGGCGCTGGCGAAAATGGAAGCGTTCCTGGACGGGTGCGATTGGGTGACCGGCGATGAGTGCAGCCTGGCCGATCTTTGCATGCTGGCGAACGTGGCCACACTGAAGCACATCGGTGTAGGATTCGAACCGTATCCGAACATTAGCGGGTGGTATGAACGATGCCAGGAGCTGGCCGGTTTCGACGAAAACGACGAGGGCGCCAGCTTCATCGGGAACGCCGTGACGTCGAAACTTGAGGAACCATTTTAA
Protein Sequence: MHRSTKRKKVSDASEDMLARCCICSKQPAGSLLELATVVQQGRGTTIADIVEQVAGIKVKQVQQRICSSCWTKIKAAFTIQNEIRGSGCIGEAAEEDTESDTQEGCTELVVKEEQVEYLIEYLESDVDDIKPEEENVDEQSHADERHEKGSGKVTRQFVMPRQASIVKDVLHEQYRALEVSGERCCGCSFVGETRKELLQHSETVHAVEIQDCGDYCPICFYKFSSDRQLEQHIREFQQPLMFVCLRCNRFYNQHSRLVNHFLRCGEKLDGELSESEIEYTDVAEGDVIEQENEGEDDVESGEYYFTEEATATEDFGSRKTFSDPRMMHRFRKQFEEIFANEKLSSDLTEEGLNVQQVQIAAQQTFTTFNGMMIDHGKLVHLAEQSARDGPSCGQCGVRFPNEMELVKHLSFFTTKQLFFCTICDKSFLTHDSLRYHQAHDERHRQLLHEQYRILTTDTFVELDQHDVANELHKLLAEKVTHRSKIVRGIEMPEDRFIVGVEEHNNYRILTVQGVSCCGCTRLFDTEADLNRHSKHEHYQPPVSIGRTCGHQCDICYAVFDFERGLTMHNAIRRAGKKRLFVCKLCGLLFAKKFGLARHMQLAPNHLSRLIVDAERNGDGDSEASGSGTVPTDAIESDPRVQEALQLHRSVEQAGVEKAGHLVWYRCCLPKCPELFTEEEALLEHTREEHNGRRKENEQERKQNTNVCPGCCKAFPTLSNLMWHRFQRFVPRKHDCTQCGKTFDKWPKLKMHIEQEHSETPPRFECTECGKAFVVRSRLKTHMQIHSDRKDHVCDVCGDAFVNKGLLKRHRRALHSTELLFECKLCTKKFAVSEKLKIHQRVHTGERPYACGYCHRTFIHYTDRKRHEMATHTGERPHKCELCPASYIRKHELALHMQKHGPGDSASVRGDQEYYEIETLPPLKDADPTEREELFIQKLRQCCVLFDFSEPLNDLKYKEIKRCALQEIVEHLSNQSNVITEAIYPEAFNMVAINLFRTLPPSSNPNGAEFDPEEDEPTLEVSWPHLQFVYELFLRFLESPDFQPNVAKRYIDHSFILNLLELFDSEDPRERDFLKTVLHRVYGKFLGLRAFIRKQINNIFYKFIYETEHHNGIAELLEILGSIINGFALPLKEEHKQFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDASLTQPVIKCLLKFWPKTHSPKEVMFLNELEEILDVIEPAEFQKVMEPLFRQIAKCVSSPHFQVAERALYYWNNDYIMSLISENSKVIMPIMFPALYSNSKSHWNKTIHGLIYNAIKLFMEMNQLLFDECHRKYQAEQETEQEKLAQRETLWQQMEDLAVRNSKLTLNDSAASSEPNSSSSPSRSALLVLRNLDLDAEVKIVNLFAGEHLAEEFIAINPDHTVPTLVDEDYILWESKAIVTYLAEQYQPGCSLYPNDPKKRGLINHRLYFDSGTLFVALRDVLMSVLRSGATTIAQDKKDNVHKALAKMEAFLDGCDWVTGDECSLADLCMLANVATLKHIGVGFEPYPNISGWYERCQELAGFDENDEGASFIGNAVTSKLEEPF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -