Basic Information

Insect: Anopheles farauti
Gene Symbol: ZFY
Assembly: GCA_000473445.2
Location: KI915045.1:5577084-5581609[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 1.8e-05 0.0011 18.9 2.7 1 23 528 550 528 551 0.96

2 8 0.14 8.4 6.6 0.0 1 23 690 713 690 713 0.94

3 8 1.3e-06 7.7e-05 22.5 0.3 2 23 720 741 720 741 0.97

4 8 9e-05 0.0053 16.7 0.6 1 23 747 771 747 771 0.99

5 8 1.1e-05 0.00062 19.6 2.6 1 23 780 802 780 802 0.96

6 8 2.2e-05 0.0013 18.6 0.4 2 23 813 834 812 834 0.96

7 8 1.4e-07 8.1e-06 25.6 0.9 1 23 840 862 840 862 0.97

8 8 0.00067 0.039 14.0 1.1 2 20 870 888 869 890 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	1.8e-05	0.0011	18.9	2.7	1	23	528	550	528	551	0.96
2	8	0.14	8.4	6.6	0.0	1	23	690	713	690	713	0.94
3	8	1.3e-06	7.7e-05	22.5	0.3	2	23	720	741	720	741	0.97
4	8	9e-05	0.0053	16.7	0.6	1	23	747	771	747	771	0.99
5	8	1.1e-05	0.00062	19.6	2.6	1	23	780	802	780	802	0.96
6	8	2.2e-05	0.0013	18.6	0.4	2	23	813	834	812	834	0.96
7	8	1.4e-07	8.1e-06	25.6	0.9	1	23	840	862	840	862	0.97
8	8	0.00067	0.039	14.0	1.1	2	20	870	888	869	890	0.94

Sequence Information

Coding Sequence: ATGTCGACGCTAAAAGCACGCGATACGGTGCGGATTACGCATCCGGAAAAATTGCTCATCCGAACGACGGTGGAACCGGTTGCCGCGGTGGCAGCACCATCCGTCGCTACCGTGTTACGTTCGCCAACGACACCAGTGCAAGAGGCGGCCACCGTCAAAGTAGCGGCCGAAGCACATCCACCTCCACCAATGCAAGAGCAACAACCGCCCGTTTTGCTCACACAGCTAAAGCAGGAACCGAATGTAGATCATCTAGAGGAGCATGCGATACCGGAAGTGGTGTCGGTGCAGCAACCCCCACCTCCGCTACCAGTACCGCCAACGCCACCCCAACATCGAGCACCCGCACCGACGCGCGTCATGACGAACGGCCGTGGTGGTGGTGGCACTACTACGCCTCAACAATTTACGACGACGGTCGAACCCACGGTGCCGCGTGTGGCGTCTCCATCGGCGGCAACGGAAGTCTCACCGAAAGAGACGGTGACGGCGCCCTCGCAAGTACAACAACCTGCCGTGAAGCGTGGTCGTGGACGTCCACGGAAATCGACATATCAATCACCGCAGGTGGCTGTCGCTGCTACAACTACAGAACTACCTTCCACCACCAGAGAACCAACCATCGCAACTGAACCGGTGGTCGAATCGCATGAGAAAGATAATGTGACTGTTAATGGAAGCGGTTCTACTGCCGCCAGTGAAGAAGTGGAAGTGAAGAAACCGAAAAAGAAAGGATACATTTCGGTGGTGGAACGGTTTGCACTTTCGAAAACAGAAAAGCAAAAATCGCAACAGGAGCGCGATGAACCGGAAGCAATGGACGTTGTTGTGCCTGCTGCACCCGAAACCCGAAACGAAGTGCCGGATATTTCGGTAGCAATCGAAACGGTTGCACCGACTGCACCACGGGGTGGAATCGAAACTAAGACTGAACAATTACTAGCTACCCCAATGGTAACGCCTGTTAAAGCGAGTGAAGCAACGGAAATTTCATCGGTAGAGATTAAGGTGCAACCAGGACCAATTTCTCCTCAGGTGCCGCTGGTTGTGCAGGAAGAGATGGCAGAGGAGCCGCAGCCGCAGCTCCAGCAGGATGAGGAGGTGGGTAAGAATCGTGAGGAAAGTGTGGTGAGCGCTGGAGATGGTGCTGAATCGTCGTCCTCCTCCTCGTCCTCCTCCACCTCCGTGGAGGACAGTGTAATCCTACCGAAGCAGCCGGAGGAGGTTTCGCTTGCACCGGACACGGAAAAGGAATCCTCTCCGGTGGCCAGTGACAGTGGGATCGAGTCGGTCAACGAAACCACCGTCGTTAGTACGGTGACCAAAAAACGATCCTCTGTTGGGCGTTCCAAATCGAGCCTGGCGGTTGTGAAGCCAGCGGAACAGGATGATAAGAAGCAGCAGCAGCAGCAGTCGGAGGAACAGGAGGATCTGAAGCCCGTCGTGGTGGGTCGTACGTCTACGGTGAAGCGTACCGTCCGCACGTCCCGTAAACCGTCCGCGAAAGCGAAAGAAGCGGCAGAAGCTGCTGAGGTGGCGGCACAAACGGTGGCTCTGACGAACGCTGGCAGCCCCGACGAATTTCAGTGTCCGAAGTGTGACATGTCGTTCAAGACTGAGCCGTGGTACAAGAAGCATCTCCTGAAGCACCATGATATAGAGCCCGAGGCTGGTGTTTCCTCACCGGAAGGAGCGAAGAAAGTGCCGGTAGAGGAAGTGAAACAAGATGACACCTCAACAAGGGTGGAGGAGGAGGTGGTAGTGCCGTCCCTACCGCCACCGCCACCACCGCAACCATCGGTCACCATTCCGTCCAAAGTGGAACCATCCACGTCGGGACGGAAGCGAAAGTCCACTTCCTCGACCGTTGATGAGCAGATCGGACCGAGCGTTACGAACGTGAAGCTCGAGTTCCGTGCCGGTGCCCAAAGTCGCACTGCCGAAACGTCGGAAGCGGAAGAAGAAGACGCTGGTGGCACCGTGGCGAAGGAGGAAAAGTTCGATCCGAACGATCCGGACAAACTGTCACCGTTCGAATCGGCCAAGGTGACGTGTAACGAACAGCAATACACCTGCACGATCTGTGGCGTACAGGTTACGGACATTCCGGCGATTAAAGAACATCTGGACACAGCTCACGCCGCCGTCAAGCGTCGCTCGTGTGAGTACTGTGGGCGTACGTTCGTGCAGACCGGTGATCTAACGCGCCACGTCCGAATCCATACGGGTCAGCGTCCGTTCAAGTGTCCCGTCGTGGAGTGTAGCTTCGCGTTCATCTCCTCCGGCGATCTGCACAAACACGTACGCCGACACAATCAGCAACCGCTTCCGAAACCGCACGTTTGCGATCAGTGCGGCAAGGACTTCGAGCGATCGTATGATCTGAAGCGCCACAAGACGATGCACGCCAAGAGTCAACCGAACTTTAAGGGCATTACGTGTGGTGTGTGCGGGAAGGAGTTTGCGAGACGCGATCAGTTCCGGGCGCACACGTACCGACACATCGGTTACCGGCCGCACCAGTGCGACATCTGCGGCAAAGCGTTTACCGATCCGAGCAACTTCTCCAAGCACGCCCGGCTTCACGAGATGGACGGCGTGCAGGTGGTGTGCCATTTCTGCGGCCGCCCGTTCAAGAACAAGAGCGCCATCTCGAAGCACATCTTCCACTGCAAGCAAAAGAAGGGTGGGAAGAAAGCAGACAGCAAGGAAGGCGGTGGTAAGGAGGACGGTGGACGAGGATCGAAGAAGAGTCGACGCGTTGGGGCGGCGGTAGGATACGGTTCGGGTGCGGACGGAGGGGACATAACGCCGGTGGTGAAGTCGGTGAAGCAGGAAGCGCTTGCCGAACAGCAGGATGCCGACGAGCTGGAGGACGTGCCGTCGGCTTCGGCCGCGGGATCTAGCAACGGAAAGCATCAGCAATCGCGGAAGCGCAAACGACGACGTCAACGGACCCCATCGTCTTCGGAGGAAGAGGAGGAGAACGACGACGAAGTGGAGGAAGAAGAGGATGAGGACGACGACCAGGTGAACGATGATAGTGGGGACGATTACGTTGGCCCACGTTCTTACCATTCCGGATCGGGTGCTAGTGTAAAGCGCGATCGGCGAAGCAGCAGAAAAAATGAACCAGTGGCTGCTGCTGAGGACGAGGACGACCAGGAGGAAGAGGAGATGGAGGAGGATGAAGTCGCGTGA
Protein Sequence: MSTLKARDTVRITHPEKLLIRTTVEPVAAVAAPSVATVLRSPTTPVQEAATVKVAAEAHPPPPMQEQQPPVLLTQLKQEPNVDHLEEHAIPEVVSVQQPPPPLPVPPTPPQHRAPAPTRVMTNGRGGGGTTTPQQFTTTVEPTVPRVASPSAATEVSPKETVTAPSQVQQPAVKRGRGRPRKSTYQSPQVAVAATTTELPSTTREPTIATEPVVESHEKDNVTVNGSGSTAASEEVEVKKPKKKGYISVVERFALSKTEKQKSQQERDEPEAMDVVVPAAPETRNEVPDISVAIETVAPTAPRGGIETKTEQLLATPMVTPVKASEATEISSVEIKVQPGPISPQVPLVVQEEMAEEPQPQLQQDEEVGKNREESVVSAGDGAESSSSSSSSSTSVEDSVILPKQPEEVSLAPDTEKESSPVASDSGIESVNETTVVSTVTKKRSSVGRSKSSLAVVKPAEQDDKKQQQQQSEEQEDLKPVVVGRTSTVKRTVRTSRKPSAKAKEAAEAAEVAAQTVALTNAGSPDEFQCPKCDMSFKTEPWYKKHLLKHHDIEPEAGVSSPEGAKKVPVEEVKQDDTSTRVEEEVVVPSLPPPPPPQPSVTIPSKVEPSTSGRKRKSTSSTVDEQIGPSVTNVKLEFRAGAQSRTAETSEAEEEDAGGTVAKEEKFDPNDPDKLSPFESAKVTCNEQQYTCTICGVQVTDIPAIKEHLDTAHAAVKRRSCEYCGRTFVQTGDLTRHVRIHTGQRPFKCPVVECSFAFISSGDLHKHVRRHNQQPLPKPHVCDQCGKDFERSYDLKRHKTMHAKSQPNFKGITCGVCGKEFARRDQFRAHTYRHIGYRPHQCDICGKAFTDPSNFSKHARLHEMDGVQVVCHFCGRPFKNKSAISKHIFHCKQKKGGKKADSKEGGGKEDGGRGSKKSRRVGAAVGYGSGADGGDITPVVKSVKQEALAEQQDADELEDVPSASAAGSSNGKHQQSRKRKRRRQRTPSSSEEEEENDDEVEEEEDEDDDQVNDDSGDDYVGPRSYHSGSGASVKRDRRSSRKNEPVAAAEDEDDQEEEEMEEDEVA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -