Basic Information

Insect: Anopheles farauti
Gene Symbol: prg
Assembly: GCA_000473445.2
Location: KI915043.1:12430391-12432446[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.041 2.4 8.3 0.5 1 23 243 266 243 266 0.87

2 10 0.037 2.2 8.5 0.4 3 23 274 295 272 295 0.95

3 10 0.00068 0.04 13.9 1.3 1 23 301 323 301 323 0.96

4 10 1.1e-08 6.4e-07 29.0 1.3 1 23 329 351 329 351 0.98

5 10 1.6e-05 0.00093 19.1 1.8 1 23 357 380 357 380 0.94

6 10 0.0042 0.25 11.4 0.4 1 21 387 407 387 408 0.93

7 10 0.00017 0.01 15.8 2.0 1 23 496 518 496 518 0.98

8 10 7e-05 0.0042 17.0 2.9 1 23 526 548 526 548 0.99

9 10 1.7e-05 0.001 18.9 2.9 1 23 554 576 554 576 0.97

10 10 1.2e-05 0.0007 19.5 0.1 1 23 583 605 583 605 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.041	2.4	8.3	0.5	1	23	243	266	243	266	0.87
2	10	0.037	2.2	8.5	0.4	3	23	274	295	272	295	0.95
3	10	0.00068	0.04	13.9	1.3	1	23	301	323	301	323	0.96
4	10	1.1e-08	6.4e-07	29.0	1.3	1	23	329	351	329	351	0.98
5	10	1.6e-05	0.00093	19.1	1.8	1	23	357	380	357	380	0.94
6	10	0.0042	0.25	11.4	0.4	1	21	387	407	387	408	0.93
7	10	0.00017	0.01	15.8	2.0	1	23	496	518	496	518	0.98
8	10	7e-05	0.0042	17.0	2.9	1	23	526	548	526	548	0.99
9	10	1.7e-05	0.001	18.9	2.9	1	23	554	576	554	576	0.97
10	10	1.2e-05	0.0007	19.5	0.1	1	23	583	605	583	605	0.98

Sequence Information

Coding Sequence: ATGAACATTGCCAATGGGACGGTTCCCGCGGCGGAACTACAACTTTGCCGGCTTTGTCTTGGCCGGGACGGAGTGCTGGTGAATATATTCGGAGTGCAGGAGGCTAGTGTGAGCGATGCAGAATCTTTAACCGCACGAATACGAGGCTGTCTGCAGCTGGAGGTAACGCAAACCGATACTCTTCCGAAGTGGATATGTAAGCTGTGTTTGGAGAAGATTGATGACTTCACAAACTTCCGGGAGCGATGCAAACAGAACGAACGGAAGCTGTTGCTAGGTAACGAAGATGAGCATATGAAGGATGGTAATATAGCCAACGACGATGGCAACAACGACCAAGAACCGACGGATGATGACGACGATGGAGAGGAGGATGAGGAGATGGAAATGATTGTAATCGATCCCACGCGAGACTACGAAAGTTCGGGCGATGAAAGTGGTCTTCCGGCGGAAGCGTATGTGGAAAAGAATGGTATTCCGAGCGTACAGCACGAGCAAAATCCTCCTGCCGACGATGACGACCACCAGGATGGTTCCGAAGCGGAAGAAGGAGAAGAGGAAGAAGAGGAAGAAGATGAGGACGATCTCAAATGTGATACGATGCCGGTGGAAGCACGAAACGGCGTACCACACACTGGTGCTGTTGATAGAATCAACAACAGCATCGCCACACCCAACAACATCTCCACCTCTTCATCGACTGGTACCCCGCAGAAAACGATCGTTTATACGTGCAAGTACTGTGATGTGGCGTTTGCGGCTTCTTCCGCCTGCCAAGTGCACGAAATGCAGGACCACGATCTGTTGGCACCGTACGGGTGTCCGTTCTGCCAATACAAAACCTCCATCCGGACGTATTTGATCACGCACATACGCGACCAGCACAGCATCACGCGGCCGTACATTTGCGTGCAGTGCAATAAGGGCTTTCTGCGCCGGTCGGATCTCAAGAAGCACACGTTCGTGCATACGGGCGTGCGGCCGTACGCGTGCGAACAGTGCGGGAAGAGCTTTTCGCGCAACACGAATCTCAAGAAGCACCTGCTTACGCACACGGGAATGAAGCCGCATGCGTGCGAAAACTGCGAGCGCTCGTTCGCCAACAAGGCGGACCTGGTGCGGCACATGATGCATCAACATCCGGAGCAACTGCAGCAGCATCCGTGCGTACGGTGTGGGACGGTGTACACGCAGAAGGACAAGCTGTACGAGCACGAACGTTACTGTTTGGGGCTTGTGGGAGGCGGCGGTGGTGGTGGTGTTGGTTCGTTTGCTGATGCGAAGCAGGAGCAGTCACCGTTTATGGGTGCATTAAGCGCACCAATCGAGGCGCAACCACCTCCACCGCAAATGTTTTCCGTTCCGGGAGTGGATACGATCAAAATAGAGCCTCCCGTAATCGAACCGCCAAGTTACGCCCCTATACCGCCATCACCGATCGTACCACAGATACCTCCATCGACTGCGCCTCCATCGAGCAAAATCTACGACTGCTCGAAGTGTCCCAAGCGTTTCCTCAGTAAGTTTAGCTTGCGGGCACACCAGAGCACCCACACGCCCGAGGACACCCGGATGTACGAGTGTCCACAGTGCGGCAAGCACTTGCCCGACAAGCGCACGTACGAGCACCATCTTCAGACGCACGTACCAATGAAACCGTTCGCTTGCGCGACGTGCGGCAAGCGATTCTCGCGCAAGGATAAAATGCACCGCCACGAGCGGGTCCACCAGCAGCCGGATCGACACTTTTCCTGCCCGAACTGTGCGGCCAAGTTCGTGCGGAAGGATGCACTAGAGACGCATATGAAAATACACTGCAGCGTGAATGCGGTTCCGCCGCCACTCATCGGTACTGCGGGTCTGTTTGCTTCGATTGGACATGGTGGGGCGGTTGGACAGATGCCACAACAACATTCCCTGCTGTATTCGATGGTCGGCGCGAACGATGGAACGGTCGGGATCGATCCATCAATTCGGATGTAA
Protein Sequence: MNIANGTVPAAELQLCRLCLGRDGVLVNIFGVQEASVSDAESLTARIRGCLQLEVTQTDTLPKWICKLCLEKIDDFTNFRERCKQNERKLLLGNEDEHMKDGNIANDDGNNDQEPTDDDDDGEEDEEMEMIVIDPTRDYESSGDESGLPAEAYVEKNGIPSVQHEQNPPADDDDHQDGSEAEEGEEEEEEEDEDDLKCDTMPVEARNGVPHTGAVDRINNSIATPNNISTSSSTGTPQKTIVYTCKYCDVAFAASSACQVHEMQDHDLLAPYGCPFCQYKTSIRTYLITHIRDQHSITRPYICVQCNKGFLRRSDLKKHTFVHTGVRPYACEQCGKSFSRNTNLKKHLLTHTGMKPHACENCERSFANKADLVRHMMHQHPEQLQQHPCVRCGTVYTQKDKLYEHERYCLGLVGGGGGGGVGSFADAKQEQSPFMGALSAPIEAQPPPPQMFSVPGVDTIKIEPPVIEPPSYAPIPPSPIVPQIPPSTAPPSSKIYDCSKCPKRFLSKFSLRAHQSTHTPEDTRMYECPQCGKHLPDKRTYEHHLQTHVPMKPFACATCGKRFSRKDKMHRHERVHQQPDRHFSCPNCAAKFVRKDALETHMKIHCSVNAVPPPLIGTAGLFASIGHGGAVGQMPQQHSLLYSMVGANDGTVGIDPSIRM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00103149;
90% Identity: iTF_00103149;
80% Identity: -