Afar011739.1


Basic Information
Transcription Factor Domain
Sequence Information
Similar Transcription Factors

Basic Information

Insect
Anopheles farauti
Gene Symbol
ZFY_1
Assembly
GCA_000473445.2
Location
KI915040.1:17790477-17797160[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 25 0.012 0.69 10.1 5.0 2 23 396 417 395 417 0.97
2 25 0.014 0.84 9.8 5.0 2 23 424 445 423 445 0.98
3 25 0.0055 0.32 11.1 0.8 1 23 455 477 455 477 0.96
4 25 5.5 3.3e+02 1.6 1.9 2 23 486 507 485 507 0.88
5 25 1.5 86 3.4 0.4 1 23 513 533 513 533 0.85
6 25 9.7e-05 0.0057 16.6 0.2 1 20 545 564 545 565 0.97
7 25 0.0036 0.21 11.7 1.0 2 23 574 595 573 595 0.97
8 25 2.1e-05 0.0012 18.7 0.9 2 23 601 622 600 622 0.93
9 25 0.063 3.7 7.7 3.0 2 23 631 652 630 652 0.95
10 25 4.4e-05 0.0026 17.7 1.9 2 21 659 678 658 679 0.94
11 25 0.0015 0.087 12.9 3.1 1 23 690 712 690 712 0.98
12 25 0.00077 0.045 13.8 2.5 1 23 718 741 718 741 0.98
13 25 8.5 5e+02 1.0 0.8 1 15 769 783 769 786 0.80
14 25 0.00058 0.034 14.2 3.4 2 23 1125 1146 1124 1146 0.97
15 25 0.048 2.8 8.1 4.3 2 23 1153 1174 1152 1174 0.97
16 25 0.095 5.6 7.2 1.6 1 23 1184 1206 1184 1206 0.96
17 25 1.7 98 3.3 0.0 3 23 1231 1258 1230 1258 0.81
18 25 0.53 31 4.8 0.1 2 23 1265 1286 1264 1286 0.95
19 25 0.0001 0.0061 16.5 0.2 1 20 1324 1343 1324 1344 0.97
20 25 0.0086 0.51 10.5 1.4 2 23 1353 1374 1352 1374 0.95
21 25 0.00032 0.019 15.0 1.0 2 23 1380 1401 1379 1401 0.92
22 25 0.26 16 5.8 2.8 2 23 1410 1431 1409 1431 0.97
23 25 1.9e-05 0.0011 18.8 1.7 3 21 1439 1457 1437 1458 0.95
24 25 8.2e-05 0.0048 16.8 2.0 1 23 1469 1491 1469 1491 0.99
25 25 0.00077 0.045 13.8 2.5 1 23 1497 1520 1497 1520 0.98

Sequence Information

Coding Sequence
ATGGCAGACAAAAAGCAGTGTACGCTTTGCTTATGCACTGACTCCAATTGGTTTCTGGAGGTGTTTAATGATGACAATAGAATGCTTGATATTGCGGATATCGTATCGAAACATCTGTGGTTTGATCTAAAACCATCCACCCAACCGAACATTTGTTCCGAATGCTGGACAAGTGTGCATGATTTTCACCTGTTCTACACCAAGCTTGAGAGTGTTCATAATCAGGATTTGCTGGATGTAAACTCAATCGCCGAATGTGCATTGTCCGACGTTAAGAACGTGCAACTCGTTCACGAACATCAGGATGATCGTCTTCAACCAGCAGAGCATGACGCCGAAAACCAATCGGATGATAGTGAAACGAATGCAGGAAATCAAAGTGCAACGAATGCTTCCGATACGAAAACCACCGATAAAAAACATTTCGTTGTGGTGGACGAATATGACGAGAATGATGATGATTACTTTGATGAGTGTAACCGTGCGGACGATGATTATCTTGCCAACTCGCCGAAAACTGAAGTAATTGTACTTTCGGAAATGCCTGCAAAGCGTGGCAGGGGACGTCCACCGAAACGAAAACCGGAACAGCAAACAACCCTTCAAACGGCTGGTAATATATCTTCTACGGAGCATGTGCTCGAAGCACGAATGAATGATTCCCAAACAAACACACTGGACCAGCCTGTCAAGCGCCGCCGGGGAAGACCTCCGAAAATTAAACCAGAAGTCACACCCATGGAACGGAACGATGGGTCAACGACAAAGCAGGAAACGGACGTACAAGAATGTGTCACAACATCAACATCGCGTGAAACCCCAGCATCTGATCAAGCTCAACCGATCAAGCGAGGTAGAGGTCGCCCTCCGAAAATAAAGTCTGAAAACGGGTTCCAAACGGTGTCGGCAACCAAACTTTCCGCCGTACGCAAACGGAAGTCGACACTGGTGCGAAGGGATAGAAGCAGCAGCTCTAGCGCGCAAGATGACGATCCCGACTTTGATGGGATGCGGGTTAAAAAGAAAACATCGGAACAGAAAAAGGTCCGCAACGACCGGGACGAGCGAATCTTCCAACACGTAACCGATTTTTCCTGTGAGTACTGTGTGGACAAGGTGTTTTTCAAGCGTTTCATTGATGCGGACCGACACTACAAGCTGGTGCATAACGAGCCCGGCTTTTTGAAGTGTCCAAAGTGTGATAAAAAATGTCACACAACCGGCATGTTCCTTAGCCACATGGAAACGCATGAAGATCCGGACAAGAACAAGTGTCATATATGCGGCAAGCAAACGGATTGTAATATTTCACTGAAAAAGCATATGCGCATCCATCAGAGCCAGCTAGACCAGGACCTACCGTTCCCGTGCAGCATTTGCAAGCGAAAGTTTGAATCGGAGGAGCAGCGTATCAAGCACGAAAAGTTACACGAGCATAACAAAGGTGCGTACCTGAAGTGCCCACTGTGTTCCAAGCGACACCTCTACCGGCAGCACCTCATCGCTCACATTGACGTACACAACAACCCAGAAAAGTATCGGTGCGAAGTGTGCAAAGAAATCTACCAGAATCTGGATCAGCACATGATTAAAGCGCACACACCCCACACATCGTCAGCGTCGGACAAAAAGTACAAGTGCGATCAGTGTGGGCGAATGTTTAACTTTTTAGCGAATTTGAAGATGCACATCGATTGCATTCACGGCTCGAAGGATATTCGGTGCAATATCTGCAATAAATACTTTAATCTTAAAGCCTTCCAAGTGCACAAGCGAACGGCACACACGGACCAGATGCTGATGTGTGAACACTGCCCGAAGATGTTTAAGACACGTAGCGCACTGGAAGCACACAAGAGCGCCCACGACGATAGCTTGGTACAGTTTACGACGTGTAAGTTCTGCAACAAACAGCTCCGGTTGTCCAACGTCAAGAAGCATATGAAAAATCTACACTCCGAGGAAGGGCCGTCCAGCTGTGAGCTGTGCGGCAAAACGTTCCGCAGTCCATTCCACATGAAGCGACATCAGAAAAATTCCTGCGAAGCGACAATTAATATGCGCAAGCACAAGTGCGAGATATGCGGCAAGGGCTTCTGCCTGAAGTTGACGATGATCGAGCACATGACGACGCATACGCGCGCAAACCAGTATCAGTGTGCGTTTTGCTTCAAATCGTTCGGATATATCTCGAATCTGTACAAGCACCGCAAAAAGGCACATCCGCTCGAGTGGCAAGAGGTGCAGGCGAGGCCAGAGGAGGGCATTGCGACGGTAATCGTCCTCAAACCATCATTGCACCCGTACGTTTGTACTGATTGTTGGACAAGTGTGTATGACTTTCATCAATTCTACACAAGACTTGAAAACGTATATAACCAGGGACAGGTTGGCGCCGAAATGGTCGAAGTATTGGACATCGAGTTTCTGGATGAGGATGCTGAGGAACTTCGCTTTCAGATAAGGCATACACCCAAGATCAAGGATAACGACGACCTTGCCAGACCAAATGTACATCCAGACAAGAAACAAAGTATAGGTCCAGATGATGAGGAATATATTTCAGGGGAAGAAAATTATGATTACGAAAATAATGATTACGATAACGATTCCCTCGAACACGACGAAAGCGCTGATACATCGTACGTGGAGGATGAAAAGAAATCCGATAAAATTGGGCAACGGTCTACAATCGCTATCGATATTATGGATGCTCAAGAGCAGCCAGTAAAACGGCGTCGTGGTCGTCCACCGAAGCGTAAGCTACCGGAAGATGAGGTACAAACTTCTAGTGTGGAAAAAAAGAAACAAAATCTGAACGCAACCCGAGCCTCATCCATCGTGTCATCCGCGGACCAACCGGTAAAGCGTGGTCGTGGTAGACCACCGAAGCAGAAACCGCTGGACGCTGGTGACGTTCCGGCATCAGCAGCTCATACACCAACCATAAAGAAGGAGATAAAATCGGAGTTTGGTGACAGTAGCGATAAAGATGCAACACCGAACTCGTCGAAGTCAGGAGTACAACCCGAACGTAGATCGACCCGTGTTCGGAAGGTAAAGTATCTGAGTGAAACCGAAGTGGATACCGCGGAAGACGAAGAAAGCGAACTGAACGAGAGTGACATGGAGGAATGCGATGATCCGGAGTACGAGGAAAAGCTGGAATTGCAAAGGAAACTGAACATGGACGATTATGAGTTCTACGAGTATCAGTGTAACATGGAATCGGAGCAGTTTGCGCGCGATAACAGGATATTTCAGTACGTGGATGAGTTTATTTGCCACTATTGTGTGGAAAAGGTGCATTTCAAGCGGTTTGCCGAGGCGGACGTGCATTATCGAGTGGAGCATAAGCAGCCCCCGTTCCTGAAGTGCCCAAAGTGTGATAAGAAATGTCACAATCCAGGCATGTTCATCAGCCATATGGAAACGCACGACGATCCGGAAAAATCTAGGTGCCACATTTGCGGCAAGCTAACCGATTGTAACATTTCGCTGAAGAAGCATATGCGCGTACATCAAGGAAAGCTTGAGCAGAACCTGCCTTATCCATGCAGTCGCTGCAAGCGCAAGTTCGAGACCGAAGAGCAGCGCGACAAGCACGAGAAGCTACACGTACCGAAGCCGTTTGTACCGCGCGACGAAGGTCCTGATCTGGAGGTGCTCGAGTTCTACAAGCGGATCTTCTGCGACATATGCGAGGAGGGCGAACCGGAATCGACCTCGTTCGACAACCTGTGGGCTCTGCGAACGCACATGGCTAACGAGCACCGGAAGAGCTTGTTCGTCCGGTGCCCCGTGTGCTTCAAGCGGCAGATCAATCGTACCCAAGTCATCGCTCACATTGACATGCACAAAAATCCGGACAAGTATCGATGTGAAGTTTGCCAGGAAGTTCATCAGGATCTGCCGCGACACATGATGAAGACGCACACACCCAACACGAAGGAACAGGTGGAGAAAAAGTACGAATGTGAGCAGTGCGGGCGAATGTTCAACTACTTGACCAACTTAAAAATGCACATCGATTGCATTCACGGTTTAAAGGATGTTCGATGTAACATTTGCGACAAGTACTTCAACTATAAGGCGTACCAAACGCACAAGCGTAAGGCACACACCGACCAAATGCTGATGTGCGAACACTGTCCGCGGATGTTCAAGAATCGCAAAGCGTTGGAAGCTCATAAGGGCTACCACGACGCGAGTCTGCTGAAGCTTACGAAATGTGATCTGTGCGGGAAACAGATACGCGCCTGCAGCATGTCGAAACACATGAAAACGATGCATTCGGAGGAGGATCCGATCGACTGCGAGCTGTGTGGCAAAACGTTCCGTACCTCGTTCCACATGAAGCGGCATCAGCGCAACACGTGTGAGGCGACGATGGATTCGCGCACGTTCAAGTGCGAGGTGTGCGGTAAGGGATTCTGCACAAAGCTGACGATGGTTGAGCACATGACGACACATACGCGCGCGAACCAGTACCAGTGCGCGTTCTGCTTTAAATCGTTCGGATACATCTCGAATTTGTACAAGCACCGCAAAAAGGCACATCCGCTCGAGTGGCAAGAGGTACAGCAGCACCCCGAGGAAGGAATAGCTACCGTGATCGTTGTGAAAAATTGA
Protein Sequence
MADKKQCTLCLCTDSNWFLEVFNDDNRMLDIADIVSKHLWFDLKPSTQPNICSECWTSVHDFHLFYTKLESVHNQDLLDVNSIAECALSDVKNVQLVHEHQDDRLQPAEHDAENQSDDSETNAGNQSATNASDTKTTDKKHFVVVDEYDENDDDYFDECNRADDDYLANSPKTEVIVLSEMPAKRGRGRPPKRKPEQQTTLQTAGNISSTEHVLEARMNDSQTNTLDQPVKRRRGRPPKIKPEVTPMERNDGSTTKQETDVQECVTTSTSRETPASDQAQPIKRGRGRPPKIKSENGFQTVSATKLSAVRKRKSTLVRRDRSSSSSAQDDDPDFDGMRVKKKTSEQKKVRNDRDERIFQHVTDFSCEYCVDKVFFKRFIDADRHYKLVHNEPGFLKCPKCDKKCHTTGMFLSHMETHEDPDKNKCHICGKQTDCNISLKKHMRIHQSQLDQDLPFPCSICKRKFESEEQRIKHEKLHEHNKGAYLKCPLCSKRHLYRQHLIAHIDVHNNPEKYRCEVCKEIYQNLDQHMIKAHTPHTSSASDKKYKCDQCGRMFNFLANLKMHIDCIHGSKDIRCNICNKYFNLKAFQVHKRTAHTDQMLMCEHCPKMFKTRSALEAHKSAHDDSLVQFTTCKFCNKQLRLSNVKKHMKNLHSEEGPSSCELCGKTFRSPFHMKRHQKNSCEATINMRKHKCEICGKGFCLKLTMIEHMTTHTRANQYQCAFCFKSFGYISNLYKHRKKAHPLEWQEVQARPEEGIATVIVLKPSLHPYVCTDCWTSVYDFHQFYTRLENVYNQGQVGAEMVEVLDIEFLDEDAEELRFQIRHTPKIKDNDDLARPNVHPDKKQSIGPDDEEYISGEENYDYENNDYDNDSLEHDESADTSYVEDEKKSDKIGQRSTIAIDIMDAQEQPVKRRRGRPPKRKLPEDEVQTSSVEKKKQNLNATRASSIVSSADQPVKRGRGRPPKQKPLDAGDVPASAAHTPTIKKEIKSEFGDSSDKDATPNSSKSGVQPERRSTRVRKVKYLSETEVDTAEDEESELNESDMEECDDPEYEEKLELQRKLNMDDYEFYEYQCNMESEQFARDNRIFQYVDEFICHYCVEKVHFKRFAEADVHYRVEHKQPPFLKCPKCDKKCHNPGMFISHMETHDDPEKSRCHICGKLTDCNISLKKHMRVHQGKLEQNLPYPCSRCKRKFETEEQRDKHEKLHVPKPFVPRDEGPDLEVLEFYKRIFCDICEEGEPESTSFDNLWALRTHMANEHRKSLFVRCPVCFKRQINRTQVIAHIDMHKNPDKYRCEVCQEVHQDLPRHMMKTHTPNTKEQVEKKYECEQCGRMFNYLTNLKMHIDCIHGLKDVRCNICDKYFNYKAYQTHKRKAHTDQMLMCEHCPRMFKNRKALEAHKGYHDASLLKLTKCDLCGKQIRACSMSKHMKTMHSEEDPIDCELCGKTFRTSFHMKRHQRNTCEATMDSRTFKCEVCGKGFCTKLTMVEHMTTHTRANQYQCAFCFKSFGYISNLYKHRKKAHPLEWQEVQQHPEEGIATVIVVKN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-