Basic Information

Insect: Anopheles farauti
Gene Symbol: -
Assembly: GCA_000473445.2
Location: KI915045.1:8232727-8237922[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 5.5e-07 3.2e-05 23.7 3.3 1 23 192 214 192 214 0.98

2 10 3.4e-08 2e-06 27.5 1.2 1 23 220 242 220 242 0.98

3 10 1.8e-05 0.0011 18.9 1.4 1 23 248 270 248 270 0.99

4 10 0.012 0.69 10.0 0.9 1 23 276 299 276 299 0.95

5 10 0.0016 0.097 12.7 1.5 1 23 474 496 474 496 0.98

6 10 0.0026 0.16 12.1 1.7 1 23 600 622 600 622 0.96

7 10 0.023 1.3 9.1 0.4 2 21 671 690 671 692 0.95

8 10 4e-08 2.4e-06 27.2 1.8 1 23 709 731 709 731 0.99

9 10 5.4e-05 0.0032 17.4 1.2 1 23 737 759 737 759 0.98

10 10 0.0014 0.08 13.0 0.4 1 22 765 786 765 786 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	5.5e-07	3.2e-05	23.7	3.3	1	23	192	214	192	214	0.98
2	10	3.4e-08	2e-06	27.5	1.2	1	23	220	242	220	242	0.98
3	10	1.8e-05	0.0011	18.9	1.4	1	23	248	270	248	270	0.99
4	10	0.012	0.69	10.0	0.9	1	23	276	299	276	299	0.95
5	10	0.0016	0.097	12.7	1.5	1	23	474	496	474	496	0.98
6	10	0.0026	0.16	12.1	1.7	1	23	600	622	600	622	0.96
7	10	0.023	1.3	9.1	0.4	2	21	671	690	671	692	0.95
8	10	4e-08	2.4e-06	27.2	1.8	1	23	709	731	709	731	0.99
9	10	5.4e-05	0.0032	17.4	1.2	1	23	737	759	737	759	0.98
10	10	0.0014	0.08	13.0	0.4	1	22	765	786	765	786	0.96

Sequence Information

Coding Sequence: ATGGTGAAGGAAATGCCGTCGAGCACGGTGGTCAACCGCGACGAGGAGTGTCTGAGAAAGTCCTTAATGGAGGTTGTGAAGAGCGATTCGAGCAACTTATGCCGACTGTGTTTGTCGAAGGAACAAAAGCTAACACGCGCCTTCGCAGACGAACGCGGCATTGATGATGCACTGTTGAAGAAAATCTTTGACTGTACCACAGTAAAGGTGAAATTAAAGGCCATCTTCCCGTCCGCTATCTGTGCGGTGTGCGACTTGAAGCTAAACGAATTCTACAAGTTCCGCCAGAAATGCATCGAAAACGACACCTTTCTTCACAGTTTGCTAGACGAACGGTTGGCGGTGCCGGAAGTCGATCAGTCCGTACCAACCGTCATCGATAGACGGCCGAGCCGAGCGTCGGAATGTGGCGGAACGCAACAACACGACTTGCCGACACCATCGCATCTGTCCACGATCGCGCACGTCGAGCAGAAGAAACGACAAATGGAGCAGGAACGTTCATTCGCGATGGCGGCACTGGAAATGGCGGGCCTACAAACGTTACGCACCAACACCGAACCGGGTGGCAAGTTCGAGTGCACCATATGCCACCGCATGTTCCGCAACGCGTACACACTCCGGCGGCACATGAATCTGCACACGGAAACGAATCTATTCCCGTGTGAGTACTGCGGTAAAAAGTTTAACGATCGCTCCAACTGGAAGATCCACCAGCGGACGCACACCGGCGACAATCTGTACACCTGTCTGGTATGCCTCAAGACGTTCATCTCACCGTCGACGCTAAAGTACCACCGGCGTTCGCACCGGCGGCTCGAATCGTTCGACTGTCGACTCTGTCCGTGCACGTTCGGCAGCTACGATCTGCTGGAGGAGCACGCGCGCAACTCGCACCAGGATATGCGAGACTTCCAGTCGGCGGAGGAGCCGATGATCGACGCGGCCAGCTTCGTGAAGATCGAGCTCGAGGACGAGGGTGACCTGTCGAGTTCGACGGCGGTGGGTGATGTGTCTACTACGCAACAGCACCCGCCGGTAAAGGGGATTGACGAGGAGGAGGATCGGGACCGACGGCGGACGGTCGTGGATAGCAGCAGTGTCGTGGACGAGATGCAGCTGGCGGAGCTGTACCGAGCGCAGCAGGAAATTTTGGAACTGTTGGAAAAAGATCTGCAGGCGGGGGTTATACGAGCAACAGGAGGAGGAGAAGGAGCAGCAGGAAGTACAAGAGATAATGCAATCGGTGTACAAACGCGGGATGTGGCGGCCGATGACAAAGTAGAGTCGATGGAACTGGATCCAAGTGAACTGTTGCAGCAGGCAATGGAGGAAGCGGCGGACGATGGTGATGAAGCGGAAGCTGGGGACGACAAGCAGGCTTCATCGTCCAGCTCATCGCCCTCGACGGTGATACTGTTTCGGTGTGATTACTGTATGAAAATATTCCATTTCCTGGATGAGCTGAACGCCCACATGCTCCTGCACAATGGAGCCAAAGGTGCCGCCGCCGGTGGTGGAGCGATAATGCTCGGTACGGCGGCGACCGGTCCAGGTGACCATGACGGTGGTACCGCCATGCCGTTGCTAGCGTTGATGCGATCCACCGGAGCGGTCAACAGTGCCATTCCCCTACCATCGAACGGTGCCGTAGCAGGTTCGAAGGGTAAACTATCGCGGAAACCGAAACGAAGGCGCACGGCTTCCGATTTCATGCCGATCCAGGCGAAACAGGTGCGACAGGGCGAGGCAGACGTAGCGCAGACAGAGATGCGAACGCTTCCCGCACCTCCAGAGCATCCCTGTTCCAAGTGCAGCAAGGTGTTCCGGACGGAGGAGTTGAAGCGTGTGCACGAGGAAACGCACGCAAATGACGAACAGACGAACAAGGAAAGCGATGACGAGGAATCGCCTGCTAATCGAATGCCGGACGCTGTTGCTTCACCGGAGGCAGCGCCGGAAGTTGCTTCACCCAGCTCCACCGCACTCAACCGGACCGCCGCGTTCCGGAAGTGCGAAATCTGTGCCATCGCTTTCGAGGACTCGGTATCGCTCGACAAGCACATGCTGTGCCATTTCGAGCGTAAGGAGGCAATCGCATTCGTACCCCAAACGGATCGCCCATTCCAGTGCACCGAGTGTGAGAAGAGCTTCAAGCGGAAGGACTATCTGTTGATACATATCCGCACGCATACCGGCGAACGTCGGTACAAGTGTGATCTCTGCTCGAGCGCCTTTGTGCATCCGTCGAATCTAATCACGCACCGGAAGCTTCACTCGAGCGAACGGCCTTACCAGTGCACCCTGTGCGGTTCCACGTTCAAGCTGTACGCCGGGCTCAAGATCCATCGGAGGCGGTGCGAGCAAAAGCTACCGAAGAACTGGCCGGAAGGACTACTGGCGACTACGACGAGTTACGGTGCAGCTGGTGGCAGCGCTGATGGTGGTGGTGGTGGCAATAGTGTGCACGATCTGCACGCAGACGATAGTGGTACGCCGATGGCGAACTGCAATGTGTCCTATCCATTCTAA
Protein Sequence: MVKEMPSSTVVNRDEECLRKSLMEVVKSDSSNLCRLCLSKEQKLTRAFADERGIDDALLKKIFDCTTVKVKLKAIFPSAICAVCDLKLNEFYKFRQKCIENDTFLHSLLDERLAVPEVDQSVPTVIDRRPSRASECGGTQQHDLPTPSHLSTIAHVEQKKRQMEQERSFAMAALEMAGLQTLRTNTEPGGKFECTICHRMFRNAYTLRRHMNLHTETNLFPCEYCGKKFNDRSNWKIHQRTHTGDNLYTCLVCLKTFISPSTLKYHRRSHRRLESFDCRLCPCTFGSYDLLEEHARNSHQDMRDFQSAEEPMIDAASFVKIELEDEGDLSSSTAVGDVSTTQQHPPVKGIDEEEDRDRRRTVVDSSSVVDEMQLAELYRAQQEILELLEKDLQAGVIRATGGGEGAAGSTRDNAIGVQTRDVAADDKVESMELDPSELLQQAMEEAADDGDEAEAGDDKQASSSSSSPSTVILFRCDYCMKIFHFLDELNAHMLLHNGAKGAAAGGGAIMLGTAATGPGDHDGGTAMPLLALMRSTGAVNSAIPLPSNGAVAGSKGKLSRKPKRRRTASDFMPIQAKQVRQGEADVAQTEMRTLPAPPEHPCSKCSKVFRTEELKRVHEETHANDEQTNKESDDEESPANRMPDAVASPEAAPEVASPSSTALNRTAAFRKCEICAIAFEDSVSLDKHMLCHFERKEAIAFVPQTDRPFQCTECEKSFKRKDYLLIHIRTHTGERRYKCDLCSSAFVHPSNLITHRKLHSSERPYQCTLCGSTFKLYAGLKIHRRRCEQKLPKNWPEGLLATTTSYGAAGGSADGGGGGNSVHDLHADDSGTPMANCNVSYPF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -