Basic Information

Insect: Anopheles farauti
Gene Symbol: -
Assembly: GCA_000473445.2
Location: KI915041.1:13350927-13353338[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 2.8e-06 0.00016 21.4 0.6 1 23 342 364 342 364 0.97

2 9 3.8e-07 2.2e-05 24.2 0.4 1 23 370 392 370 392 0.97

3 9 7.7e-05 0.0046 16.9 1.7 1 23 401 423 401 423 0.98

4 9 0.0019 0.11 12.5 1.3 1 23 429 452 429 452 0.95

5 9 8.4e-06 0.00049 19.9 0.4 1 23 489 512 489 512 0.98

6 9 7.6e-06 0.00045 20.1 1.4 1 23 516 538 516 538 0.93

7 9 7e-05 0.0042 17.0 3.7 1 23 544 567 544 567 0.97

8 9 1.6e-06 9.3e-05 22.2 0.2 1 23 607 629 607 629 0.96

9 9 0.021 1.3 9.2 0.1 1 20 638 657 638 661 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	2.8e-06	0.00016	21.4	0.6	1	23	342	364	342	364	0.97
2	9	3.8e-07	2.2e-05	24.2	0.4	1	23	370	392	370	392	0.97
3	9	7.7e-05	0.0046	16.9	1.7	1	23	401	423	401	423	0.98
4	9	0.0019	0.11	12.5	1.3	1	23	429	452	429	452	0.95
5	9	8.4e-06	0.00049	19.9	0.4	1	23	489	512	489	512	0.98
6	9	7.6e-06	0.00045	20.1	1.4	1	23	516	538	516	538	0.93
7	9	7e-05	0.0042	17.0	3.7	1	23	544	567	544	567	0.97
8	9	1.6e-06	9.3e-05	22.2	0.2	1	23	607	629	607	629	0.96
9	9	0.021	1.3	9.2	0.1	1	20	638	657	638	661	0.93

Sequence Information

Coding Sequence: ATGAAGTGCCTAGTGCCCGGTTGCGATACGGATGATGACGTCGTGAGCTACACATCGGTGTTTTTCGTGAAATTCCCAAGCGAACCGAGAGTGCAGCAGCAATGGTTTTCCCAGTTGGAGATATCCGATTCCCTGCTCATGCAGTCTTTGGTGCGAGGAGAATCCAAAGTTTGCAGTTGCCACTTTGCCGACGATTGCTTCGGACACCATCCGGTGTACGGGTATCGTTTCCTGCTGCCCAAAGCCTTGCCAACCATTATTCCGAAAGAACCGAAGAAGAAAGTAGATCCAGTGGATGCGGTGGAGGATGATTCCTCACTGGACATTTGCTACGTGTACCTTAACGATTCGTTGAAGCCGGAAAGGAACGGATCCGTGATCCCCGTGGATGCTCCAAGCGAATCGGAGCTGAATGATGAAACAGAAGCAATGGAGGATGAAGAGGTGGCCGAAGAAGTAGACGACGATGAAGCGGTCGAAGAAATCGGCATCGAGTACGCGAATGGAAAGTACTACTTTCTCAAGCTGACCGATGATCCAACTGATGCTGATGCGCCGGAAACAAGTGCAATCCAAGCGAGCAGCGTTGAAAGTATCGAAAACGATACGATAAATGCATCCGAGGATGAAGCTAGTGCTTGCGACGACAGTAGGAGCGATGAAATCATCAACGAACCAGCTGCGTTCTTGAATGAAAAACCATTGGCGGGTGAAACTTCACCGTACTTCGGCGATAGGTGTTTGGATGAACCGGCTGAAAACAGCAGCGAGGAAAGGATAGATGAAGACATTCAATCGAACCATGATCTCCAACCAAAAGCTGTTGACGGCGAACGGCAGTCGGAGACAGAGGAACCGATCGAAGAGTATCTCGAAGACAGTGATACTGTTACAAGCGAGCACAACTTTCAGATAGAACGTGACGATCGGGTTGAAGATGGGGGTCACATCGAAACACTGGATGGGGTGTCTATTAGTTTCAGTAGTGAATGCTTGAAGGCGAAAAAGAAACATGAACATCGTTTCTTCTGCAAGGAGTGCGGTAAAGGGTTTCCATTTAAGAGCCAGTTGGATCGCCACCTCCTCGTACACACGAAGGAGAAGAAATTCTTCTGTGAAGTATGCGAAAAAGGCTTTTCGCAGAAGATCAATTTGACCATCCACATGCGCGTTCATACCGGCGAACAACCGGACAAGCGGTACACGTGCCAAATCTGCAACAAGAAGTGCTACCGGATAAGCGAACTGGAGGTGCACCTGGCCAGACACAAAAAACAGTTTCCCCACGTGTGTCCCGTCTGCACGCAGCGCTACTCGGACTTGACCAGCCTGTACAATCACTTCCGGGCGAACCATCGGGACGTGATGAACGAGCCGGAACTGATCGAACTGCTGGCACAAAGCGAGAATGCTATCGTCATTTCCGACCAGGAACCGACCGACATACGCCACACCGACGGACGGTACGAGTGTGCCGTCTGCGGTAAAGCGTTCCGACTGCAGCAGATGCTCGCTCGGCACAAACGAAAAATGCACATCAAAATCTACCGCTGCCCGCACTGTCCGCGCAAGTTTGCGTACAAAAGCCTGCTGGCCAAGCATCTGCCGACGCACACGCTGGAAAAGCCGTACCACTGTGCGCACTGTTCGCTGGCGTACACGCAGCGCGTCAATCTACAGGTGCACATGCGACGGAAGCACCCGCAGGTAGTGAACGACCAGGCCATAAAAAAGGTGGCCATAAGCAAGGTGGCGAACGAGCCGGAAAGTCAACAGTCCGAACAGAACGACGAGGACGAGGAGGAAGTCGTGCAAGCGTACGAGTGTGAACAGTGTGGGAAGCGATTCTCGCGAAAGCCGACGCTGTTGGCGCATCTCGAGGGACACGCGAACGGAACCGCACCGAGGACGTACGATTGCGAGCAGTGCGGTCTGTCGCTGTCCGGACTAACGGCCCTGCAGCGCCATCGGTGGCGGTTGCACGGGGCACAGACTAGCCAGACGAAGATGATCTCCAGTTTGGATCTCCGGAACGTGACGATAGTACCGACGGACAACGATTACTACGTGGAGATCGAAGATGAGATGGAAACCATTCACGAGGATTACGGGAATGAGGATTAA
Protein Sequence: MKCLVPGCDTDDDVVSYTSVFFVKFPSEPRVQQQWFSQLEISDSLLMQSLVRGESKVCSCHFADDCFGHHPVYGYRFLLPKALPTIIPKEPKKKVDPVDAVEDDSSLDICYVYLNDSLKPERNGSVIPVDAPSESELNDETEAMEDEEVAEEVDDDEAVEEIGIEYANGKYYFLKLTDDPTDADAPETSAIQASSVESIENDTINASEDEASACDDSRSDEIINEPAAFLNEKPLAGETSPYFGDRCLDEPAENSSEERIDEDIQSNHDLQPKAVDGERQSETEEPIEEYLEDSDTVTSEHNFQIERDDRVEDGGHIETLDGVSISFSSECLKAKKKHEHRFFCKECGKGFPFKSQLDRHLLVHTKEKKFFCEVCEKGFSQKINLTIHMRVHTGEQPDKRYTCQICNKKCYRISELEVHLARHKKQFPHVCPVCTQRYSDLTSLYNHFRANHRDVMNEPELIELLAQSENAIVISDQEPTDIRHTDGRYECAVCGKAFRLQQMLARHKRKMHIKIYRCPHCPRKFAYKSLLAKHLPTHTLEKPYHCAHCSLAYTQRVNLQVHMRRKHPQVVNDQAIKKVAISKVANEPESQQSEQNDEDEEEVVQAYECEQCGKRFSRKPTLLAHLEGHANGTAPRTYDCEQCGLSLSGLTALQRHRWRLHGAQTSQTKMISSLDLRNVTIVPTDNDYYVEIEDEMETIHEDYGNED

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00103051;
90% Identity: iTF_00103051;
80% Identity: iTF_00100356;