Basic Information

Insect: Anopheles farauti
Gene Symbol: Znf516
Assembly: GCA_000473445.2
Location: KI915059.1:387439-389886[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.045 2.6 8.2 2.7 2 23 120 141 119 141 0.96

2 16 1.7e-05 0.001 19.0 1.2 1 23 162 184 162 184 0.98

3 16 0.0003 0.018 15.0 4.9 1 23 195 217 195 217 0.96

4 16 4e-06 0.00023 21.0 0.6 1 23 226 248 226 248 0.98

5 16 3.8e-06 0.00022 21.0 2.6 1 23 254 276 254 276 0.98

6 16 0.0057 0.34 11.0 0.1 2 23 284 305 283 305 0.97

7 16 6.3e-05 0.0037 17.2 3.4 1 23 311 334 311 334 0.94

8 16 0.0021 0.12 12.4 6.2 1 21 340 360 340 361 0.94

9 16 0.0069 0.41 10.8 3.0 3 23 369 390 367 390 0.94

10 16 7.4e-06 0.00044 20.1 0.9 1 23 418 440 418 440 0.97

11 16 5.2e-05 0.003 17.5 0.7 1 23 451 473 451 473 0.97

12 16 2.4e-05 0.0014 18.5 2.5 1 23 496 518 496 518 0.99

13 16 0.16 9.2 6.5 3.1 3 23 554 574 552 574 0.94

14 16 0.002 0.12 12.4 3.4 1 23 580 602 580 602 0.98

15 16 4.1e-07 2.4e-05 24.1 1.4 1 23 610 632 610 632 0.99

16 16 0.00027 0.016 15.2 0.4 1 23 638 661 638 661 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.045	2.6	8.2	2.7	2	23	120	141	119	141	0.96
2	16	1.7e-05	0.001	19.0	1.2	1	23	162	184	162	184	0.98
3	16	0.0003	0.018	15.0	4.9	1	23	195	217	195	217	0.96
4	16	4e-06	0.00023	21.0	0.6	1	23	226	248	226	248	0.98
5	16	3.8e-06	0.00022	21.0	2.6	1	23	254	276	254	276	0.98
6	16	0.0057	0.34	11.0	0.1	2	23	284	305	283	305	0.97
7	16	6.3e-05	0.0037	17.2	3.4	1	23	311	334	311	334	0.94
8	16	0.0021	0.12	12.4	6.2	1	21	340	360	340	361	0.94
9	16	0.0069	0.41	10.8	3.0	3	23	369	390	367	390	0.94
10	16	7.4e-06	0.00044	20.1	0.9	1	23	418	440	418	440	0.97
11	16	5.2e-05	0.003	17.5	0.7	1	23	451	473	451	473	0.97
12	16	2.4e-05	0.0014	18.5	2.5	1	23	496	518	496	518	0.99
13	16	0.16	9.2	6.5	3.1	3	23	554	574	552	574	0.94
14	16	0.002	0.12	12.4	3.4	1	23	580	602	580	602	0.98
15	16	4.1e-07	2.4e-05	24.1	1.4	1	23	610	632	610	632	0.99
16	16	0.00027	0.016	15.2	0.4	1	23	638	661	638	661	0.96

Sequence Information

Coding Sequence: ATGGACTACAACAATGCGTACAACAAACCATACTGCGGTGTTTCTCAACCCGTACCTGGACCAAGCTCAGGTTTCTTTCCGCCAAATGGCACAACACCGACGTTCCTTAAGGTGCCCAATCCACCGTACATCAAACAGGAGGTGGTGGCTGATGCAGCAATTCACCGTGGAACCGTGACCCCGCCTGTGAATTATAGCCAAAATCAAAACTATGGCGTTGAAATGGGTGAATCAACCGATCCGGATAAACCACTGTTCTATAGGAACATACCGTACATGACAAACCCCAACACTGTTCCATCGGTAGCCAACTCGATTACGGTGACACCAATCACGGCAGCACCCTCACTTGCTTTAAACTGTGACACTTGTATGAAACATTTCGAGACAAAAGAGAAACTGGACCAGCATGCCAAGACGCACCAAACGTTGGCCGCTGAAGCCATTATTCAGCAGGTACCAATAGTGGCACCATCGCAAAACTTTAGCTGTGACACCTGTCCGAAAACCTTCGAGACGAAGGTGAAACTAGATAAGCATGCCAAAACACACCAACCGCCGGCTGATATCGTCCAGAAGGAATTCAAGTGCCGAATGTGCGACAAAACATTTCGCACGAAAAGTACACTCATATGTCACGAGAAGGTGCACGGTGAGAATGGGCTGGACAATAGTTTCTCGTGCGTGGAGTGCGGGAAAGTGTTTGCGAGCGCGGACAAGCTGCATGTGCATCGACGGTTGCATACGGGCGAAAAACCGTACCAGTGCAAGGTGTGTCTGAAGCGCTTTAACCACCAATCGAACCTGATCGTACACTCGCGCATCCACCAGAAGGTGAAGCAAGCGCTAAAGTGTGCCCGGTGCAACAAGGTGCTCGATAGCGAAGAACGGCTCGCAATTCACATGCGGCTGCACACGGGTGAAAAACCGTACAAATGTTCGTACTGTGACAAGCGCTTCAATCACAAGAGCACCGTTAGTACGCACGAAAAGGCGGCCCACATTGCGGCCAACTCGTTCAAATGCGACCGGTGCCATAAGACGTTCAATCAAAAGTGCCAGCTGCAATATCACGAGAAGCTGCAGGAGGAGCACACGATCGCGTGCACCATCTGTGACAAGGTGTTCTGCTATAAGGCGAGTCACAAGGAGCACATGTTTAAGGTACATTTTCCTCGCCAGAAAAAGGGTGGTAGTGTTGGCGAAACGAGCACCCGTCGGGCTGCTAGCGATGGTCAGGGACGGAATAAATTCAAATGTACTATTTGCGATCGACGGTTCTACTACAAGCGAGCGCTCGAAATGCACATGGGGGTGCATGATGCCCGGCTGGATGTGAACGTGCTCTACTTTTCGTGTAATTACTGCCCGGAAACGTTTACCGAGGAGACGGAGCTAGAAAAGCATGAAACGAAACACGTCTCGGATGGGACAACGGATTTCCTAGAGAACATGAAGGTGCTCGAACAGTCGGCGGACGACAAATTTCGGTGCCCGCTGTGCTTTAAAGGCTTCAACGATCAGCAGGCGCTTCGCGATCACCACAAAACTCATCTCTGTACGGATTCCAGCTGCAGCAAGTGTGTGCCAGCACAGAGTGACGAGTTTGATCTGAAGCGTAGCACATACGACGCAAGCGAAGACACGCGGCCAACGGCGTGCAATATCTGCCACCGTGTTTTACCGTCATTTGAACAATTTCAGAACCATTTCCACTACCATACGACGCGCGTTCCGTTCTACTGCTATCACTGCCGGGAAGAGTTTAGCGGGAAACGCGAGCTGTATGCGCACTCGCGTACGCACTCAACGCGCGAACCAGAATCCTATACGTGCGAAGTGTGCGCGAAGGTATTTTCTACCAAGGGCAACTACAAACGACACCTGAAATCTCATGAAACGGTCCGTGCGTTCGCGTGCGATCGTTGCAGCAAGCAATACGACTACAAGAGTGCCCTGGAGGTACATCTGAAACGTGCGCATGGTATTGAGTTATAG
Protein Sequence: MDYNNAYNKPYCGVSQPVPGPSSGFFPPNGTTPTFLKVPNPPYIKQEVVADAAIHRGTVTPPVNYSQNQNYGVEMGESTDPDKPLFYRNIPYMTNPNTVPSVANSITVTPITAAPSLALNCDTCMKHFETKEKLDQHAKTHQTLAAEAIIQQVPIVAPSQNFSCDTCPKTFETKVKLDKHAKTHQPPADIVQKEFKCRMCDKTFRTKSTLICHEKVHGENGLDNSFSCVECGKVFASADKLHVHRRLHTGEKPYQCKVCLKRFNHQSNLIVHSRIHQKVKQALKCARCNKVLDSEERLAIHMRLHTGEKPYKCSYCDKRFNHKSTVSTHEKAAHIAANSFKCDRCHKTFNQKCQLQYHEKLQEEHTIACTICDKVFCYKASHKEHMFKVHFPRQKKGGSVGETSTRRAASDGQGRNKFKCTICDRRFYYKRALEMHMGVHDARLDVNVLYFSCNYCPETFTEETELEKHETKHVSDGTTDFLENMKVLEQSADDKFRCPLCFKGFNDQQALRDHHKTHLCTDSSCSKCVPAQSDEFDLKRSTYDASEDTRPTACNICHRVLPSFEQFQNHFHYHTTRVPFYCYHCREEFSGKRELYAHSRTHSTREPESYTCEVCAKVFSTKGNYKRHLKSHETVRAFACDRCSKQYDYKSALEVHLKRAHGIEL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -