Basic Information

Insect: Anopheles farauti
Gene Symbol: -
Assembly: GCA_000473445.2
Location: KI915043.1:15315846-15319939[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.00026 0.016 15.2 0.9 1 21 68 88 68 89 0.95

2 17 0.76 45 4.3 0.2 2 12 122 132 121 133 0.88

3 17 3.1e-07 1.9e-05 24.4 4.4 1 23 486 508 486 508 0.99

4 17 3.4e-07 2e-05 24.3 0.5 1 23 514 536 514 536 0.99

5 17 1.6e-05 0.00097 19.0 0.0 1 23 542 564 542 564 0.98

6 17 3.2e-05 0.0019 18.1 0.6 2 23 570 591 569 591 0.96

7 17 2.1e-07 1.3e-05 24.9 4.1 1 23 597 619 597 619 0.99

8 17 4.7e-05 0.0028 17.6 3.5 1 23 686 708 686 708 0.96

9 17 5.1e-06 0.0003 20.6 2.5 2 23 715 736 714 736 0.98

10 17 1.6e-06 9.4e-05 22.2 0.8 1 23 742 764 742 764 0.98

11 17 2e-06 0.00012 21.9 0.1 2 23 770 791 769 791 0.98

12 17 1.4e-06 8.5e-05 22.3 2.0 1 23 797 819 797 819 0.99

13 17 6e-06 0.00036 20.4 4.0 1 23 872 894 872 894 0.98

14 17 2.8e-07 1.7e-05 24.6 0.9 1 23 900 922 900 922 0.99

15 17 4.6e-05 0.0027 17.6 0.2 1 23 928 950 928 950 0.98

16 17 3.7e-06 0.00022 21.0 0.3 2 23 956 977 955 977 0.97

17 17 2.6e-06 0.00015 21.5 1.2 1 23 983 1005 983 1005 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.00026	0.016	15.2	0.9	1	21	68	88	68	89	0.95
2	17	0.76	45	4.3	0.2	2	12	122	132	121	133	0.88
3	17	3.1e-07	1.9e-05	24.4	4.4	1	23	486	508	486	508	0.99
4	17	3.4e-07	2e-05	24.3	0.5	1	23	514	536	514	536	0.99
5	17	1.6e-05	0.00097	19.0	0.0	1	23	542	564	542	564	0.98
6	17	3.2e-05	0.0019	18.1	0.6	2	23	570	591	569	591	0.96
7	17	2.1e-07	1.3e-05	24.9	4.1	1	23	597	619	597	619	0.99
8	17	4.7e-05	0.0028	17.6	3.5	1	23	686	708	686	708	0.96
9	17	5.1e-06	0.0003	20.6	2.5	2	23	715	736	714	736	0.98
10	17	1.6e-06	9.4e-05	22.2	0.8	1	23	742	764	742	764	0.98
11	17	2e-06	0.00012	21.9	0.1	2	23	770	791	769	791	0.98
12	17	1.4e-06	8.5e-05	22.3	2.0	1	23	797	819	797	819	0.99
13	17	6e-06	0.00036	20.4	4.0	1	23	872	894	872	894	0.98
14	17	2.8e-07	1.7e-05	24.6	0.9	1	23	900	922	900	922	0.99
15	17	4.6e-05	0.0027	17.6	0.2	1	23	928	950	928	950	0.98
16	17	3.7e-06	0.00022	21.0	0.3	2	23	956	977	955	977	0.97
17	17	2.6e-06	0.00015	21.5	1.2	1	23	983	1005	983	1005	0.98

Sequence Information

Coding Sequence: ATGCTTGACGCGTGGTTAAAACCCACCGATGAGTTGCGCTTCGAAGCGTTCGGAAGTGATTACGCAAAGTCGCAGGTTCCACTGGCGCAGCAACAACAATCGGCTCCCATCTCGTCCCAGCAGCCGCAACAGCAACCGTGCAAATGCGAATTTTGCGAGTATCTGCAAGCCAACCGGATATCACTGACCGGCGACCATTCGTTTCAGTGCGAATTTTGCGGCGAAGGGTTCGCAAATCAAGTCAGCTTCAATCGGCACCGCTGCGGCAGCACTGACATACAGATCTATCGGTGTGAAGCCTGTCGGCAGGAGTACGGTAGCTCACGGGCACTGTCCACAATCGGAAACTGCGAGCCGAGAGACAAATGTGATATCTGCAATCGAACGTACGTGCAATCCCTACCGGAAGAGCAGGCGGCCTACGGTCCAGCGATGGCTGGTCCAACGCGAACAACGACGACCGCGATCGGATCCGAAACCGGGCCGTTGACCGCAACATCGGTTCTGCCCTCCTTCCCCCCAGCGGTGATAGCTGCCGGTTGCGAGCTGTCAAACGAGAGTGGCAGCGAAGCGAGCGTCAACGTACGATCGATCGTGGACAGTCCCATCGAACAGCATGACCTCAGCAGTATCGATCCGTTCGGGTCCGACAGTGAATGTCTTGAGCAGTTTTTTGCTACCGATGCAACCTCCACTCCACCCAGCACCACCAGCACCAGCACGAACACCTTGCAGTGTCAGCAGCCCGTGCCAAACAGTGCCAACATCGGAAGCCTCCTTCCAACCGCCAACGCCAGCACACTGCATCATCCGGAGTCGGCCAAAACGTACTTCGTGCTCGGAAATGTGGAGCAATTGCAGCAGTTTCACGCAGCAGTTGCGATACAACAACAACAGCAACAACAACAGCAACAACCAGCACCACCATCCAACACCAATACTCCACCGGCCACCAATAGCTTCCATCATGTTCATCTTCCACCACCCGGACCTGGGTCCCATCAGCAACAGCTGCTGCTGCAACAGCAGCAGCAGCTAGCTCCGGTACCGATCTCGCTGCAGAACGCGGCCCCGAACACGGCGGGTTCGCTTCTGCCCAGCGAGCACGAGGTCACTAGCTTGCAGCAGTACGATCAGTACGATGATGAGGACTACTCGTCCATGTCCGAAGATGAAGCTATTGTTCCAATAGAGCCTTATGCGAAGTCACCCAACCAGGACCACGCCAAGACGGAGCTCCCGATCCAGGAGACCATCGTAGACACCAGCACCGGTACCGGCACCACCGGCAGCGCCGTTTCTCTGTCCCAATTCGCGCCGGGTTCGAACGCCCCACGAGACGACGCCTCGCTGGGAAAATGTGATTCGTCATCGTCGGCGGTCGGCGTGACGCGGCCGCCACCAACACGATGCTCCTCGCTCGCCTCCGACGGTTCGATCAGCATCGATCGACCGTACAAGTGTCACATCTGCGACCGATCGTACCGCAATCAGAAGAACCTCAAATCCCACCTCAAAGTACACGAAGGCATTCGGGCGTACCAGTGTGAGATCTGTGGCAAGAATTTCTCCGGCTCCAGCTATCTGGTGATCCACCGACGCCGCCACACCGGCGAGCGTCCGTTCAAGTGCGCGACGTGCGGTAAGGCGTTCGTCGACTCGCGGGCCCTTGCCGTGCACGCCCGGCTCCACAGCGGCGAACGGTTGAAGTGCGAAAAGTGTGAGAAAACTTTCTCGAGCGTGAGCGCCCTCACGGTGCACAATCGCCTGCACACCGGCATCCATCCGTACAAATGTGAGCTGTGCGGCAAAACGTTTCCCCAGTACAATAACCTGAAGCACCACATGAAAAAACACGAGCAACCAAATTCGGCCGACACCAGACCGCTGCCCCTGGCGTTGGCCCCTGCGTTGTCGAACGGGGTCAGCACAACGAGCGCCAGTTCCGACCACCTTCCGGAGCGAGCGGGTTCCACGGCAGCGGATGCGAACGCGAAACTCACCGCACCCGGGCATATGGTGGCCAGCTCGACTACCGGGCCCTCGTCGTTCGAGCACAAGTGTCACATCTGCGGCAAGCTGTACAAAAACTCCGACGACTTGCAGGAACACCTCACCCAGCACGGCAAAGATCGTCCGAACCAGTGCGAGTTCTGCTCGAAGGTGTTTCCACGCTCCTCGCACCTCATCATCCACCGGCGCCGCCACACCGGCGAGCGACCGTTCAAGTGCAAATACTGCGACAAGGCGTTCGTGGACTCGCGGGCCCTTTCCGTCCACACGCGTTTGCACACGGGCGAGCGGGTGAAGTGTGAGATCTGCGAGAAAACGTTCGCCAGCTCGAGCGGCCTAATCGTGCACCGGCGCATTCACACCGGCGTCCATCCGTACAAGTGTGAGTACTGCGAAAAGTCGTTCGCCCAGTCGACCGCACTTAAATACCACCTGAAGAAGCACGATACGGCGCTGCTGCCAACGACGACCACGCCCGAAGCGGCCGACTCGGTGAGCACTCGACTTCTGGCGCTTCCGGCCGGTGCGAAAGACACCGCCGAGGCAGGCCAGTGCCCGGCGTACGGTGACGAATCCGCGTCCGCAAATGGCAACGATCGGCACAAGTGCACCGTGTGCAGCAAGATCTTCCGTTCCTCCGAGTACCTGGTGCGCCATCGGCGTACGCACAGCGGCGAGCGACCGTACCAGTGCGAGATCTGCGGCAAAAACTTCTCCACCATGAGCTACCTGGTGATCCACCGGCGCCGTCACACGTCCGAGCGTCCGTACAAGTGTAGCTCGTGCGAGAAGGCGTTCGTCGACTCGCGAGCCCTGCAGGAACATGCCCGCCTACACACGGGCGATCGCGTACGGTGCGAGATCTGCCAGAAGACGTACTCCAGCGTCAGCAATCTGATCGTGCACCGGCGCATACACAGCGGTATCCATCCGTTCGAATGTGACAGCTGCGGGAAATCGTTCGCGCAGAAAAACGCACTCAAATATCATCTCAAGAAACACATCAAACAGGACTAG
Protein Sequence: MLDAWLKPTDELRFEAFGSDYAKSQVPLAQQQQSAPISSQQPQQQPCKCEFCEYLQANRISLTGDHSFQCEFCGEGFANQVSFNRHRCGSTDIQIYRCEACRQEYGSSRALSTIGNCEPRDKCDICNRTYVQSLPEEQAAYGPAMAGPTRTTTTAIGSETGPLTATSVLPSFPPAVIAAGCELSNESGSEASVNVRSIVDSPIEQHDLSSIDPFGSDSECLEQFFATDATSTPPSTTSTSTNTLQCQQPVPNSANIGSLLPTANASTLHHPESAKTYFVLGNVEQLQQFHAAVAIQQQQQQQQQQPAPPSNTNTPPATNSFHHVHLPPPGPGSHQQQLLLQQQQQLAPVPISLQNAAPNTAGSLLPSEHEVTSLQQYDQYDDEDYSSMSEDEAIVPIEPYAKSPNQDHAKTELPIQETIVDTSTGTGTTGSAVSLSQFAPGSNAPRDDASLGKCDSSSSAVGVTRPPPTRCSSLASDGSISIDRPYKCHICDRSYRNQKNLKSHLKVHEGIRAYQCEICGKNFSGSSYLVIHRRRHTGERPFKCATCGKAFVDSRALAVHARLHSGERLKCEKCEKTFSSVSALTVHNRLHTGIHPYKCELCGKTFPQYNNLKHHMKKHEQPNSADTRPLPLALAPALSNGVSTTSASSDHLPERAGSTAADANAKLTAPGHMVASSTTGPSSFEHKCHICGKLYKNSDDLQEHLTQHGKDRPNQCEFCSKVFPRSSHLIIHRRRHTGERPFKCKYCDKAFVDSRALSVHTRLHTGERVKCEICEKTFASSSGLIVHRRIHTGVHPYKCEYCEKSFAQSTALKYHLKKHDTALLPTTTTPEAADSVSTRLLALPAGAKDTAEAGQCPAYGDESASANGNDRHKCTVCSKIFRSSEYLVRHRRTHSGERPYQCEICGKNFSTMSYLVIHRRRHTSERPYKCSSCEKAFVDSRALQEHARLHTGDRVRCEICQKTYSSVSNLIVHRRIHSGIHPFECDSCGKSFAQKNALKYHLKKHIKQD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -