Basic Information

Insect: Anopheles epiroticus
Gene Symbol: -
Assembly: GCA_000349105.1
Location: KB670214:250528-254191[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 1.7e-05 0.0011 18.8 2.1 1 23 278 300 278 300 0.99

2 8 0.00028 0.017 14.9 4.9 1 23 310 332 310 332 0.96

3 8 0.078 4.8 7.3 5.0 3 23 358 379 356 379 0.94

4 8 1.3e-05 0.00077 19.2 0.9 1 23 428 450 428 450 0.97

5 8 0.00025 0.015 15.1 0.5 1 23 461 483 461 483 0.95

6 8 0.00011 0.0068 16.2 3.0 1 23 508 530 508 530 0.99

7 8 3.4 2.1e+02 2.1 0.2 4 16 535 547 532 549 0.82

8 8 0.32 19 5.4 2.2 3 23 566 586 564 586 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	1.7e-05	0.0011	18.8	2.1	1	23	278	300	278	300	0.99
2	8	0.00028	0.017	14.9	4.9	1	23	310	332	310	332	0.96
3	8	0.078	4.8	7.3	5.0	3	23	358	379	356	379	0.94
4	8	1.3e-05	0.00077	19.2	0.9	1	23	428	450	428	450	0.97
5	8	0.00025	0.015	15.1	0.5	1	23	461	483	461	483	0.95
6	8	0.00011	0.0068	16.2	3.0	1	23	508	530	508	530	0.99
7	8	3.4	2.1e+02	2.1	0.2	4	16	535	547	532	549	0.82
8	8	0.32	19	5.4	2.2	3	23	566	586	564	586	0.94

Sequence Information

Coding Sequence: ATGGAATACAACAATACGTTCAACAAGCCTTACTGTGGCATTTCCCAGCCCATTCCACCAGCACCACCTGGCAGCTCTGGTTATTTTCCAGCAAATGATACTACACCTACGTTCCTTAAGGTTCCCAACCCTACGTATATCAAGCAGGAAGTGGGTACAGTGAGCGGGGAATCGGTCATCCACGGTGGAACCGTTACGCCACCGGTAAATTACAGTCAGCATCAGCACTATGGCGTGGCCAATTACGCTGAGTCGGGTGACACGGAGAAACCTCTGTTTTATCGCAAAACGTTCGAGATGCCGTACCTACAGAATCCCTACCTGCAACCGCAATTGCATCAGTATGCGCAGCATCCTCATCCATTGCACCCCAACCATCATAATCAAcagcagcagcagcagcagcCGACGCCGCCGCCACATCACCACAACCATCAGCTGCCCCATATCCCGACGATATCTCATCTGCAGCAGATCCACCATCAGCAACCTCCTTTGACTGTGCCATCCGATATGCATTCACCACAGCAACTGGGATCGGACCATTTacaacgcccccagcaacaacagcagcagcaggaacaacaacaacaacaacaacagcCGAGCTTCCACGAATATTTTGACCACCTGGACCCATCCTCGATGGAACCGTACGCGTACGTGCTGCAGAAACCTCTCCCACCACCAGCACCACCATTGCAACCTCAGCCGATCCAGTCCAGTGAAACGCCTTCTCCAATGCCTACTTCGTTTCCCGTAGAAACGACGTCTCCTTCGGTAGCGCCTTCCCCGTACGAGGCGCGTGAACCGATGGGCGAAAAAGTGCGCTTTAAATGTGAAACCTGTCCCAAAACGTTCGACACAAGGGTGAAGCTGGACAAGCACAACCGCACGCATGCCGCAACCGGTGGCGCTCAGGCTGAGTTCAAGTGCCGGATGTGTGACAAGACGTTTCGCACAAAAAGTACACTCATCTGCCACGAAAAGGTGCATGGAGAAAACGGGACGTTCAATCAAAAGTGTCAGCTGCAGTACCACGAGAAGCTGCAGGAGGAGCACACGATCGCGTGCGATCACTGCGAGAAGGTGTTTTGCTACAAGGCCAGCCACAAGGAGCACATGTTTAAGGTGCACTTTCCGCGGCCCAAAAAGGAGCACCAAAAACGGACCAACGATCATCCTCAGTCGGATGGGGATGGGAAGACAGGTGGTGGTGATGGGCCACCAGGTAATGCAATTGCCACCAGCGCAGGGAATGGCAATCATGGGCGCAACAAGTTCAAATGCACGGTGTGTGATCGACGGTTTTACTACAAGCGAGCGCTCGAGATGCATATGGGAGTGCACGATGCATCGCTGGATGTGAACGTGCTTCACTTTTCCTGCAACTACTGTCCGGACACGTTTACGCAGGAGGAATCGCTACAGAAGCACGAAGCCCAACACGTGGCCGATGGGACGACAGATTTCCTGCAAAACATGAAAGCGCTCGAACAGTCAGAACAGTCCGACGGTGGCTTCCGCTGTCCGTTATGCTTTAAGCGTTACGACGATCAGCAAGCGTTACGCGAGCACCACAAAACGCACCTTTGTGCGTTACCCGACTGCGGCAAGTGTACTGCAGCGCAAAGCGATCTGTTCGATCTCACGCGCAGTACGTACAATGAGAGCGAAGACATGCAGGCGACGGCGTGTAACGTTTGCCACCGGGTGCTGCCAACGTTCGAGGCGTACCAGAACCACTTCCACTACCATACGGCCCGCCCCAATAAGCTCCACCATCACGGGGAAGTATTTCACCACCAGGAAGCTGATCGTCCACAAGAACGCCGTGCAGAGCGATCCGCCGAGTCCTCGAACCTGCACAAGGAAATCGTTACTGGCGTGGCCCTGTGCATGTGTGATAATTACCTTTCGCTGACAACGATCTACGATAATGGTGGATCCGTACGAGCCAATGATCTGAATCGCGCCAACCACAATGGCCGCCATGTTAGGGTCAAGATCAGACCCCGAGTCGGCAAAAATCTGGGCGGTGTAGTTGATCAGTGCGAAGCATCCGGAAAGCTGATTAAGCGATACCAGCACCAAGCCGATGAGCAGAGCCTTACGTGCTGA
Protein Sequence: MEYNNTFNKPYCGISQPIPPAPPGSSGYFPANDTTPTFLKVPNPTYIKQEVGTVSGESVIHGGTVTPPVNYSQHQHYGVANYAESGDTEKPLFYRKTFEMPYLQNPYLQPQLHQYAQHPHPLHPNHHNQQQQQQQPTPPPHHHNHQLPHIPTISHLQQIHHQQPPLTVPSDMHSPQQLGSDHLQRPQQQQQQQEQQQQQQQPSFHEYFDHLDPSSMEPYAYVLQKPLPPPAPPLQPQPIQSSETPSPMPTSFPVETTSPSVAPSPYEAREPMGEKVRFKCETCPKTFDTRVKLDKHNRTHAATGGAQAEFKCRMCDKTFRTKSTLICHEKVHGENGTFNQKCQLQYHEKLQEEHTIACDHCEKVFCYKASHKEHMFKVHFPRPKKEHQKRTNDHPQSDGDGKTGGGDGPPGNAIATSAGNGNHGRNKFKCTVCDRRFYYKRALEMHMGVHDASLDVNVLHFSCNYCPDTFTQEESLQKHEAQHVADGTTDFLQNMKALEQSEQSDGGFRCPLCFKRYDDQQALREHHKTHLCALPDCGKCTAAQSDLFDLTRSTYNESEDMQATACNVCHRVLPTFEAYQNHFHYHTARPNKLHHHGEVFHHQEADRPQERRAERSAESSNLHKEIVTGVALCMCDNYLSLTTIYDNGGSVRANDLNRANHNGRHVRVKIRPRVGKNLGGVVDQCEASGKLIKRYQHQADEQSLTC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -