Basic Information

Insect: Anopheles epiroticus
Gene Symbol: -
Assembly: GCA_000349105.1
Location: KB669626:132016-138271[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.00029 0.018 14.9 6.5 1 23 88 110 88 110 0.98

2 13 7.5e-05 0.0046 16.8 2.9 1 23 148 170 148 170 0.98

3 13 6.2e-05 0.0038 17.0 0.7 2 23 174 195 173 195 0.95

4 13 0.00026 0.016 15.1 0.9 1 23 205 227 205 227 0.99

5 13 0.69 42 4.3 0.1 2 23 407 429 406 429 0.90

6 13 0.012 0.76 9.8 2.3 1 21 1176 1198 1176 1200 0.95

7 13 1.3 79 3.4 0.6 2 20 1210 1229 1209 1233 0.91

8 13 2e-07 1.2e-05 24.9 1.4 1 23 1269 1291 1269 1291 0.98

9 13 0.00093 0.057 13.3 0.6 2 23 1363 1385 1362 1385 0.92

10 13 0.00046 0.028 14.3 1.9 1 23 1401 1423 1401 1423 0.95

11 13 0.033 2 8.4 6.8 1 23 1429 1451 1429 1451 0.98

12 13 0.00072 0.044 13.7 2.4 1 23 1459 1482 1459 1482 0.97

13 13 0.33 20 5.3 2.0 1 23 1491 1513 1491 1514 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.00029	0.018	14.9	6.5	1	23	88	110	88	110	0.98
2	13	7.5e-05	0.0046	16.8	2.9	1	23	148	170	148	170	0.98
3	13	6.2e-05	0.0038	17.0	0.7	2	23	174	195	173	195	0.95
4	13	0.00026	0.016	15.1	0.9	1	23	205	227	205	227	0.99
5	13	0.69	42	4.3	0.1	2	23	407	429	406	429	0.90
6	13	0.012	0.76	9.8	2.3	1	21	1176	1198	1176	1200	0.95
7	13	1.3	79	3.4	0.6	2	20	1210	1229	1209	1233	0.91
8	13	2e-07	1.2e-05	24.9	1.4	1	23	1269	1291	1269	1291	0.98
9	13	0.00093	0.057	13.3	0.6	2	23	1363	1385	1362	1385	0.92
10	13	0.00046	0.028	14.3	1.9	1	23	1401	1423	1401	1423	0.95
11	13	0.033	2	8.4	6.8	1	23	1429	1451	1429	1451	0.98
12	13	0.00072	0.044	13.7	2.4	1	23	1459	1482	1459	1482	0.97
13	13	0.33	20	5.3	2.0	1	23	1491	1513	1491	1514	0.96

Sequence Information

Coding Sequence: ATGGCTGCAAATGAGGAAAGCTCGTTCGAGTACGCAATAGTGCAAATCAAAGAGGAAGCACTGTCTGACCCTGAAGAAGCAATACCTGCTACAACGAACAATAATTATTCAGAGAATGGCTACAAAAAAGGAAGCAAACCACGCCGAAGCACTAGAACCGCAGGTCGCCCCTCGGTTCGGAATGTTAAGCAGGAACCCAACAACAATACATTGAAAACAAAAGCCAGCAAATGGTCAACAGACGCAGAAGCCGTATCGCAGTACCAATGCGAACATTGCCACGAAACGTTCGACAGTAACTCACGCCTTAGTCGGCATAAACGACAGCACCGGTACGAAAACTGTCCCATATGCGCAAAAAAGATACAGATCGATTTTTTAAAGTATCACATTGGCCAGATGCACGCCGGTGGCAAAGAACCAACAGTAGCAAACCTGCCCTATCAGTGTGCGCTCTGCGAGAAATCGTTCTACTATGCAAATCATCTGCAAAAGCACAAGCAGGTGCACGAAAAGAAGAGCTGTCCGGTGTGCGGAGAATCGTTCAGACAGTCTTACCTAAAGTATCACATGACCAGGATGCATCCGACCGATGCGGCCAATCCGGTCAAATACCGGTGCAGTGCATGTAAGGAAACATTTTACGATAGAAATCTCCTCTGGGCACACCAGCAGAAGCACAAAAAACTTTCATCGAACCATCTCAACTCACCGCTGCACGACTCTCCCGGTTCACCAACGAATCCACTCACATATGCACCCTCATCGCCATACTTTTCTTCCATCTCGGCAAGCCACACCAGTGGGCCGAACGATGTTATTTTACCGAGCATTTTCGTCAAGATTCCTACCCAAATCAACCAGCAGTACCAGCAGGAGAGCCGGTTGCGCACCCACCATAGTACGGCAAACGAGATCAAGTGCGAGGAACGGTCGGAATCGATAAAGAGTGAGGTGGCCGACACGCGGGTCAAGCTTATTACAagcagcagcagcagcagcagcagtagtaccagcaacgacCCATTACCGGACATTATCGATAACTATCTAAACGATACGGATGCGGGCGTACAGCCGGAAGTGGAACCGCCGATACTGCGGTTGTGTGATCGTTGCCCATTCGCCACCTTGTCGGAAGTGCGGTTGAACGACCATCGTCAGGCAAGACATGTGACAGGAGGTGTAGAATCGCAGGTAGGGACAGTGGAAACGTTAAATTGTCCGGTTTGTGAGAACAAATTCTACAAAGCTACCGTGCTAGAACTGCACCTGGCAGAGGACCATGAAATGATGGCCAGCGAGGTGGAAGCATTAAGTACTAGGCGTATTGTTAGACATGCCACACAGTCATCGATGGTTGACAGCCGGTGTGCCGCAGTTGAGTCTTCAAGCGAACCAGCAGGAGCGACCTCAAATGAAATGCAACCGACAAACCAGGGCAAAAGCCGCATATACATCAAGAACGTACAGCTGCTTAAGAAACCGGATGTGATTGCCCAAGAAACGCGGCAAGAGAACGACGTTGCACAAGGCCAGGGTCAGTTACTCTCAGCGGAACAGAATCCATCTTCGACACACGGAGGCTCTCTTCAGGACAGCCATCAGTTATCGCTAGGGGAAGACATGTTACCGCCACCGATCGCTCAATCGCTAGATCTACCGCCGCACGCATCCATCTCACAGCAACCGTGTGCCGTCAATGGTAACAAAATTTTCATCCGCAGTGTGTCGTTGCTGCAGAATGTGAATTTTGTTGCATCGGCCGAAAACATGCTTACCAGTGGGAGTGGCAATCGGTACAACACAGcaccaccaccaccaccaccaccaccGTCTTATTTGAGCATGGATTGTGCAAATGGCGATGGAACAAGTTCTCTTCTAGACACGATGAACGGTGGGTACAGTACGGGTATGACAAAACCGGCACCTTCAAATAGCGCCCAATCGAGGGGCAGTCGTATATACATTAAAAACGTTGACATATTGCGGAACCCACTGATAACGCTCGATGACCCGCCAGTGTCGAGCACAAATTCGCTTTCTGTAACCTTTAGCGAACCAATCACGACAAGCAGAGCAAGTAGCTGCGAAAGCATTATTTGTACATCTACACCACCGGCCACTGTCGTGGAACAACAGCAACCGAGTGCTCCGGAACCATGCCTAACGAATACAGCTTTAGGGCCCGCGACACAAACGAATGACCAATCGCTTCTTCATGGTACGGAAGTAAGCTATAGCGCTGGCCCCGATGAAATGGGAAATGGGAACAGATCGCTACCGCTAACCGTTGAGCAAGGGCCACAGAACTTGCTGATGCTGTTTTCCACCTCACAGGACGGTACGATCGGTACAGCAGTAGGAGGTGATCCCAACTTTTCCTATCTAACCGCAAACACGAACTCGAATGTACAAAACTCAGAGTACGATGCGCATTTACCCACGCCAACGGTTATTTCCTGTGATGGGCAACAGCAACAGACCGCTCAGCAGCAGCCACCGTCAAAGAAGAAGAGTAAGATATTCATTAAAAACATCAGCGTGCTAAAACAACCGACAATACATTTAAAATCGGTCGACGAAGTCAATCTGATGACGTACGATGAGCTACAGTTGCAGAACATACTGCCCACCGTTGGTGGAATGTCCTCGCAAACAGCGATGGATGGTAACCAGGACCCGACGGGCACGCTCGAGCAACATGAAACGCGGGACCTGCTCGTGAATACCGATCGCACGGACAAACTGTTCAGTGGAATGATAGAGATGGGCGATAATCTTCCCCTTCATCCGGACGAAGGAAACGTGGTCGACGACAACGACCACGACGTTATGGATGGGTACCATGAGTCGGATCTTGGCTACGGTGAGCTTAGCGATGTGTGTGACTTTACCGAAGGTTTCAACGATCGAGACGATCCCGGTGGAGGAGAGATCGATCTAACGGCGGGACTATCCACAGGAAACGAACCGAACGGCAGCGGTAACTTCGAAACAGAAACGACACACTGTGACTTTTCCTTACCGGCCACCGACGTTACGAACGACATTATTCTGCTGCAGGAAGAATCGGATGCGAACGAGAAGATCACACCGAACCACGAATGGACAGCGCTTGAGACGACGGCAGGGCATGGAACGTCACCGTTAGTGCAAGACATTATACTACAACCGATGGATGGAACGGAAATGTCCGTTGCCACCGTTGCTAGTAGTGACCGAAGAGAGGAAGATCTACTGCTCGATACCCAGCAGGTGATCAACCTTGATCCTCCCAAGGAATATTATCGCCCGGAGAGCGAAACAATCGCAAATTCTAATGCCATTGAACCGGAGCAACAGGTGATGATGGCGGAAAGTTTAGCCGCTTCCCCGGAAGAGGAGACTATATCACCGCTCACTACCACCCCGCAGGAACCGGATCGTCCACGTACCCGTGGACGTCCCAAGGGAGCAAAGCAAACCGGGATTACAAAGCTAAAGAAACTCTACACCAACCTAACGGCCGAGGAAGAAGGCTATAAGTGTGACGTGAAGGACTGTGGCGTACGTTTTCGACAGCCCGATCGACTTGAGTATCATCGCAAGTGTCACGTTGTGGGAGACGGCACCAATTCCATCCACTGTCCGGAGTGTGGTTCAATCGAGTACCGTAACTGGAACACGCTGCACACGCATCTGTGGCGCGAGCATGCCATCGATATGGAGCTGTACGCGTGCCATCTGTGCAGCTTCAAGACGCCCGTCCTGTGCCGGTTGAACAATACGCACATGAAGATCCACTCGGAGGAGCGTAACTTCAAGTGTGCCATCTGCGGGAAAGCTTTCAAGAACAATAAGCAGTTGCGCAACCATCGGCGGTGGCATCGGGAACCACAGCCGACGCCAGAGCCGACAACGCCACAGCAGCAACTGCAGGACAATCCTCCAGTTTCAGTGCTGGAGGAAGAGCAACCGATTGCAAGACAGATCAGTCAGCCCAAAGAGACTGCTCCAAGTACTGTACCAACTACGAACGATCCACCGTTGGCAGATAAACAGAAATCGACAGCGAAATCGAGCACACTGCAAAGCTCGATGAAATGCGTCAAGTGTGGGTTACGGTTCGCGGGCAAGCGGCAACTACGAACGCACATGGACGCGAAACATCCCACCGAACCAGGCGAGCACTCGACAGAGGTCCCTGTCAGCAAGCATCGCTGTCTGCTCTGTGGCATGGTGTTCCGGACGCGCTATCTGCTGCAGTCGCACTCTGCGAAACATTCGGACGAGAAGCGGTTCAAGTGTGAGCATTGCGAGTACACAACGAACGATCATAATGCGTTCAGGCGGCACAAGATGCGGCACAGCACGAAGGGTGGACACATGTACAAGTGTAGCTATTGCGATTACAGCAGCATTCAGAGTACAACCTACAGGAAGCATCTGGAGCGTATGCATGCGGAGGTAGCATCGGCACTGCTCTACAAGTGTGCCAAGTGTCCGTTCGTGTCGATCAGTGAAGCCAAATATCAGCTTCATCGAACGAAACACCACGAGGAGGATGCCTCGACCGAGCAGAGCGGACAAGTAGAGCAGGGACAAGTGATGGAATCGGTGGAAGCGACTGAATCCGATTATCAGCAGAGACAGTGTGAGAGCGTCAACTCGGACGTGGTAATTGTGGAGCAGCGTGATATTGATACTGGCAGTATTAGTGCTTCACCGATGGAGGATCCAACCGCAGCGGCTGCAACTATTGGCGGTGGTGGTCTACAAATCATCCAGCATCCTATCATCCGGCCGGCAATGTTTGCGAACAATTTCTCCAAGGTAGACAACTTCTACGGCTATCAACCGCATCACCACCACCAGCAGCAGCAACAGCAGCTTGGTCAGTCCATTATGGTGAAGCTTCCTGAGGCGACGCCACGTAGTATGTGTCCTTCCTCTCAAGTGTCCTACGCGATTGACATACTGCCAACGATGACCACTTCCATGCCCGTTCCTGTTTCTCTCCCGGTTGGACAAATACCCGAGCAGCATGAGTACTTGCATCTCGCTGCTACGACGGGCGAAGTTCTCATGAGGGAACTTAACTAA
Protein Sequence: MAANEESSFEYAIVQIKEEALSDPEEAIPATTNNNYSENGYKKGSKPRRSTRTAGRPSVRNVKQEPNNNTLKTKASKWSTDAEAVSQYQCEHCHETFDSNSRLSRHKRQHRYENCPICAKKIQIDFLKYHIGQMHAGGKEPTVANLPYQCALCEKSFYYANHLQKHKQVHEKKSCPVCGESFRQSYLKYHMTRMHPTDAANPVKYRCSACKETFYDRNLLWAHQQKHKKLSSNHLNSPLHDSPGSPTNPLTYAPSSPYFSSISASHTSGPNDVILPSIFVKIPTQINQQYQQESRLRTHHSTANEIKCEERSESIKSEVADTRVKLITSSSSSSSSSTSNDPLPDIIDNYLNDTDAGVQPEVEPPILRLCDRCPFATLSEVRLNDHRQARHVTGGVESQVGTVETLNCPVCENKFYKATVLELHLAEDHEMMASEVEALSTRRIVRHATQSSMVDSRCAAVESSSEPAGATSNEMQPTNQGKSRIYIKNVQLLKKPDVIAQETRQENDVAQGQGQLLSAEQNPSSTHGGSLQDSHQLSLGEDMLPPPIAQSLDLPPHASISQQPCAVNGNKIFIRSVSLLQNVNFVASAENMLTSGSGNRYNTAPPPPPPPPSYLSMDCANGDGTSSLLDTMNGGYSTGMTKPAPSNSAQSRGSRIYIKNVDILRNPLITLDDPPVSSTNSLSVTFSEPITTSRASSCESIICTSTPPATVVEQQQPSAPEPCLTNTALGPATQTNDQSLLHGTEVSYSAGPDEMGNGNRSLPLTVEQGPQNLLMLFSTSQDGTIGTAVGGDPNFSYLTANTNSNVQNSEYDAHLPTPTVISCDGQQQQTAQQQPPSKKKSKIFIKNISVLKQPTIHLKSVDEVNLMTYDELQLQNILPTVGGMSSQTAMDGNQDPTGTLEQHETRDLLVNTDRTDKLFSGMIEMGDNLPLHPDEGNVVDDNDHDVMDGYHESDLGYGELSDVCDFTEGFNDRDDPGGGEIDLTAGLSTGNEPNGSGNFETETTHCDFSLPATDVTNDIILLQEESDANEKITPNHEWTALETTAGHGTSPLVQDIILQPMDGTEMSVATVASSDRREEDLLLDTQQVINLDPPKEYYRPESETIANSNAIEPEQQVMMAESLAASPEEETISPLTTTPQEPDRPRTRGRPKGAKQTGITKLKKLYTNLTAEEEGYKCDVKDCGVRFRQPDRLEYHRKCHVVGDGTNSIHCPECGSIEYRNWNTLHTHLWREHAIDMELYACHLCSFKTPVLCRLNNTHMKIHSEERNFKCAICGKAFKNNKQLRNHRRWHREPQPTPEPTTPQQQLQDNPPVSVLEEEQPIARQISQPKETAPSTVPTTNDPPLADKQKSTAKSSTLQSSMKCVKCGLRFAGKRQLRTHMDAKHPTEPGEHSTEVPVSKHRCLLCGMVFRTRYLLQSHSAKHSDEKRFKCEHCEYTTNDHNAFRRHKMRHSTKGGHMYKCSYCDYSSIQSTTYRKHLERMHAEVASALLYKCAKCPFVSISEAKYQLHRTKHHEEDASTEQSGQVEQGQVMESVEATESDYQQRQCESVNSDVVIVEQRDIDTGSISASPMEDPTAAAATIGGGGLQIIQHPIIRPAMFANNFSKVDNFYGYQPHHHHQQQQQQLGQSIMVKLPEATPRSMCPSSQVSYAIDILPTMTTSMPVPVSLPVGQIPEQHEYLHLAATTGEVLMRELN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -