Basic Information

Insect: Anopheles epiroticus
Gene Symbol: -
Assembly: GCA_000349105.1
Location: KB672098:294238-298191[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.019 1.2 9.2 4.2 1 20 198 217 198 220 0.93

2 16 3.7e-05 0.0022 17.8 1.8 2 23 273 294 272 294 0.97

3 16 0.041 2.5 8.1 2.7 1 23 301 324 301 324 0.92

4 16 7.8e-06 0.00048 19.9 2.7 1 23 338 360 338 360 0.97

5 16 0.0096 0.59 10.1 1.7 3 23 368 389 366 389 0.96

6 16 3.4 2.1e+02 2.1 0.2 1 23 492 515 492 515 0.90

7 16 2.5e-06 0.00015 21.4 1.1 1 23 543 565 543 565 0.93

8 16 6.9e-06 0.00042 20.0 2.1 1 23 571 594 571 594 0.98

9 16 0.21 13 5.9 2.2 1 23 603 626 603 626 0.95

10 16 0.00084 0.051 13.5 1.5 1 23 805 827 805 827 0.96

11 16 0.012 0.75 9.8 2.7 1 23 833 856 833 856 0.95

12 16 0.013 0.77 9.8 0.8 1 23 868 891 868 891 0.97

13 16 1 64 3.7 3.4 2 23 951 972 950 972 0.95

14 16 3.4e-06 0.00021 21.0 2.3 1 23 997 1019 997 1019 0.98

15 16 0.0066 0.4 10.7 0.4 1 23 1025 1048 1025 1048 0.96

16 16 0.0076 0.46 10.5 1.3 2 23 1063 1085 1063 1085 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.019	1.2	9.2	4.2	1	20	198	217	198	220	0.93
2	16	3.7e-05	0.0022	17.8	1.8	2	23	273	294	272	294	0.97
3	16	0.041	2.5	8.1	2.7	1	23	301	324	301	324	0.92
4	16	7.8e-06	0.00048	19.9	2.7	1	23	338	360	338	360	0.97
5	16	0.0096	0.59	10.1	1.7	3	23	368	389	366	389	0.96
6	16	3.4	2.1e+02	2.1	0.2	1	23	492	515	492	515	0.90
7	16	2.5e-06	0.00015	21.4	1.1	1	23	543	565	543	565	0.93
8	16	6.9e-06	0.00042	20.0	2.1	1	23	571	594	571	594	0.98
9	16	0.21	13	5.9	2.2	1	23	603	626	603	626	0.95
10	16	0.00084	0.051	13.5	1.5	1	23	805	827	805	827	0.96
11	16	0.012	0.75	9.8	2.7	1	23	833	856	833	856	0.95
12	16	0.013	0.77	9.8	0.8	1	23	868	891	868	891	0.97
13	16	1	64	3.7	3.4	2	23	951	972	950	972	0.95
14	16	3.4e-06	0.00021	21.0	2.3	1	23	997	1019	997	1019	0.98
15	16	0.0066	0.4	10.7	0.4	1	23	1025	1048	1025	1048	0.96
16	16	0.0076	0.46	10.5	1.3	2	23	1063	1085	1063	1085	0.90

Sequence Information

Coding Sequence: ATGGATCTGGAGCCAGAGCAAGAGCCGGAACCGCTGGTTGACGATGATCCAGTGGATGTTCCGAACTCGAACCCCGAGACGTACTGCCGGTTTTGCTTCTCGGAGAACGAGGTGGAACCACTGTTCTCTGCGAACGGCTCCCAGGCGAGTGCCGAGCTGCTGGACCGCATATACGAATGTATCGGTATCAAGCTGACGCGCAAAGAATACTGCCCCAGCGGCATCTGCTGGTCGTGCACGCTTACACTGGAGGAGTTTCAATGTTTTCGCAACCGCTGCTTGAAATTTGACGCTCTCGTGCGCAGCCTGCTCCAGCCGACGGTGAAATCGGAACCGACCGGCTACCGCACCGCTACCCCGACCGACCGGCTGTGCAAAACGGAGGATAATTCCAACCATAAGCAGTCGGTGAAAAACAATGGCGGCTTGTCGACGACATACAAAACGGAGCCTACTAGCAACCGTACCGCTACACCGACCAGCGGGCTCTCGAAAAAGGAGGAAAAGATCAAGCAGGTGGCGATGAAGGCGAAAAACAACGGCGCCGGTGAAATGCAGAAAGGGGTGGCCGGGGCCTCGGTGCCGTTAAAATTTAAATGCCAGTTTTGTCCGCGCAGATTCAAGCACCGAATGTATCTGGATCAGCATCTCTGGAAGCATCGGGACAGGATTGCGGAGGAAGCCGGTGTAGACATGAAAAAACTGCCTATTGTCAATGCAAACGGCAGCACGGCGGTGGTTGGCATCAAAACGGAAGGTTCGGTTGGATCAAGCAACACCATTGGCGTTGCGGCGGCTGGTGCGGACCGGCCGATTAGCTGTGAGTATTGTCCACGCAAGTTTACCCGCCGGATGTACTATATGCAGCATCTGCGCAGGCACAAACCGGACGAGCGGTTGTTCCGCTGTCGGCACTGCCCGCGCAGCTTTGCGTCGCAGATGCGGCGGACGGGTCACGAGCGAAAGATACACGGTCAACTGAGCAATCCTAAGTCGGACGAAAAGGACACCTTCTCCTGCCCCAAGTGTGCAAGAGTCTTTAAACACCGATCGTCATTACGCATGCATATGCTGAACCACGACGGACAGCTCCCGTACGGTTGCGATATCTGCAACTGCCGATTTTACAGTGTGAGCTATCTCGCCGTTCACAAGAAGCGCTACCACGGGCCGAACGCGGCACGTACCCTGGTCAACGGCACCTCCATTCCGTGTCACTACTGTTCGCGTTGGTTTTTGCGCGAGTGCGACCGCTCCAGCCACATCAAGCAGATGCATGCAGACATGCATGCAAGCAAGGAGTCAGCGGTCGGGTTTAACGAGCTGCTCGATGACTGCCCACCGGCGGACAGCGAGGGTCTGACCGATCCGGAAATGCTGCCCCCGAACGTGCACGAACCAATGATGGTTATTAAGGAGGAGGAACCGGACGTGAGCGAAACGCCTGGACAGAGCGGTGCGGACGGACTTCAGTTCTACTGCTACTCGTGTGCCATGCCGTTCGACACGGAAGATATGTACTCGGAGCATCTGGACGATCAGCACCCGTTTGGCGGAGAGCAGCTGATGGATCAGCTGCAGCCTGCCTCGCCCGGTCCAGTTGGACAGGAAGAGCCGGCAAACCTGTTCAAGTGCCCGTACTGTCCGAAAACATTCACGCGCAAGTGGAGCATGACCCAACACATTCCTACACACATGACCAGGAAGGGCTACCAGTGCGAATACTGTCCAGCGATGTTCACGCGCAACGAATACTTGCGCACGCACCGGAAGCGCAAGCATCCGACACTGCCAGAGACGGGCGCGTTCAAGTGCAGCTACTGTCCCCGCCTGTTCCACATGGCCCGCTACAAGAAGGTGCACGAACGAATTGCGCACATTAAGAAGGGCGATGTACTGCCGGAAGGAGAGGACACAGTGAGCAGCGAGCGGTCGGCGATTGACAGCACGGTGGCTAAGCGACCGGACGAGAGCAGCAGCAGCAGTATCAGTGCAGCCCACGGGCGACATTCCCGTGCGTCGGACTTCTTTGATCAAGCGTCGAACGATGCACACAGTGCTGCAGCTTCCATGCAAGGAGACTACACGGGCTTAGAAGAGTCCTCGCGGTTGGTTGTGCTGCTGGAGCGACTGCCAGAACACGAGCTGGAACAGTATCGTTGGCAGCTGGAGGTGTATGCAAGCATGCTGCCGGTGGTTAAAATCAAGCAGGAATTGATGGATCCCCAGTACGGTGATGACAGCGAGCTCACGTACGCTAAAGAGTGCAACGAAGAGGAGGATGAGCAAGACGACGAAGACGACCGTGAGGACGCAGCAAGCGGCTCGGAGCTCAATCCTGACGATTCGACAAACGATTCCGGAAAGCAAACGCTGCTGAAGCGAAAGCGAAGCAAGTTCGGTATCACCCTGCACCCATGTCCGCAGTGCTCGAAGCTATTCAAATCCCGAACGGCACTTCGAATGCACGTGCTTTACCACAGTGGCGAACTTCCGCATCGGTGCGACGAGTGTGGCGTACAGTTCATGCGGTACAACCAGCTCGAGTATCACAAATCCCGGTACCACGGGGCCAACAGTGCGACGACGATGGCGGCCCAATACAGCTGCGACTACTGTCCGCGCATCTTTCTGCGCAAGCAGGACCGCACCACGCACCAGCTGATGGTGCACGCGCGCGACCAggcggaggcggcggggctggcggggctgAAGAAGTCCAAGCGCAAGGACTACGTGTGCCGGGTGTGCGATGCTGAATTTGAGAAGTATAGGCGGTGCGTGAGGCACATCACTCTCCACCATCTGGGCGCGGATGGTGCGCCGGAGTGCAAGCCGATCAAGCTTTGCCACTGTCCCATTTGCAGCGGCATCTACAAGAAGCGCGACGACTGGCACGAGCATCTGAACGAGCATCCGAGCGTGCGGCCGCATCACTGTGAGCAGTGCATCCGGCGGCGCAGGAAAGCGTCCAGCCGGAAACAGGTGCACCGCTGCTCTTACTGTCCCAAGGCGTTCGAGCACAAGCCAAACCTGGCTTCGCATTTGCGCATCCACAAGCAGCAGCTACGGTTTCCGTGCAGCGAGTGTGGCGTCTTGTACGATCGGTACCGCGATCTGCTGACGCACCAGAGTCGCTACCATCCGGACAATCCTTCCGACGCGATCGTCCGCGAACCGATGCCGCAGTGTCATTTTTGTCCGCGTGTTTTTACCCGTCTGCGCGACGTCAAGTATCACGAGGAGCAGGTACATGCGGATCAGGTTATACCCGAGGCAGCTCCAGCCGGTGAGCAAGATGTTAACAAAGAAGGGAGGGTACCTGAAACCGAGGAGCAGCAGCAGCAGCCACAGCAGGAAGACGAGGAATTGATGACGACGTTCGGTTTCGGGCCGGAGATGTTTCCCGAGACCGACCTGATAGAATCGGTGTTTAACGTAGCCGACCAACCGATCAAACCGGATCCCGATTCGGAACTCTCGCCAAACGGCGAGGTGATTGATTGA
Protein Sequence: MDLEPEQEPEPLVDDDPVDVPNSNPETYCRFCFSENEVEPLFSANGSQASAELLDRIYECIGIKLTRKEYCPSGICWSCTLTLEEFQCFRNRCLKFDALVRSLLQPTVKSEPTGYRTATPTDRLCKTEDNSNHKQSVKNNGGLSTTYKTEPTSNRTATPTSGLSKKEEKIKQVAMKAKNNGAGEMQKGVAGASVPLKFKCQFCPRRFKHRMYLDQHLWKHRDRIAEEAGVDMKKLPIVNANGSTAVVGIKTEGSVGSSNTIGVAAAGADRPISCEYCPRKFTRRMYYMQHLRRHKPDERLFRCRHCPRSFASQMRRTGHERKIHGQLSNPKSDEKDTFSCPKCARVFKHRSSLRMHMLNHDGQLPYGCDICNCRFYSVSYLAVHKKRYHGPNAARTLVNGTSIPCHYCSRWFLRECDRSSHIKQMHADMHASKESAVGFNELLDDCPPADSEGLTDPEMLPPNVHEPMMVIKEEEPDVSETPGQSGADGLQFYCYSCAMPFDTEDMYSEHLDDQHPFGGEQLMDQLQPASPGPVGQEEPANLFKCPYCPKTFTRKWSMTQHIPTHMTRKGYQCEYCPAMFTRNEYLRTHRKRKHPTLPETGAFKCSYCPRLFHMARYKKVHERIAHIKKGDVLPEGEDTVSSERSAIDSTVAKRPDESSSSSISAAHGRHSRASDFFDQASNDAHSAAASMQGDYTGLEESSRLVVLLERLPEHELEQYRWQLEVYASMLPVVKIKQELMDPQYGDDSELTYAKECNEEEDEQDDEDDREDAASGSELNPDDSTNDSGKQTLLKRKRSKFGITLHPCPQCSKLFKSRTALRMHVLYHSGELPHRCDECGVQFMRYNQLEYHKSRYHGANSATTMAAQYSCDYCPRIFLRKQDRTTHQLMVHARDQAEAAGLAGLKKSKRKDYVCRVCDAEFEKYRRCVRHITLHHLGADGAPECKPIKLCHCPICSGIYKKRDDWHEHLNEHPSVRPHHCEQCIRRRRKASSRKQVHRCSYCPKAFEHKPNLASHLRIHKQQLRFPCSECGVLYDRYRDLLTHQSRYHPDNPSDAIVREPMPQCHFCPRVFTRLRDVKYHEEQVHADQVIPEAAPAGEQDVNKEGRVPETEEQQQQPQQEDEELMTTFGFGPEMFPETDLIESVFNVADQPIKPDPDSELSPNGEVID

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -