Aepi000454.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles epiroticus
Gene Symbol
-
Assembly
GCA_000349105.1
Location
KB671916:4368-11137[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 2.4 1.5e+02 2.6 3.8 1 23 239 262 239 262 0.90
2 11 3.1 1.9e+02 2.2 4.2 1 23 268 291 268 291 0.94
3 11 1.7e-05 0.001 18.8 1.7 1 23 314 336 314 336 0.98
4 11 9.1e-05 0.0056 16.5 0.5 1 23 343 365 343 365 0.98
5 11 0.0013 0.078 12.9 0.1 1 23 384 407 384 407 0.97
6 11 0.0023 0.14 12.1 0.2 1 23 424 446 424 446 0.96
7 11 8.1e-05 0.005 16.7 0.1 1 23 570 593 570 593 0.96
8 11 0.00019 0.011 15.5 7.6 1 23 658 681 658 681 0.98
9 11 0.00073 0.045 13.7 1.4 3 23 689 709 687 709 0.97
10 11 0.017 1 9.3 1.1 1 23 724 746 724 746 0.99
11 11 1.3e-05 0.00078 19.2 0.0 2 23 763 785 762 785 0.95

Sequence Information

Coding Sequence
ATGGAAGAACCTTCGCAGGTGGCGAACAGTGAATCGAATTCAATGGTAGTAACAGCATCCTTGCCGAACGCACCGGATAAAGCTGTACAGCAATCTTCCGTTGTTGTCGGTACGAGAATGTTGGTAATCTGCCGGATCTGTCTCTCCTCCCGTCCACGTATGATATCCATTCACAGTCCGGTACCAGAGTACGATCAGAAAACGCTCTATACCATGCTGCTATCCGTGTGTTTGCCGCTCAATCAGCGTGAAACGGTGCAGGGCTTTCCGGAGCAGATTTGCCGCAACTGCCAGTGGAAGCTCCTGTCGGCGTACGACCTGTATGAGACGACGCTTGCAAGCGATGAGCAACTGCGTGCTGAAACGAAACTCGGAGCGACACGTAAAACCATTCCTCGTGAAGTGACCAGTCCGGAGAGTGCACTCGACAGAAAAGACACAGACAAAGATAACCTAATCTGTGTGAAGGAAGAGACACCTGACGACGGATACGACGAGCATTACGGGTCGGGCAGTAGAGCAGAAGATGACAGTAGCACAATTTATGATGAGAGCGGGGAGATGAGCACGATCAGCGTCCAGCCAGATGTAAGCTTACTTACGCAGAGCAGAGAACAGGGCGAGGAGGAAGAGGACTTGCTGGAGGAAACGAAACCCGACCCGCTGGAAGCATTCATTGCCGAACACTACCAGATGGACGAAGACAGCGGTAACCATATCTGCCGGCTGTGCAAGCAAGACTTTGCCTACAAGAGCCAGTGCCGGGTGCATATCGTCCAGAGACACAATCCGGCCAAACCGTTCAAATGCGACGTTTGCTTCTGTACGCTCACCAGCCATCTGCGTTTGGTACGACACAAGATTGTTTCCCACGGGGCCGGCCAGATCAAGCGCGAGGACGTGATCGAAGCGCCGAATGATAGTACCGGTGAGATGACGTACACCTGTCCGATTTGCCGCAAGGTGTTCAACTCATCCGTACGCTTCAAGCGCCACAAAAATGTGCACGTTGCGCACAATCGGCCGTTCAAGTGTGAGGTGTGTCTGTACCGGTTCGCTACCAAGCCACAGCTGACGCAGCACGCTAAGGTGCATGAAACAAAACCGGCCACGGATGGGCTCTCGCCCGGGAGTTCCGAGGTAGGTGAATTCCCGTGCGATCGCTGCGAGGAAGTTTTTGTGGCGAAGCGTGCGCTTACGATGCACCTGAAGAAGGCGCACCAAGTTTACCGGGTGCCCGGTGGTGCGCGACCAGAAGAGAGGAATGAATACGTATGCATCATCTGCAAGGCAACGTTTGCGCGCGAAACCGTCCTGAATACGCATATGAAGATGCACGAGCTACTGGCAGCGGAGAAGGAAAAGGAACGGCGGCTCGATTTCGAGCGTTTGGTTAAGCAGGAGCTGCAGCAACAGATGCTGCTCAATGTGCCGCCCTTACCACCATTGTCCCCGGAGGTGATTGATCGATCCGCTTGTGTACTGGAACCGTTTGCATTGGGTTTGGTACCGGTGGCAAAACCAGGCACGGATACACCAGGTACGACACCGGGCACTGGTCCGGGCACAAACAACAATAACAGCACCAGCATTAACAACAATAGTCCCCCGGGCGGTGGTGGTGGTGGCTCCGATGGTCCGAGTGGGTTGGTACTGGGCAGTAAAAGAAAGTTACCAATAGCATCGGCGCCTCCGAGTGATATGGCATACGTCTGTCCCGTCTGTGAGATGGAGTTTGACGAACGGGACGCGCTGAAAAAGCATCAAAAGGAGCAACATACCCGACTACAGGTTGGTATCGTGTCGTCGAAACTCGGCGAACCCGGCACCCCAACGAATGATGACGTTGTTGAGCATTTGGAGCACGAGGATTCACTAGACAACGATGGTCATATCGCTGCCGGCCTGGTACCGATTGATGATGTCTCGGGGAGCACTGTGTCTGGTCCCTCGGACGAACCACCGTCTCAGTTCCAGTGCAATCTGTGCCATAAAAAGTTCCCCTACAATTGCTACTTAACGATGCACATGCGAAAGAATCACGACAAATCGAAACCGTACGGCTGTAAGGTGTGCCACTATCGTTTCGGATACCGTGGAACACTGCTGCGGCACCAGCTGATACACTCGTCCCAGCGCGTCCAGCCGGGATGCCACGGTTCGATCATCTTCAAATGCCGCATCTGTTCGGCCAAATTTCTCGAATTGAAACAGCTCAATGTGCACCTGAAAACACACCGAAAAGTGCCGGAAGAATCGGCACCAAACCGGCAGGTGCAGTTGATACGTTGTAACGAGTGTCCACAAATCTTTAGCGATCCGGATCAGCTAGCACAACACATGGTAAAGGagcaccagcagcacggcaatacggatgatgagttgtacgacgtcgatcaaatgatccaacaacagcagcagcagcagcagcagcagcagcagcagcagcagcagcagcagcacgatcatcaccgaATGACCACTGGGCTGCTAAGGAATCCTTCCTCAGCATCTTTAAAGGGCGATGCGGAAGGCGGACGTACCGCCAGCATCAACGATCTCAAGCATAGTTCCGAACAGCCGACAGTCGGCCACGGTGAAGCTTACATCAACGATGATGTATCTATAATTAAGCTAGAGCCACTCGATTAA
Protein Sequence
MEEPSQVANSESNSMVVTASLPNAPDKAVQQSSVVVGTRMLVICRICLSSRPRMISIHSPVPEYDQKTLYTMLLSVCLPLNQRETVQGFPEQICRNCQWKLLSAYDLYETTLASDEQLRAETKLGATRKTIPREVTSPESALDRKDTDKDNLICVKEETPDDGYDEHYGSGSRAEDDSSTIYDESGEMSTISVQPDVSLLTQSREQGEEEEDLLEETKPDPLEAFIAEHYQMDEDSGNHICRLCKQDFAYKSQCRVHIVQRHNPAKPFKCDVCFCTLTSHLRLVRHKIVSHGAGQIKREDVIEAPNDSTGEMTYTCPICRKVFNSSVRFKRHKNVHVAHNRPFKCEVCLYRFATKPQLTQHAKVHETKPATDGLSPGSSEVGEFPCDRCEEVFVAKRALTMHLKKAHQVYRVPGGARPEERNEYVCIICKATFARETVLNTHMKMHELLAAEKEKERRLDFERLVKQELQQQMLLNVPPLPPLSPEVIDRSACVLEPFALGLVPVAKPGTDTPGTTPGTGPGTNNNNSTSINNNSPPGGGGGGSDGPSGLVLGSKRKLPIASAPPSDMAYVCPVCEMEFDERDALKKHQKEQHTRLQVGIVSSKLGEPGTPTNDDVVEHLEHEDSLDNDGHIAAGLVPIDDVSGSTVSGPSDEPPSQFQCNLCHKKFPYNCYLTMHMRKNHDKSKPYGCKVCHYRFGYRGTLLRHQLIHSSQRVQPGCHGSIIFKCRICSAKFLELKQLNVHLKTHRKVPEESAPNRQVQLIRCNECPQIFSDPDQLAQHMVKEHQQHGNTDDELYDVDQMIQQQQQQQQQQQQQQQQQQHDHHRMTTGLLRNPSSASLKGDAEGGRTASINDLKHSSEQPTVGHGEAYINDDVSIIKLEPLD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-