Basic Information

Insect: Anopheles epiroticus
Gene Symbol: L
Assembly: GCA_000349105.1
Location: KB671643:207730-213257[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.44 27 4.9 5.7 1 23 3 25 3 25 0.98

2 17 3.6e-06 0.00022 20.9 3.7 1 23 31 53 31 53 0.99

3 17 1.1e-05 0.00068 19.4 0.3 1 23 59 81 59 81 0.98

4 17 6.3 3.8e+02 1.3 0.1 2 23 176 199 175 199 0.74

5 17 0.054 3.3 7.8 0.1 2 23 241 263 240 263 0.96

6 17 0.15 9.4 6.3 0.2 1 23 582 604 582 604 0.95

7 17 0.093 5.7 7.0 0.0 1 23 641 663 641 663 0.93

8 17 0.00024 0.015 15.2 0.2 1 23 714 737 714 737 0.93

9 17 0.0017 0.11 12.5 0.8 1 23 744 767 744 767 0.97

10 17 0.0018 0.11 12.4 1.5 1 23 799 821 799 822 0.96

11 17 0.31 19 5.4 0.2 1 23 1087 1111 1087 1111 0.91

12 17 0.00044 0.027 14.3 0.2 2 23 1120 1142 1119 1142 0.96

13 17 0.0032 0.2 11.6 0.1 1 23 1149 1171 1149 1171 0.98

14 17 1.7 1e+02 3.1 1.2 2 20 1179 1197 1179 1200 0.94

15 17 0.0023 0.14 12.1 0.3 1 23 1387 1409 1387 1409 0.96

16 17 0.0072 0.44 10.5 0.0 1 20 1419 1438 1419 1442 0.95

17 17 0.027 1.7 8.7 0.3 1 23 1450 1472 1450 1472 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.44	27	4.9	5.7	1	23	3	25	3	25	0.98
2	17	3.6e-06	0.00022	20.9	3.7	1	23	31	53	31	53	0.99
3	17	1.1e-05	0.00068	19.4	0.3	1	23	59	81	59	81	0.98
4	17	6.3	3.8e+02	1.3	0.1	2	23	176	199	175	199	0.74
5	17	0.054	3.3	7.8	0.1	2	23	241	263	240	263	0.96
6	17	0.15	9.4	6.3	0.2	1	23	582	604	582	604	0.95
7	17	0.093	5.7	7.0	0.0	1	23	641	663	641	663	0.93
8	17	0.00024	0.015	15.2	0.2	1	23	714	737	714	737	0.93
9	17	0.0017	0.11	12.5	0.8	1	23	744	767	744	767	0.97
10	17	0.0018	0.11	12.4	1.5	1	23	799	821	799	822	0.96
11	17	0.31	19	5.4	0.2	1	23	1087	1111	1087	1111	0.91
12	17	0.00044	0.027	14.3	0.2	2	23	1120	1142	1119	1142	0.96
13	17	0.0032	0.2	11.6	0.1	1	23	1149	1171	1149	1171	0.98
14	17	1.7	1e+02	3.1	1.2	2	20	1179	1197	1179	1200	0.94
15	17	0.0023	0.14	12.1	0.3	1	23	1387	1409	1387	1409	0.96
16	17	0.0072	0.44	10.5	0.0	1	20	1419	1438	1419	1442	0.95
17	17	0.027	1.7	8.7	0.3	1	23	1450	1472	1450	1472	0.95

Sequence Information

Coding Sequence: ATGCCATTCAAATGTGAGTACTGCGCCCGGCTGTTTAAGCACAAACGATCGCGCGATCGCCACACGAAGCTACACACCGGCGATCGGCGCTATCGCTGTCTGCATTGCGAGGCGGCATTCTCCCGAAGCGATCATCTGAAGATACACATGAAAACACACGACAACCAGAAACCGTTCCAGTGTACGATCTGCAACCGGGGTTACAATACGGCCGCTGCCCTGACGAGCCACATGCAAAACCACAAGAAGCAGCTGGCACTTACCGGCAGTCCAAATCTCACCTACAGTCCACGCTCCACCACAAGCTCCCTTTCGAgtggtggtggtagcggtggtggtggtggtggtAAGCGCCAAAGTGCCAAGTTCTCGCCCTACTCCAACGATCCGCTGCTGCTGATGAGTCGTAGCAATAGTGCCAAACTTTCCGCCTCGCTAGCAAAAGGTGGTTCCAGCAATCGAACTCCAACGCCCGGCAGTGCTGGTGCCACTCCGGGAAGTGGTCACCATCATCCGGATCTGCTTTCCTGCCCGTACTGTACGCGAACGGATTTCGGTTCGCTCGAACAGCTCGGCCTACACGTGCAATCGATGCACGGTGGACACGGTGCTGGTGGTGGTTTCATGCCATCGTTTGCACCGGGTGGTGGCCGGCGTGCCGTAACTCCCGATGGCAGTTCGCCCCTTTCACTCGGTTTAGGTGGCCCGTATCCCCCGATCACCTGCGAGTTCTGCACGATGAAGTTCCCAACCGTGCCGTTAATGTTTGCCCATCTCAAGACGGCACATCTGGACCGGTTGGCATCACCATCGAACGGTGGTGGTGGCGccaccaacaccaccaccaccaccaccaccacGGGATCACGCCCGCCGAGTGGGTTCCATTCGCTCGATCACTTTAACAAGACGCTGCTCGGCAATGCTTTCCCCTCGTTCTACGGTGGCATGTCCGGTGGCAGTGTGAAAGCGGAACATCGGATAATGACCGGTGGTGGACGTGATGAAAATGGAAACGAAGCGGGAGAACCGGGTAGGAAACGCAGGCGGAGAGGGGACGATGAGGATACGGTGGAACGTGACCGTGCGGGAAGTTCGAAGCAGGAAGAGGAAGACATGGAAGCGAATGATGGTGACgagcaggaggaggaggaggagcaggaggaagaggaggaggaaaggcaagaggatgatcatggtgaggaagaagaaagtgaagaTCATGGTGCGATCAATCGAAGCGAATCCATGGACTTTAAGGATACCACTACTTCGATCAAGCAGGAGCGAAAGGAGGATCTTGATCAGCACGGTGTATCGCCCTCGACTTCAGCACGATCGTCCCCGTGTGATTCGCTCGAATCGGGTAGTGCGCGTCCACGCAGTCATCCATCCACGGGAAGGAACAGCCCAGCGGAGCAGCTCACACCGACCGATCTAAGCCAGCCGAAGATGAAGCGGTTCAAGATAGAATCTCGCGACGATGAGGAACTACTACCGCTAGCGGATGGTGAGAGCAGGAAGACGATGCCGGTGACGTGTACTGGTCGAACTGGCCAAGCTGTTCGGGAGCATCACAAACACCGTAGCACAAGTCGAAGAGATGGAGAAGCAAAGGAGCAACATTCGCTGATACTCTCGTCCAGTGTCCCACACGCTCAACCGATGGCTGCTCCGACATCTACCGGACCGTCGTTATCGACTGCGGCCCAGCAGCACGTCCATCAACATCCGCCGGGGGCTTATCTCTGCAATCAGTGTAATGCCGCCCTACCCGACTTTGAGTCCTTCCGCACGCACCTGAAAGCACATCTCGAGCAGAGTGCGGCAGCGGCTGCGATGCGCCTGTCCGGCGAGCATGGAACCGGTTCGTCCTCCAACTGCACCACTCCGGGTGGAACGTCTCTTTCGCACACGACCTTTCTCTGCCAGCAGTGTGGAGCCGCGCTAAGCAGCTCAGCGGAGTACGAGCAGCACACGATTGGCCACTTTCTCGTGATGGCAGTGGAGTATCGATGTCAGGCAGCGACGGCGGCGGCAACCGCGACGGAACCTGGAACTAGCTGCAACAGCAAGGGCACCTTCGGTAAGGTGGAAGACCTGCACAAGCATCTGTACGAGGGCCATATGCAGCTGCTGTACAAGTGTACGGTGTGCGGGGAAACGTTCGAGTCGAAGGTCCAGGTGCAGGTCCACTTTGCCGTAAGTCACTCGGTGGAGGTGAAGCTGTACCGGTGTTCGGCGTGTGCTGAGGTGTTCCGTTCCGAGCGTGATTTTCGGCAACACATACGGAATCGACACTTGACGGCGGGCGCTGTGCAGTGTATGTTCTGCAGGATGGTTTGCTCCTCCGAGCTGGAGATGCACTTCCATCTTGCTTCACACGCCAGGAAGTACAAATGTCCTGCTTGTCCAGAATCGTTCCACGTGGAGTTCCTGCTCGATCGACACATTCAAACGCACCACAGCCAGAAGGAAACGGGCTCACCAAACCAACCACCATCATCATCTACACCCTCCGCCACAACTTCCAGCACGAACCCTATACCCATACCCTCGACGGCGCCAACAACAGCCGTGTCCACAGCACCGACATCTACCGTCACAGGGCTGGACTATCTACATCTGCACGGTCAGATGGCGGCAATGGCAGCAGCAGCTGCGTGGCCTAGTCTCTATCAAACTGCCAACAAGTTCTACAACAATCCACTGCAAGTGGACACCCTAAGTCAGCTCAAGCATCCACAGCACCTTCTGCACGGATTTTACGACACAATGCTCGGGAAGGCACAGCAACAAACACGCGGCAGTGCAGCACCATCCTTCCTGGTCGATCCCTCACCCGGTGGCAAGAAGAATCCGTTTGCCGGTCACTCGCCAAACGCACTGCTCGGGGGGCTGGGCTATGGAGCAGTGGCAAATTCCCAATCGCAAAGAATTCAACCCGGATCTCATCATACCCTCAATGGTTCCTCGTCCTCTGGTTTGTATTCCCCAGAGGAGGGCAATAACGGTGGTTCGGGTGTGCCAACAAATAACAGCTCGAAGCTTTACTCTCCCATTGCCATGATCCAACGGTATGGTGTTGAAGGTGGCGTACCTTCTCGTACGGAATCACCTACACCCGAGCAAcagcagcagcagcagcaCCAACAGCCGACTAATCGCAAGTCAAGTCAAGGACAACAGTCAGGTCCGAAGGTGTCCACCGGCACAGTGACACCACAAATCGTGACCCCTGCTGGTGCGAACAGCTGCTACAGCTGCGGCATCTGCGAACGATCCGATTTTAGTACGGAAAGTGAGGTCCAAACGCACCGTAAAATTGTGCACAATCTAAAGACGGGCGTTAGTTTGCGGTGTGCGTACTGCAATGGGGACTTCCGCTCAAGGAATGAGCTGGAAAATCACATGAAAGTGGCACACAATACGGGGGGCGGCAAGCACAAGTGTTTGATCTGTGACGAGATCTTTCCCTCGCCGGCGGTGCTAGCCGAGCACAAGCTGACTCACTGCAAGGTCGGTGCGTCAGGGCGCTGTTCGCACTGTAGTCTCCCGTTGCCCGATGCGCACACCTTCAAGCAGCATCTGCCAGCTCATCAGCAAGCGATCGGTGGATCTATTGGAGCGGCCGGAGGAACCACTACAACTCCTTCCAGCGGAAGCACACCGGGTACAACTGCTAGCTCCTCCAACGGGCAGAATGCGTCTTCTTCGGGAAATTCAACTGGCGCGAGTACGAGCGCCAATGGCGACCAGGATCGATTCCCTCAGCAGTGCATCTGTTGCCGGCAGACGCTCAATTCTGAGTTTGAAATTAGTCTTCATGCCAAATTCCACACCAAATCGCTTGACACAAACGAGCGCACGTGTGCCCTCTGTCTGGAGCCGCTACCATCGCAGCCCGATTCCAGCACCAAGATTTGTGATCCCTGCCTAAAGCGCCACAATTTCCCTACGAAGCTTCTCTCGATGAACTTCCTAAAACCTGCCTCGACGACCACGCTCGGTCAACCTTCAGCTCACGTACCAATCGCAACCACCGGTATGCCACCGGAAGGAAGACCACCAACATCCACCGCGTCCTCGGTTCTTCAGCAAGAACAGCAAGGAGGGACGACGCCCACCGCCAATCTACGGGAAGGTTCCTCTTCCGCGTTCCAGTGCAATCTCTGCAAGAAACCACTGCCAACGAGCCAAAAGCTTCAGGAGCACCTGATCGACCACACGTTTGCTGGATGTGAAGAGCGGGGTTACGTTTGTTACCTTTGTTCTGCCGTCTTTACCTCCTCCGCCGGGTTGCAGGCCCATTTGCCGCTGGCACACTCGAACGCTGCCGCCAAACCGTACGACTGCGAGCGGTGCGGTGTGGCGTACTTCTTCCGCGCCGAACTGGAACATCATCTGATCGATCACGAGCTGGGAAGAACGATGAGACCGCCGCCGTGCGACGAGTGGCACAACACCACGATACGGAGGAACTCCCCGATGTCTGAGGAAGACGACACGGAAAAGGATGGCCGTGCATCAGCAGCAGCAGGCCAAATCAAGCAGGAACAGTGTGAACCGCCGGAGCAGGAACAGGATGGACCATCATCGTACGATCAGAAGGATGGAGATTTTAGTGTTGAGGACGAATATCAACATGCTGGAAACGAACAACAAGATGAAGAAGTGAATATGGAACAAGAGCATAACGAAGAACCAACTACTCACGCTGGTGATTCCGAATGTGACAGCAATCCACATCAAGACGAGCAGGACGGTGACGATCGTGAGGATCACCCGGAAGAAGTGCTTGATGAAGATGAGATGGAAAACGAGAAGCATCGTCACGGCCAAGAACAGGATGGTGACGATGATGAAGAAGAATATATTGAAGTCGAACACACGACGATGGATGATGGTGGTGGTGGTGGAGCAAGAAGCGCCAAGTCAACCGAAGATCGTCACCGTAGACCTTCGAGCATGTTGCTCAACGGTGGGAAGGATTTCTCAGCGCTAACGTCCTCGACGGCAGCGTCGACAGCTCTTCCGGTTGTAACTGCGGCTGAATGA
Protein Sequence: MPFKCEYCARLFKHKRSRDRHTKLHTGDRRYRCLHCEAAFSRSDHLKIHMKTHDNQKPFQCTICNRGYNTAAALTSHMQNHKKQLALTGSPNLTYSPRSTTSSLSSGGGSGGGGGGKRQSAKFSPYSNDPLLLMSRSNSAKLSASLAKGGSSNRTPTPGSAGATPGSGHHHPDLLSCPYCTRTDFGSLEQLGLHVQSMHGGHGAGGGFMPSFAPGGGRRAVTPDGSSPLSLGLGGPYPPITCEFCTMKFPTVPLMFAHLKTAHLDRLASPSNGGGGATNTTTTTTTTGSRPPSGFHSLDHFNKTLLGNAFPSFYGGMSGGSVKAEHRIMTGGGRDENGNEAGEPGRKRRRRGDDEDTVERDRAGSSKQEEEDMEANDGDEQEEEEEQEEEEEERQEDDHGEEEESEDHGAINRSESMDFKDTTTSIKQERKEDLDQHGVSPSTSARSSPCDSLESGSARPRSHPSTGRNSPAEQLTPTDLSQPKMKRFKIESRDDEELLPLADGESRKTMPVTCTGRTGQAVREHHKHRSTSRRDGEAKEQHSLILSSSVPHAQPMAAPTSTGPSLSTAAQQHVHQHPPGAYLCNQCNAALPDFESFRTHLKAHLEQSAAAAAMRLSGEHGTGSSSNCTTPGGTSLSHTTFLCQQCGAALSSSAEYEQHTIGHFLVMAVEYRCQAATAAATATEPGTSCNSKGTFGKVEDLHKHLYEGHMQLLYKCTVCGETFESKVQVQVHFAVSHSVEVKLYRCSACAEVFRSERDFRQHIRNRHLTAGAVQCMFCRMVCSSELEMHFHLASHARKYKCPACPESFHVEFLLDRHIQTHHSQKETGSPNQPPSSSTPSATTSSTNPIPIPSTAPTTAVSTAPTSTVTGLDYLHLHGQMAAMAAAAAWPSLYQTANKFYNNPLQVDTLSQLKHPQHLLHGFYDTMLGKAQQQTRGSAAPSFLVDPSPGGKKNPFAGHSPNALLGGLGYGAVANSQSQRIQPGSHHTLNGSSSSGLYSPEEGNNGGSGVPTNNSSKLYSPIAMIQRYGVEGGVPSRTESPTPEQQQQQQHQQPTNRKSSQGQQSGPKVSTGTVTPQIVTPAGANSCYSCGICERSDFSTESEVQTHRKIVHNLKTGVSLRCAYCNGDFRSRNELENHMKVAHNTGGGKHKCLICDEIFPSPAVLAEHKLTHCKVGASGRCSHCSLPLPDAHTFKQHLPAHQQAIGGSIGAAGGTTTTPSSGSTPGTTASSSNGQNASSSGNSTGASTSANGDQDRFPQQCICCRQTLNSEFEISLHAKFHTKSLDTNERTCALCLEPLPSQPDSSTKICDPCLKRHNFPTKLLSMNFLKPASTTTLGQPSAHVPIATTGMPPEGRPPTSTASSVLQQEQQGGTTPTANLREGSSSAFQCNLCKKPLPTSQKLQEHLIDHTFAGCEERGYVCYLCSAVFTSSAGLQAHLPLAHSNAAAKPYDCERCGVAYFFRAELEHHLIDHELGRTMRPPPCDEWHNTTIRRNSPMSEEDDTEKDGRASAAAGQIKQEQCEPPEQEQDGPSSYDQKDGDFSVEDEYQHAGNEQQDEEVNMEQEHNEEPTTHAGDSECDSNPHQDEQDGDDREDHPEEVLDEDEMENEKHRHGQEQDGDDDEEEYIEVEHTTMDDGGGGGARSAKSTEDRHRRPSSMLLNGGKDFSALTSSTAASTALPVVTAAE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -